Abstract:
:Estrogen (ER) - and progestagen (PgR) - receptors were estimated by a DCC method using Scatchard plot analysis In tissue samples of 68 patients with ovarian carcinomas. The mean ER and PgR levels were at 52 and 74 fmol/mg cytosol protein, respectively. ER+ PgR+ records were noted in 32.4%, ER+ PgR- in 26.4%, ER- PgR+ in 7.4%, and 33.8% presented with ER- PgR-. In the surviving group 44.1% had Er+ PgR+, whereas the patients who died had an incidence of only 20.5% ER+ PgR+. In addition, the incidences of ER+ PgR+ in stage I plus II and stage III plus IV patients were 42.6 and 29.5%, respectively. Furthermore, higher incidences of ER+ PgR+ were recorded in patients older than 60 years of age (63%) than in younger subjects (36%). The present data combine to suggest that receptor assays should become a useful tool in the management of patients bearing ovarian carcinomas. In addition, ER and PgR determinations provide a prognostic index and may improve the possibility to predict which well-differentiated stage I ovarian carcinomas are likely to recur.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Spona J,Gitsch E,Salzer H,Karrer Kdoi
10.1159/000299256subject
Has Abstractpub_date
1983-01-01 00:00:00pages
189-98issue
4eissn
0378-7346issn
1423-002Xjournal_volume
16pub_type
杂志文章abstract:AIM:We investigated whether there is a correlation between morphological changes of the lower uterine segment after caesarean section (CS), visualized by means of either a transvaginal sonography (TVS) or a sonohysterography (SHG), and the frequency of abnormal uterine bleedings reported by the women. METHODS:By means...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000091497
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/AIMS:Perinatal environmental exposure may affect fetal development and reprogram the developing organism for adult-onset disease. In this case-control study, we aimed at assessing this pathogenetic model in endometriosis. METHODS:Consecutive patients with a first laparoscopic diagnosis of endometriosis were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000323531
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Carcinoma-associated Tn and sialyl-Tn antigens have been shown to aid in the prediction of tumor aggressiveness. The purpose of this study was to evaluate the prognostic value of Tn and sialyl-Tn antigen expression in human ovarian carcinoma. METHODS:Formalin-fixed, paraffin-embedded tissue sections from 32 ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292284
更新日期:1996-01-01 00:00:00
abstract::A dietary approach has proven to be effective in alleviating symptoms of premenstrual syndrome. In our previous studies, magnesium improved premenstrual irritability and mood scoings. In this double-blind, placebo-controlled study, we evaluated the effects of a new dietetic preparation (Sillix Donna, Giuliani) in 40 p...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000291836
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of depot medroxy progesterone acetate (DMPA) as a preparatory agent for endometrial resection. STUDY DESIGN:Endometrial resection was performed on 50 women for excessive uterine bleeding. The patients were randomly divided into 2 equal groups, with the first group receiving DMPA and ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000052969
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/AIMS:To review the literature and compare detection rates, false negative (FN) rates, and negative predictive values (NPVs) of sentinel lymph node (SLN) biopsy in endometrial cancer to those in breast and vulvar cancer. Secondary objectives were to evaluate techniques of SLN biopsy in endometrial cancer. ME...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000353897
更新日期:2013-01-01 00:00:00
abstract::In a prospective clinical investigation of 2,144 deliveries, we elucidate the indications for episiotomy and how different methods of anesthesia affect the frequency of episiotomy and the perineal problems after episiotomy compared with those after spontaneous perineal laceration. We found a significantly higher infec...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293161
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:Some embryo implantation problems in patients with recurrent implantation failure may be explained by the inability of the embryo to hatch out of its zona pellucida. In this case-control study, a study group which had received modified quarter laser-assisted zona thinning (mQLAZT) was compared with a co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000171068
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Maternal risk factors may interfere with mechanisms regulating fetal growth. The aim of the present study was to determine which sociodemographic and reproductive risk factors may be related to fetal growth restriction (FGR), with a special focus on determinants possible for preventive intervention. MATER...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000314020
更新日期:2010-01-01 00:00:00
abstract::Amniotic fluids from women in West Virginia were evaluated for the presence of antibacterial activity by a bioassay technique. 41% of 32 third trimester samples were inhibitory. Evaluation of additional test organisms emphasized differences in susceptibility of various bacterial strains; two isolates of Escherichia co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299390
更新日期:1983-01-01 00:00:00
abstract::To evaluate a new reflectance photometer (Accusport) for blood lactate determination, a prospective non-interventional study was performed on blood obtained from the umbilical cord artery immediately after delivery of the baby in 109 consecutive women. For each sample, the results of cord arterial blood lactate values...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009919
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:To determine whether genetic alterations in the CD9 gene are associated with female infertility in humans. METHODS:We sequenced the entire coding region of this gene in 86 Japanese women with unexplained infertility and further conducted a case-control study of six tagging single nucleotide polymorphis...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000262451
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:The purpose of this study was to determine the relationship between maternal characteristics and severe postpartum hemorrhage (PPH). METHODS:Medical records of women who delivered at Duke University Hospital between 2001 and 2004 with an ICD-9 code for PPH were reviewed. Women with PPH who received blo...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000329335
更新日期:2012-01-01 00:00:00
