Abstract:
AIMS:To investigate the differences in insulin resistance between women with recurrent miscarriage and those with normal pregnancy. METHODS:Pregnant women with a history of recurrent miscarriage were included in the patient group (n = 97), while those with no history of abnormal pregnancy were included in the control group (n = 52). Both groups consented to undertake an oral glucose tolerance test and insulin-releasing test between the 5th and 13th weeks of pregnancy. RESULTS:(1) Levels of fasting plasma glucose, fasting plasma insulin, homeostasis model assessment of insulin resistance index, and homeostasis model assessment β function were not statistically significantly different (p < 0.05) between the two groups. (2) The area under the curve of glucose and area under the curve of insulin were higher in the patient group than in the control group. The composite insulin sensitivity index of the patient group was lower than that of the control group. The differences in these three parameters between the groups were statistically significant (p < 0.05). CONCLUSION:Women with a history of recurrent miscarriage are at an increased risk for insulin resistance during the first trimester of a new pregnancy.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Wang Y,Zhao H,Li Y,Zhang J,Tan J,Liu Ydoi
10.1159/000325165subject
Has Abstractpub_date
2011-01-01 00:00:00pages
245-51issue
4eissn
0378-7346issn
1423-002Xpii
000325165journal_volume
72pub_type
杂志文章abstract::The feasibility of performing hysteroscopic endomyometrial resection using isotonic 2.2% glycine as distension medium was studied in 181 consecutive operations. A standard continuous flow loop-resectoscope was used. Distension was achieved by means of a gravity-fed system and glycine flowed out under its own pressure....
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010119
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:The endometriosis fertility index (EFI) is a novel index for predicting pregnancy after surgery. We investigated the utility of the EFI for predicting the ability to conceive without assisted reproductive technology (ART) treatment after laparoscopic surgery. METHODS:From July 2011 through December 2012, we ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000480454
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Angioleiomyoma (ALM) is a rare, benign neoplasm involving the peripheral soft tissues. ALM has not previously been described to originate from the ovary. We present a case herein of a premenarchal girl with a large ALM originating from the ovary. CASE:An 11-year-old girl underwent a laparotomy during the co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000113083
更新日期:2008-01-01 00:00:00
abstract::Previous reports have supported an association between tobacco smoking and cervical neoplasia. Our observations show an association between smoking and a reduction of the numerical densities of Langerhans cells and of helper/inducer T lymphocytes in the squamous epithelia of the transformation zone of the uterine cerv...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292372
更新日期:1995-01-01 00:00:00
abstract::Monochorionic triplet pregnancies are very rare. Here we report 2 cases of multiple pregnancies with monochorionic triplets following intracytoplasmic sperm injection (ICSI) and day 3 embryo transfer. The 2 women concomitantly underwent controlled ovarian hyperstimulation due to male factor infertility. Following oocy...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000076786
更新日期:2004-01-01 00:00:00
abstract::Placental hemosiderin deposition representing intrauterine bleeding at least 24-48 h before delivery is detected frequently in prematurity. The objective of this study was to assess incidence and site of histologic evidence of intrauterine bleeding in association with fetal growth in prematurity. Placentas of consecut...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010289
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND/AIMS:To determine whether genetic alterations in the CD9 gene are associated with female infertility in humans. METHODS:We sequenced the entire coding region of this gene in 86 Japanese women with unexplained infertility and further conducted a case-control study of six tagging single nucleotide polymorphis...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000262451
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Dyslipidemia is commonly observed in polycystic ovary syndrome (PCOS) patients. Bezafibrate is a drug for dyslipidemia acting through peroxisome proliferator-activated receptors. We investigated the effects of bezafibrate for ovulation induction in patients with PCOS with dyslipidemia who were resistant to c...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000316265
更新日期:2010-01-01 00:00:00
abstract::Adenocarcinoma of the endometrium with intrauterine pregnancy is extremely rare. We report the case of a 35-year-old woman with endometrial cancer discovered in the 7th gestational week. A therapeutic abortion was performed and because of bleeding and spotting dilatation and curettage was done 10 days later. Histology...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292043
更新日期:1996-01-01 00:00:00
abstract::Uterine myoma leading to uremia in young women below 16 years of age is an extremely rare condition. On reviewing the literature we have not been able to find any case similar to the one described below. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293043
更新日期:1991-01-01 00:00:00
abstract::To test the effects of calcium dobesilate (Doxium) in pregnancies complicated with pregnancy-induced hypertension or mild/moderate pre-eclampsia a double-blind, placebo-controlled pilot study was carried out. Primigravida patients (gestational age =34 weeks) daily took 2 g Doxium or placebo until delivery. Twelve pa...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000010080
更新日期:1999-01-01 00:00:00
abstract::Alternations of the pelvic structure with an emphasis on those of the levator ani muscle, associated with uterine prolapse, were studied using sagittal magnetic resonance images obtained from 19 subjects without and 14 with uterine or vaginal prolapse of varied degree and 3 patients with Rokitansky syndrome who had un...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292723
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:MIB 1 is a new monoclonal antibody which recognizes nuclei of proliferating cells throughout the cell cycle except during the G0 and early G1 phases. In the present study we analyzed the MIB 1 immunostaining as an index of cellular proliferation in cervical intraepithelial neoplasia (CIN) and microinvasive ca...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291977
