Ploidy analysis and S-phase fraction determination by flow cytometry in anembryonic pregnancy and spontaneous abortions.

Abstract:

:The nuclear DNA content of 20 anembryonic pregnancies was studied by flow cytometry from paraffin embedded tissue blocks. An abnormal amount of DNA content was found in 8 of the cases. This was a significantly higher percentage than encountered in spontaneous abortions studied by the same population (40 and 9%, respectively, p < 0.05). The S-phase fraction in anembryonic pregnancies was lower than in spontaneous abortions (22.4 +/- 12.7 and 35.4 +/- 6.8, respectively, p < 0.01). The results indicated that abnormal embryogenesis with grave chromosomal aberrations may play a major role in the etiology of anembryonic pregnancy.

journal_name

Gynecol Obstet Invest

authors

Ozeren M,Aydemir V,Tekelioglu Y,Topçuoglu K,Bozkaya H

doi

10.1159/000010149

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

104-7

issue

2

eissn

0378-7346

issn

1423-002X

pii

10149

journal_volume

48

pub_type

临床试验,杂志文章
  • Cyclic changes in cervical microflora and their effect on infections following hysterectomy.

    abstract::In a prospective study the cyclic changes in the cervical microflora and the endometrial histology were correlated with the incidence of postoperative infections in 99 women undergoing elective abdominal hysterectomy. Escherichia coli and Bacteroides fragilis were isolated more frequently during the proliferative phas...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299447

    authors: Thadepalli H,Savage EW Jr,Salem FA,Roy I,Davidson EC Jr

    更新日期:1982-01-01 00:00:00

  • Sex steroid hormones influence the cAMP content in human endometrium during the menstrual cycle.

    abstract::The measurement of the tissue concentrations of cyclic adenosine monophosphate (cAMP) in human endometrium shows that the levels of the nucleotide vary during the menstrual cycle, being 11.4 +/- (SE) 2.5 and 37.7 +/- (SE) 10.1 pmol/mg protein in the proliferative and secretory phase, respectively. The individual deter...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299076

    authors: Pansini F,Bergamini CM,Bettocchi S Jr,Malfaccini M,Santoiemma M,Scoppetta V,Bagni B,Mollica G

    更新日期:1984-01-01 00:00:00

  • Antenatal sonographic diagnosis of exencephaly.

    abstract::We herein present a case of exencephaly with rachischisis, situs ambiguous and club feet, diagnosed antenatally by ultrasound. This combination of anomalies is very rare. ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293305

    authors: Abu Musa A,Hata T,Senoh D,Makihara K,Aoki S,Hata K,Takamiya O,Mochida T,Kitao M,Tanaka O

    更新日期:1990-01-01 00:00:00

  • Clinical Application of Quantitative Foetal Fibronectin for the Prediction of Preterm Birth in Symptomatic Women.

    abstract:AIM:To evaluate the clinical application of the new Hologic quantitative foetal fibronectin (qfFN) bedside test for the prediction of spontaneous preterm birth (sPTB) in patients with symptoms suggestive of spontaneous threatened preterm labour (sPTL). METHODS:A prospective observational study with 154 pregnant women ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000480235

    authors: Radford SK,Da Silva Costa F,Araujo Júnior E,Sheehan PM

    更新日期:2018-01-01 00:00:00

  • Evaluation of fetal sonographic measurements in the first trimester by transvaginal sonography.

    abstract::To assess the reliability of early biometric measurements in pregnancy, transvaginal sonography was performed in 92 pregnancies in the first trimester in a cross-sectional fashion. Measurements included crown-to-rump length (CRL), biparietal diameter (BPD), head and abdominal circumference (HC and AC), and femur lengt...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293032

    authors: Izquierdo LA,Kushnir O,Smith JF,Gilson GJ,Chatterjee MS,Qualls C,Curet LB

    更新日期:1991-01-01 00:00:00

  • Prospective Randomized Trial Comparing Embryo Transfers of Cases with and without Catheter Rotation during Its Withdrawal.

    abstract:OBJECTIVE:To compare embryo transfer (ET) technique based on catheter rotation during its withdrawal in cases with unexplained infertility in a prospective, randomized trial (NCT03097042). METHODS:Two hundred intracytoplasmic sperm injection (ICSI) patients undergoing ET with cleaving or blastocyst-stage fresh embryos...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000489493

    authors: Yayla Abide C,Ozkaya E,Sanverdi I,Bostancı Ergen E,Kurek Eken M,Devranoglu B,Bilgiç BE,Kilicci C,Kayatas Eser S

    更新日期:2018-01-01 00:00:00

  • Unexpected nature of a pelvic mass in pregnancy: Castleman's disease.

