Abstract:
:Previous reports have supported an association between tobacco smoking and cervical neoplasia. Our observations show an association between smoking and a reduction of the numerical densities of Langerhans cells and of helper/inducer T lymphocytes in the squamous epithelia of the transformation zone of the uterine cervix. This suggests a local impairment of cell-mediated immunity by smoking. This immunosuppressive effect could support the concept that smoking is an independent risk factor for cervical neoplasia.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Poppe WA,Ide PS,Drijkoningen MP,Lauweryns JM,Van Assche FAdoi
10.1159/000292372subject
Has Abstractpub_date
1995-01-01 00:00:00pages
34-8issue
1eissn
0378-7346issn
1423-002Xjournal_volume
39pub_type
杂志文章abstract:AIM:The aim of this study was to evaluate whether natural fertility is related to serum 25-hydroxyvitamin D (25-OH-vitamin D) levels. METHODS:A nested case-control study was designed from a prospective cohort of pregnant women undergoing first trimester screening for aneuploidies. Cases included women seeking pregnanc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000443397
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Preeclampsia (PE) is associated with oxidative stress in the maternal circulation and placenta. This study aimed to determine if inhibition of lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gives protection against oxidative stress-mediated trophoblast dysfunction. METHODS:Plasma and placen...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000370195
更新日期:2015-01-01 00:00:00
abstract::There is no current consensus on the best treatment modality for cesarean scar pregnancy (CSP) with favorable reproductive and pregnancy outcome. We treated 3 cases of symptomatic CSP with fetal cardiac activity. The first case underwent laparoscopic repair at 6 weeks' gestational age of unruptured CSP. The second pat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000364867
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of depot medroxy progesterone acetate (DMPA) as a preparatory agent for endometrial resection. STUDY DESIGN:Endometrial resection was performed on 50 women for excessive uterine bleeding. The patients were randomly divided into 2 equal groups, with the first group receiving DMPA and ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000052969
更新日期:2001-01-01 00:00:00
abstract::One-sided artificial hydrosalpinx was caused in mature New Zealand rabbits by proximal and distal ligature. After 2 weeks the average secretion accumulation was 2.1 ml, after 8 weeks 6.3 ml. A fold relief could no longer be detected after 8 weeks. The light-microscopical study of the epithelium showed signs of cell de...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299469
更新日期:1982-01-01 00:00:00
abstract::A search of the literature has been prepared to determine how oxytocin may affect sexual and reproductive in women. Many animal studies suggest that oxytocin induces a variety of reproductive behaviors, including grooming, sexual arousal, orgasm, gamete transport, nesting, birthing, and specific maternal behaviors suc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000292340
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND/AIMS:Previous studies on the effects of estrogen on sclerostin regulation were conducted in postmenopausal women in humans or animals following estrogen treatment or induced estrogen deficiency. The aim of this study was to evaluate the effects of sex hormones on serum sclerostin levels in premenopausal wome...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000347013
更新日期:2013-01-01 00:00:00
abstract::Estrogen (ER) - and progestagen (PgR) - receptors were estimated by a DCC method using Scatchard plot analysis In tissue samples of 68 patients with ovarian carcinomas. The mean ER and PgR levels were at 52 and 74 fmol/mg cytosol protein, respectively. ER+ PgR+ records were noted in 32.4%, ER+ PgR- in 26.4%, ER- PgR+ ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299256
更新日期:1983-01-01 00:00:00
abstract:AIMS:The study aimed to assess the efficacy of accelerating the process of coasting through adding gonadotropin releasing hormone (GnRH) antagonist (GnRH-ant) on the day of triggering of oocyte maturation without withholding the GnRH agonist (GnRHa) in women at risk for developing ovarian hyperstimulation syndrome (OHS...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000477297
更新日期:2018-01-01 00:00:00
abstract::To determine the placental clearance of lactate and bicarbonate in sheep, the fetal side of an isolated cotyledon and the umbilical circulation of the total placenta were artificially perfused. The release and uptake of lactate and bicarbonate by the perfusion fluid and the fetomaternal concentration differences of th...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299913
更新日期:1979-01-01 00:00:00
abstract::Breast involvement in ovarian cancer is extremely rare. We report a case of solitary breast metastasis from ovarian carcinoma in a 43-year-old white woman, 3 months following diagnosis of ovarian cancer. The diagnostic, therapeutic and prognostic aspects as well as a review of the literature of this uncommon site of m...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052946
更新日期:2001-01-01 00:00:00
abstract::The aim of the present study was to investigate whether women with endometriosis displayed a decreased lymphokine-activated killer (LAK) activity. In 15 women with and 7 women without endometriosis the cytotoxicity against four different tumor cell lines--K562, the endometrium carcinomas AN3CA and RL95, the natural-ki...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292556
更新日期:1994-01-01 00:00:00
abstract:AIM:To compare outcomes after laparoscopic ovarian cystectomy versus fenestration/coagulation or laser ablation for the treatment of endometriomas. METHODS:Studies were identified by searching the PubMed, EMBASE, SCOPUS, and Cochrane Central Register of Controlled Trials databases using the terms ovarian, endometrioma...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,meta分析
doi:10.1159/000351165
更新日期:2013-01-01 00:00:00
abstract::The study describes Kock's continent ileostomy in 2 females, both of whom were suffering from tubal infertility. Appropriate placement of the abdominal pouch, permitting in vitro fertilization embryo transfer treatment, was present in 1 patient. In the other patient, an ultrasonographic examination demonstrated the po...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293324