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Little is known about proper interval periods between the flushings of totally implantable access ports after completion of chemotherapy. Manufacturer guidelines recommend flushing catheters every 4 weeks. METHODS:This retrospective study examined whether flushing less than every 4 weeks conferred any benef...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294919
更新日期:2010-01-01 00:00:00
abstract::Two women, one 27 years old (case 1) and the other 20 years old (case 2), were evaluated due to right lower quadrant pain. The lactate dehydrogenase level was increased in case 1 and the dihydroepiandostrone level was increased in both cases. Preoperative transvaginal ultrasonography revealed solid masses, but the tum...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000053009
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Cisplatin is used as a key drug for ovarian yolk sac tumor (YST), but relapse may occur. Details of the molecular mechanism responsible for cisplatin resistance remain unclear. METHODS:We established cisplatin-resistant ovarian YST cells (NOY1-CR) from parent NOY1. To characterize these cells, we examined c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000320744
更新日期:2011-01-01 00:00:00
abstract::The objective of the present study was to compare the rate of embryo cleavage after oocyte insemination with capacitated spermatozoa in the presence or absence of follicular fluid. In the first experiment, a total of 67 oocytes were inseminated with spermatozoa which had been submitted to part of the capacitation proc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292545
更新日期:1994-01-01 00:00:00
abstract::In a prospective study the cyclic changes in the cervical microflora and the endometrial histology were correlated with the incidence of postoperative infections in 99 women undergoing elective abdominal hysterectomy. Escherichia coli and Bacteroides fragilis were isolated more frequently during the proliferative phas...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299447
更新日期:1982-01-01 00:00:00
abstract:AIM:To compare outcomes after laparoscopic ovarian cystectomy versus fenestration/coagulation or laser ablation for the treatment of endometriomas. METHODS:Studies were identified by searching the PubMed, EMBASE, SCOPUS, and Cochrane Central Register of Controlled Trials databases using the terms ovarian, endometrioma...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,meta分析
doi:10.1159/000351165
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:The purpose of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in sclerostin (SOST), dickkopf (DKK), secreted frizzled-related protein (sFRP) genes and bone mineral density (BMD) in postmenopausal Korean women. METHODS:The SOST, Wnt inhibitory factor 1 (WIF1...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000358389
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To determine the effects of the nitric oxide (NO) precursor L-arginine on the airway NO concentration in patients with preeclampsia. METHODS:NO was measured by a noninvasive chemiluminescence technique in air sampled directly from nasal and oral cavities during expiration before and during L-arginine infusio...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010040
更新日期:1998-01-01 00:00:00
abstract:AIMS:The study aimed to assess the diagnostic value of serial monitoring of biochemical inflammatory markers (C-reactive protein (CRP) and white blood cell (WBC) count) in the postoperative diagnosis of anastomotic leakage or ureteral injury after bowel resection for deep infiltrating endometriosis. METHODS:This is a ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000447513
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Epithelial ovarian carcinoma produces steroid hormones that may be of prognostic importance. The steroids are mainly bound to plasma albumin and sex hormone-binding globulin. Alterations in plasma protein levels influence hormonal effects. As plasma prealbumin may reflect changes in the patient's clinical st...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292542
更新日期:1994-01-01 00:00:00
abstract::We herein present a case of exencephaly with rachischisis, situs ambiguous and club feet, diagnosed antenatally by ultrasound. This combination of anomalies is very rare. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293305
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Tuberculous paraplegia as a consequence of spinal infiltration in pregnancy is reported to be rare. Analysis of the current literature produces few case studies that report successful outcomes. Delay in diagnosis and treatment may ultimately result in an irreversible neurological deficit. The potential impli...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000235869
更新日期:2009-01-01 00:00:00
abstract::The objective of the study was to assess the effects of low-dose vaginal treatment with oestradiol before vaginal operation. In a double-blind randomized study including 43 postmenopausal women scheduled for vaginal repair operation for genital descensus, it was found that 7 patients suffered from concomitant urinary ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000292320
更新日期:1995-01-01 00:00:00
abstract::The adherence of Neisseria gonorrhoeae, Escherichia coli and group B streptococci to vaginal epithelial cells from post-menopausal women was studied by an in vitro test system. It was found that the adherence rate of gonococci to vaginal cells from women on oestrogen treatment was statistically significantly higher (p...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299855
更新日期:1980-01-01 00:00:00
abstract::Highly evacuated (980 mbar) wound drainage systems according to Redon were used in 100 gynecologic laparotomies. In 96% of cases, no flask exchange was required before the system was removed. Bacteriological specimens from various locations of the Redon system showed minimal colonization with pathogenic bacteria. No c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293758
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Genetic factors may play a role in male infertility. METHODS:In a prospective case-control study, we assessed the allele and genotype frequencies of the TNFalpha -308 C-->T and -863 C-->A polymorphisms, detected by PCR of sperm DNA, of 577 Caucasian men recruited in an infertility clinic. Semen sampling was...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000126494
更新日期:2008-01-01 00:00:00
abstract::Receptor sites for 7 FITC-conjugated lectins were examined on preimplantation mouse embryos at various stages of development: zygotes; 2; 6-8 cells; morulae; blastocyst; expanded blastocyst, and isolated inner cell mass. In order to determine the solidity of the binding, the embryos were incubated with lectins, washed...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298787
更新日期:1987-01-01 00:00:00