Is There Any Relationship between Plasma Pentraxin 3 Levels and Gestational Diabetes Mellitus?

Abstract:

BACKGROUND:Pentraxin 3 (PTX3) is a novel vascular inflammatory marker which increases in vascular events such as diabetes mellitus. The aim of this study was to investigate the relationship between serum PTX3 levels and gestational diabetes mellitus (GDM). METHODS:This prospective observational study was comprised of 88 pregnant women with singleton pregnancies. The subjects were classified into 3 groups according to their response to a 50-gram glucose challenge test (GCT) and a 100-gram oral glucose tolerance test: control group (n = 28), impaired glucose tolerance group (n = 30), and GDM group (n = 30). Serum PTX3 levels were measured to examine the relationship between GDM and GCT values. RESULTS:Significant differences in PTX3 levels were observed among the 3 groups in the sample (F = 7.598; p = 0.001). The mean PTX3 value was found to be significantly higher in the GDM group (3.17 ± 1.16 ng/ml) than in the control group (2.20 ± 0.83 ng/ml; p = 0.001). A significant positive correlation between PTX3 and GCT values was detected (r = 0.289; p = 0.008). CONCLUSION:Maternal serum PTX3 levels were found to be significantly related to high blood glucose levels. This may be an indicator of vascular pathology in GDM around the time of an oral glucose tolerance test.

journal_name

Gynecol Obstet Invest

authors

Yildirim M,Simavli SA,Uysal Derbent A,Kaygusuz I,Uysal S

doi

10.1159/000373889

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

223-7

issue

4

eissn

0378-7346

issn

1423-002X

pii

000373889

journal_volume

80

pub_type

杂志文章
  • Effect of danazol and ovariectomy on matrix metalloproteinases in rat uteri.

    abstract::The experiments described in this report were designed to study the effects of danazol on matrix metalloproteinases in the rat uterus. Proteinases were analyzed by zymography in gels copolymerized with either gelatin or transferrin. There were no apparent effects of danazol on proteinases from rat uteri when analyzed ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010218

    authors: Willingham AK

    更新日期:2000-01-01 00:00:00

  • Diagnostic Relevance of Ferrokinetic Laboratory Markers in Anemic Pregnant Women.

    abstract:OBJECTIVES:Different forms of anemia are considered as the most frequent complication of the gestational period. By its etiology, pathogenesis, and clinical hematology, it is not a single disease. Among all forms of anemia occurring during pregnancy, iron deficiency anemia (IDA) is the most common, accounting for 80-95...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000511018

    authors: Aringazina R,Zharmakhanova G,Kurmanalina G,Bekkuzhin A,Kurmanalin B

    更新日期:2020-01-01 00:00:00

  • Role of T-cell cytokines in decidua and in cumulus oophorus during pregnancy.

    abstract::We focus on the roles of decidual and cumulus oophorus T cells. It was suggested that Th1-type cytokines (IFN-gamma and TNF-beta), which promote allograft rejection, may compromise pregnancy, whereas the Th2-type cytokines (IL-4, IL-5, IL-10) inhibiting the Th1 responses promote allograft tolerance and therefore may i...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,评审

    doi:10.1159/000101738

    authors: Piccinni MP

    更新日期:2007-01-01 00:00:00

  • Diagnostic aid of endometrium biopsy.

    abstract::The 784 cases, from which 701 complained of abnormal uterine bleeding, were reviewed by age groups, presenting symptoms, sex steroid medication and endometrial findings. Endometrial polyps and endometritis, which showed an incidence of 17.5 and 10.0%, respectively, were correlated with clinicopathologic findings. Peri...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299980

    authors: van Bogaert LJ

    更新日期:1979-01-01 00:00:00

  • Treatment of metastatic uterine leiomyosarcoma with cisplatin, pirarubicin, and ifosfamide.

    abstract::We present the unusual case of a 27-year-old Japanese woman who exhibited recurrences of metastatic tumors from uterine leiomyosarcoma after five operations. Chemotherapy with cisplatin, pirarubicin, and cyclophosphamide was ineffective. Substituting ifosfamide for cyclophosphamide, we obtained a complete response. Th...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291415

    authors: Hirota Y,Miyamura K,Hayata T,Miyakawa I

    更新日期:1997-01-01 00:00:00

  • Endometrial metastasis from breast cancer in a patient receiving tamoxifen therapy.

    abstract::Tamoxifen (TAM) is known to be associated with several types of endometrial pathologies, e.g. hyperplasias, polyps and endometrial carcinomas, sometimes of special histologic type. Here we report a rare case of endometrial metastasis from a breast carcinoma (ductal carcinoma) discovered during TAM therapy. This occurr...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010299

    authors: Horn LC,Einenkel J,Baier D

    更新日期:2000-01-01 00:00:00

  • Metastatic choriocarcinoma presenting in a gravid woman.