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:Premature labor is still the leading cause of infant mortality and morbidity worldwide. Multiple etiological factors including genetics and environment are held responsible for preterm birth. However, scientific data regarding the link between premature birth and genetics are limited. SUBJECTS AND METHODS:In...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000237743
更新日期:2009-01-01 00:00:00
abstract::We present a case of leiomyomatosis peritonealis disseminata (LPD) after myoma morcellation and review the literature using the keywords leiomyomatosis peritonealis disseminata and disseminated peritoneal leiomyomatosis. The search was conducted in Medline, EMBASE, and Cochrane Database of systematic reviews. We encou...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000274487
更新日期:2010-01-01 00:00:00
abstract::In 15 normal mothers the stress effects of labor on zinc and copper distributions in erythrocytes and plasma were investigated. Lower levels of total zinc and of zinc derived from both carbonic anhydrase isoenzymes (CA-I and CA-II), especially from CA-I, in erythrocytes were obtained immediately after delivery. On the...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298798
更新日期:1987-01-01 00:00:00
abstract::A prospective randomized trial comprising 90 patients was undertaken to evaluate three different regimens of tinidazole in the treatment of anaerobic vaginosis. Each group consisted of 30 women. The three regimens were: (A) oral tinidazole (150 mg X 2) for 7 days, (B) same oral treatment as above but also the partner ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000293524
更新日期:1989-01-01 00:00:00
abstract::Maternofetal transfer of ritodrine and its effect on placental glucose and oxygen consumption were studied using a recycling perfusion of maternal and fetal circulations of an isolated cotyledon of a term human placenta. 3H-labeled ritodrine was introduced into the maternal side of the perfusion system. Transfer was c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292983
更新日期:1991-01-01 00:00:00
abstract::We studied the effects of caffeine ingestion during pregnancy. A total number of 9,921 healthy pregnant women with a gestational age after 24 weeks were subjected to the study. The women who drank more than 5 cups of coffee per day had a high incidence of impending abortion, premature labor, and fetuses small for gest...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299032
更新日期:1985-01-01 00:00:00
abstract::The function of adrenoceptors in the female genital tract was tested estimating the uptake of 3H-noradrenaline (3H-NA) in vitro in oviductal, uterine arterial and myometrial tissue samples obtained from 74 women. The highest 3H-NA value, 64 +/- 5 ng/g, was in the oviduct (p less than 0.001 vs. uterine artery and myome...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293673
更新日期:1988-01-01 00:00:00
abstract::A small dermatan sulphate proteoglycan has been isolated from the human uterine cervix. The concentration of this proteoglycan has been shown to decrease during pregnancy. To study the mechanism behind this change fibroblasts from the human uterine cervix were established in culture. Their synthesis and secretion of p...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299026
更新日期:1985-01-01 00:00:00
abstract::This study deals with the effects of smoking on serum ceruloplasmin and its ferroxidase activity in pregnant women. The mean value (+/- SD) of serum ceruloplasmin in women smokers during pregnancy is significantly higher (p < 0.01) in comparison to that of nonsmokers, whereas the ferroxidase activity of ceruloplasmin ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291880
更新日期:1996-01-01 00:00:00
abstract::Pathologic material was reviewed and survival data were obtained on 182 of the endometrial cancer patients reported in our previous study (1975) to compare histopathologic characteristics and clinical behavior (survival) between endometrial adenocarcinoma in estrogen users and nonusers. In addition, relative risk esti...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299600
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:To determine whether a diminished intrapartum amniotic fluid volume represents a risk of adverse neonatal outcome when it occurs in conjunction with prolonged labor. METHODS:The intrapartum amniotic fluid index (iAFI) was measured in 242 parturients over 35 weeks of gestation during 1st-stage labor, and the ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000049402
更新日期:2002-01-01 00:00:00
abstract::A second pregnancy was successfully achieved by a menopausal women who had previously conceived and delivered an infant using donated oocytes. The same nonanonymous oocyte donor provided the gametes for both procedures. Prior to embryo transfer, the functionally agonadal recipient received exogenous steroid hormone re...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293009
更新日期:1991-01-01 00:00:00
abstract::An evaluation of the age distribution of erythrocytes in twin gestation was performed. Based on previous studies on age distribution of erythrocytes in late pregnancy, we have proposed that a more pronounced shift in age distribution of erythrocytes in twin pregnancy may be expected. We have used the density distribut...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292618
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Multiple malignancies of the urogenital tract have been reported. We investigated the etiological role of human papillomavirus (HPV) in the pathogenesis of urogenital cancers. CASE:We present a case of cervical squamous carcinoma in a 64-year-old woman who subsequently developed Bowen's disease in the peria...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000097139
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND/AIMS:The study aimed to evaluate molecular changes related to trophoblast adhesion in placenta accreta spectrum (PAS) disorders. METHODS:A retrospective analysis of 10 PAS cases in which both the trophoblast adherent site and the non-adherent site were identified was performed in April 2010 and March 2013. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000496609
更新日期:2019-01-01 00:00:00
abstract::Oviducts of 35 mature, white New Zealand rabbits were injured by a laser beam, using various powers from 25 to 40 W, and by a series of pulses of 1/10, 1/20 or 1/100 s duration. The contralateral oviducts served as controls and were injured at similar areas by a scalpel. The injured areas of both tubes were histologic...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299610
更新日期:1981-01-01 00:00:00