Sex steroid hormones influence the cAMP content in human endometrium during the menstrual cycle.

Abstract:

:The measurement of the tissue concentrations of cyclic adenosine monophosphate (cAMP) in human endometrium shows that the levels of the nucleotide vary during the menstrual cycle, being 11.4 +/- (SE) 2.5 and 37.7 +/- (SE) 10.1 pmol/mg protein in the proliferative and secretory phase, respectively. The individual determinations of cAMP are significantly correlated to the estradiol/progesterone blood concentration ratio: by this means we obtained a superimposable distribution with the results of histologic examination suggesting that the hormones have a direct action in determining the cAMP levels in this tissue. The relevance of these observations for the physiology of the endometrium is discussed.

journal_name

Gynecol Obstet Invest

authors

Pansini F,Bergamini CM,Bettocchi S Jr,Malfaccini M,Santoiemma M,Scoppetta V,Bagni B,Mollica G

doi

10.1159/000299076

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

174-7

issue

4

eissn

0378-7346

issn

1423-002X

journal_volume

18

pub_type

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