Abstract:
:The measurement of the tissue concentrations of cyclic adenosine monophosphate (cAMP) in human endometrium shows that the levels of the nucleotide vary during the menstrual cycle, being 11.4 +/- (SE) 2.5 and 37.7 +/- (SE) 10.1 pmol/mg protein in the proliferative and secretory phase, respectively. The individual determinations of cAMP are significantly correlated to the estradiol/progesterone blood concentration ratio: by this means we obtained a superimposable distribution with the results of histologic examination suggesting that the hormones have a direct action in determining the cAMP levels in this tissue. The relevance of these observations for the physiology of the endometrium is discussed.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Pansini F,Bergamini CM,Bettocchi S Jr,Malfaccini M,Santoiemma M,Scoppetta V,Bagni B,Mollica Gdoi
10.1159/000299076subject
Has Abstractpub_date
1984-01-01 00:00:00pages
174-7issue
4eissn
0378-7346issn
1423-002Xjournal_volume
18pub_type
杂志文章abstract::The crisis frequency of stress incontinence (SI) is known to be high among pregnant women. This preliminary study was performed to determine whether the diagnostic standard of the Q-tip test used in the diagnosis of SI in nonpregnant women is applicable to pregnant women. The Q-tip tests were performed regularly durin...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000052900
更新日期:2001-01-01 00:00:00
abstract::Pre-implantation blastocysts or trophoblast, obtained from ectoplacental cones, were transferred to the right oviducts of both pregnant and nonpregnant mice. Blastocysts which remained within the oviductal lumen did not show evidence of further differentiation into trophoblast although they readily implanted on variou...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299117
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND/AIMS:To determine the clinicopathological characteristics and potentially associated outcomes in patients diagnosed with serous adenocarcinoma of the uterine cervix. METHODS:The records of surgically-treated patients with pathological stage pT1b-2b serous adenocarcinoma were reviewed. RESULTS:Of 12 patient...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000329319
更新日期:2012-01-01 00:00:00
abstract::Maternal heart rate variability was evaluated by means of 24-hour Holter ECG monitoring in three groups of patients (15 preeclamptic, 15 women hospitalized due to other complications and 15 normal ambulatory pregnant women) in the 28th-33rd week of gestation. Heart rate variability was estimated by time and frequency ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009949
更新日期:1998-01-01 00:00:00
abstract::Guillain-Barré syndrome (GBS) is an acute or subacute demyelinating polyneuropathy that rarely complicates pregnancy, but increases maternal and perinatal morbidity. A 15-year-old pregnant woman was admitted with ascending paralysis and acellular lumbar puncture suggestive of GBS. She required mechanical ventilation f...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000209215
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Angioleiomyoma (ALM) is a rare, benign neoplasm involving the peripheral soft tissues. ALM has not previously been described to originate from the ovary. We present a case herein of a premenarchal girl with a large ALM originating from the ovary. CASE:An 11-year-old girl underwent a laparotomy during the co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000113083
更新日期:2008-01-01 00:00:00
abstract::Breast involvement in ovarian cancer is extremely rare. We report a case of solitary breast metastasis from ovarian carcinoma in a 43-year-old white woman, 3 months following diagnosis of ovarian cancer. The diagnostic, therapeutic and prognostic aspects as well as a review of the literature of this uncommon site of m...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052946
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/AIMS:A phase II study was conducted to assess the activity and toxicity of weekly docetaxel in patients with advanced or recurrent cancer of the cervix. METHODS:Eligible patients were required to have measurable disease with adequate performance status, bone marrow, renal and hepatic function. Patients were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000106489
更新日期:2007-01-01 00:00:00
abstract::Fetal atrial septal aneurysm (ASA) is uncommon and little is known regarding its prevalence and clinical significance. In this report we describe 2 cases of fetal ASA diagnosed by ultrasonography. They were referred for examination because of fetal tachyarrhythmia in 1 case, and polyhydramnios in the other. The first ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000292030
更新日期:1996-01-01 00:00:00
abstract::The relationship between age and urodynamic parameters was studied cross-sectionally in a group of 28 women in whom clinically and urodynamically both stress incontinence and detrusor instability were excluded (no proven incontinence, NPI) and in a group, matched for age, with genuine stress incontinence (GSI). At all...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294858
更新日期:1992-01-01 00:00:00
abstract::The objective of the study was to evaluate the effects of antenatal corticosteroid therapy in multiple pregnancy on the incidence and severity of respiratory distress syndrome (RDS). Twenty-two women with twin, 12 with triplet and 2 with quadruplet pregnancies and an emergency group of 20 mothers with twin pregnancies...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052936
更新日期:2001-01-01 00:00:00
abstract:AIMS:This study compared the effectiveness of solifenacin succinate (SS) versus percutaneous tibial nerve stimulation (PTNS) in women with overactive bladder syndrome (OABS). METHODS:A randomized controlled crossover study of 40 women with OABS was performed. Patients were randomized into two groups. In group A, patie...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,随机对照试验
doi:10.1159/000350216
更新日期:2013-01-01 00:00:00
abstract::Sixty postmenopausal women were randomly assigned to three types of treatment with intranasal salmon calcitonin (SCT) plus calcium 500 mg daily (group A: 100 IU daily of SCT; group B: 100 IU daily of SCT for alternate cycles of 2 months with a 1-month interval; group C: 100 IU daily of SCT for alternate cycles of 3 mo...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000294874
更新日期:1992-01-01 00:00:00
abstract::A case of high levels of specific IgM antibodies registered by the immunosorbent agglutination assay (ISAgA) in a pregnant woman with a history of toxoplasmosis is reported. The patient had acute lymphoglandular toxoplasmosis diagnosed serologically by increases in the specific antibody titer detected by the Sabin-Fel...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293151
