Lack of association of cytomegalovirus antibody level with carcinoma of the uterine cervix.

Abstract:

:Serum samples were collected from 199 patients attending a gynaecological clinic, colposcopy specimens being taken at the same time for routine pathology of paraffin sections which ranged from normal, through the degrees of dysplasia to carcinoma in situ. Other parameters noted were age, number of pregnancies and time since last pregnancy. When level of antibody to cytomegalovirus in each serum sample was tested by ELISA, anti-complement immunofluorescence and neutralisation, no correlation was found between antibody titre and pathological diagnosis. The only interdependence seen was that, as the age of the patients increased, so did the frequency of sero-positivity to cytomegalovirus. Also in the group studied the frequency of carcinoma in situ was not age dependent.

journal_name

Gynecol Obstet Invest

authors

Hart H,Springbett A,Norval M

doi

10.1159/000299470

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

300-8

issue

4

eissn

0378-7346

issn

1423-002X

journal_volume

14

pub_type

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