Fos induction in brainstem neurons by intravenous hypertonic saline in the conscious rat.

Abstract:

:Experiments were done in conscious rats to investigate the effect of intravenous infusion of hypertonic saline on the induction of the protein Fos, in brainstem neurons. Neurons containing Fos-like immunoreactivity were observed in the caudal nucleus of the solitary tract (NTS), the caudal and rostral ventrolateral medulla, and parabrachial nucleus after an infusion of solutions containing 1.4 M NaCl. Little or no expression of Fos was detected in brainstem neurons after intravenous infusions of either physiological (143 mM) or hypotonic (106 mM) NaCl solutions. These data provide evidence for the involvement of brainstem structures in osmoregulatory functions and suggest that brainstem neuronal circuits that function in cardiovascular regulation may also be shared by those involved in body fluid homeostasis.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Hochstenbach SL,Solano-Flores LP,Ciriello J

doi

10.1016/0304-3940(93)90270-u

subject

Has Abstract

pub_date

1993-08-20 00:00:00

pages

225-8

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(93)90270-U

journal_volume

158

pub_type

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