Abstract:
BACKGROUND:Little is known about proper interval periods between the flushings of totally implantable access ports after completion of chemotherapy. Manufacturer guidelines recommend flushing catheters every 4 weeks. METHODS:This retrospective study examined whether flushing less than every 4 weeks conferred any benefit. RESULTS:349 totally implanted access ports were divided into four groups based on the different durations of the intervals between flushings. Sixteen (4.6%) complications were observed in the study population. CONCLUSION:Our results demonstrate that extending the flushing interval to up to 4 months remains medically safe and drastically reduces the costs.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Ignatov A,Ignatov T,Taran A,Smith B,Costa SD,Bischoff Jdoi
10.1159/000294919subject
Has Abstractpub_date
2010-01-01 00:00:00pages
91-4issue
2eissn
0378-7346issn
1423-002Xpii
000294919journal_volume
70pub_type
杂志文章abstract:BACKGROUND:Cisplatin is used as a key drug for ovarian yolk sac tumor (YST), but relapse may occur. Details of the molecular mechanism responsible for cisplatin resistance remain unclear. METHODS:We established cisplatin-resistant ovarian YST cells (NOY1-CR) from parent NOY1. To characterize these cells, we examined c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000320744
更新日期:2011-01-01 00:00:00
abstract::The ovarian morphology in 149 patients with the clinical syndrome of polycystic ovaries (group I) is described. The ovaries from 10 age-matched women (group II) with no signs of ovarian disorder were investigated as a reference material. The number of cysts documented for group I was twice that of the reference group ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293771
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To determine whether, in addition to treatment with antibiotics, it is necessary to remove the intrauterine device (IUD) to eliminate genital colonization by Actinomyces. METHODS:A randomized clinical trial was carried out. Patients were divided into two groups. The intervention group did not have their IUDs...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000052955
更新日期:2001-01-01 00:00:00
abstract::Our objective was to compare ophthalmic artery pulsatility index values from normal pregnant women with those from preeclampsia patients. The ophthalmic artery of 20 normotensive pregnant women, 7 mildly preeclamptic and 2 severely preeclamptic patients was studied once with color Doppler flow imaging and pulsed Doppl...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292298
更新日期:1995-01-01 00:00:00
abstract:AIMS:To determine the cut-off level of endometrial thickness for detecting endometrial disease on a large scale of screening and to examine the usefulness of transvaginal ultrasonography (TVS) for endometrial disease screening in asymptomatic postmenopausal Japanese women. METHODS:The study involved 1,400 postmenopaus...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000087375
更新日期:2005-01-01 00:00:00
abstract::Estrogen (ER) - and progestagen (PgR) - receptors were estimated by a DCC method using Scatchard plot analysis In tissue samples of 68 patients with ovarian carcinomas. The mean ER and PgR levels were at 52 and 74 fmol/mg cytosol protein, respectively. ER+ PgR+ records were noted in 32.4%, ER+ PgR- in 26.4%, ER- PgR+ ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299256
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND/AIMS:A phase II study was conducted to assess the activity and toxicity of weekly docetaxel in patients with advanced or recurrent cancer of the cervix. METHODS:Eligible patients were required to have measurable disease with adequate performance status, bone marrow, renal and hepatic function. Patients were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000106489
更新日期:2007-01-01 00:00:00
abstract:AIM:To investigate the ability of lactobacilli to persist in the genital area (vagina and labia) of women after the topical application of an ointment containing Lactobacillus gasseri LN40, L. fermentum LN99 and L. rhamnosus LN113. Secondary objectives were to study the presence of Escherichia coli and other contaminan...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000446946
更新日期:2017-01-01 00:00:00
abstract::The measurement of the tissue concentrations of cyclic adenosine monophosphate (cAMP) in human endometrium shows that the levels of the nucleotide vary during the menstrual cycle, being 11.4 +/- (SE) 2.5 and 37.7 +/- (SE) 10.1 pmol/mg protein in the proliferative and secretory phase, respectively. The individual deter...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299076
更新日期:1984-01-01 00:00:00
abstract::Subcutaneous heparin and plasma infusion were successfully used during an induced abortion in a young woman with familial antithrombin-III deficiency and a history of severe thrombotic episodes. :Women with herditary antithrombin-3 deficiency are exposed to a considerable risk of thrombosis during periods of thrombog...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299612
更新日期:1981-01-01 00:00:00
abstract:AIMS:To establish leukocyte count and differential percentiles in healthy singleton term laboring women during spontaneous normal vaginal labor following an uncomplicated pregnancy. METHODS:An analysis of the records of all women (n = 762) who delivered at our delivery ward during a 2-month period was performed. After...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000365084
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND/AIMS:Previous studies on the effects of estrogen on sclerostin regulation were conducted in postmenopausal women in humans or animals following estrogen treatment or induced estrogen deficiency. The aim of this study was to evaluate the effects of sex hormones on serum sclerostin levels in premenopausal wome...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000347013
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) enzymes take part in extracellular matrix (ECM) remodeling which has been shown to contribute to the ovulation and follicular functions. We aimed to compare serum levels of ADAMTS-19 in patients with different fertility situations. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000490665
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:We sought to compare the pullout strengths of the sacral end of the sacrocolpopexy mesh when attached using one suture at the first versus second sacral vertebral level (S1 vs. S2) in female cadaveric pelvises. METHODS:The sacral vertebrae were isolated in 9 unembalmed female cadavers, and segments of polyp...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000338892
