Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy.

Abstract:

:The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine. After intravenous administration of 18.5 MBq (0.5 mCi) 113mIn, the gamma radiation emanating from the placenta was recorded with a computer-linked gamma camera during 10-second intervals for 240 s. From time-activity analysis of the isotope curve a uteroplacental blood flow index could be calculated. 30 min after the intravenous injection of dihydralazine, 18.5 MBq 113mIn were again administered, and a second uteroplacental blood flow index was calculated. After dihydralazine administration there was a significant reduction of mean blood pressure (p less than 0.01) and an increase of mean maternal heart rate (p less than 0.01). There was no significant change in uteroplacental blood flow or in uteroplacental vascular resistance.

journal_name

Gynecol Obstet Invest

authors

Lunell NO,Lewander R,Nylund L,Sarby B,Thornström S

doi

10.1159/000299279

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

274-82

issue

5

eissn

0378-7346

issn

1423-002X

journal_volume

16

pub_type

杂志文章
  • Parity-related prevalence of rhesus antigens among Mozambican parturients.

    abstract::The potential risk of rhesus alloimmunization and the ensuing risk of fetal death with increasing parity were investigated in two groups of parturients; primiparous and grand multiparous (para > or = 5) women with liveborns. It was hypothesized that significantly fewer women of the latter than of the former group woul...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292744

    authors: Pereira C,Axemo P,Bergström S,Säfwenberg J

    更新日期:1992-01-01 00:00:00

  • Comparison of the long-term effects of estrogen and clomiphene citrate on pituitary and uterine function in ovariectomized rats.

    abstract::The effects of estradiol-17 beta (E2) and clomiphene citrate (CC) on pituitary-uterine function in ovariectomized (OVX) rats were compared in two experiments. In experiment 1, CC completely blocked E2 stimulation of uterine weight when administered concurrently for 10 and 30 days. In experiment 2, content of total (oc...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293095

    authors: Brown JL,Byrd SJ,Mitchell AS,Nelson MF,Young RL,Chakraborty PK

    更新日期:1991-01-01 00:00:00

  • Maternal blood distribution of zinc and copper during labor and after delivery.

    abstract::In 15 normal mothers the stress effects of labor on zinc and copper distributions in erythrocytes and plasma were investigated. Lower levels of total zinc and of zinc derived from both carbonic anhydrase isoenzymes (CA-I and CA-II), especially from CA-I, in erythrocytes were obtained immediately after delivery. On the...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000298798

    authors: Yamashita K,Ohno H,Kondo T,Kawamura M,Mure K,Yorozu Y,Ishikawa M,Shimizu T,Taniguchi N

    更新日期:1987-01-01 00:00:00

  • Depot medroxy progesterone acetate: a poor preparatory agent for endometrial resection.

    abstract:OBJECTIVE:To evaluate the efficacy of depot medroxy progesterone acetate (DMPA) as a preparatory agent for endometrial resection. STUDY DESIGN:Endometrial resection was performed on 50 women for excessive uterine bleeding. The patients were randomly divided into 2 equal groups, with the first group receiving DMPA and ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000052969

    authors: Kriplani A,Manchanda R,Monga D,Takkar D

    更新日期:2001-01-01 00:00:00

  • Bacteroides fragilis, Streptococcus intermedius and group B streptococci in ascending infection of pregnancy. An animal experimental study.

    abstract::By means of bacteriological, histological and immunofluorescence methods, the ascending spread of endocervically inoculated bacteria was studied in 14 pregnant sheep. 8 ewes near term were exposed to group B streptococci, Bacteroides fragilis or Streptococcus intermedius for 2-4 days. 6 other animals in mid pregnancy ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299415

    authors: Evaldson G,Malmborg AS,Nord CE,Ostensson K

    更新日期:1983-01-01 00:00:00

  • Consecutive pregnancies in a menopausal woman following oocyte donation.

    abstract::A second pregnancy was successfully achieved by a menopausal women who had previously conceived and delivered an infant using donated oocytes. The same nonanonymous oocyte donor provided the gametes for both procedures. Prior to embryo transfer, the functionally agonadal recipient received exogenous steroid hormone re...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293009

    authors: Sauer MV,Paulson RJ

    更新日期:1991-01-01 00:00:00

  • C-myc mutation detected by polymerase chain reaction--heteroduplex in cervical cancer.

