Abstract:
BACKGROUND/AIMS:To review the literature and compare detection rates, false negative (FN) rates, and negative predictive values (NPVs) of sentinel lymph node (SLN) biopsy in endometrial cancer to those in breast and vulvar cancer. Secondary objectives were to evaluate techniques of SLN biopsy in endometrial cancer. METHODS:The PubMed database was searched for applicable scientific articles. Detection rates, FN rates, and NPVs were calculated for all studies. Studies were stratified by techniques and compared. RESULTS:Nineteen articles met criteria for this review. The overall detection rates ranged from 62 to 100%, the FN rate ranged from 0 to 50%, and the NPVs ranged from 95 to 100%. There is no technique that is definitively superior to any other with regard to surgical modality, injectant used, injection site, or pathologic techniques. CONCLUSIONS:Studies on SLN biopsy in endometrial cancer have a large range of detection rates and FN rates, and larger studies including more patients with metastatic disease are needed for comparison with breast and vulvar cancers. While no techniques are definitively superior to others, minimally invasive surgery, cervical injection, and pathologic analysis utilizing HE staining, immunohistochemistry, and ultrastaging may be clinically advantageous.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Levinson KL,Escobar PFdoi
10.1159/000353897subject
Has Abstractpub_date
2013-01-01 00:00:00pages
139-50issue
3eissn
0378-7346issn
1423-002Xpii
000353897journal_volume
76pub_type
杂志文章,评审abstract::25 singleton pregnancies were terminated by cesarean section between 28 and 33 weeks of gestation because of suspected growth retardation and abnormal unstressed cardiotocograms. Only infants with birth weights below the tenth centile were considered. 17 survived and were neurologically examined at 2.5-7 years of age....
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299030
更新日期:1985-01-01 00:00:00
abstract::The diagnosis of vulvo-vaginal complaints has always been enigmatic in obstetrics and gynecology. Patients with clear, pathognomonic symptoms end up with a proper diagnosis and treatment most of the time, but unfortunately we are now living in a world where women reach out to the Internet and readily get all informati...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000478982
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To compare the maternal and perinatal outcome of nulliparous women 35 years and older at the time of delivery with nulliparous women 25-29 years old. METHODS:A retrospective review of maternal and newborn records of singleton gestations only for first birth in women aged 35 and older (study group n = 143) we...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000064689
更新日期:2002-01-01 00:00:00
abstract::Acupuncture treatment in the final weeks of pregnancy has been claimed to shorten the duration of labor in primiparous women. In the present study, the length of the various phases of labor was calculated for 56 primiparous women who were repeatedly treated with manual acupuncture during the month prior to parturition...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298806
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:Human placentae from normal and pre-eclamptic pregnancies were evaluated for possible changes in gene expression by microarray analysis to uncover new clues for the research of the etiology of pre-eclampsia. METHODS:Placentae from five normal pregnancies and five pregnancies complicated by pre-eclampsia were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092857
更新日期:2006-01-01 00:00:00
abstract::Cesarean sections were performed in 24 cases before the end of the 32nd week of pregnancy. Despite the fact that the indications for the operations were severe obstetric complications, the perinatal mortality was 25%, which should be compared to 23% for all children born in Sweden at that age., 2 of the surviving chil...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299827
更新日期:1980-01-01 00:00:00
abstract::We herein present a case of exencephaly with rachischisis, situs ambiguous and club feet, diagnosed antenatally by ultrasound. This combination of anomalies is very rare. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293305
更新日期:1990-01-01 00:00:00
abstract::The concentration of collagen in the human uterine cervix decreases during pregnancy. This change contributes to the ripening process, which facilitates cervical dilatation during labor. It has been suggested that cervical collagen is partly degraded at term and after delivery. In order to evaluate this hypothesis we ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298975
更新日期:1985-01-01 00:00:00
abstract::Human seminal plasma from normal or patients with abnormal parameters of the ejaculates contains an inhibitory material that expresses potent in vitro inhibitory activity on PHA-M-induced blast transformation and NK activity. Using the test of inhibition of NK activity, the semen samples from individuals with higher c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298834
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of this meta-analysis was to determine whether frozen embryo transfer (ET) increases ectopic pregnancy (EP) rate compared with fresh ET. METHODS:A meta-analysis was performed of data from seven comparative studies including 13,059 pregnancies that resulted from nondonor in vitro fertilization c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,meta分析
doi:10.1159/000213048
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:All current major medications in treating endometriosis are effective in treating pain, most likely through suppression of proliferation of the implants, yet their effectiveness is relatively short term and they all have many undesirable, and sometimes severe, side effects. There is pressing need for novel, ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000093975
更新日期:2006-01-01 00:00:00
abstract::The present study investigated plasma activity of 5'-nucleotidase, a key enzyme in the production of adenosine, in pre-eclampsia, and evaluated the relationship between changes in 5'-nucleotidase activity, and levels of uric acid, endproduct of the purine metabolism, and the severity of pre-eclampsia. We measured plas...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000067886
更新日期:2002-01-01 00:00:00
abstract::An extremely rare case of partial hydatidiform mole located in the right Fallopian tube was diagnosed by ultrasonography and computed tomography. The lesion was excised, and the human chorionic gonadotropin (HCG) level in early morning urine fell below 1,000 IU/ml on postoperative day 11, and the serum HCG-beta level ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292708
更新日期:1993-01-01 00:00:00
