Abstract:
:Serum squamous cell carcinoma antigen (SCCa) concentrations were determined by a radioimmunoassay kit before and during the treatment of 50 patients with cervical carcinoma: 44 with squamous cell carcinoma (SCC) and 6 with adenocarcinoma. The positivity rate of SCCa was 50% (52% for SCC and 33% for adenocarcinoma). The sensitivity of SCCa for SCC was twice as high as that of CEA and CA-125. Low serum concentrations were observed in early-stage carcinoma, indicating that SCCa is not useful for diagnosis. In advanced cases, serum levels were directly and significantly correlated with the stage of the disease.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Verlooy H,Devos P,Janssens J,Mortelmans L,Gerits M,Bonte J,De Roo Mdoi
10.1159/000292993subject
Has Abstractpub_date
1991-01-01 00:00:00pages
55-8issue
1eissn
0378-7346issn
1423-002Xjournal_volume
32pub_type
杂志文章abstract::Fifty-six patients with pelvic endometriosis were treated with a buserelin dosage of 200 micrograms/day s.c. for 6 months. Scoring of the American Fertility Society (AFS) for endometriosis was performed by laparoscopy in all cases before and at the end of therapy. Serum CA-125 and estradiol levels were determined befo...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292491
更新日期:1994-01-01 00:00:00
abstract::Hysteroscopic surgery is widely used for the treatment of patients suffering from menorrhagia. In different studies, pretreatment of the endometrium with GnRH analogues (GnRH-a) prior to endometrial ablation has been reported to increase the success rate, as well as to reduce the menstrual blood flow, accounting for a...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000052847
更新日期:1998-01-01 00:00:00
abstract::A defect in placental function has been suggested to be associated both with preeclampsia (PE), with or without concomitant intrauterine growth retardation (IUGR), and with IUGR as a single entity. Our aim was to compare the mRNA expression of the growth-related protooncogenes c-fos and c-jun and the vasoconstrictor a...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291494
更新日期:1997-01-01 00:00:00
abstract::The concentration of collagen in the human uterine cervix decreases during pregnancy. This change contributes to the ripening process, which facilitates cervical dilatation during labor. It has been suggested that cervical collagen is partly degraded at term and after delivery. In order to evaluate this hypothesis we ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298975
更新日期:1985-01-01 00:00:00
abstract::E3 and HPL hormone levels in maternal plasma are predictable of adequate birth weight for gestation age (AGA) when their values are higher than the mean for the term of pregnancy, but low values correspond to 'small-for-gestation-age' (SGA) infants in about 50% of the cases only. DHA-S (50 mg i.v.) half-life (DHS-S t ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299834
更新日期:1980-01-01 00:00:00
abstract::The study's objective was to determine if using human chorionic gonadotropin (hCG) as a timing method for intrauterine insemination (IUI) in patients who make mature follicles but have cervical factor problems has a negative effect on pregnancy rates (PRs) (possibly by releasing an immature oocyte), or increases the r...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000292447
更新日期:1994-01-01 00:00:00
abstract:AIMS:To determine the cut-off level of endometrial thickness for detecting endometrial disease on a large scale of screening and to examine the usefulness of transvaginal ultrasonography (TVS) for endometrial disease screening in asymptomatic postmenopausal Japanese women. METHODS:The study involved 1,400 postmenopaus...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000087375
更新日期:2005-01-01 00:00:00
abstract::Using a 4-MHz continuous-wave Doppler device, standard rates were established for resistance index (RI) and pulsatility index (PI) of uterine and arcuate arteries of 612 patients with uneventful pregnancies and deliveries. From 18 to 41 weeks of gestation, neither RI nor PI of uterine or arcuate arteries proved to var...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292732
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND/AIMS:Adenomyosis is a common condition with a poorly understood pathogenesis. Recent data suggest that it may be an epigenetic disease. This study investigated the expression and localization of class I histone deacetylases (HDACs) in women with and without adenomyosis. METHODS:The ectopic and homologous eu...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000336409
更新日期:2012-01-01 00:00:00
abstract::This study was undertaken to evaluate the response to parenteral administration of iron in 62 pregnant patients with asiderotic anemia and mean initial hemoglobin (Hb) concentrations (Hb1) of 9.91+/-(SD) 1.13 g/dl. Iron (742+/-366 mg) was administered intravenously, and the response to treatment was classified accordi...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000010109
更新日期:1999-01-01 00:00:00
abstract::To elucidate the mechanism of the type 2 carbohydrate chain accompanying the development of endometrial cancer, we studied the expression of beta-1,4-galactosyltransferase (beta-1,4GT) in normal endometrial and endometrial cancer tissues. An immunohistochemical study revealed that beta-1,4GT was diffusely positive in ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010158
更新日期:1999-01-01 00:00:00
abstract::The concentration of P29, a phosphoprotein related to estradiol receptor (RE), was measured by an immunoradiometric assay in human breast cancer cytosol and the results compared with the levels of RE and progesterone receptors (RP), as measured by the classical ligand-binding assay. Good linear correlation was found b...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293689
更新日期:1988-01-01 00:00:00
abstract::A solitary peritoneal metastasis from a poorly differentiated adenocarcinoma of unknown origin in a 38-year-old female is described. The patient presented with a left ovarian tumor and elevated cancer antigen 125. She underwent complete excision of tumor and received six courses of postoperatively adjuvant cisplatin-b...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291858
更新日期:1997-01-01 00:00:00
abstract::Monochorionic triplet pregnancies are very rare. Here we report 2 cases of multiple pregnancies with monochorionic triplets following intracytoplasmic sperm injection (ICSI) and day 3 embryo transfer. The 2 women concomitantly underwent controlled ovarian hyperstimulation due to male factor infertility. Following oocy...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000076786
