Abstract:
:In 8 fetal sheep under anesthesia, we examined the relationship between the fetal aorta blood flow velocity waveform and fetal mean arterial pressure after administration of norepinephrine and angiotensin II. It was hypothesized that the pulsatility index (PI) of the waveform would change during fetal hypertension. Measurements were performed using a 20-MHz Doppler transducer on the aorta directly beneath the diaphragm and a catheter inserted via the femoral artery into the abdominal aorta. Further instrumentation included a Doppler transducer and an electromagnetic flowmeter on the common umbilical artery and a catheter in the inferior vena cava. Fetal hypertension was induced by bolus administration of either norepinephrine or angiotensin II or by infusion of norepinephrine. With the Doppler transducer on the common umbilical artery, it was possible to study external iliac artery blood velocity waveforms in 4 fetal lambs, whereas aorta blood velocity waveforms were recorded in 7 fetal lambs. The measurements of external iliac artery PI and mean arterial pressure were characterized by a linear regression with a correlation coefficient of 0.72, whereas the measurements of aorta PI and mean arterial blood pressure were characterized by a linear regression with a correlation coefficient of 0.40. However, notable changes were observed in the aorta blood velocity waveform, which were not expressed by a substantial increase in the aorta PI. These changes can be described as a narrowing of the systolic peak and an earlier occurrence of the first dicrotic notch.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Muijsers GJ,van Huisseling H,Hasaart THdoi
10.1159/000292583subject
Has Abstractpub_date
1993-01-01 00:00:00pages
1-7issue
1eissn
0378-7346issn
1423-002Xjournal_volume
36pub_type
杂志文章abstract:OBJECTIVE:To compare the maternal and perinatal outcome of nulliparous women 35 years and older at the time of delivery with nulliparous women 25-29 years old. METHODS:A retrospective review of maternal and newborn records of singleton gestations only for first birth in women aged 35 and older (study group n = 143) we...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000064689
更新日期:2002-01-01 00:00:00
abstract:AIM:The aim of the study was to compare the effectiveness of dienogest (DIE), depo medroxyprogesterone 17-acetate (MPA), and micronized progesteron (MP) regimens for treatment of simple endometrial hyperplasia (EH) without atypia. METHODS:One hundred and twenty premenopausal patients aged between 35 and 55, with simpl...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,随机对照试验
doi:10.1159/000477618
更新日期:2018-01-01 00:00:00
abstract::We present the case of a female fetus aborted in the 20th week of gestation due to severely dysplastic kidneys, anhydramnios and hydranencephalus. The combination of these malformations is extremely rare, resulting in only 4 cases described so far. Our case is the first ever presented in a female showing polycystic-dy...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000291522
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to investigate the in vivo magnetic resonance spectroscopy features of uterine leiomyomas using long echo time and to characterize the spectral patterns of these lesions. METHODS:We calculated metabolites in 15 patients with uterine leiomyomas and myometrium of 20 healthy control...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000080020
更新日期:2004-01-01 00:00:00
abstract::The morphological effect of a high-dose progestogen (Depo-Provera) on highly differentiated endometrial carcinoma was studied. Thirteen patients were treated by progestogen only, given at the beginning of the treatment in a weekly dose of 1,000 mg for 3 month. Then, progestogen 500 mg was administered for 12 months. N...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298812
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:The aim of this prospective study was to evaluate (18)F-FDG-PET, in comparison with CT, for the detection of peritoneal and retroperitoneal metastases of ovarian cancer. METHODOLOGY:13 patients with primary (n = 7) or recurrent (n = 6) ovarian cancer underwent an attenuation-corrected (18)F-FDG-PET of the ab...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000071525
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:Isotretinoin is used in acne vulgaris treatment for more than 20 years. Isotretinoin has serious side effects on many organs, but there are no comprehensive studies investigating its possible toxic effects on reproductive organs. Thus, we aimed to investigate the possible toxic effects of isotretinoin adminis...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000510031
更新日期:2020-01-01 00:00:00
abstract::The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine. After intravenous administration of 18.5 MBq (0.5 mCi) 113mIn, the gamma radiation emanating from the placenta was recorded with a computer-linked gamma camera during 10-se...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299279
更新日期:1983-01-01 00:00:00
abstract::The relationship between contraction changes and cAMP production under long-term application of ritodrine was investigated using longitudinal muscle strips of pregnant (Day 21) rat uterus. Cellular cAMP gradually increased up to 20 min, then decreased to the control level and fluctuated after 90 min in the presence of...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293119
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:To review the literature and compare detection rates, false negative (FN) rates, and negative predictive values (NPVs) of sentinel lymph node (SLN) biopsy in endometrial cancer to those in breast and vulvar cancer. Secondary objectives were to evaluate techniques of SLN biopsy in endometrial cancer. ME...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000353897
更新日期:2013-01-01 00:00:00
abstract::By means of bacteriological, histological and immunofluorescence methods, the ascending spread of endocervically inoculated bacteria was studied in 14 pregnant sheep. 8 ewes near term were exposed to group B streptococci, Bacteroides fragilis or Streptococcus intermedius for 2-4 days. 6 other animals in mid pregnancy ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299415
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND/AIMS:Dyslipidemia is common in women with polycystic ovary syndrome (PCOS) irrespective of age. Our aim was to investigate soluble tumor necrosis factor like weak inducer of apoptosis (sTWEAK), a cardiovascular risk marker in PCOS, and to determine if it is associated with dyslipidemia in youth. METHODS:A p...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000447590
更新日期:2017-01-01 00:00:00
abstract::The patterns of plasma melatonin, gonadotropins, sex steroids and prolactin were studied in anovulatory infertile females undergoing ovulation induction with hMG/hCG. Melatonin levels were found to fluctuate during the menstrual cycle of these subjects with a nadir at mid-cycle and peak occurring at the early follicul...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009977
