The Salmonella typhimurium flgM gene, which encodes a negative regulator of flagella synthesis and is involved in virulence, is present and functional in other Salmonella species.


:FlgM inhibits the flagella-specific sigma factor FliA and is involved in the mouse-virulence of Salmonella typhimurium. In recent experiments, we observed that: (i) a flgM gene that could function to negatively regulate flagella synthesis was present in a variety of salmonellae; and (ii) the flgM gene derived from Salmonella species that are not normally virulent in mice could complement the S. typhimurium flgM mutant for virulence. Our results suggest that a functional flgM has been retained in most, and perhaps all, Salmonella species, regardless of the motility or virulence phenotype of the strain.


FEMS Microbiol Lett


Schmitt CK,Darnell SC,O'Brien AD




Has Abstract


1996-01-15 00:00:00












  • Molecular characterisation of rough strains of Vibrio cholerae isolated from diarrhoeal cases in India and their comparison to smooth strains.

    abstract::Sixteen of the 18 Vibrio cholerae rough strains isolated from hospitalised diarrhoea patients were found to contain O1 serotype-specific (wbe) genes and all currently known virulence genes. Expression of the regulatory element ToxR was evident in these strains. Cholera toxin production ability of the rough strains was...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: De K,Ramamurthy T,Faruque SM,Yamasaki S,Takeda Y,Nair GB,Nandy RK

    更新日期:2004-03-12 00:00:00

  • The interaction of phage and biofilms.

    abstract::Biofilms present complex assemblies of micro-organisms attached to surfaces. they are dynamic structures in which various metabolic activities and interactions between the component cells occur. When phage come in contact with biofilms, further interactions occur dependent on the susceptibility of the biofilm bacteria...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章,评审


    authors: Sutherland IW,Hughes KA,Skillman LC,Tait K

    更新日期:2004-03-12 00:00:00

  • Immunological characterization of the Prochlorothrix hollandica and Prochloron sp. chlorophyll a/b antenna proteins.

    abstract::Polyclonal antibodies were prepared against the major antenna chlorophyll (Chl) a/b-binding protein from the prokaryote Prochlorothrix hollandica (Burger-Wiersma et al. (1986) Nature (Lond.) 320, 262-264). Immunoblotting experiments on Triton X-114 phase-partitioned P. hollandica thylakoids revealed that the antibody ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Bullerjahn GS,Jensen TC,Sherman DM,Sherman LA

    更新日期:1990-01-15 00:00:00

  • Phospholipids of Clostridium perfringens: a reexamination.

    abstract::We have identified phosphatidylethanolamine as one of the major phospholipids of Clostridium perfringens by two dimensional thin layer chromatography of the intact lipids and of their deacylation products and by liquid chromatography followed by mass spectrometry of the intact neutral phospholipid fraction. The princi...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Johnston NC,Baker JK,Goldfine H

    更新日期:2004-04-01 00:00:00

  • RD1 region in mycobacterial genome is involved in the induction of necrosis in infected RAW264 cells via mitochondrial membrane damage and ATP depletion.

    abstract::It was shown that virulent Mycobacterium tuberculosis H37Rv induces necrosis of infected RAW264 cells at 24 h post infection while avirulent H37Ra and an attenuated H37Rv mutant that is deficient for RD1 region (H37RvDeltaRD1) cause less necrosis of the infected cells. While H37Rv caused damage of the mitochondrial in...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Kaku T,Kawamura I,Uchiyama R,Kurenuma T,Mitsuyama M

    更新日期:2007-09-01 00:00:00

  • Rapid characterization of Mycobacterium fortuitum-chelonei complex by restriction fragment length polymorphism of ribosomal RNA genes.

    abstract::Using labelled, gamma-32P rRNA of mycobacteria as a probe restriction fragment length polymorphism (RFLP) of rRNA genes of strains belonging to the Mycobacterium fortuitum-chelonei complex was analysed. Each DNA sample was cleaved with EcoRI restriction endonuclease, the fragments were separated by agarose gel electro...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Kanaujia GV,Katoch VM,Shivannavar CT,Sharma VD,Patil MA

    更新日期:1991-01-15 00:00:00

  • Expression of putative pathogenicity-related genes in Xylella fastidiosa grown at low and high cell density conditions in vitro.

