Altered growth hormone secretion during oral contraception.

Abstract:

:Serum profiles of growth hormone (GH) were recorded for 24 h in 9 young healthy women before and during treatment with monophasic, combined contraceptives. During treatment, there was a change in GH secretion towards a pattern of smaller peaks at a higher frequency. The mean peak amplitude decreased from 11.2 to 7.3 mU/l, the mean peak area from 24.1 to 14.1 mU/l, and the mean interpeak interval from 4.3 to 3.0 h. The biological impact of altered GH secretion is well-known from animal experiments. A sex-steroid-induced change in GH secretion may be relevant for certain metabolic effects of oral contraceptives.

journal_name

Gynecol Obstet Invest

authors

Karlsson R,Edén S,von Schoultz B

doi

10.1159/000293276

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

234-8

issue

4

eissn

0378-7346

issn

1423-002X

journal_volume

30

pub_type

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