abstract::The relative roles of the cyclic nucleotide messengers cAMP and cGMP in the suppression of follicle-stimulating hormone (FSH) secretion in response to inhibin (IBN) were assessed employing rat gonadotropes in monolayer culture. While exposure of cells to gonadotropin-releasing hormone (GnRH) induced a significant incr...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298808
更新日期:1987-01-01 00:00:00
abstract::Hysteroscopic surgery is widely used for the treatment of patients suffering from menorrhagia. In different studies, pretreatment of the endometrium with GnRH analogues (GnRH-a) prior to endometrial ablation has been reported to increase the success rate, as well as to reduce the menstrual blood flow, accounting for a...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000052847
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:This study is aimed at comparing the early diagnostic accuracy of maternal blood white blood cell (WBC) count, C-reactive protein (CRP) and procalcitonin in predicting early onset neonatal sepsis (EONS) among early preterm premature rupture of membrane (PPROM) pregnancies. METHODS:A total of 57 consecutive ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000446949
更新日期:2017-01-01 00:00:00
abstract::Anterior colporrhaphy (Kelly-Stoeckel suture) was performed on 22 women suffering from grade-I or grade-II genuine stress incontinence. Urodynamic investigation was performed on every patient before surgery and 6 months postoperatively. 21 patients were cured and 1 patient improved. After operation the functional uret...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010196
更新日期:1999-01-01 00:00:00
abstract::A total of 171 consecutive high-risk parturients in Maputo Central Hospital were studied regarding post-partum contraceptive choice in order to plan a new post-natal clinic approach in maternal health care. It was found that contraceptive interest was much less in women with experience of child loss than in women with...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294887
更新日期:1992-01-01 00:00:00
abstract::Pathologic material was reviewed and survival data were obtained on 182 of the endometrial cancer patients reported in our previous study (1975) to compare histopathologic characteristics and clinical behavior (survival) between endometrial adenocarcinoma in estrogen users and nonusers. In addition, relative risk esti...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299600
更新日期:1981-01-01 00:00:00
abstract:AIM:The aim of this study was to evaluate whether natural fertility is related to serum 25-hydroxyvitamin D (25-OH-vitamin D) levels. METHODS:A nested case-control study was designed from a prospective cohort of pregnant women undergoing first trimester screening for aneuploidies. Cases included women seeking pregnanc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000443397
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To investigate the clinical and prognostic significance of human papillomavirus (HPV) in a Chinese population of cervical cancers. METHODS:We studied 121 cervical cancer tissue samples from patients treated at our hospital. Identification and typing of HPV were done by polymerase chain reaction (PCR) using c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052925
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on the release of progesterone by trophoblast cells in vitro. METHODS...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000080073
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of depot medroxy progesterone acetate (DMPA) as a preparatory agent for endometrial resection. STUDY DESIGN:Endometrial resection was performed on 50 women for excessive uterine bleeding. The patients were randomly divided into 2 equal groups, with the first group receiving DMPA and ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000052969
更新日期:2001-01-01 00:00:00
abstract::Glycogen, glucose, some nucleosides and purine base derivatives were determined in biopsies from 10 term pregnant women undergoing elective cesarean sections before labor. The concentrations were compared in the biopsies which were cut from isthmus and fundus of the uterus and m. rectus abdominis. M. rectus biopsies h...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010086
更新日期:1999-01-01 00:00:00
abstract::There is no current consensus on the best treatment modality for cesarean scar pregnancy (CSP) with favorable reproductive and pregnancy outcome. We treated 3 cases of symptomatic CSP with fetal cardiac activity. The first case underwent laparoscopic repair at 6 weeks' gestational age of unruptured CSP. The second pat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000364867
更新日期:2014-01-01 00:00:00
abstract::Advances in fetal echocardiography enable the prenatal diagnosis of a vast majority of congenital heart defects. On the other hand, ostium secundum atrial septal defect is difficult to diagnose in the fetus. Although a defect of minor clinical significance, this may be the only intrauterine finding of a chromosomal an...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009910
更新日期:1998-01-01 00:00:00
abstract::The aim of this study was to explore the antimicrobial activity of human follicular fluid (HFF), to test the hypothesis that different strains of the same bacterial species could display different patterns of susceptibility to antimicrobial action of HFF, and to preliminarily investigate the possible mechanism of anti...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000074103
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate the degree of pain during and after office hysteroscopy with combined intracervical and intrauterine anesthesia compared to intracervical anesthesia only. METHODS:We evaluated the amount of pain experienced during office hysteroscopy using combined local intracervical and intrauterine anest...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000252957
更新日期:2010-01-01 00:00:00
abstract::The function of adrenoceptors in the female genital tract was tested estimating the uptake of 3H-noradrenaline (3H-NA) in vitro in oviductal, uterine arterial and myometrial tissue samples obtained from 74 women. The highest 3H-NA value, 64 +/- 5 ng/g, was in the oviduct (p less than 0.001 vs. uterine artery and myome...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293673
更新日期:1988-01-01 00:00:00
abstract::In vitro production of progesterone and estradiol by human corpora lutea of different ages was evaluated in the presence or absence of human chorionic gonadotrophin (HCG). Progesterone production by the luteal tissue was enhanced by as little as 0.1 IU/ml HCG and maximally stimulated by approximately 10 IU/ml HCG. Est...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293698
更新日期:1988-01-01 00:00:00