    abstract::Xylella fastidiosa is the causal agent of economically important plant diseases, including citrus variegated chlorosis and Pierce's disease. Hitherto, there has been no information on the molecular mechanisms controlling X. fastidiosa-plant interactions. To determine whether predicted open reading frames (ORFs) encodi...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Scarpari LM,Lambais MR,Silva DS,Carraro DM,Carrer H

    更新日期:2003-05-16 00:00:00

  • Characterization of a novel plasmid from extremely halophilic Archaea: nucleotide sequence and function analysis.

    abstract::We determined the complete nucleotide sequence of the 16341 bp plasmid pHH205 of the extremely halophilic archaeon Halobacterium salinarum J7. The plasmid has a G+C content of 61.1%. A number of direct and inverted repeat sequences were found in pHH205, while no insertion sequences were found. Thirty-eight large open ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Ye X,Ou J,Ni L,Shi W,Shen P

    更新日期:2003-04-11 00:00:00

  • STa-induced translocation of protein kinase C from cytosol to membrane in rat enterocytes.

    abstract::Escherichia coli heat stable enterotoxin (STa) binds to isolated rat intestinal epithelial cells and triggers a cascade reaction including increase of intracellular calcium levels ([Ca(2+)](i)) and membrane bound protein kinase C (PKC) activity. In response to STa, the cytosolic PKC activity falls from 110 to 35 nmol ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Ganguly U,Chaudhury AG,Basu A,Sen PC

    更新日期:2001-10-16 00:00:00

  • Sucrose accumulation in salt-stressed cells of agp gene deletion-mutant in cyanobacterium Synechocystis sp PCC 6803.

    abstract::The agp gene encoding the ADP-glucose pyrophosphorylase is involved in cyanobacterial glycogen synthesis and glucosylglycerol formation. By in vitro DNA recombination technology, a mutant with partial deletion of agp gene in the cyanobacterium Synechocystis sp. PCC 6803 was constructed. This mutant could not synthesiz...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Miao X,Wu Q,Wu G,Zhao N

    更新日期:2003-01-21 00:00:00

  • Correlation between cell-associated mannose-sensitive hemagglutination by Vibrio parahaemolyticus and adherence to a human colonic cell line Caco-2.

    abstract::Cell-associated hemagglutination (cHA) activity with human erythrocytes was examined for 468 clinical and 71 environmental strains of Vibrio parahaemolyticus. Approximately 95% of the strains tested were cHA positive irrespective of source or Kanagawa phenomenon. 75% of clinical strains showed relatively strong mannos...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Nagayama K,Oguchi T,Arita M,Honda T

    更新日期:1994-07-01 00:00:00

  • Functional analysis of the agnH gene involved in nicotine-degradation pathways in Agrobacterium tumefaciens strain SCUEC1.

    abstract::Agrobacterium tumefaciens strain SCUEC1 is a nicotine-degrading bacterium, which has been recently isolated from the tobacco waste-contaminated field soil. However, the mechanism for nicotine degradation in this strain remains unclear. Here, we analyze the function and biological properties of the agnH gene in the str...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Xia Z,Yu M,Yao J,Feng Z,Li D,Liu T,Cheng G,He D,Li X

    更新日期:2020-02-01 00:00:00

  • Nitrogen status modulates the expression of RNA-binding proteins in cyanobacteria.

    abstract::Biochemical responses to cold and osmotic stresses overlap because each decreases the availability of free water. Since RNA-binding proteins are known to accumulate following cold stress and play key roles in regulating transcription termination, the effect of osmotic stress on expression of RNA-binding proteins was e...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Mori S,Castoreno A,Mulligan ME,Lammers PJ

    更新日期:2003-10-24 00:00:00

  • Analysis of the regulatory region of the lysC gene of Escherichia coli.

    abstract::A lysC-lac'Z fusion plasmid was constructed to study the regulatory region of the lysC gene. Analysis by deletion mutations confirmed the existence of an alternative promoter, P2, located upstream of the previously identified promoter, P1. The transcription start site of promoter P2 was located 85 base pairs upstream ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Liao HH,Hseu TH

    更新日期:1998-11-01 00:00:00

  • Identification Leptospira santarosai serovar shermani specific sequences by suppression subtractive hybridization.

