Abstract:
:Thyroxine-binding globulin (TBG) and free thyroxine (FT4) were studied in 172 apparently healthy women giving birth to malformed children. The malformations were divided into two groups: minor malformations (group A) and major malformations (group B). The blood samples were usually drawn in the first trimester. Group A showed no significant difference in TBG values compared to women with healthy children. Group B showed lower, but not significantly lower values in earlier pregnancy. However, from the 15th-16th week of pregnancy the TBG values were significantly lower. The FT4 values were in the hyperthyroid range in as much as 20% of the women, compared to the reported rate of 0.2% hyperthyroidism in pregnant women.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Skjöldebrand Sparre LSdoi
10.1159/000293608subject
Has Abstractpub_date
1989-01-01 00:00:00pages
19-21issue
1eissn
0378-7346issn
1423-002Xjournal_volume
27pub_type
杂志文章abstract:OBJECTIVES:The aim of this study is to evaluate oxidative protein damage (OPD) by investigating protein carbonyl (PCO) and nitrotyrosine (NT) levels, oxidative stress by total thiol (T-SH), erythrocyte glutathione (GSH) and nitric oxide (NO) levels in women receiving hormone replacement therapy (HRT). MATERIALS AND ME...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000067718
更新日期:2002-01-01 00:00:00
abstract::Hysteroscopic surgery is widely used for the treatment of patients suffering from menorrhagia. In different studies, pretreatment of the endometrium with GnRH analogues (GnRH-a) prior to endometrial ablation has been reported to increase the success rate, as well as to reduce the menstrual blood flow, accounting for a...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000052847
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To investigate the incidence of glucose intolerance postpartum in women with gestational diabetes (GDM) and assess body weight, cholesterol and triglyceride concentrations after delivery. METHODS:This was a study of an initial cohort of 100 women with GDM who were tested at 6 weeks, 6 months, and 1 year post...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000331652
更新日期:2012-01-01 00:00:00
abstract::The etiology of preeclampsia (PE) is unknown, but endothelial cell injury plays a pivotal role. Moreover, there is a significantly positive association between PE and later hypertension. Apolipoprotein J (apo J) plays an important role in stabilizing cell membranes at diverse fluid-tissue interfaces and might protect ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000086056
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To analyze the effects and potential benefits of a single midcycle dose of follicle-stimulating hormone (FSH) prior to human chorionic gonadotropin (hCG) administration during unstimulated in vitro fertilization (IVF) cycles. METHODS:Twenty-five cycles from 20 patients receiving 150 IU of FSH 42-44 h and 10,00...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291825
更新日期:1997-01-01 00:00:00
abstract::In the present study we have measured the concentrations of interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) in preovulatory follicular fluid (FF) samples obtained from patients undergoing ovulation induction with human menopausal gonadotropin/human chorionic gonadotropin. In 13 of the 24 (54...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294853
更新日期:1992-01-01 00:00:00
abstract::Therapeutic abortion by vacuum aspiration in the first trimester was carried out on 129 healthy multigravid women. The loss of haemoglobin at operation was estimated and the volume of blood calculated. The figures were compared to those in a group of primigravid women earlier reported. Blood loss increases with gestat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000300997
更新日期:1978-01-01 00:00:00
abstract::Acupuncture treatment in the final weeks of pregnancy has been claimed to shorten the duration of labor in primiparous women. In the present study, the length of the various phases of labor was calculated for 56 primiparous women who were repeatedly treated with manual acupuncture during the month prior to parturition...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298806
更新日期:1987-01-01 00:00:00
abstract::Our objective was to compare ophthalmic artery pulsatility index values from normal pregnant women with those from preeclampsia patients. The ophthalmic artery of 20 normotensive pregnant women, 7 mildly preeclamptic and 2 severely preeclamptic patients was studied once with color Doppler flow imaging and pulsed Doppl...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292298
更新日期:1995-01-01 00:00:00
abstract::The nuclear DNA content of 20 anembryonic pregnancies was studied by flow cytometry from paraffin embedded tissue blocks. An abnormal amount of DNA content was found in 8 of the cases. This was a significantly higher percentage than encountered in spontaneous abortions studied by the same population (40 and 9%, respec...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000010149
更新日期:1999-01-01 00:00:00
abstract::Serum profiles of growth hormone (GH) were recorded for 24 h in 9 young healthy women before and during treatment with monophasic, combined contraceptives. During treatment, there was a change in GH secretion towards a pattern of smaller peaks at a higher frequency. The mean peak amplitude decreased from 11.2 to 7.3 m...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293276
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Multiple malignancies of the urogenital tract have been reported. We investigated the etiological role of human papillomavirus (HPV) in the pathogenesis of urogenital cancers. CASE:We present a case of cervical squamous carcinoma in a 64-year-old woman who subsequently developed Bowen's disease in the peria...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000097139
更新日期:2007-01-01 00:00:00
abstract::The measurement of the tissue concentrations of cyclic adenosine monophosphate (cAMP) in human endometrium shows that the levels of the nucleotide vary during the menstrual cycle, being 11.4 +/- (SE) 2.5 and 37.7 +/- (SE) 10.1 pmol/mg protein in the proliferative and secretory phase, respectively. The individual deter...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299076
更新日期:1984-01-01 00:00:00
abstract::The concentrations of atrial natriuretic peptide (ANP) and its presumed second messenger, cyclic guanosine-3',5'-monophosphate (cGMP) were determined in maternal plasma and amniotic fluid. Samples were obtained from normal and pathological pregnancies revealing hydramnios or severe Rh incompatibility between week 16 o...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293311
