Abstract:
:An enzyme immunoassay (EIA) was developed in which nuclear extracts were bound to the wells of polystyrene microtiter plates. The presence of various antigens in the extracts could be detected using antiserum raised against HeLa cell nucleoli. Normal human cell extracts, coupled to Sepharose as a solid phase absorbent, were used to remove antibodies directed against antigens present in normal cells, The resulting purified antibodies produced a linear EIA absorbance in the range of 100-500 ng tumor extract, but little EIA absorbance with nuclear extracts from human placenta and liver.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Kelsey DE,Busch RK,Busch Hdoi
10.1016/0304-3835(81)90171-3subject
Has Abstractpub_date
1981-05-01 00:00:00pages
295-303issue
4eissn
0304-3835issn
1872-7980pii
0304-3835(81)90171-3journal_volume
12pub_type
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