    abstract::The obstetrician is rarely confronted with a pregnant patient who presents with a large suspicious pelvic mass. Diagnostic tools are not always of value and laparotomy may be performed for obstetric and histopathologic reasons. In this article we present an interesting case of an unusual pelvic mass in pregnancy secon...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293507

    authors: Başer I,Dilek S,Pabuçcu R,Ulgenalp I,Mermut S,Finci R

    更新日期:1989-01-01 00:00:00

  • Inhibition of lectin-like oxidized low-density lipoprotein receptor 1 protects against plasma/hypoxia-mediated trophoblast dysfunction associated with preeclampsia.

    abstract:BACKGROUND:Preeclampsia (PE) is associated with oxidative stress in the maternal circulation and placenta. This study aimed to determine if inhibition of lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gives protection against oxidative stress-mediated trophoblast dysfunction. METHODS:Plasma and placen...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000370195

    authors: Zhang Y,Ye Y,Wang Y,Chen W

    更新日期:2015-01-01 00:00:00

  • Side effects of tamoxifen in oophorectomized rats.

    abstract:OBJECTIVE:Our objective was to evaluate the direct effect of tamoxifen citrate (TAM) on the endometrium, liver, breast tissue and the lipid profile in oophorectomized (OX) rats. STUDY DESIGN:An experimental animal study. MATERIAL AND METHODS:Forty-one mature rats (33 OX) were randomly divided into four groups and rec...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000009933

    authors: Kafkasli A,Erdem F,Müezzinoglu B,Akbaşak B,Burak F,Aksoy T,Birincioglu M,Biotech MG,Biotec FT

    更新日期:1998-01-01 00:00:00

  • Changes of beta-1,4-galactosyltransferase with the development of endometrial cancer.

    abstract::To elucidate the mechanism of the type 2 carbohydrate chain accompanying the development of endometrial cancer, we studied the expression of beta-1,4-galactosyltransferase (beta-1,4GT) in normal endometrial and endometrial cancer tissues. An immunohistochemical study revealed that beta-1,4GT was diffusely positive in ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010158

    authors: Kubushiro K,Ma J,Fukuchi T,Banno K,Muramatsu Y,Tsukazaki K,Nozawa S

    更新日期:1999-01-01 00:00:00

  • Characterization of P4, a natural inhibitor of cellular cytotoxicity reaction in pregnant women.

    abstract::A factor present in the serum of pregnant women is able to inhibit nonspecifically a cellular cytotoxicity reaction. This glycoprotein called P4, is an alpha-globulin whose molecular weight is 200,000 daltons bound to albumin. Its isoelectric point is 4.1. By its various characteristics, P4 seems different from other ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000298991

    authors: Fizet D,Bousquet J

    更新日期:1985-01-01 00:00:00

  • Pregnancy outcome after the treatment of loop electrosurgical excision procedure or cold-knife conization for cervical intraepithelial neoplasia.

    abstract:OBJECTIVE:The aim of this study was to investigate the influence on fertility and pregnancy outcome in cervical intraepithelial neoplasia (CIN) patients after a loop electrosurgical excision procedure (LEEP) or cold-knife conization (CKC). METHODS:269 patients with CIN-II-III who wanted to conceive were prospectively ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000360538

    authors: Liu Y,Qiu HF,Tang Y,Chen J,Lv J

    更新日期:2014-01-01 00:00:00

  • Long-term effects of valproic acid on reproductive endocrine functions in Turkish women with epilepsy.

    abstract::The long-term effects of valproic acid (VPA) on reproductive endocrine functions in women with epilepsy (WWE) were studied. Serum reproductive hormone concentrations, clinical findings and ovarian morphology were analyzed in 71 WWE who had been receiving antiepileptic drugs (AED) for a minimum of 2 years. Of the 71 WW...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000203537

    authors: Gorkemli H,Genc BO,Dogan EA,Genc E,Ozdemir S

    更新日期:2009-01-01 00:00:00

  • Heparanase expression and angiogenesis in endometrial cancer.

    abstract::Human heparanase has been shown to function in tumor progression, metastatic spread, and tumor angiogenesis. The aim of the present study was to assess heparanase expression in endometrial cancer in correlation with neovascularization and clinicopathological factors. Forty endometrial cancers were obtained from previo...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000072821

    authors: Watanabe M,Aoki Y,Kase H,Tanaka K

    更新日期:2003-01-01 00:00:00

  • Obstetric outcome in women with endometriosis--a matched case-control study.