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND/AIMS:A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) enzymes take part in extracellular matrix (ECM) remodeling which has been shown to contribute to the ovulation and follicular functions. We aimed to compare serum levels of ADAMTS-19 in patients with different fertility situations. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000490665
更新日期:2019-01-01 00:00:00
abstract:AIM:To determine factors associated with intrapartum fever and to examine associated maternal and neonatal outcomes. METHODS:Retrospective study of patients between 360/7 and 420/7 gestational weeks who entered spontaneous or induced active labor and developed temperature ≥38°C; a similar group that did not develop fe...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000453611
更新日期:2017-01-01 00:00:00
abstract::We report a postmenopausal patient with serous papillary cystadenocarcinoma of the ovary associated with large abscess formation and estrogen production. Ovarian cancer accompanied by stromal function is an occasional event, but large abscess association is a rarity. The present case is thus even rarer. Her clinical c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292710
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To investigate the expression of T-cell immunoglobulin and mucin domain 3 (TIM-3) on peripheral T cells of cervical carcinoma patients. METHODS:Peripheral blood samples from 15 high-grade cervical squamous intraepithelial lesion (HSIL) patients, 24 cervical carcinoma patients, and 21 healthy controls were co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000511440
更新日期:2020-12-04 00:00:00
abstract:BACKGROUND/AIMS:Low molecular weight heparin is recommended for the treatment of venous thromboembolism (VTE) during pregnancy. However, there are few reliable data regarding the safety of therapeutic doses of tinzaparin in this setting. The objective of this study was to assess the safety of once-daily therapeutic dos...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000367846
更新日期:2015-01-01 00:00:00
abstract::We propose a new scoring system for intrauterine adhesions (IUA) that may predict the prognosis after hysteroscopic adhesiolysis. We analyzed hysteroscopic findings and clinical data of patients diagnosed as having IUA by reviewing previously published hysteroscopic classifications of IUA. The data were subjected to e...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010305
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND/AIMS:Adiponectin receptor 1 (ADIPOR1) is an identified receptor for adiponectin, an adipocytokine with anti-inflammatory and insulin-sensitizing properties. The ADIPOR1 gene is a potential candidate gene in polycystic ovary syndrome (PCOS). The aim of this study is to assess the association between single-nu...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000356960
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Single-port laparoscopy (LESS) utilizes a single, multichannel port in an attempt to decrease postoperative pain, while enhancing cosmesis and minimizing the potential risks and morbidities associated with the multiple ports used in conventional laparoscopy. METHODS:We performed a retrospective study examin...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000367659
更新日期:2015-01-01 00:00:00
abstract::Tubal occlusion using Filshie clip is one of the most commonly performed operations for female sterilization. It is usually a simple and safe procedure, and operative complications are uncommon. We report a rare case of spontaneous expulsion of a Filshie clip through the anterior abdominal wall 5 years after steriliza...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000070615
更新日期:2003-01-01 00:00:00
abstract::Omental pregnancy is a rare form of abdominal pregnancy. In the 5 previously reported cases, primary implantation of the embryo to the omentum has been proposed as its etiology. We present a new case of omental pregnancy in a 31-year-old woman presenting with symptoms of ectopic pregnancy. After careful review of our ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000291922
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was determination and comparative analysis of the maternal and umbilical cord sCD40L serum levels in pregnancies complicated by pre-eclampsia with and without intrauterine growth retardation (IUGR) and in normotensive pregnancies. PATIENTS AND METHODS:The study was carried out on 16 pat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000098316
更新日期:2007-01-01 00:00:00
abstract::The function of adrenoceptors in the female genital tract was tested estimating the uptake of 3H-noradrenaline (3H-NA) in vitro in oviductal, uterine arterial and myometrial tissue samples obtained from 74 women. The highest 3H-NA value, 64 +/- 5 ng/g, was in the oviduct (p less than 0.001 vs. uterine artery and myome...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293673
更新日期:1988-01-01 00:00:00
abstract::A dietary approach has proven to be effective in alleviating symptoms of premenstrual syndrome. In our previous studies, magnesium improved premenstrual irritability and mood scoings. In this double-blind, placebo-controlled study, we evaluated the effects of a new dietetic preparation (Sillix Donna, Giuliani) in 40 p...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000291836
更新日期:1997-01-01 00:00:00
abstract::We present the case of a female fetus aborted in the 20th week of gestation due to severely dysplastic kidneys, anhydramnios and hydranencephalus. The combination of these malformations is extremely rare, resulting in only 4 cases described so far. Our case is the first ever presented in a female showing polycystic-dy...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000291522
更新日期:1997-01-01 00:00:00
abstract::Semistructured interviews were made among a random sample of applicants for abortion in Stockholm, when legal abortion on demand had been available in Sweden for 10 years. One hundred and twenty women were interviewed, 75 of them having their first abortion and 45 having a repeat abortion. The use of contraceptives wa...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292572
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:In this study, we aimed to compare the levels of maternal blood lipids, placental and venous blood lipid transporters, and inflammatory factor receptors in pregnant women with and without gestational diabetes mellitus (GDM). We also aimed to figure out the relationship between these values and neonatal weigh...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000510032
更新日期:2021-01-22 00:00:00