    abstract::In Taiwan, leptospirosis is caused mainly by Leptospira santarosai serovar shermani. Suppression subtractive hybridization was employed to isolate DNA fragments present in pathogenic L. santarosai serovar shermani but absent in non-pathogenic L. biflexa serovar patoc. Analysis of 23 subtracted DNA clones revealed 25 g...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Hsieh WJ,Pan MJ

    更新日期:2004-06-01 00:00:00

  • A plasmid-encoded class 1 integron carrying sat, a putative phosphoserine phosphatase gene and aadA2 from enterotoxigenic Escherichia coli O159 isolated in Japan.

    abstract::A class 1 integron was detected in a single multidrug-resistant strain of enterotoxigenice Escherichia coli (ETEC) O159 after examination of 23 clinical E. coli isolates. This isolate was resistant to streptomycin, kanamycin, gentamicin, chloramphenicol and ampicillin. Sequencing of the class 1 integron identified thr...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Ahmed AM,Shimamoto T

    更新日期:2004-06-15 00:00:00

  • Programmed cell death and the pathogenesis of tissue injury induced by type A Francisella tularensis.

    abstract::Francisella tularensis is a highly virulent bacterial species that causes various forms of tularemia in humans. The urgency in understanding the pathogenesis of these diseases has stimulated unprecedented interest in this bacterial species over the past few years. Recent findings underscore a number of important disti...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章,评审


    authors: Parmely MJ,Fischer JL,Pinson DM

    更新日期:2009-11-01 00:00:00

  • Outer membrane proteins of gentamicin induced small colony variants of Pseudomonas aeruginosa.

    abstract::Small colony variants (SCVs) of Pseudomonas aeruginosa NCTC 6750 (WT) were repeatedly isolated in an in vitro kinetic model after exposure to gentamicin (GM). There were minor differences biochemically and in phage and serotyping between the wild type (WT) strain and SCVs. Changes in outer membrane protein profiles we...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Langford PR,Anwar H,Gonda I,Brown MR

    更新日期:1989-10-01 00:00:00

  • Cell surface characteristics of nontypeable isolates of Streptococcus suis.

    abstract::Streptococcus suis is a worldwide cause of various swine infections and is also an important agent of zoonosis. Strains of S. suis are classified according to their serotype, and currently, 35 serotypes are recognized. The aim of this study was to characterize nontypeable isolates of S. suis with regard to their cell ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Bonifait L,Gottschalk M,Grenier D

    更新日期:2010-10-01 00:00:00

  • Comparison of five rep-PCR genomic fingerprinting methods for differentiation of fecal Escherichia coli from humans, poultry and wild birds.

    abstract::The development of a methodology to identify the origin of fecal pollution is important both for assessing the degree of risk posed to public health and for developing strategies to mitigate the environmental loading of pathogens associated with waterborne disease transmission. Five rep-PCR genomic fingerprinting meth...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Mohapatra BR,Broersma K,Mazumder A

    更新日期:2007-12-01 00:00:00

  • Mutational analysis of the role of the conserved lysine-270 in the Pichia stipitis xylose reductase.

    abstract::Xylose reductase catalyzes the NAD(P)H-dependent reduction of xylose to xylitol and is essential for growth on xylose by yeasts. To understand the nature of coenzyme binding to the Pichia stipitis xylose reductase, we investigated the role of the strictly conserved Lys270 in the putative IPKS coenzyme binding motif by...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Kostrzynska M,Sopher CR,Lee H

    更新日期:1998-02-01 00:00:00

  • A novel colorimetric method for the detection of Escherichia coli using cytochrome c peroxidase-encoding bacteriophage.

    abstract::A new rapid and simple method was developed for the detection of Escherichia coli by constructing a recombinant T4 phage carrying the cytochrome c peroxidase gene derived from Saccharomyces cerevisiae (T4ccp) using which, the colorimetric detection of E. coli K12 was examined. The oxidation activity toward the chromog...

    journal_title:FEMS microbiology letters

    pub_type: 信件


    authors: Hoang HA,Abe M,Nakasaki K

    更新日期:2014-03-01 00:00:00

  • Characterization of Vibrio vulnificus isolated from cockles (Anadara granosa): antimicrobial resistance, plasmid profiles and random amplification of polymorphic DNA analysis.

