Abstract:
:We studied the effects of caffeine ingestion during pregnancy. A total number of 9,921 healthy pregnant women with a gestational age after 24 weeks were subjected to the study. The women who drank more than 5 cups of coffee per day had a high incidence of impending abortion, premature labor, and fetuses small for gestational age. The heavy coffee drinkers among the pregnant women had high rates of spontaneous abortion, chromosomal abnormality and congenital multi-anomalies. However, we would like to stress that the multiple socioeconomic variables might be more important than any direct effect of caffeine.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Furuhashi N,Sato S,Suzuki M,Hiruta M,Tanaka M,Takahashi Tdoi
10.1159/000299032subject
Has Abstractpub_date
1985-01-01 00:00:00pages
187-91issue
4eissn
0378-7346issn
1423-002Xjournal_volume
19pub_type
杂志文章abstract::The effect of the moon on the number of newborns has been investigated extensively with contradictory results but with few significant findings. In this paper, a possible lunar effect is analyzed by a nonlinear Poisson regression model similar to a Fourier analysis based on all children (n = 2,760,362) born in Austria...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052999
更新日期:2002-01-01 00:00:00
abstract::Acupuncture treatment in the final weeks of pregnancy has been claimed to shorten the duration of labor in primiparous women. In the present study, the length of the various phases of labor was calculated for 56 primiparous women who were repeatedly treated with manual acupuncture during the month prior to parturition...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298806
更新日期:1987-01-01 00:00:00
abstract::Minimal deviation adenocarcinoma (MDA) is a very rare variant of cervical adenocarcinoma, this pathological entity is composed of mucinous very-well-differentiated glands deeply invading cervical stroma, and often surrounded by a desmoplastic reaction. Despite its benign histological appearance, MDA is typically chara...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000327938
更新日期:2011-01-01 00:00:00
abstract::A case control study was performed to examine possible morbidity associated with Chlamydia trachomatis in 15 pregnant women with idiopathic preterm premature rupture of the membranes (PROM; group A), and in two control groups, 35 healthy preterm pregnant women (group B), and 43 healthy pregnant women at term (group C)...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000293249
更新日期:1990-01-01 00:00:00
abstract::The correlation between arousal state and fetal habituation was tested. Four behavioral states were determined according to fetal heart activity and movement pattern in 52 fetuses. Repeated wide low-frequency sound was used as external stimulus. Ceasing of response to 5 consecutive stimuli indicated habituation. The t...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293315
更新日期:1990-01-01 00:00:00
abstract::The present study was undertaken to investigate the opinions of health professionals working in family planning clinics in Italy and Sweden. The comparison of two such different countries seemed of interest both to describe differences and/or similarities between the samples as well as to analyze factors that could in...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293118
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:Limited information is available regarding the quantity of blood loss associated with uncomplicated transvaginal oocyte retrieval. The aim of the present study was evaluating the quantity of such a loss. METHODS:One hundred and fifty consecutive women undergoing oocyte retrieval were recruited. They un...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000158649
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:Qinba Mountain area of Shanxi Province, China, is one of the poorest, culturally backward regions in China with a high incidence of mental retardation. To investigate whether cytomegalovirus (CMV) plays a role in the high incidence of mental retardation in this region, we studied the incidence of CMV infectio...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000110013
更新日期:2008-01-01 00:00:00
abstract::The identification of immunoreactive beta-endorphin, beta-lipotropin and ACTH from extracts of human placentas by radioimmunoassay suggests a probable synthesis of these peptides in the placenta. In this study we investigated the presence of beta-endorphin and ACTH in placenta, amniotic membranes and umbilical cord us...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299023
更新日期:1985-01-01 00:00:00
abstract::Changes in norepinephrine following a bimanual handgrip contraction test were used to evaluate the contribution of static physical effort exerted by the parturient on the rise in adrenergic stimulation observed during ongoing labor. Noradrenaline baseline values were 306.71 +/- (SE) 21.5 pg/ml); and after a maximal ef...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298871
更新日期:1987-01-01 00:00:00
abstract::Breast involvement in ovarian cancer is extremely rare. We report a case of solitary breast metastasis from ovarian carcinoma in a 43-year-old white woman, 3 months following diagnosis of ovarian cancer. The diagnostic, therapeutic and prognostic aspects as well as a review of the literature of this uncommon site of m...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052946
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To describe three-dimensional (3-D) sonographic features of hydrops fetalis. METHODS:A total of 6 cases with hydrops fetalis from 15 to 32 weeks of gestation were studied with transabdominal 3-D sonography (3.5 MHz). RESULTS:Before around 20 weeks of gestation, the skin becomes a transparent-like structure,...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010167
更新日期:1999-01-01 00:00:00
abstract::In vitro production of progesterone and estradiol by human corpora lutea of different ages was evaluated in the presence or absence of human chorionic gonadotrophin (HCG). Progesterone production by the luteal tissue was enhanced by as little as 0.1 IU/ml HCG and maximally stimulated by approximately 10 IU/ml HCG. Est...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293698
更新日期:1988-01-01 00:00:00
abstract::Fetal echocardiographic and Doppler ultrasonographic prospective studies were performed in utero on 299 babies delivered at Hirata Municipal Hospital, Shimane, Japan, from May 1984 to June 1986. Two or three ultrasonographic examinations were performed on each fetus from 20 weeks of gestation to term. Three congenital...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293682
