Clinical significance of squamous cell carcinoma antigen in cancer of the human uterine cervix. Comparison with CEA and CA-125.

Abstract:

:Serum squamous cell carcinoma antigen (SCCa) concentrations were determined by a radioimmunoassay kit before and during the treatment of 50 patients with cervical carcinoma: 44 with squamous cell carcinoma (SCC) and 6 with adenocarcinoma. The positivity rate of SCCa was 50% (52% for SCC and 33% for adenocarcinoma). The sensitivity of SCCa for SCC was twice as high as that of CEA and CA-125. Low serum concentrations were observed in early-stage carcinoma, indicating that SCCa is not useful for diagnosis. In advanced cases, serum levels were directly and significantly correlated with the stage of the disease.

journal_name

Gynecol Obstet Invest

authors

Verlooy H,Devos P,Janssens J,Mortelmans L,Gerits M,Bonte J,De Roo M

doi

10.1159/000292993

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

55-8

issue

1

eissn

0378-7346

issn

1423-002X

journal_volume

32

pub_type

杂志文章
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    pub_type: 杂志文章

    doi:10.1159/000292732

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