The Salmonella typhimurium flgM gene, which encodes a negative regulator of flagella synthesis and is involved in virulence, is present and functional in other Salmonella species.


:FlgM inhibits the flagella-specific sigma factor FliA and is involved in the mouse-virulence of Salmonella typhimurium. In recent experiments, we observed that: (i) a flgM gene that could function to negatively regulate flagella synthesis was present in a variety of salmonellae; and (ii) the flgM gene derived from Salmonella species that are not normally virulent in mice could complement the S. typhimurium flgM mutant for virulence. Our results suggest that a functional flgM has been retained in most, and perhaps all, Salmonella species, regardless of the motility or virulence phenotype of the strain.


FEMS Microbiol Lett


Schmitt CK,Darnell SC,O'Brien AD




Has Abstract


1996-01-15 00:00:00












  • Incorporation of choline into Streptococcus pneumoniae cell wall antigens: evidence for choline kinase activity.

    abstract::The choline-containing teichoic and lipoteichoic acids play an important part in cell wall metabolism of Streptococcus pneumoniae. We propose that a choline kinase enzyme has a role in the synthesis of these antigens. The presence of this enzyme was demonstrated in cell free extracts of S. pneumoniae by measuring the ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Whiting GC,Gillespie SH

    更新日期:1996-05-01 00:00:00

  • Energy production and peptidase activity in Eikenella corrodens.

    abstract::Eikenella corrodens 33EK(L), a clinical isolate, was assayed for its ability to utilise amino acids as substrates in the reduction of nitrate to nitrite. The metabolism of proline, glutamate, serine and glutamine was found to result in relatively high rates of nitrate reduction. The ability of cells to metabolise thes...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Gully NJ,Rogers AH

    更新日期:1996-06-01 00:00:00

  • Genetic and antigenic comparison of Streptococcus mutans fructosyltransferase and glucan-binding protein.

    abstract::The genes for fructosyltransferase (ftf) and glucan-binding protein (gbp) of Streptococcus mutans strain Ingbritt have been cloned in E. coli using bacteriophage and plasmid vectors. A single ftf gene appears to be responsible for the appearance of several FTF of different electrophoretic mobilities. Despite the fact ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Aduse-Opoku J,Gilpin ML,Russell RR

    更新日期:1989-06-01 00:00:00

  • Antibacterial effects of protruding and recessed shark skin micropatterned surfaces of polyacrylate plate with a shallow groove.

    abstract::Antibacterial effects in terms of biofilm formation and swarming motility were studied using polyacrylate plates having protruding or recessed shark skin micropatterned surfaces with a shallow groove (2 μm pattern width and spacing, 0.4 μm pattern height). It was found that biofilm formation and swarming motility of P...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Sakamoto A,Terui Y,Horie C,Fukui T,Masuzawa T,Sugawara S,Shigeta K,Shigeta T,Igarashi K,Kashiwagi K

    更新日期:2014-12-01 00:00:00

  • Laboratory-acquired lethal infections by potential bioweapons pathogens including Ebola in 2014.

    abstract::Researchers studying both cellular and viral disease agents in the laboratory have become infected since the early days of microbiology 150 years ago. However, in the early 21st century, new concerns about bioweapons being used to generate terror and also with a series of newly emerging or newly understood disease-cau...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章,评审


    authors: Silver S

    更新日期:2015-01-01 00:00:00

  • Biogenic amines in wines: role of lactic acid bacteria.

    abstract::Biogenic amines have undesirable physiological effects when absorbed at too high a concentration. Several kinds of food and beverages contain biogenic amines. Lactic acid bacteria can decarboxylate amino acids. Since winemaking involves the growth of lactic acid bacteria for malolactic fermentation, biogenic amines ma...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章,评审


    authors: Lonvaud-Funel A

    更新日期:2001-05-15 00:00:00

  • Antifungal activity of a novel endochitinase gene (chit36) from Trichoderma harzianum Rifai TM.

    abstract::A novel 36-kDa endochitinase named chit36 has been isolated and characterized from Trichoderma harzianum Rifai TM. Partial amino acid sequences from the purified protein were used to clone the fungal cDNA, based on polymerase chain reaction with degenerate primers. The complete open reading frame encodes a 344-amino a...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Viterbo A,Haran S,Friesem D,Ramot O,Chet I