abstract::As part of a case control within cohort study 472 pregnant women answered a questionnaire post partum. Serum relaxin concentrations were measured by a homologous ELISA in samples collected from the women in the 30th week of pregnancy. Serum relaxin concentrations were not associated with pregnancy-associated pelvic pa...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292438
更新日期:1994-01-01 00:00:00
abstract::Human heparanase has been shown to function in tumor progression, metastatic spread, and tumor angiogenesis. The aim of the present study was to assess heparanase expression in endometrial cancer in correlation with neovascularization and clinicopathological factors. Forty endometrial cancers were obtained from previo...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000072821
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Little is known about proper interval periods between the flushings of totally implantable access ports after completion of chemotherapy. Manufacturer guidelines recommend flushing catheters every 4 weeks. METHODS:This retrospective study examined whether flushing less than every 4 weeks conferred any benef...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294919
更新日期:2010-01-01 00:00:00
abstract::Hyaluronan (HA), a high molecular weight polysaccharide, is a major component of connective tissue and is thus present in the extracellular matrix of most tissues. Increased serum concentrations have been reported in association with pre-eclampsia and liver malfunction, amongst other disorders. We have performed histo...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052986
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:We sought to compare the pullout strengths of the sacral end of the sacrocolpopexy mesh when attached using one suture at the first versus second sacral vertebral level (S1 vs. S2) in female cadaveric pelvises. METHODS:The sacral vertebrae were isolated in 9 unembalmed female cadavers, and segments of polyp...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000338892
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Clarifying the normal distribution of activation antigens will contribute to database construction studies of monoclonal-antibody-based therapies in endometrial disorders. METHODS:In this study, endometrial tissue samples obtained during proliferative and secretory phases and decidual samples of early pregn...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092375
更新日期:2006-01-01 00:00:00
abstract::We have previously shown a marked diurnal variation in the excretion of cortisol and 6 beta-hydroxycortisol at 36-38 weeks pregnancy with no variation in estrogen excretion. Since others have shown a reciprocal relationship between plasma levels of estriol and cortisol at 30-35 weeks of pregnancy, we decided to determ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298855
更新日期:1987-01-01 00:00:00
abstract::The study assessed the agreement in cardiotocogram interpretation between the 2CTG computerized system and experienced and inexperienced observers involved in a telecardiotocography project called 'TOCOMAT'. Both observers and computer analyzed FHR baseline, FHR variability, and number of large accelerations and of de...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000068955
更新日期:2003-01-01 00:00:00
abstract::The concentration of collagen in the human uterine cervix decreases during pregnancy. This change contributes to the ripening process, which facilitates cervical dilatation during labor. It has been suggested that cervical collagen is partly degraded at term and after delivery. In order to evaluate this hypothesis we ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298975
更新日期:1985-01-01 00:00:00
abstract::A decade of perinatal audit in the Maputo Central Hospital is reviewed with the objective of addressing the potential value of the audit process in monitoring the different constituents of morbidity and mortality in the perinatal period. The perinatal mortality showed a significant but transient change during the obse...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292637
更新日期:1993-01-01 00:00:00
abstract::Implantation of intrauterine devices (IUDs) is associated with an increased incidence of uterine infection, probably as a result of vaginal bacteria entering the uterus at the time of insertion. To reduce the incidence of IUD-related infections, the incorporation of antimicrobial agents into the tail of the device was...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010256
更新日期:2000-01-01 00:00:00
abstract::The diagnosis of vulvo-vaginal complaints has always been enigmatic in obstetrics and gynecology. Patients with clear, pathognomonic symptoms end up with a proper diagnosis and treatment most of the time, but unfortunately we are now living in a world where women reach out to the Internet and readily get all informati...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000478982
更新日期:2017-01-01 00:00:00
abstract::We immunohistologically studied the hepatic tissue sections in cases with the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome; n = 2) and acute fatty liver of pregnancy (AFLP; n = 2) compared to necropsy controls. Unlike in the AFLP cases, a marked infiltration of neutrophils in liver ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292053
更新日期:1996-01-01 00:00:00
abstract::We experienced a typical case of eclampsia. After the onset of eclampsia, we performed magnetic resonance imaging angiography (MRI angiography) to estimate the function of the cerebral artery. MRI angiography showed that spasm occurred in many cerebral arteries. The spasm was still observed in some arteries 13 day aft...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292595
更新日期:1993-01-01 00:00:00
abstract::The psychology of infertile women was investigated with a battery of psychological tests consisting of a semistructured interview, State Trait Anxiety Inventory (STAI), Center for Epidemiologic Studies Depression Scale (CES-D), and Cornell Medical Index (CMI). The subjects were 107 infertile women being treated for in...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291848
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND/AIMS:Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and well-being. The pathophysiology and epidemiology of fibroids are poorly understood. Obesity and elevated blood pressure have been reported to be predisposing factors. In this study, we investigat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000114250
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To investigate the expression of T-cell immunoglobulin and mucin domain 3 (TIM-3) on peripheral T cells of cervical carcinoma patients. METHODS:Peripheral blood samples from 15 high-grade cervical squamous intraepithelial lesion (HSIL) patients, 24 cervical carcinoma patients, and 21 healthy controls were co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000511440
更新日期:2020-12-04 00:00:00