    abstract::To evaluate both the incidence of c-myc gene mutation and the relationship of this finding to the clinico-pathologic characteristics of patients with cervical cancer, a polymerase chain reaction (PCR)-based heteroduplex gel electrophoresis method was used to screen DNA extracted from 102 cervical invasive carcinomas r...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291505

    authors: Wong YF,Rogers MS,Cheung TH,Yim SF,Chang AM

    更新日期:1997-01-01 00:00:00

  • Changes in plasma norepinephrine in normal labor following isometric contraction.

    abstract::Changes in norepinephrine following a bimanual handgrip contraction test were used to evaluate the contribution of static physical effort exerted by the parturient on the rise in adrenergic stimulation observed during ongoing labor. Noradrenaline baseline values were 306.71 +/- (SE) 21.5 pg/ml); and after a maximal ef...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000298871

    authors: Rabinovici J,Rosenthal T,Peleg E,Mashiach S

    更新日期:1987-01-01 00:00:00

  • Changes of beta-1,4-galactosyltransferase with the development of endometrial cancer.

    abstract::To elucidate the mechanism of the type 2 carbohydrate chain accompanying the development of endometrial cancer, we studied the expression of beta-1,4-galactosyltransferase (beta-1,4GT) in normal endometrial and endometrial cancer tissues. An immunohistochemical study revealed that beta-1,4GT was diffusely positive in ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010158

    authors: Kubushiro K,Ma J,Fukuchi T,Banno K,Muramatsu Y,Tsukazaki K,Nozawa S

    更新日期:1999-01-01 00:00:00

  • The fate of trophoblast retained within the oviduct in the mouse.

    abstract::Pre-implantation blastocysts or trophoblast, obtained from ectoplacental cones, were transferred to the right oviducts of both pregnant and nonpregnant mice. Blastocysts which remained within the oviductal lumen did not show evidence of further differentiation into trophoblast although they readily implanted on variou...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299117

    authors: Tutton DA,Carr DH

    更新日期:1984-01-01 00:00:00

  • Lack of association of cytomegalovirus antibody level with carcinoma of the uterine cervix.

    abstract::Serum samples were collected from 199 patients attending a gynaecological clinic, colposcopy specimens being taken at the same time for routine pathology of paraffin sections which ranged from normal, through the degrees of dysplasia to carcinoma in situ. Other parameters noted were age, number of pregnancies and time...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299470

    authors: Hart H,Springbett A,Norval M

    更新日期:1982-01-01 00:00:00

  • Surgical treatment of urinary stress incontinence by a suburethral sling procedure using a Mersilene mesh graft.

    abstract::A suburethral sling procedure using a Mersilene mesh has been performed in 24 patients. Six patients had recurrent incontinence after an unsuccessful past operation. A postoperative follow-up was done for an average of 24 months. Twenty-three patients were free of symptoms, while only 1 patient had recurrent incontine...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292521

    authors: Guner H,Yildiz A,Erdem A,Erdem M,Tiftik Z,Yildirim M

    更新日期:1994-01-01 00:00:00

  • Placental alkaline phosphatase compared with human placental lactogen and oestriol in high-risk pregnancies.

    abstract::Serum levels of placental alkaline phosphatase (PLAP), human placental lactogen (HPL) and oestriol (E3) were investigated in 33 women with high-risk pregnancies. In pregnancies complicated by intrauterine growth retardation (IUGR) low PLAP values were constantly recorded. HPL values showed a similar pattern while E3 l...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299082

    authors: Ronin-Walknowska E,Holmgren PA,von Schoultz B,Stigbrand T

    更新日期:1984-01-01 00:00:00

  • The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats.

    abstract:OBJECTIVE:Isotretinoin is used in acne vulgaris treatment for more than 20 years. Isotretinoin has serious side effects on many organs, but there are no comprehensive studies investigating its possible toxic effects on reproductive organs. Thus, we aimed to investigate the possible toxic effects of isotretinoin adminis...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000510031

    authors: Kacamak P,Ozogul C,Saribas GS,Akarca Dizakar SO,Emniyet Sert AA

    更新日期:2020-01-01 00:00:00

  • Effects of add-back therapy on bone mineral density and pyridinium crosslinks in patients with endometriosis treated with gonadotropin-releasing hormone agonists.