    更新日期:2001-06-25 00:00:00

  • Proteomics and the stressful life of lactobacilli.

    abstract::Lactobacilli occupy specific ecological niches, where they represent a major component of foods, human and animal microbial communities. Employing these bacteria in industrial fermentations or for human health benefits exposes them to certain life-threatening conditions where their ability to adapt plays a key role in...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章,评审


    authors: Hussain MA,Hosseini Nezhad M,Sheng Y,Amoafo O

    更新日期:2013-12-01 00:00:00

  • Massive Open Online Courses: what will be their legacy?

    abstract::Massive Open Online Courses (MOOCs) dominated discussions of online learning and higher education in the news media and in universities between 2012 and 2015. However, fashions pass, needs change and technology evolves. This Commentary looks back, pauses on the present, and then looks forward. Whilst MOOCs are a signi...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Daniel J

    更新日期:2016-04-01 00:00:00

  • Molecular cloning of a novel allele of SMR1 which determines sulfometuron methyl resistance in Saccharomyces cerevisiae.

    abstract::A different mutation (SMR1B) to SMR1-410 (ilv2), which determines resistance to sulfometuron methyl in Saccharomyces cerevisiae, was cloned by PCR. Sequence analysis indicated a C to T change at position 575 of the ILV2 coding sequence, which results in a proline transition to leucine at position 192. Similarly to SMR...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Xie Q,Jiménez A

    更新日期:1996-04-01 00:00:00

  • Purification and characteristics of cytosolic chitinase from Piromyces communis OTS1.

    abstract::A chitinase was purified from the cytosolic fraction of the anaerobic rumen fungus Piromyces communis OTS1 by affinity chromatography using regenerated chitin, gel filtration and chromatofocusing. The chitinase was most active at pH 6.2 and at 60 degrees C in a 20-min assay. The molecular mass of the purified protein ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Sakurada M,Morgavi DP,Komatani K,Tomita Y,Onodera R

    更新日期:1996-03-15 00:00:00

  • Bacterial degradation of natural rubber: a privilege of actinomycetes?

    abstract::Using natural rubber latex as the sole source of carbon and energy 50 rubber-degrading bacteria were isolated. Out of those 50 isolates, 33 were identified as Streptomyces species and 8 as Micromonospora species. Screening of 1220 bacteria obtained from different culture collections revealed 46 additional rubber-degra...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Jendrossek D,Tomasi G,Kroppenstedt RM

    更新日期:1997-05-15 00:00:00

  • A combined stress response analysis of Spirulina platensis in terms of global differentially expressed proteins, and mRNA levels and stability of fatty acid biosynthesis genes.

    abstract::Changes in gene expression play a critical role in enhancing the ability of cyanobacteria to survive under cold conditions. In the present study, Spirulina platensis cultures were grown at the optimal growth temperature, in the light, before being transferred to dark conditions at 22 degrees C. Two dimensional-differe...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Jeamton W,Mungpakdee S,Sirijuntarut M,Prommeenate P,Cheevadhanarak S,Tanticharoen M,Hongsthong A

    更新日期:2008-04-01 00:00:00

  • Crystalline 3-methylaspartase from a facultative anaerobe, Escherichia coli strain YG1002.

    abstract::Crystalline 3-methylaspartase (EC from Escherichia coli strain YG1002 that had been isolated from soil was characterized. The enzyme activity was induced when the organism was grown statically on medium containing (S)-glutamic acid. Its molecular mass is about 84 kDa, and it may be composed of two identical s...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Asano Y,Kato Y

    更新日期:1994-05-15 00:00:00

  • Heat-inactivation of plasmid-encoded CI857 repressor induces gene expression from Ind- lambda prophage in recombinant Escherichia coli.

    abstract::We have observed significant cell lysis upon temperature up-shift of recombinant Escherichia coli cultures harboring CI857-repressed lambda-based expression vectors. This event, that becomes evident about 30-40 min after the heat shock, takes place when using the lambda promoter system in Ind- lysogenic strains, but n...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Hoffmann F,Arís A,Carbonell X,Rohde M,Corchero JL,Rinas U,Villaverde A

