Abstract:
BACKGROUND/AIMS:To evaluate the degree of pain during and after office hysteroscopy with combined intracervical and intrauterine anesthesia compared to intracervical anesthesia only. METHODS:We evaluated the amount of pain experienced during office hysteroscopy using combined local intracervical and intrauterine anesthesia, 10, 30, and 60 min after, and during endometrial biopsy prospectively in 37 infertile women (study group). We used a visual analog scale ranging from 0 to 10. Seventy-six women who received only intracervical anesthesia served as historical controls. RESULTS:The mean ages of patients in the control and study groups were comparable. Patients' perception of pain was significantly higher during endometrial biopsy than during or after hysteroscopy in the study patients (p < 0.01, 95% CI 0-3). The mean pain score in the control group was significantly higher than that in the study group during hysteroscopy (3.3 +/- 0.2 vs. 2.2 +/- 0.3; p < 0.05, 95% CI 0-2). However, there was no significant difference in the pain scores between the control and study groups during endometrial biopsy and 10, 30, and 60 min after the procedure. CONCLUSION:Endometrial biopsy is associated with more pain than office hysteroscopy. Additional intrauterine anesthesia with 1% lidocaine significantly reduces pain sensation during office hysteroscopy.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Agdi M,Tulandi Tdoi
10.1159/000252957subject
Has Abstractpub_date
2010-01-01 00:00:00pages
30-2issue
1eissn
0378-7346issn
1423-002Xpii
000252957journal_volume
69pub_type
杂志文章abstract::Mesh of absorbable polyglactin 910 instead of human tissues or nonabsorbable synthetic materials was utilized for retropubic sling procedures in 21 women with urinary stress incontinence. The patients have been observed for a period ranging from 4 to 14 months. 20 of them are continent while there was 1 relapse after ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299212
更新日期:1983-01-01 00:00:00
abstract:AIMS:To construct in vitro models of normal uterine arterial vascular network through vascular corrosion casting and explore their characteristics and clinical significances. METHODS:Three sets of uterus, vagina and bilateral adnexa were perfused and cast via uterine artery and ovarian artery, using 25, 20 and 15% chl...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000245941
更新日期:2010-01-01 00:00:00
abstract:AIMS:To compare a surgical-margin thermal artifact in 3 techniques of loop excision of the transformation zone (LETZ). METHODS:The histopathologic specimens from 140 patients who underwent 3 techniques of LETZ with different electrosurgical units (large loop used with a Valleylab, large loop used with an Ellman Surgit...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000333438
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Previous publications examined the endocrinology of follicular stimulation, focusing on luteinizing hormone (LH) levels changes. In selected, good prognosis IVF patients, a sharp drop in LH serum level was demonstrated between cycle days 2 and 6. OBJECTIVE:The purpose of this study was to examine if this ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000505688
更新日期:2020-01-01 00:00:00
abstract:AIM:We investigated whether there is a correlation between morphological changes of the lower uterine segment after caesarean section (CS), visualized by means of either a transvaginal sonography (TVS) or a sonohysterography (SHG), and the frequency of abnormal uterine bleedings reported by the women. METHODS:By means...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000091497
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:Premature labor is still the leading cause of infant mortality and morbidity worldwide. Multiple etiological factors including genetics and environment are held responsible for preterm birth. However, scientific data regarding the link between premature birth and genetics are limited. SUBJECTS AND METHODS:In...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000237743
更新日期:2009-01-01 00:00:00
abstract::The rate of spontaneous and methotrexate (MTX)-induced chromosome breakage was studied in individuals with a history of habitual abortions in whom a structural chromosomal aberration was found in a single cell during routine cytogenetic analysis. Twelve such individuals were selected because they were not under the in...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292599
更新日期:1993-01-01 00:00:00
abstract::Ciliary neurotrophic factor (CNTF) is a gp130 neuroregulatory cytokine belonging to the interleukin-6-type cytokine superfamily. Several lines of evidence suggest that the concentrations of interleukin-6 are elevated in the peritoneal fluid of endometriosis patients. To our knowledge, no study on whether this might al...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000072694
更新日期:2003-01-01 00:00:00
abstract:AIM:The aim of this study was to assess various treatment options in stage IB2 cervical cancer patients. METHODS:Between January 1995 and May 2007, 63 patients with stage IB2 were treated by radical hysterectomy (n = 28), primary concurrent chemoradiation (CCRT, n = 16) or radiation therapy (RT, n = 19). Disease-free ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000320722
更新日期:2011-01-01 00:00:00
abstract::A prospective randomized trial comprising 90 patients was undertaken to evaluate three different regimens of tinidazole in the treatment of anaerobic vaginosis. Each group consisted of 30 women. The three regimens were: (A) oral tinidazole (150 mg X 2) for 7 days, (B) same oral treatment as above but also the partner ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000293524
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND/AIMS:Some embryo implantation problems in patients with recurrent implantation failure may be explained by the inability of the embryo to hatch out of its zona pellucida. In this case-control study, a study group which had received modified quarter laser-assisted zona thinning (mQLAZT) was compared with a co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000171068
更新日期:2009-01-01 00:00:00
abstract:AIMS:To document progress with human papillomavirus (HPV) vaccine introduction in three closely related European countries, one with organized (the Netherlands) and two with opportunistic cervical cancer screening (Belgium and Luxembourg). METHODS:Experts involved in cervical cancer screening and national immunization...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000314010
更新日期:2010-01-01 00:00:00
abstract::Endometriosis is a sex steroids-dependent disease. It has been postulated that certain genetic polymorphisms involved in sex steroids biosynthesis and metabolisms may be associated with increased risk of developing endometriosis. Despite a deluge of reports of positive associations of endometriosis with numerous polym...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000089011