    abstract::Choriocarcinoma coexistent with an intrauterine pregnancy is rare and requires decisions affecting mother and child to treat this aggressive tumor. An instance of this situation is presented to highlight clinical circumstances that warrant departure from accepted dogma. Pathologic aspects of choriocarcinoma are also d...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000363234

    authors: Byrd K,Seay R,Bechert CJ,Maxwell GL,Bicher A

    更新日期:2015-01-01 00:00:00

  • Effect of membrane sweeping at term pregnancy on duration of pregnancy and labor induction: a randomized trial.

    abstract:AIM:To evaluate the efficacy of sweeping of fetal membranes for induction of labor in uncomplicated term pregnancies. METHODS:A randomized controlled trial was performed in 122 pregnant women beyond 39 weeks of gestation with no complications. The women were assigned to have their membranes swept or not (controls) for...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000091842

    authors: Kashanian M,Akbarian A,Baradaran H,Samiee MM

    更新日期:2006-01-01 00:00:00

  • Estrogen-producing ovarian adenocarcinoma with large abscess formation.

    abstract::We report a postmenopausal patient with serous papillary cystadenocarcinoma of the ovary associated with large abscess formation and estrogen production. Ovarian cancer accompanied by stromal function is an occasional event, but large abscess association is a rarity. The present case is thus even rarer. Her clinical c...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292710

    authors: Yoshida M,Katsuragawa H,Miyamoto U,Ohnishi S,Katsura Y

    更新日期:1993-01-01 00:00:00

  • The shape and dimensions of the human vagina as seen in three-dimensional vinyl polysiloxane casts.

    abstract::Full vaginal casts of 39 caucasian women, 13 each nulliparous, uniparous and multiparous, were made using vinyl polysiloxane impression material. Vaginal lengths were measured with polished acrylic rods inserted by the subjects, and introital diameters were measured with conical polypropylene flasks. Parallel sided, c...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291946

    authors: Pendergrass PB,Reeves CA,Belovicz MW,Molter DJ,White JH

    更新日期:1996-01-01 00:00:00

  • Correlating the accuracy of colposcopy with practitioner experience when diagnosing cervical pathology using the dynamic spectral imaging system.

    abstract:BACKGROUND/AIMS:To assess the performance of colposcopists and correlate it with their experience when diagnosing cervical pathology by reviewing conventional colposcopy (CC) digital images and the Dynamic Spectral Imaging System (DySIS) cervical map. METHODS:Images from 50 women with normal and abnormal cervix collec...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000365087

    authors: Coronado PJ,Fasero M

    更新日期:2014-01-01 00:00:00

  • Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy.

    abstract::The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine. After intravenous administration of 18.5 MBq (0.5 mCi) 113mIn, the gamma radiation emanating from the placenta was recorded with a computer-linked gamma camera during 10-se...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299279

    authors: Lunell NO,Lewander R,Nylund L,Sarby B,Thornström S

    更新日期:1983-01-01 00:00:00

  • Hypoxia represses the differentiation of Rcho-1 rat trophoblast giant cells.

    abstract:BACKGROUND:A hypoxic environment is known to be essential for early placentation. A low oxygen tension induces hypoxia-inducible factor-1 (HIF-1alpha) which may play an important role as a transcription factor in maintaining the proliferative and undifferentiated phenotype in human trophoblasts. METHODS:We analyzed th...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000097634

    authors: Takeda T,Sakata M,Isobe A,Yamamoto T,Nishimoto F,Minekawa R,Okamoto Y,Tasaka K,Murata Y

    更新日期:2007-01-01 00:00:00

  • Conventional and computerized antepartum telecardiotocography. Experienced and inexperienced observers versus computerized analysis.

    abstract::The study assessed the agreement in cardiotocogram interpretation between the 2CTG computerized system and experienced and inexperienced observers involved in a telecardiotocography project called 'TOCOMAT'. Both observers and computer analyzed FHR baseline, FHR variability, and number of large accelerations and of de...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000068955

    authors: Di Lieto A,Giani U,Campanile M,De Falco M,Scaramellino M,Papa R

    更新日期:2003-01-01 00:00:00

  • MIB 1 immunostaining in cervical intraepithelial neoplasia: prognostic significance in mild and moderate lesions.