    abstract::Antibiotic susceptibility, plasmid profiles and random amplification of polymorphic DNA (RAPD) were used to study strains of Vibrio vulnificus isolated from cockles (Anadara granosa). Thirty-six isolates were analyzed. The prevalent biotypes were 1 (72.2% of the isolates) and 2 (27.8%). Among these, 21 strains of biot...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Radu S,Elhadi N,Hassan Z,Rusul G,Lihan S,Fifadara N,Yuherman,Purwati E

    更新日期:1998-08-01 00:00:00

  • Interactions between Bacillus subtilis early spore coat morphogenetic proteins.

    abstract::When challenged by stresses such as starvation, the soil bacterium Bacillus subtilis produces an endospore surrounded by a proteinaceous coat composed of >70 proteins that are organized into three main layers: an amorphous undercoat, lightly staining lamellar inner coat and electron-dense outer coat. This coat protect...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Müllerová D,Krajčíková D,Barák I

    更新日期:2009-10-01 00:00:00

  • Efflux system overexpression and decreased OprD contribute to the carbapenem heterogeneity in Pseudomonas aeruginosa.

    abstract::Pseudomonas aeruginosa strains exhibiting a heterogeneous mode of growth against carbapenems have been described recently. This study investigated the underlying molecular mechanisms in four genetically unrelated P. aeruginosa clinical isolates that were previously characterized by population analyses as heterogeneous...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Ikonomidis A,Tsakris A,Kantzanou M,Spanakis N,Maniatis AN,Pournaras S

    更新日期:2008-02-01 00:00:00

  • Isozyme and morphological characteristics of the anaerobic fungus Piromyces mae isolated from the duodenum, rumen and faeces of sheep.

    abstract::Isolates of anaerobic fungi obtained from the rumen, duodenum and faeces of sheep were identified as Piromyces mae based on their morphological characteristics observed using light microscopy. There was no significant morphological variation among the isolates of P. mae from the rumen, duodenum and faeces. Isozymes of...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Wong MV,Ho YW,Tan SG,Abdullah N,Jalaludin S

    更新日期:1995-12-01 00:00:00

  • The activity of bacteriocins from Carnobacterium maltaromaticum UAL307 against gram-negative bacteria in combination with EDTA treatment.

    abstract::Bacteriocins from gram-positive bacteria are potent antimicrobial peptides that inhibit pathogenic and food-spoilage bacteria. They are usually ineffective against gram-negative bacteria because they cannot penetrate the outer membrane (OM). Disruption of the OM of some gram-negative bacteria was reported to sensitize...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Martin-Visscher LA,Yoganathan S,Sit CS,Lohans CT,Vederas JC

    更新日期:2011-04-01 00:00:00

  • Description of Sulfitobacter sediminilitoris sp. nov., isolated from a tidal flat.

    abstract::A Gram-stain-negative bacterial strain, JBTF-M27T, was isolated from a tidal flat from Yellow Sea, Republic of Korea. Neighbor-joining phylogenetic tree of 16S rRNA gene sequences showed that strain JBTF-M27T fell within the clade comprising the type strains of Sulfitobacter species. Strain JBTF-M27T exhibited the hig...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Park S,Chen S,Lee JS,Kim W,Yoon JH

    更新日期:2020-05-01 00:00:00

  • Bacteria associated with arbuscular mycorrhizal fungi within roots of plants growing in a soil highly contaminated with aliphatic and aromatic petroleum hydrocarbons.

    abstract::Arbuscular mycorrhizal fungi (AMF) belong to phylum Glomeromycota, an early divergent fungal lineage forming symbiosis with plant roots. Many reports have documented that bacteria are intimately associated with AMF mycelia in the soil. However, the role of these bacteria remains unclear and their diversity within intr...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Iffis B,St-Arnaud M,Hijri M

    更新日期:2014-09-01 00:00:00

  • Construction of a family of lactococcal vectors for gene cloning and translational fusion.

    abstract::A family of stable lactococcal vectors have been constructed based on the pFX1 replicon using either the alpha fragment or the complete Escherichia coli lacZ gene as a selective marker. These vectors also incorporate multiple cloning sites and examples are given of their use for gene cloning and translational fusion s...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Xu FF,Pearce LE,Yu PL

    更新日期:1991-01-01 00:00:00