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/AIMS:To determine the clinicopathological characteristics and potentially associated outcomes in patients diagnosed with serous adenocarcinoma of the uterine cervix. METHODS:The records of surgically-treated patients with pathological stage pT1b-2b serous adenocarcinoma were reviewed. RESULTS:Of 12 patient...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000329319
更新日期:2012-01-01 00:00:00
abstract::Thyroxine-binding globulin (TBG) and free thyroxine (FT4) were studied in 172 apparently healthy women giving birth to malformed children. The malformations were divided into two groups: minor malformations (group A) and major malformations (group B). The blood samples were usually drawn in the first trimester. Group ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293608
更新日期:1989-01-01 00:00:00
abstract::Oviducts of 35 mature, white New Zealand rabbits were injured by a laser beam, using various powers from 25 to 40 W, and by a series of pulses of 1/10, 1/20 or 1/100 s duration. The contralateral oviducts served as controls and were injured at similar areas by a scalpel. The injured areas of both tubes were histologic...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299610
更新日期:1981-01-01 00:00:00
abstract::The morphological effect of a high-dose progestogen (Depo-Provera) on highly differentiated endometrial carcinoma was studied. Thirteen patients were treated by progestogen only, given at the beginning of the treatment in a weekly dose of 1,000 mg for 3 month. Then, progestogen 500 mg was administered for 12 months. N...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298812
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To compare the qualitative (QL) and quantitative (QN) levels of betahCG in cervicovaginal secretions as predictors of preterm birth. METHODS:The study included 100 women. QL and QN assays were done with velocit kit and ELISA, respectively. RESULTS:A positive QL assay had sensitivity of 78%, specificity 95%,...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000189917
更新日期:2009-01-01 00:00:00
abstract::Advances in fetal echocardiography enable the prenatal diagnosis of a vast majority of congenital heart defects. On the other hand, ostium secundum atrial septal defect is difficult to diagnose in the fetus. Although a defect of minor clinical significance, this may be the only intrauterine finding of a chromosomal an...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009910
更新日期:1998-01-01 00:00:00
abstract:AIMS:Vulvar cancer is a rare disease. In western European countries, the incidence is 1.2 cases per 100,000 women/year. The aim of this study was to analyze the management and disease-free survival (DFS) of vulvar cancer among European countries. METHODS:An international multicenter retrospective study including patie...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,多中心研究
doi:10.1159/000452097
更新日期:2017-01-01 00:00:00
abstract::The pathophysiology of postpartum urinary retention (PUR) is still unclear. The prevalence rate varies with the definition used and the literature discusses various risk factors. Bladder catheterization is the treatment of choice, but the best way to do it is not ascertained. Long-term sequelae seem to be rare. There ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000099306
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To clarify the alteration of maternal-fetal mixed lymphocyte reaction (MLR) in intrahepatic cholestasis of pregnancy (ICP). METHODS:Twenty-two patients with intrahepatic cholestasis of pregnancy and 21 normal pregnant women were recruited into the present study. Of patients with ICP, 5 also experienced pregn...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000068381
更新日期:2002-01-01 00:00:00
abstract::To determine the relationship between abnormal fetal heart rate (FHR) patterns, fetal oxygen content by reflectance pulse oximetry, and the effects of maternal oxygen administration, 158 intrapartum women consisting of 120 women with normal FHR patterns, and 38 women with varying degrees of variable FHR decelerations ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291404
更新日期:1997-01-01 00:00:00
abstract::Maternofetal transfer of ritodrine and its effect on placental glucose and oxygen consumption were studied using a recycling perfusion of maternal and fetal circulations of an isolated cotyledon of a term human placenta. 3H-labeled ritodrine was introduced into the maternal side of the perfusion system. Transfer was c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292983
更新日期:1991-01-01 00:00:00
abstract:AIM:To evaluate the clinical application of the new Hologic quantitative foetal fibronectin (qfFN) bedside test for the prediction of spontaneous preterm birth (sPTB) in patients with symptoms suggestive of spontaneous threatened preterm labour (sPTL). METHODS:A prospective observational study with 154 pregnant women ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000480235
更新日期:2018-01-01 00:00:00
abstract::Of 903 surgically treated patients with endometriosis the disease recurred in 132 cases (14.6%) during the follow-up period of 6-10 years. The re-operation was performed within 1 year after the primary operation for 7 patients, within 1-5 years for 91 patients and more than 5 years after the primary surgery for 34 pat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299851
更新日期:1980-01-01 00:00:00
abstract::The success rate after intraperitoneal insemination is also imputed to superovulation protocols. We report here the first case, to our knowledge, of pregnancy following intraperitoneal insemination during a natural cycle. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293342
更新日期:1990-01-01 00:00:00
abstract::The obstetrician is rarely confronted with a pregnant patient who presents with a large suspicious pelvic mass. Diagnostic tools are not always of value and laparotomy may be performed for obstetric and histopathologic reasons. In this article we present an interesting case of an unusual pelvic mass in pregnancy secon...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293507
更新日期:1989-01-01 00:00:00
abstract::Anterior colporrhaphy (Kelly-Stoeckel suture) was performed on 22 women suffering from grade-I or grade-II genuine stress incontinence. Urodynamic investigation was performed on every patient before surgery and 6 months postoperatively. 21 patients were cured and 1 patient improved. After operation the functional uret...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010196
更新日期:1999-01-01 00:00:00
abstract::A rare type of cervical squamous cell carcinoma with pseudoglandular features occurred in a 22-year-old woman. Histological and ultrastructural characteristics of this tumor with keratinized cells as well as glandular mucin containing structures and intracellular luminal formations are presented. The problems associat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299386
更新日期:1983-01-01 00:00:00