    abstract:OBJECTIVE:MIB 1 is a new monoclonal antibody which recognizes nuclei of proliferating cells throughout the cell cycle except during the G0 and early G1 phases. In the present study we analyzed the MIB 1 immunostaining as an index of cellular proliferation in cervical intraepithelial neoplasia (CIN) and microinvasive ca...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291977

    authors: Garzetti GG,Ciavattini A,De Nictolis M,Lucarini G,Goteri G,Romanini C,Biagini G

    更新日期:1996-01-01 00:00:00

  • Immunoradiometric studies with a monoclonal antibody against an estrogen-receptor-related protein in human breast cancer.

    abstract::The concentration of P29, a phosphoprotein related to estradiol receptor (RE), was measured by an immunoradiometric assay in human breast cancer cytosol and the results compared with the levels of RE and progesterone receptors (RP), as measured by the classical ligand-binding assay. Good linear correlation was found b...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293689

    authors: Cano A,Rivera J,Parrilla JJ,Abad L

    更新日期:1988-01-01 00:00:00

  • Dystroglycan in human fetal membranes decreases in later gestation and with spontaneous membrane rupture.

    abstract:BACKGROUND/AIMS:The transmembrane protein dystroglycan (DG) is known to anchor the cell membrane to the extracellular matrix, and is susceptible to cleavage by matrix metalloproteinases. This study tested the hypothesis that changes in DG abundance in fetal membranes (FM) occur late in gestation, with spontaneous ruptu...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000367894

    authors: Theiler RN,Snyder RR,Theiler SK

    更新日期:2015-01-01 00:00:00

  • Magnetic resonance-visible polypropylene mesh for pelvic organ prolapse repair.

    abstract:AIM:To develop a magnetic resonance (MR)-visible mesh using iron oxides and prove visibility. METHODS:In a phantom study, a suitable iron oxide, Fe3O4 [iron(II,III) oxide] and FeOOH [iron(III) oxide-hydroxide], concentration was determined using relaxometric MR measurements of the transverse relaxation rates R2 and R2...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000366442

    authors: Brocker KA,Lippus F,Alt CD,Hallscheidt P,Zsolt F,Soljanik I,Lenz F,Bock M,Sohn C

    更新日期:2015-01-01 00:00:00

  • Guillain-barré syndrome in pregnancy: early diagnosis and treatment is essential for a favorable outcome.

    abstract::Guillain-Barré syndrome (GBS) is an acute or subacute demyelinating polyneuropathy that rarely complicates pregnancy, but increases maternal and perinatal morbidity. A 15-year-old pregnant woman was admitted with ascending paralysis and acellular lumbar puncture suggestive of GBS. She required mechanical ventilation f...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000209215

    authors: Campos da Silva F,de Moraes Paula G,Dos Santos Esteves Automari CV,Mendes de Almeida DS,Ubirajara Cavalcanti Guimarães R

    更新日期:2009-01-01 00:00:00

  • Mucin-like carcinoma-associated antigen serum levels in patients with adenocarcinomas originating from ovary, breast and colon.

    abstract::The mucin-like carcinoma-associated antigen (MCA) enzyme immunoassay was tested in 962 healthy controls. MCA levels were compared with CA 125 in 70 patients with benign and 76 with malignant ovarian tumors. In addition MCA was compared with CA 15.3 in 58 patients with breast cancer and with CEA in 50 patients with col...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291890

    authors: Bon GG,Verheijen RH,Zuetenhorst JM,van Kamp GJ,Verstraeten AA,Kenemans P

    更新日期:1996-01-01 00:00:00

  • Side effects of tamoxifen in oophorectomized rats.

    abstract:OBJECTIVE:Our objective was to evaluate the direct effect of tamoxifen citrate (TAM) on the endometrium, liver, breast tissue and the lipid profile in oophorectomized (OX) rats. STUDY DESIGN:An experimental animal study. MATERIAL AND METHODS:Forty-one mature rats (33 OX) were randomly divided into four groups and rec...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000009933

    authors: Kafkasli A,Erdem F,Müezzinoglu B,Akbaşak B,Burak F,Aksoy T,Birincioglu M,Biotech MG,Biotec FT

    更新日期:1998-01-01 00:00:00

  • Impaired mixed lymphocyte reaction in intrahepatic cholestasis of pregnancy.

    abstract:OBJECTIVE:To clarify the alteration of maternal-fetal mixed lymphocyte reaction (MLR) in intrahepatic cholestasis of pregnancy (ICP). METHODS:Twenty-two patients with intrahepatic cholestasis of pregnancy and 21 normal pregnant women were recruited into the present study. Of patients with ICP, 5 also experienced pregn...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000068381

    authors: Dong M,Xie X,Wang Z,He J,Zhou J,Cheng Q

    更新日期:2002-01-01 00:00:00

  • Efficacy of ER-alpha polymorphisms and the intrafollicular IGF system for predicting pregnancy in IVF-ET patients.

