Abstract:
:Acrylonitrile (AN) showed spectral interaction with hepatic microsomes from mouse, rat and man. Whereas human and rat liver microsomes resulted in ligand AN-binding spectra, mouse liver microsomes behaved differently. Hepatic microsomes from phenobarbital-treated mice with AN showed a type I substrate binding; ligand spectra are recorded with microsomes from benzo[a]pyrene-treated mice. Microsomes from untreated control mice showed a mixed type behaviour.
journal_name
Toxicol Lettjournal_title
Toxicology lettersauthors
Appel KE,Peter H,Bolt M,Bolt HMdoi
10.1016/0378-4274(81)90057-6subject
Has Abstractpub_date
1981-02-01 00:00:00pages
335-9issue
4-5eissn
0378-4274issn
1879-3169pii
0378-4274(81)90057-6journal_volume
7pub_type
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