Veralipride for hot flushes during gonadotropin-releasing hormone agonist treatment.

Abstract:

:Hot flushes are the commonest symptom induced by gonadotropin-releasing hormone agonists (GnRHa). We performed an open observational trial to evaluate the efficacy of veralipride, an antidopaminergic drug, in reducing hot flushes in 25 premenopausal women treated with a GnRHa for endometriosis (8 subjects) or menorrhagia (17 subjects). The patients received goserelin depot for 6 months and veralipride was added for the third month. Hot flushes, severe in all women at 2 months, improved in both frequency and intensity in 92% of the subjects during veralipride administration. The benefit obtained persisted until the end of the GnRHa treatment.

journal_name

Gynecol Obstet Invest

authors

Vercellini P,Vendola N,Colombo A,Passadore C,Trespidi L,Crosignani PG

doi

10.1159/000292736

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

102-4

issue

2

eissn

0378-7346

issn

1423-002X

journal_volume

34

pub_type

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