    更新日期:1999-08-15 00:00:00

  • Occurrence of aminoglycoside-modifying enzymes among isolates of Escherichia coli exhibiting high levels of aminoglycoside resistance isolated from Korean cattle farms.

    abstract::This study investigated 247 Escherichia coli isolates collected from four cattle farms to characterize aminoglycoside-modifying enzyme (AME) genes, their plasmid replicons and transferability. Out of 247 isolates a high number of isolates (total 202; 81.78%) were found to be resistant to various antibiotics by disc di...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Belaynehe KM,Shin SW,Hong-Tae P,Yoo HS

    更新日期:2017-08-01 00:00:00

  • Characterization of a replication locus and formation of a higher-order complex between RepA protein and two inverted repeats in Streptomyces plasmid pSV1.

    abstract::We identified the minimal locus of 163-kb plasmid pSV1 of Streptomyces violaceoruber for the replication in S. lividans. This locus comprised a repA gene and an upstream 407-bp sequence containing two inverted repeats (IR-III and IR-IV) within an iteron, an AT-rich region and a 300-bp noncoding sequence (NCS). RepA pr...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Chen Y,Tan H,Qin Z

    更新日期:2013-12-01 00:00:00

  • High catalytic activity of alanine racemase from psychrophilic Bacillus psychrosaccharolyticus at high temperatures in the presence of pyridoxal 5'-phosphate.

    abstract::We examined the effect of the pyridoxal 5'-phosphate (PLP) cofactor on the activity and stability of the psychrophilic alanine racemase, having a high catalytic activity at low temperature, from Bacillus psychrosaccharolyticus at high temperatures. The decrease in the enzyme activity at incubation temperatures over 40...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Okubo Y,Yokoigawa K,Esaki N,Soda K,Misono H

    更新日期:2000-11-15 00:00:00

  • Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and S. mutans.

    abstract::In the dental caries pathogen Streptococcus mutans, an MarR-like transcriptional regulator (RcrR), two ABC efflux pumps (RcrPQ) and two effector peptides encoded in the rcrRPQ operon provide molecular connections between stress tolerance, (p)ppGpp metabolism and genetic competence. Here, we examined the role of RcrRPQ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Shields RC,Burne RA

    更新日期:2015-08-01 00:00:00

  • Surface Listeria monocytogenes carbohydrate-binding components revealed by agglutination with neoglycoproteins.

    abstract::Carbohydrate-binding components were shown to be present at the surface of Listeria monocytogenes by means of a panel of neoglycoproteins using direct agglutination. These lectin-like components bind on neoglycoproteins bearing D-glucosamine, L-fucosylamine, or para-amino-phenyl-alpha-D-mannopyrannoside residues. The ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Cottin J,Loiseau O,Robert R,Mahaza C,Carbonnelle B,Senet JM

    更新日期:1990-03-15 00:00:00

  • A species of magnetotactic deltaproteobacterium was detected at the highest abundance during an algal bloom.

    abstract::Magnetotactic bacteria (MTB) are a group of microorganisms that have the ability to synthesize intracellular magnetic crystals (magnetosomes). They prefer microaerobic or anaerobic aquatic sediments. Thus, there is growing interest in their ecological roles in various habitats. In this study we found co-occurrence of ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Pan H,Dong Y,Teng Z,Li J,Zhang W,Xiao T,Wu LF

    更新日期:2019-11-01 00:00:00

  • Characterization of DegU-dependent expression of bpr in Bacillus subtilis.

    abstract::The response regulator DegU and its cognate histidine kinase DegS constitute a two-component system in the Gram-positive soil bacterium Bacillus subtilis. The phosphorylated form of DegU is known to activate transcription of more than 120 genes in B. subtilis, including the bpr gene encoding bacillopeptidase F. To cha...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Tsukahara K,Ogura M

    更新日期:2008-03-01 00:00:00

  • Genetic evidence for a novel thymidylate synthase in the halophilic archaeon Halobacterium salinarum and in Campylobacter jejuni.