更新日期:1998-01-01 00:00:00
abstract::We report an extremely rare case of a 50-year-old woman with an adenocarcinoma arising within a urethral diverticulum. She could not be diagnosed correctly before operation and the microscopic pathological examination of the surgical specimen was the only indication showing the cancer origin. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292307
更新日期:1995-01-01 00:00:00
abstract::To evaluate a new reflectance photometer (Accusport) for blood lactate determination, a prospective non-interventional study was performed on blood obtained from the umbilical cord artery immediately after delivery of the baby in 109 consecutive women. For each sample, the results of cord arterial blood lactate values...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009919
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:The aim of this study is to assess the clinical effectiveness and safety of hyaluronic acid gel for the prevention of postoperative intrauterine adhesions (IUAs). METHODS:PubMed, Cochrane Library, Embase and ClinicalTrials.gov databases were searched for randomized controlled trials. RESULTS:Six RCTs with ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,meta分析
doi:10.1159/000486674
更新日期:2018-01-01 00:00:00
abstract:AIMS:The study aimed to assess the diagnostic value of serial monitoring of biochemical inflammatory markers (C-reactive protein (CRP) and white blood cell (WBC) count) in the postoperative diagnosis of anastomotic leakage or ureteral injury after bowel resection for deep infiltrating endometriosis. METHODS:This is a ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000447513
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To evaluate alterations in maternal circulating angiogenin levels with advancing gestation and to assess the effect of labor stress on serum angiogenin levels in neonates delivered vaginally and by cesarean section. METHODS:The maternal circulating angiogenin concentrations were compared in 37 normotensive n...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010270
更新日期:2000-01-01 00:00:00
abstract::Uterine leiomyomas are the most common tumors of the genital tract. Growth factors seem to be implicated in the development of leiomyoma. The aim of this study was to determine insulin-like growth factor 1 receptor (IGF-1-R) mRNA levels and IGF-1-R tyrosine kinase activity in normal myometrium and leiomyoma. Plasma me...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000076690
更新日期:2004-01-01 00:00:00
abstract::Amniotic fluids from women in West Virginia were evaluated for the presence of antibacterial activity by a bioassay technique. 41% of 32 third trimester samples were inhibitory. Evaluation of additional test organisms emphasized differences in susceptibility of various bacterial strains; two isolates of Escherichia co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299390
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Pentraxin 3 (PTX3) is a novel vascular inflammatory marker which increases in vascular events such as diabetes mellitus. The aim of this study was to investigate the relationship between serum PTX3 levels and gestational diabetes mellitus (GDM). METHODS:This prospective observational study was comprised of ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000373889
更新日期:2015-01-01 00:00:00
abstract::The effect of the moon on the number of newborns has been investigated extensively with contradictory results but with few significant findings. In this paper, a possible lunar effect is analyzed by a nonlinear Poisson regression model similar to a Fourier analysis based on all children (n = 2,760,362) born in Austria...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052999
更新日期:2002-01-01 00:00:00
abstract:AIMS:The study aimed to compare the clinical course and disease severity between culture positive and culture negative patients with intra-uterine devices (IUD)-associated pelvic inflammatory disease (PID). METHODS:A retrospective study of all IUD-associated PID patients admitted to tertiary medical center between 201...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000490666
更新日期:2019-01-01 00:00:00
abstract::A 29-year-old woman presented with preterm labour at 32 weeks of gestation. Tocolytic treatment was started with intravenous hexoprenaline. Twenty-four hours after initiation of treatment, the patient developed supraventricular tachycardia, resistant to digoxin and verapamil. Medical treatment with metoprolol finally ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292411
更新日期:1995-01-01 00:00:00
abstract::We treated a patient with an ovarian tumor histologically consisting of an endometrial cyst, dermoid cyst and mucinous cystadenoma, in the same ovary. A comparative study between ultrasonic and histological findings was done. The usefulness, drawbacks and limitations in the ultrasonic evaluation of ovarian tumors are ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293646
更新日期:1989-01-01 00:00:00
abstract::Prophylactic antibiotic therapy is accepted for prevention of postceasarean infection in certain risk groups. Of the antibiotic regimens presented none appears superior. Patients having a cesarean section (CS) more than 6 h after membrane rupture were given three doses of cefuroxime (1.5 g every 8th hour) in a prospec...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293492
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND/AIMS:A phase II study was conducted to assess the activity and toxicity of weekly docetaxel in patients with advanced or recurrent cancer of the cervix. METHODS:Eligible patients were required to have measurable disease with adequate performance status, bone marrow, renal and hepatic function. Patients were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000106489
更新日期:2007-01-01 00:00:00
abstract::Serum samples were collected from 199 patients attending a gynaecological clinic, colposcopy specimens being taken at the same time for routine pathology of paraffin sections which ranged from normal, through the degrees of dysplasia to carcinoma in situ. Other parameters noted were age, number of pregnancies and time...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299470
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To evaluate whether prolactin, alpha-fetoprotein (AFP) or B-human chorionic gonadotropin (BHCG) is the most effective marker in vaginal fluid for diagnosing prelabor rupture of membranes (PROM). These proteins are present in amniotic and vaginal fluid and have been reported to be potent markers of PROM, but h...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000097844
更新日期:2007-01-01 00:00:00
abstract::We report a case of an unusual vesicovaginal stone. The dumb-bell-shaped stone created a ball valve effect in the fistula, therefore giving rise to only mild urinary leakage despite the large size of the fistula. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000064686
更新日期:2002-01-01 00:00:00