更新日期:2012-01-01 00:00:00
abstract::Acupuncture treatment in the final weeks of pregnancy has been claimed to shorten the duration of labor in primiparous women. In the present study, the length of the various phases of labor was calculated for 56 primiparous women who were repeatedly treated with manual acupuncture during the month prior to parturition...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298806
更新日期:1987-01-01 00:00:00
abstract::We herein present a case of exencephaly with rachischisis, situs ambiguous and club feet, diagnosed antenatally by ultrasound. This combination of anomalies is very rare. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293305
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To evaluate whether prolactin, alpha-fetoprotein (AFP) or B-human chorionic gonadotropin (BHCG) is the most effective marker in vaginal fluid for diagnosing prelabor rupture of membranes (PROM). These proteins are present in amniotic and vaginal fluid and have been reported to be potent markers of PROM, but h...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000097844
更新日期:2007-01-01 00:00:00
abstract::Advances in fetal echocardiography enable the prenatal diagnosis of a vast majority of congenital heart defects. On the other hand, ostium secundum atrial septal defect is difficult to diagnose in the fetus. Although a defect of minor clinical significance, this may be the only intrauterine finding of a chromosomal an...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009910
更新日期:1998-01-01 00:00:00
abstract::Penis and testicle amputation, vaginoplasty, and clitoroplasty are procedures that help male-to-female transsexuals to accept their body and to increase psychosocial well-being. We describe a successful correction of prolapse of the neovagina with abdominovaginal sacropexy in a male-to-female transsexual who had under...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000064559
更新日期:2002-01-01 00:00:00
abstract::The study's objective was to determine if using human chorionic gonadotropin (hCG) as a timing method for intrauterine insemination (IUI) in patients who make mature follicles but have cervical factor problems has a negative effect on pregnancy rates (PRs) (possibly by releasing an immature oocyte), or increases the r...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000292447
更新日期:1994-01-01 00:00:00
abstract::Since not all problems in endometriosis can be studied in the human, there is need of an animal model. We transplanted endometrial tissue of the rabbit into the peritoneal cavity and studied the changes after 12 weeks. At that time the endometrial implants in the rabbit had become cystic structures. The macroscopic an...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293611
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:Maternal risk factors may interfere with mechanisms regulating fetal growth. The aim of the present study was to determine which sociodemographic and reproductive risk factors may be related to fetal growth restriction (FGR), with a special focus on determinants possible for preventive intervention. MATER...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000314020
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of this meta-analysis was to determine whether frozen embryo transfer (ET) increases ectopic pregnancy (EP) rate compared with fresh ET. METHODS:A meta-analysis was performed of data from seven comparative studies including 13,059 pregnancies that resulted from nondonor in vitro fertilization c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,meta分析
doi:10.1159/000213048
更新日期:2009-01-01 00:00:00
abstract::To study the effect of calcium and vitamin D supplementation on the incidence of toxaemia of pregnancy, 200 randomly selected pregnant women (supplemented group), were put on calcium (375 mg/day) and vitamin D (1,200 IU/day) supplements at 20-24 weeks of pregnancy onwards. Another 200 pregnant women constituted the no...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000298772
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:Our objective was to evaluate the direct effect of tamoxifen citrate (TAM) on the endometrium, liver, breast tissue and the lipid profile in oophorectomized (OX) rats. STUDY DESIGN:An experimental animal study. MATERIAL AND METHODS:Forty-one mature rats (33 OX) were randomly divided into four groups and rec...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009933
更新日期:1998-01-01 00:00:00
abstract::The electric activity of the ovary was studied in 13 female mongrel dogs aiming at characterizing a normal electro-oophorogram (EOOG). Two monopolar silver-silver chloride electrodes were sutured under anesthesia to the ovary of the bitches which were in the anestrus phase of the estrous cycle. A daily recording sessi...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010012
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND:Genetic factors may play a role in male infertility. METHODS:In a prospective case-control study, we assessed the allele and genotype frequencies of the TNFalpha -308 C-->T and -863 C-->A polymorphisms, detected by PCR of sperm DNA, of 577 Caucasian men recruited in an infertility clinic. Semen sampling was...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000126494
更新日期:2008-01-01 00:00:00
abstract::The identification of immunoreactive beta-endorphin, beta-lipotropin and ACTH from extracts of human placentas by radioimmunoassay suggests a probable synthesis of these peptides in the placenta. In this study we investigated the presence of beta-endorphin and ACTH in placenta, amniotic membranes and umbilical cord us...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299023
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND/AIMS:Some embryo implantation problems in patients with recurrent implantation failure may be explained by the inability of the embryo to hatch out of its zona pellucida. In this case-control study, a study group which had received modified quarter laser-assisted zona thinning (mQLAZT) was compared with a co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000171068
更新日期:2009-01-01 00:00:00
abstract::A defect in placental function has been suggested to be associated both with preeclampsia (PE), with or without concomitant intrauterine growth retardation (IUGR), and with IUGR as a single entity. Our aim was to compare the mRNA expression of the growth-related protooncogenes c-fos and c-jun and the vasoconstrictor a...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291494
更新日期:1997-01-01 00:00:00