    abstract::A search of the complete genome sequence of the halophilic archaeon Halobacterium salinarum failed to identify a gene homologous to the thymidylate synthase (thyA) gene present in the closely related Haloferax volcanii. To understand the source of thymidine synthesis in Hbt. salinarum, a genomic library of Hbt. salina...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Giladi M,Bitan-Banin G,Mevarech M,Ortenberg R

    更新日期:2002-10-29 00:00:00

  • Truepera radiovictrix gen. nov., sp. nov., a new radiation resistant species and the proposal of Trueperaceae fam. nov.

    abstract::Two isolates, belonging to a new species of a novel genus of the Phylum "Deinococcus/Thermus ", were recovered from hot spring runoffs on the Island of São Miguel in the Azores. Strains RQ-24(T) and TU-8 are the first cultured representatives of a distinct phylogenetic lineage within this phylum. These strains form or...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Albuquerque L,Simões C,Nobre MF,Pino NM,Battista JR,Silva MT,Rainey FA,da Costa MS

    更新日期:2005-06-15 00:00:00

  • In vitro assay for the Bacillus subtilis signal peptidase SipS: systems for efficient in vitro transcription-translation and processing of precursors of secreted proteins.

    abstract::The signal peptidase (SPase) SipS of Bacillus subtilis is responsible for the processing of precursors of secreted proteins. It differs from the SPases of Gram-negative bacteria in structure and specificity. To assay the activity of SipS in vitro, two efficient transcription-translation systems for the synthesis of ra...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Vehmaanperä J,Görner A,Venema G,Bron S,van Dijl JM

    更新日期:1993-12-01 00:00:00

  • Draft genome sequence of the Chilean isolate Aeromonas salmonicida strain CBA100.

    abstract::We report the draft genome sequence from Aeromonas salmonicida sp. strain CBA100, which was characterized as an antibiotic-resistant bacterium isolated from infected rainbow trout. The total size of the genome is 4,788,109 bp, with a G + C content of 60.55%. Comparison of its open reading frames shows that the closest...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Valdes N,Espinoza C,Sanhueza L,Gonzalez A,Corsini G,Tello M

    更新日期:2015-03-01 00:00:00

  • Comparative study of two typing methods, hsp65 PRA and ITS sequencing, revealed a possible evolutionary link between Mycobacterium kansasii type I and II isolates.

    abstract::One hundred and ninety-eight clinical isolates of Mycobacterium kansasii collected between 2003 and 2004 in Japan were genotyped by PCR and restriction enzyme analysis (PRA) and 16S-23S internal transcribed spacer (ITS) sequencing. The results demonstrated that clinical isolates of M. kansasii in Japan are almost excl...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Iwamoto T,Saito H

    更新日期:2006-01-01 00:00:00

  • Astaxanthin formation in the marine photosynthetic bacterium Rhodovulum sulfidophilum expressing crtI, crtY, crtW and crtZ.

    abstract::This study reports the production of astaxanthin in the photosynthetic bacterium Rhodovulum sulfidophilum, which has adequate precursor pools and storage capabilities for heterologous carotenoid production. Chemical mutagenesis was carried out using ethylmethane sulfonate to produce mutants with a modified carotenoid ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Mukoyama D,Takeyama H,Kondo Y,Matsunaga T

    更新日期:2006-12-01 00:00:00

  • Specific interaction of the protein-D2 porin of Pseudomonas aeruginosa with antibiotics.

    abstract::The protein-D2 porin of Pseudomonas aeruginosa is lacking in carbapenem or fluoroquinolone-resistant strains and hence was thought to facilitate the diffusion of these antibiotics. We examined the effect of several antibiotics on the single channel conductivity of protein-D2 in planar lipid bilayers and found that flu...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Ishii J,Nakae T

    更新日期:1996-02-01 00:00:00

  • Restricted growth of ent(-) and tonB mutants of Salmonella enterica serovar Typhi in human Mono Mac 6 monocytic cells.

    abstract::Monocytes and macrophages are an important host defense in humans infected with Salmonella enterica serovar Typhi. Bacterial ability to survive in these cells is therefore a crucial virulence characteristic of this pathogen. In this study, we demonstrate that growth of a Salmonella enterica serovar Typhi enterochelin ...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Gorbacheva VY,Faundez G,Godfrey HP,Cabello FC

    更新日期:2001-03-01 00:00:00