    abstract:BACKGROUND:Immunological deficiencies, altered angiogenic activity, infiltrative potential and growth factors are plausible factors behind endometriosis. The aim of this study was to determine whether endometriosis interferes with the course or outcome of pregnancy. STUDY DESIGN:In this matched case-control study, we ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000074815

    authors: Kortelahti M,Anttila MA,Hippeläinen MI,Heinonen ST

    更新日期:2003-01-01 00:00:00

  • Intranasal salmon calcitonin in postmenopausal osteoporosis: effect of different therapeutic regimens on vertebral and peripheral bone density.

    abstract::Sixty postmenopausal women were randomly assigned to three types of treatment with intranasal salmon calcitonin (SCT) plus calcium 500 mg daily (group A: 100 IU daily of SCT; group B: 100 IU daily of SCT for alternate cycles of 2 months with a 1-month interval; group C: 100 IU daily of SCT for alternate cycles of 3 mo...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000294874

    authors: Perrone G,Galoppi P,Valente M,Capri O,D'Ubaldo C,Anelli G,Zichella L

    更新日期:1992-01-01 00:00:00

  • Bridge Suture for Successful McDonald Emergency Cerclage.

    abstract:OBJECTIVES:To create awareness about a surgical technique termed bridge suture, which is performed as a pretreatment before a McDonald cerclage is performed on an emergency to treat severe cervical insufficiency. METHODS:Procedures for bridge suture were reviewed in detail and outcomes of 16 patients treated with brid...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000452099

    authors: Tanaka M,Hori Y,Shirafuji A,Kato M,Kato J,Kobayashi H,Tsuchida T,Fukae T

    更新日期:2017-01-01 00:00:00

  • Anaerobic vaginosis: treatment with tinidazole vaginal tablets.

    abstract::A prospective randomized trial comprising 90 patients was undertaken to evaluate three different regimens of tinidazole in the treatment of anaerobic vaginosis. Each group consisted of 30 women. The three regimens were: (A) oral tinidazole (150 mg X 2) for 7 days, (B) same oral treatment as above but also the partner ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000293524

    authors: Heikkinen J,Vuopala S

    更新日期:1989-01-01 00:00:00

  • Effects of hormone replacement therapy on plasma homocysteine and C-reactive protein levels.

    abstract::In order to investigate the effect of hormone replacement therapy (HRT) on plasma homocysteine and C-reactive protein (CRP) levels 46 healthy postmenopausal women were prospectively enrolled. HRT, which was either 0.625 mg/day conjugated equine estrogen (CEE) plus 2.5 mg/day medroxyprogesterone acetate (MPA) or 0.625 ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000049412

    authors: Yildirir A,Aybar F,Tokgozoglu L,Yarali H,Kabakci G,Bukulmez O,Sinici I,Oto A

    更新日期:2002-01-01 00:00:00

  • Effect of repeated doses of dexamethasone on the incidence and severity of respiratory distress syndrome in multifetal gestation between 24 and 34 weeks.

    abstract::The objective of the study was to evaluate the effects of antenatal corticosteroid therapy in multiple pregnancy on the incidence and severity of respiratory distress syndrome (RDS). Twenty-two women with twin, 12 with triplet and 2 with quadruplet pregnancies and an emergency group of 20 mothers with twin pregnancies...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000052936

    authors: Al-Yatama MK,Al Essa M,Omu AE,Al-Shamali I,Egbase P,Rashwan N

    更新日期:2001-01-01 00:00:00

  • Changes in blood level of lipid peroxide and vitamin E during pregnancy: clinical significance and relation to the pathogenesis of EPH gestosis.

    abstract::The present study was undertaken in order to determine the changes in blood levels of lipid peroxide and vitamin E in EPH gestosis. The mean plasma level of lipid peroxide was 0.89 +/- 0.13 nmol/ml for nonpregnant women, while for normal pregnant women it was 2.51 +/- 0.52 nmol/ml, and 4.10 +/- 0.72 nmol/ml for women ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292473

    authors: Iioka H

    更新日期:1994-01-01 00:00:00

  • Timing of group B streptococcus screening in pregnancy: a systematic review.

    abstract:BACKGROUND:Group B streptococcus (GBS) is an important cause of neonatal sepsis. Guidelines advise to collect cultures at 35-37 weeks' gestation and to administer intrapartum antibiotic prophylaxis in case of GBS-positive cultures, as well as in all preterm deliveries. Improved effectiveness of antenatal cultures might...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,评审

    doi:10.1159/000265942

    authors: Valkenburg-van den Berg AW,Houtman-Roelofsen RL,Oostvogel PM,Dekker FW,Dörr PJ,Sprij AJ