更新日期:1988-01-01 00:00:00
abstract::To assess the reliability of early biometric measurements in pregnancy, transvaginal sonography was performed in 92 pregnancies in the first trimester in a cross-sectional fashion. Measurements included crown-to-rump length (CRL), biparietal diameter (BPD), head and abdominal circumference (HC and AC), and femur lengt...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293032
更新日期:1991-01-01 00:00:00
abstract::Hot flushes are the commonest symptom induced by gonadotropin-releasing hormone agonists (GnRHa). We performed an open observational trial to evaluate the efficacy of veralipride, an antidopaminergic drug, in reducing hot flushes in 25 premenopausal women treated with a GnRHa for endometriosis (8 subjects) or menorrha...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000292736
更新日期:1992-01-01 00:00:00
abstract:AIM:The aim of this study was to evaluate whether natural fertility is related to serum 25-hydroxyvitamin D (25-OH-vitamin D) levels. METHODS:A nested case-control study was designed from a prospective cohort of pregnant women undergoing first trimester screening for aneuploidies. Cases included women seeking pregnanc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000443397
更新日期:2016-01-01 00:00:00
abstract::The relative roles of the cyclic nucleotide messengers cAMP and cGMP in the suppression of follicle-stimulating hormone (FSH) secretion in response to inhibin (IBN) were assessed employing rat gonadotropes in monolayer culture. While exposure of cells to gonadotropin-releasing hormone (GnRH) induced a significant incr...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298808
更新日期:1987-01-01 00:00:00
abstract::Semistructured interviews were made among a random sample of applicants for abortion in Stockholm, when legal abortion on demand had been available in Sweden for 10 years. One hundred and twenty women were interviewed, 75 of them having their first abortion and 45 having a repeat abortion. The use of contraceptives wa...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292572
更新日期:1994-01-01 00:00:00
abstract::This is a descriptive and cross-sectional study aiming to determine the factors affecting sexual life in pregnant women. The study was carried out in 238 women in Malatya, Turkey. It was found that 61.4% regarded coitus as a risk during pregnancy, 31.9% did not have any knowledge about this matter. In 81.5% sexual lif...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000075582
更新日期:2004-01-01 00:00:00
abstract::Omental pregnancy is a rare form of abdominal pregnancy. In the 5 previously reported cases, primary implantation of the embryo to the omentum has been proposed as its etiology. We present a new case of omental pregnancy in a 31-year-old woman presenting with symptoms of ectopic pregnancy. After careful review of our ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000291922
更新日期:1996-01-01 00:00:00
abstract::Acute intermittent porphyria is a rare autosomal dominant disease characterized by acute attacks of neuropsychiatric and neurovisceral dysfunction. In pregnancy, exacerbation of attacks in the form of seizures and acute abdomen occur due to hormonal changes. We report the case of a young woman presenting at 8 weeks of...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000091835
更新日期:2006-01-01 00:00:00
abstract::The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of e...
journal_title:Gynecologic and obstetric investigation
pub_type: 历史文章,杂志文章,评审
doi:10.1159/000343067
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:To test the hypothesis that obstetrical disseminated intravascular coagulopathy results from an excessive leakage of fetal material into the maternal circulation. METHODS:All peripartum hysterectomy cases for hemorrhage at two suburban Illinois hospitals over 10 years were included. Intravascular prese...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000332373
更新日期:2012-01-01 00:00:00
abstract::Estrogen (ER) - and progestagen (PgR) - receptors were estimated by a DCC method using Scatchard plot analysis In tissue samples of 68 patients with ovarian carcinomas. The mean ER and PgR levels were at 52 and 74 fmol/mg cytosol protein, respectively. ER+ PgR+ records were noted in 32.4%, ER+ PgR- in 26.4%, ER- PgR+ ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299256
更新日期:1983-01-01 00:00:00
abstract::Progesterone secretion of cultured human granulosa cells treated with LHRH or its analogues was measured. Granulosa cells were also stimulated with LH, FSH, cAMP or forskolin. No differences could be observed in the progesterone basal secretion of cultures treated with or without LHRH or its analogues and after the va...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292765
更新日期:1992-01-01 00:00:00
abstract::The morphological effect of a high-dose progestogen (Depo-Provera) on highly differentiated endometrial carcinoma was studied. Thirteen patients were treated by progestogen only, given at the beginning of the treatment in a weekly dose of 1,000 mg for 3 month. Then, progestogen 500 mg was administered for 12 months. N...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298812
更新日期:1987-01-01 00:00:00
abstract::The relationship between age and urodynamic parameters was studied cross-sectionally in a group of 28 women in whom clinically and urodynamically both stress incontinence and detrusor instability were excluded (no proven incontinence, NPI) and in a group, matched for age, with genuine stress incontinence (GSI). At all...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294858
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Pentraxin 3 (PTX3) is a novel vascular inflammatory marker which increases in vascular events such as diabetes mellitus. The aim of this study was to investigate the relationship between serum PTX3 levels and gestational diabetes mellitus (GDM). METHODS:This prospective observational study was comprised of ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000373889
更新日期:2015-01-01 00:00:00
abstract::A defect in placental function has been suggested to be associated both with preeclampsia (PE), with or without concomitant intrauterine growth retardation (IUGR), and with IUGR as a single entity. Our aim was to compare the mRNA expression of the growth-related protooncogenes c-fos and c-jun and the vasoconstrictor a...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291494
更新日期:1997-01-01 00:00:00