    abstract:AIMS:To evaluate the efficacies of the estrogen receptor-alpha (ER-alpha) gene polymorphisms and of the intrafollicular insulin-like growth factor (IGF) system for predicting pregnancy in in vitro fertilization and embryo transfer (IVF-ET) patients. METHODS:A total of 96 patients undergoing IVF-ET were included in thi...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000162104

    authors: Choi YS,Kim SH,Ku SY,Jee BC,Suh CS,Choi YM,Kim JG,Moon SY

    更新日期:2009-01-01 00:00:00

  • Altered growth hormone secretion during oral contraception.

    abstract::Serum profiles of growth hormone (GH) were recorded for 24 h in 9 young healthy women before and during treatment with monophasic, combined contraceptives. During treatment, there was a change in GH secretion towards a pattern of smaller peaks at a higher frequency. The mean peak amplitude decreased from 11.2 to 7.3 m...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293276

    authors: Karlsson R,Edén S,von Schoultz B

    更新日期:1990-01-01 00:00:00

  • Mixed clear cell and endometrioid carcinoma arising in parietal endometriosis.

    abstract:AIM:We report a case of a mixed clear cell and endometrioid carcinoma arising in parietal endometriosis. METHODS:A 46-year-old woman presented a second recurrence of parietal endometriosis. An extensive surgical resection of the tumor was then carried out. RESULTS:Histological analysis revealed heterogeneous tissues ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000096437

    authors: Razzouk K,Roman H,Chanavaz-Lacheray I,Scotté M,Verspyck E,Marpeau L

    更新日期:2007-01-01 00:00:00

  • Uterine intravascular fetal material and coagulopathy at peripartum hysterectomy.

    abstract:BACKGROUND/AIMS:To test the hypothesis that obstetrical disseminated intravascular coagulopathy results from an excessive leakage of fetal material into the maternal circulation. METHODS:All peripartum hysterectomy cases for hemorrhage at two suburban Illinois hospitals over 10 years were included. Intravascular prese...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000332373

    authors: Benson MD,Cheema N,Kaufman MW,Goldschmidt RA,Beaumont JL

    更新日期:2012-01-01 00:00:00

  • Patient satisfaction after laparoscopic total or supracervical hysterectomy.

    abstract:BACKGROUND/AIMS:To evaluate patient satisfaction after laparoscopic supracervical (LASH) or total hysterectomy (TLH). METHODS:Retrospective study of patient satisfaction after LASH or TLH. RESULTS:We studied 40 cases of LASH and another 40 of TLH. The age of the patients, marital status, education level and employmen...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000184679

    authors: Kafy S,Al-Sannan B,Kabli N,Tulandi T

    更新日期:2009-01-01 00:00:00

  • Serum angiogenin levels during menstrual cycle and pregnancy.

    abstract:OBJECTIVE:To evaluate alterations in maternal circulating angiogenin levels with advancing gestation and to assess the effect of labor stress on serum angiogenin levels in neonates delivered vaginally and by cesarean section. METHODS:The maternal circulating angiogenin concentrations were compared in 37 normotensive n...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010270

    authors: Hayashi K,Yanagihara T,Hata T

    更新日期:2000-01-01 00:00:00

  • Novel Nonsense Mutation in the NLRP7 Gene Associated with Recurrent Hydatidiform Mole.

    abstract:AIM:This study aimed to clarify the genetic and epigenetic features of recurrent hydatidiform mole (RHM) in Japanese patients. METHODS:Four Japanese isolated RHM cases were analyzed using whole-exome sequencing. Villi from RHMs were collected by laser microdissection for genotyping and DNA methylation assay of differe...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000441780

    authors: Ito Y,Maehara K,Kaneki E,Matsuoka K,Sugahara N,Miyata T,Kamura H,Yamaguchi Y,Kono A,Nakabayashi K,Migita O,Higashimoto K,Soejima H,Okamoto A,Nakamura H,Kimura T,Wake N,Taniguchi T,Hata K

    更新日期:2016-01-01 00:00:00

  • Chronic intrauterine bleeding and fetal growth at less than 32 weeks of gestation.

    abstract::Placental hemosiderin deposition representing intrauterine bleeding at least 24-48 h before delivery is detected frequently in prematurity. The objective of this study was to assess incidence and site of histologic evidence of intrauterine bleeding in association with fetal growth in prematurity. Placentas of consecut...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010289

    authors: Sherer DM,Salafia CM

    更新日期:2000-01-01 00:00:00