    abstract::Treatment of endometriosis with gonadotropin-releasing hormone agonists (GnRHa) is limited to 6 months because of possible adverse effects on bone metabolism. We designed a randomized, double-blind, placebo-controlled, prospective study of 27 patients with endometriosis who were given GnRHa with or without hormone add...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000010059

    authors: Gnoth CH,Gödtke K,Freundl G,Godehardt E,Kienle E

    更新日期:1999-01-01 00:00:00

  • Ovarian fibrothecoma: sonographic and histologic findings.

    abstract::The sonographic and histologic findings observed in 11 cases of ovarian fibrothecoma were compared, and an attempt was made to find a correlation between each histologic type of the tumor (pure thecoma, predominantly fibrous fibrothecoma, mixed fibrothecoma) and its sonographic appearance. The presence of a homogeneou...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292992

    authors: Conte M,Guariglia L,Benedetti Panici P,Scambia G,Rabitti C,Capelli A,Mancuso S

    更新日期:1991-01-01 00:00:00

  • European Nationality Influence in the Management of Squamous Cell Vulvar Cancer.

    abstract:AIMS:Vulvar cancer is a rare disease. In western European countries, the incidence is 1.2 cases per 100,000 women/year. The aim of this study was to analyze the management and disease-free survival (DFS) of vulvar cancer among European countries. METHODS:An international multicenter retrospective study including patie...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000452097

    authors: Iacoponi S,Zapardiel I,VULCAN Study Collaborative Group.

    更新日期:2017-01-01 00:00:00

  • Construction and clinical significance of normal uterine arterial vascular network models.

    abstract:AIMS:To construct in vitro models of normal uterine arterial vascular network through vascular corrosion casting and explore their characteristics and clinical significances. METHODS:Three sets of uterus, vagina and bilateral adnexa were perfused and cast via uterine artery and ovarian artery, using 25, 20 and 15% chl...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000245941

    authors: Chen C,Huang R,Liu P,Ouyang Z,Guo H,Tang L,Li Z,Liu C,Wu K,Zhong G,Hong H,Hu J,Li J,Zhong S

    更新日期:2010-01-01 00:00:00

  • Insulin-like growth factor 1 receptor mRNA expression and autophosphorylation in human myometrium and leiomyoma.

    abstract::Uterine leiomyomas are the most common tumors of the genital tract. Growth factors seem to be implicated in the development of leiomyoma. The aim of this study was to determine insulin-like growth factor 1 receptor (IGF-1-R) mRNA levels and IGF-1-R tyrosine kinase activity in normal myometrium and leiomyoma. Plasma me...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000076690

    authors: Martin Chaves EB,Brum IS,Stoll J,Capp E,Corleta Hv

    更新日期:2004-01-01 00:00:00

  • Medical termination of pregnancy in acute intermittent porphyria.

    abstract::Acute intermittent porphyria is a rare autosomal dominant disease characterized by acute attacks of neuropsychiatric and neurovisceral dysfunction. In pregnancy, exacerbation of attacks in the form of seizures and acute abdomen occur due to hormonal changes. We report the case of a young woman presenting at 8 weeks of...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000091835

    authors: Sahu MT,Rajaram S,Saxena AK,Goel N,Ghumman S

    更新日期:2006-01-01 00:00:00

  • MIB 1 immunostaining in cervical intraepithelial neoplasia: prognostic significance in mild and moderate lesions.

    abstract:OBJECTIVE:MIB 1 is a new monoclonal antibody which recognizes nuclei of proliferating cells throughout the cell cycle except during the G0 and early G1 phases. In the present study we analyzed the MIB 1 immunostaining as an index of cellular proliferation in cervical intraepithelial neoplasia (CIN) and microinvasive ca...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000291977

    authors: Garzetti GG,Ciavattini A,De Nictolis M,Lucarini G,Goteri G,Romanini C,Biagini G

    更新日期:1996-01-01 00:00:00

  • Laparoscopic conservation of the ovaries in cases with massive ovarian oedema.

