Expression of the inhibitor of apoptosis protein survivin in benign meningiomas.

Abstract:

:Survivin is a recently characterised inhibitor of apoptosis protein that has been implicated in the pathogenesis of several types of solid organ cancer. This study sought to describe the expression of survivin in a cohort of 90 benign meningiomas, together with the pattern of expression of other genes involved in the apoptotic process, namely bax and bcl2. Survivin expression was noted in 94% (85/90) of samples and was not correlated with the expression of either bax or bcl2 or with clinicopathological factors.

journal_name

Cancer Lett

journal_title

Cancer letters

authors

Das A,Tan WL,Smith DR

doi

10.1016/s0304-3835(02)00741-3

keywords:

subject

Has Abstract

pub_date

2003-04-25 00:00:00

pages

217-23

issue

2

eissn

0304-3835

issn

1872-7980

pii

S0304383502007413

journal_volume

193

pub_type

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