    更新日期:2010-01-01 00:00:00

  • Estrogen and progesterone receptor expression of decidual endometrium in a postmenopausal woman treated with tamoxifen and megestrol acetate.

    abstract::To the best of our knowledge, this is the first report of in vivo endometrial estrogen and progesterone receptor induction as a result of tamoxifen exposure in a postmenopausal breast cancer patient. The following observations, that the postmenopausal endometrium is sensitive to tamoxifen, that this agent can act as a...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292464

    authors: Cohen I,Shulman A,Altaras M,Tepper R,Cordoba M,Beyth Y

    更新日期:1994-01-01 00:00:00

  • Successful management of a solitary peritoneal metastasis of unknown origin. Report of a case.

    abstract::A solitary peritoneal metastasis from a poorly differentiated adenocarcinoma of unknown origin in a 38-year-old female is described. The patient presented with a left ovarian tumor and elevated cancer antigen 125. She underwent complete excision of tumor and received six courses of postoperatively adjuvant cisplatin-b...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291858

    authors: Wang PH,Yuan CC,Chao HT,Lai CR

    更新日期:1997-01-01 00:00:00

  • Positron emission tomography with FDG in the detection of peritoneal and retroperitoneal metastases of ovarian cancer.

    abstract:OBJECTIVE:The aim of this prospective study was to evaluate (18)F-FDG-PET, in comparison with CT, for the detection of peritoneal and retroperitoneal metastases of ovarian cancer. METHODOLOGY:13 patients with primary (n = 7) or recurrent (n = 6) ovarian cancer underwent an attenuation-corrected (18)F-FDG-PET of the ab...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000071525

    authors: Drieskens O,Stroobants S,Gysen M,Vandenbosch G,Mortelmans L,Vergote I

    更新日期:2003-01-01 00:00:00

  • Embryo cleavage rates after oocyte insemination with capacitated sperms in the presence or absence of follicular fluid.

    abstract::The objective of the present study was to compare the rate of embryo cleavage after oocyte insemination with capacitated spermatozoa in the presence or absence of follicular fluid. In the first experiment, a total of 67 oocytes were inseminated with spermatozoa which had been submitted to part of the capacitation proc...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292545

    authors: Franco Júnior JG,Mauri AL,Petersen CG,Baruffi RL,Campos MS,Oliveira JB

    更新日期:1994-01-01 00:00:00

  • Antenatal diagnosis of aberrant umbilical vessels.

    abstract:OBJECTIVE:To evaluate the antenatal screening of aberrant umbilical vessels and assess the association of fetal abnormality with these entities. STUDY DESIGN:444 pregnant women were studied with routine obstetric ultrasound and Doppler color flow imaging in late second trimester or early third trimester. Fetal growth ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291863

    authors: Aoki S,Hata T,Ariyuki Y,Makihara K,Hata K,Kitao M

    更新日期:1997-01-01 00:00:00

  • Postoperative depot medroxyprogesterone acetate versus continuous oral contraceptive pills in the treatment of endometriosis-associated pain: a randomized comparative trial.

    abstract:BACKGROUND/AIM:To evaluate the efficacy and tolerability of postoperative depot medroxyprogesterone acetate (DMPA) versus postoperative continuous oral contraceptive (OC) pills in the treatment of endometriosis-associated pain. METHODS:After a conservative surgery, 84 patients with symptomatic endometriosis were rando...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000337713

    authors: Cheewadhanaraks S,Choksuchat C,Dhanaworavibul K,Liabsuetrakul T

    更新日期:2012-01-01 00:00:00

  • Placental Growth during Normal Pregnancy - A Magnetic Resonance Imaging Study.

    abstract:OBJECTIVE:To investigate normal human placental growth longitudinally throughout the second and third trimesters using MRI. METHODS:Twenty normal, first-time singleton pregnancies were scanned 7 times between the 14th and 38th week of gestation, at 4-week intervals, using MRI. Placental volumes were measured in both s...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000452661

    authors: Langhoff L,Grønbeck L,von Huth S,Axelsson A,Jørgensen C,Thomsen C,Vejlstrup N

    更新日期:2017-01-01 00:00:00

  • Prenatal diagnosis and obstetric management of Larsen's syndrome in a patient with an unrecognized family history of the disease.

    abstract::We report the third case of a prenatal diagnosis of Larsen's syndrome, which is the first report affecting both a 37-year-old primiparous caucasian woman and her fetus not considered to have Larsen's syndrome until the finding of bilateral clubfeet was demonstrated on screening ultrasound at 23 weeks of gestation. His...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010050

    authors: Dören M,Rehder H,Holzgreve W

    更新日期:1998-01-01 00:00:00