    abstract::Two women, one 27 years old (case 1) and the other 20 years old (case 2), were evaluated due to right lower quadrant pain. The lactate dehydrogenase level was increased in case 1 and the dihydroepiandostrone level was increased in both cases. Preoperative transvaginal ultrasonography revealed solid masses, but the tum...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000053009

    authors: Kocak M,Caliskan E,Haberal A

    更新日期:2002-01-01 00:00:00

  • Magnetic resonance spectroscopy features of uterine leiomyomas.

    abstract:OBJECTIVE:The purpose of this study is to investigate the in vivo magnetic resonance spectroscopy features of uterine leiomyomas using long echo time and to characterize the spectral patterns of these lesions. METHODS:We calculated metabolites in 15 patients with uterine leiomyomas and myometrium of 20 healthy control...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000080020

    authors: Celik O,Sarac K,Hascalik S,Alkan A,Mizrak B,Yologlu S

    更新日期:2004-01-01 00:00:00

  • Transvaginal ultrasonography of the endometrium in postmenopausal Japanese women.

    abstract:AIMS:To determine the cut-off level of endometrial thickness for detecting endometrial disease on a large scale of screening and to examine the usefulness of transvaginal ultrasonography (TVS) for endometrial disease screening in asymptomatic postmenopausal Japanese women. METHODS:The study involved 1,400 postmenopaus...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000087375

    authors: Tsuda H,Nakamura H,Inoue T,Kawamura N,Adachi K,Bandera CA

    更新日期:2005-01-01 00:00:00

  • Anaerobic vaginosis: treatment with tinidazole vaginal tablets.

    abstract::A prospective randomized trial comprising 90 patients was undertaken to evaluate three different regimens of tinidazole in the treatment of anaerobic vaginosis. Each group consisted of 30 women. The three regimens were: (A) oral tinidazole (150 mg X 2) for 7 days, (B) same oral treatment as above but also the partner ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000293524

    authors: Heikkinen J,Vuopala S

    更新日期:1989-01-01 00:00:00

  • Cesarean section in premature delivery.

    abstract::Cesarean sections were performed in 24 cases before the end of the 32nd week of pregnancy. Despite the fact that the indications for the operations were severe obstetric complications, the perinatal mortality was 25%, which should be compared to 23% for all children born in Sweden at that age., 2 of the surviving chil...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299827

    authors: Berg T,Lindberg BS

    更新日期:1980-01-01 00:00:00

  • Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro.

    abstract:BACKGROUND:Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on the release of progesterone by trophoblast cells in vitro. METHODS...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000080073

    authors: Jeschke U,Mylonas I,Richter DU,Streu A,Müller H,Briese V,Friese K

    更新日期:2004-01-01 00:00:00

  • Partial hydatidiform mole in the fallopian tube.

    abstract::An extremely rare case of partial hydatidiform mole located in the right Fallopian tube was diagnosed by ultrasonography and computed tomography. The lesion was excised, and the human chorionic gonadotropin (HCG) level in early morning urine fell below 1,000 IU/ml on postoperative day 11, and the serum HCG-beta level ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292708

    authors: Terada S,Suzuki N,Uchide K,Akasofu K

    更新日期:1993-01-01 00:00:00

  • Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780.

    abstract:BACKGROUND:All current major medications in treating endometriosis are effective in treating pain, most likely through suppression of proliferation of the implants, yet their effectiveness is relatively short term and they all have many undesirable, and sometimes severe, side effects. There is pressing need for novel, ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000093975

    authors: Wu Y,Guo SW

    更新日期:2006-01-01 00:00:00

  • Vaginal ultrasonographic and hysterosonographic evaluation of the low transverse incision after caesarean section: correlation with gynaecological symptoms.

    abstract:AIM:We investigated whether there is a correlation between morphological changes of the lower uterine segment after caesarean section (CS), visualized by means of either a transvaginal sonography (TVS) or a sonohysterography (SHG), and the frequency of abnormal uterine bleedings reported by the women. METHODS:By means...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000091497

    authors: Menada Valenzano M,Lijoi D,Mistrangelo E,Costantini S,Ragni N

    更新日期:2006-01-01 00:00:00