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:The endometriosis fertility index (EFI) is a novel index for predicting pregnancy after surgery. We investigated the utility of the EFI for predicting the ability to conceive without assisted reproductive technology (ART) treatment after laparoscopic surgery. METHODS:From July 2011 through December 2012, we ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000480454
更新日期:2018-01-01 00:00:00
abstract::There is no current consensus on the best treatment modality for cesarean scar pregnancy (CSP) with favorable reproductive and pregnancy outcome. We treated 3 cases of symptomatic CSP with fetal cardiac activity. The first case underwent laparoscopic repair at 6 weeks' gestational age of unruptured CSP. The second pat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000364867
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To compare the maternal and perinatal outcome of nulliparous women 35 years and older at the time of delivery with nulliparous women 25-29 years old. METHODS:A retrospective review of maternal and newborn records of singleton gestations only for first birth in women aged 35 and older (study group n = 143) we...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000064689
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the influence on fertility and pregnancy outcome in cervical intraepithelial neoplasia (CIN) patients after a loop electrosurgical excision procedure (LEEP) or cold-knife conization (CKC). METHODS:269 patients with CIN-II-III who wanted to conceive were prospectively ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,随机对照试验
doi:10.1159/000360538
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To investigate the clinical and prognostic significance of human papillomavirus (HPV) in a Chinese population of cervical cancers. METHODS:We studied 121 cervical cancer tissue samples from patients treated at our hospital. Identification and typing of HPV were done by polymerase chain reaction (PCR) using c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052925
更新日期:2001-01-01 00:00:00
abstract::Digoxin-like immunoreactive substance (DLIS) has been proposed to have a role in what seems to be the timely onset of labor. The relationship between the DLIS in patients with preterm labor and the success of tocolytic therapy with ritodrine and nifedipine has been studied. Using a commercially available radioimmunoas...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292511
更新日期:1994-01-01 00:00:00
abstract::Hot flushes are the commonest symptom induced by gonadotropin-releasing hormone agonists (GnRHa). We performed an open observational trial to evaluate the efficacy of veralipride, an antidopaminergic drug, in reducing hot flushes in 25 premenopausal women treated with a GnRHa for endometriosis (8 subjects) or menorrha...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000292736
更新日期:1992-01-01 00:00:00
abstract::The possibility to predict a large infant during pregnancy was assessed using data from a prospective cohort study of 537 singleton pregnancies with term deliveries. Maternal characteristics, symphysis fundal height and ultrasound measurements were used in multivariate analyses for the prediction of an infant with a b...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292658
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Single-port laparoscopy (LESS) utilizes a single, multichannel port in an attempt to decrease postoperative pain, while enhancing cosmesis and minimizing the potential risks and morbidities associated with the multiple ports used in conventional laparoscopy. METHODS:We performed a retrospective study examin...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000367659
更新日期:2015-01-01 00:00:00
abstract::We report an extremely rare case of a 50-year-old woman with an adenocarcinoma arising within a urethral diverticulum. She could not be diagnosed correctly before operation and the microscopic pathological examination of the surgical specimen was the only indication showing the cancer origin. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292307
更新日期:1995-01-01 00:00:00
abstract::Lipid peroxidation and the antioxidant system were investigated in the plasma and placenta of normal and preeclamptic pregnant women. A significant increase in thiobarbituric acid reactive substance (TBARS), significant decreases in total thiol (t-SH) content and superoxide dismutase (SOD) activity, and unchanged vita...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009994
更新日期:1998-01-01 00:00:00
abstract::Among angiogenic factors, VEGF secreted from activated macrophages under the influence of ovarian steroids, IL-8 expressed in endometrial stromal cells, and basic FGF expressed in endometriotic tissue and PD-ECGF expressed in lining epithelial cells independently of the sex steroidal milieu might contribute to the cha...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000052864
更新日期:1999-01-01 00:00:00
abstract::This is a descriptive and cross-sectional study aiming to determine the factors affecting sexual life in pregnant women. The study was carried out in 238 women in Malatya, Turkey. It was found that 61.4% regarded coitus as a risk during pregnancy, 31.9% did not have any knowledge about this matter. In 81.5% sexual lif...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000075582
更新日期:2004-01-01 00:00:00
abstract::Progesterone secretion of cultured human granulosa cells treated with LHRH or its analogues was measured. Granulosa cells were also stimulated with LH, FSH, cAMP or forskolin. No differences could be observed in the progesterone basal secretion of cultures treated with or without LHRH or its analogues and after the va...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292765
更新日期:1992-01-01 00:00:00
abstract::Oviducts of 35 mature, white New Zealand rabbits were injured by a laser beam, using various powers from 25 to 40 W, and by a series of pulses of 1/10, 1/20 or 1/100 s duration. The contralateral oviducts served as controls and were injured at similar areas by a scalpel. The injured areas of both tubes were histologic...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299610
更新日期:1981-01-01 00:00:00
abstract:AIM:The aim of this study was to evaluate whether natural fertility is related to serum 25-hydroxyvitamin D (25-OH-vitamin D) levels. METHODS:A nested case-control study was designed from a prospective cohort of pregnant women undergoing first trimester screening for aneuploidies. Cases included women seeking pregnanc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000443397
更新日期:2016-01-01 00:00:00