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:Limited information is available regarding the quantity of blood loss associated with uncomplicated transvaginal oocyte retrieval. The aim of the present study was evaluating the quantity of such a loss. METHODS:One hundred and fifty consecutive women undergoing oocyte retrieval were recruited. They un...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000158649
更新日期:2009-01-01 00:00:00
abstract::Choriocarcinoma coexistent with an intrauterine pregnancy is rare and requires decisions affecting mother and child to treat this aggressive tumor. An instance of this situation is presented to highlight clinical circumstances that warrant departure from accepted dogma. Pathologic aspects of choriocarcinoma are also d...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000363234
更新日期:2015-01-01 00:00:00
abstract:AIMS:To determine the cut-off level of endometrial thickness for detecting endometrial disease on a large scale of screening and to examine the usefulness of transvaginal ultrasonography (TVS) for endometrial disease screening in asymptomatic postmenopausal Japanese women. METHODS:The study involved 1,400 postmenopaus...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000087375
更新日期:2005-01-01 00:00:00
abstract::We analyzed 81 ovarian cancers for loss of heterozygosity (LOH) on 10q23 and for mutations in PTEN. LOH was common among the endometrioid (43%) and serous (28%) cancers, but was infrequent among the other histological subtypes. Somatic PTEN mutations were detected in seven (21%) endometrioid cancers and the mutation i...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000052877
更新日期:2000-01-01 00:00:00
abstract:AIMS:To compare a surgical-margin thermal artifact in 3 techniques of loop excision of the transformation zone (LETZ). METHODS:The histopathologic specimens from 140 patients who underwent 3 techniques of LETZ with different electrosurgical units (large loop used with a Valleylab, large loop used with an Ellman Surgit...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000333438
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To evaluate whether prolactin, alpha-fetoprotein (AFP) or B-human chorionic gonadotropin (BHCG) is the most effective marker in vaginal fluid for diagnosing prelabor rupture of membranes (PROM). These proteins are present in amniotic and vaginal fluid and have been reported to be potent markers of PROM, but h...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000097844
更新日期:2007-01-01 00:00:00
abstract::Changes in norepinephrine following a bimanual handgrip contraction test were used to evaluate the contribution of static physical effort exerted by the parturient on the rise in adrenergic stimulation observed during ongoing labor. Noradrenaline baseline values were 306.71 +/- (SE) 21.5 pg/ml); and after a maximal ef...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298871
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Group B streptococcus (GBS) is an important cause of neonatal sepsis. Guidelines advise to collect cultures at 35-37 weeks' gestation and to administer intrapartum antibiotic prophylaxis in case of GBS-positive cultures, as well as in all preterm deliveries. Improved effectiveness of antenatal cultures might...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000265942
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To determine whether, in addition to treatment with antibiotics, it is necessary to remove the intrauterine device (IUD) to eliminate genital colonization by Actinomyces. METHODS:A randomized clinical trial was carried out. Patients were divided into two groups. The intervention group did not have their IUDs...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000052955
更新日期:2001-01-01 00:00:00
abstract::17 beta-Estradiol (E2), basal body temperature (BBT) and luteinizing hormone (LH), were measured in normally menstruating women. The preovulatory E2 observations were characterized by variations about a constant level during the preovula-peak. The BBT observations typically varied about a constant level during the pre...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299523
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:Human placentae from normal and pre-eclamptic pregnancies were evaluated for possible changes in gene expression by microarray analysis to uncover new clues for the research of the etiology of pre-eclampsia. METHODS:Placentae from five normal pregnancies and five pregnancies complicated by pre-eclampsia were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092857
更新日期:2006-01-01 00:00:00
abstract::Oviducts of 35 mature, white New Zealand rabbits were injured by a laser beam, using various powers from 25 to 40 W, and by a series of pulses of 1/10, 1/20 or 1/100 s duration. The contralateral oviducts served as controls and were injured at similar areas by a scalpel. The injured areas of both tubes were histologic...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299610
更新日期:1981-01-01 00:00:00
abstract::The relationship between contraction changes and cAMP production under long-term application of ritodrine was investigated using longitudinal muscle strips of pregnant (Day 21) rat uterus. Cellular cAMP gradually increased up to 20 min, then decreased to the control level and fluctuated after 90 min in the presence of...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293119
更新日期:1991-01-01 00:00:00
abstract::Tubal occlusion using Filshie clip is one of the most commonly performed operations for female sterilization. It is usually a simple and safe procedure, and operative complications are uncommon. We report a rare case of spontaneous expulsion of a Filshie clip through the anterior abdominal wall 5 years after steriliza...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000070615
更新日期:2003-01-01 00:00:00
abstract::Immunochemical methods were used to identify neuropeptide Y (NPY) in the cervical tissue of women at early and term pregnancy. NPY-containing fibers could not be demonstrated in the upper and lower uterine segments at term, but the cervical innervation persisted during labor. Moreover, NPY alone did not affect cervica...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292754
更新日期:1992-01-01 00:00:00
abstract::To elucidate the mechanism of the type 2 carbohydrate chain accompanying the development of endometrial cancer, we studied the expression of beta-1,4-galactosyltransferase (beta-1,4GT) in normal endometrial and endometrial cancer tissues. An immunohistochemical study revealed that beta-1,4GT was diffusely positive in ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010158
更新日期:1999-01-01 00:00:00