Continuous, high-dose progestogen treatment of endometrial cancer.

Abstract:

:The morphological effect of a high-dose progestogen (Depo-Provera) on highly differentiated endometrial carcinoma was studied. Thirteen patients were treated by progestogen only, given at the beginning of the treatment in a weekly dose of 1,000 mg for 3 month. Then, progestogen 500 mg was administered for 12 months. Nine patients were operated after the treatment; in 7 of them, a total histological regression was observed. Histological tests of the intraoperatively gained preparations showed 'disappearance' of the original carcinomatous process; only a serious atrophy of the endometrium could be detected.

journal_name

Gynecol Obstet Invest

authors

Szarvas Z,Zsolnai B,Gimes G,Hidvégi J

doi

10.1159/000298812

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

262-6

issue

4

eissn

0378-7346

issn

1423-002X

journal_volume

24

pub_type

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