Abstract:
BACKGROUND/AIMS:To test the hypothesis that obstetrical disseminated intravascular coagulopathy results from an excessive leakage of fetal material into the maternal circulation. METHODS:All peripartum hysterectomy cases for hemorrhage at two suburban Illinois hospitals over 10 years were included. Intravascular presence of fetal material was determined by two pathologists blinded to each other and to any clinical information. For a given diagnosis, the percentage of intravascular fetal material in those patients with the diagnosis was compared with those without that diagnosis using Fisher's exact test. RESULTS:Seven diagnoses were attributed to the etiology of the hemorrhage: uterine rupture, abruption, uterine atony, placenta previa, accreta, coagulopathy, and retained placenta. Each of these diagnostic categories had fetal material present--ranging from 20 to 33%, but there were no statically significant differences. Secondary outcome measures of morbidity demonstrated that blood transfusion and intraoperative bladder injury were the chief comorbidities of peripartum hysterectomy. CONCLUSION:Maternal intravascular fetal material at the time of peripartum hysterectomy is present in up to one third of patients and does not invariably result in disseminated intravascular coagulopathy.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Benson MD,Cheema N,Kaufman MW,Goldschmidt RA,Beaumont JLdoi
10.1159/000332373subject
Has Abstractpub_date
2012-01-01 00:00:00pages
158-61issue
2eissn
0378-7346issn
1423-002Xpii
000332373journal_volume
73pub_type
杂志文章abstract:BACKGROUND:Cervical hydatidiform molar pregnancy is an exceedingly rare occurrence that has been reported only twice before. CASE:We report a 25-year-old, G4P1D&C2 woman with a positive pregnancy test and vaginal bleeding. A cervical pregnancy with hydatidiform mole was detected on transvaginal ultrasound and color Do...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000141647
更新日期:2008-01-01 00:00:00
abstract::Abdominal pregnancy is a very rare and serious type of extrauterine gestation that accounts for approximately 0.003% of all ectopic pregnancies. Omental pregnancy, an extremely rare form of abdominal pregnancy, can be primary or secondary to a tubal pregnancy that aborts out of the fimbria and reimplants in the perito...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000070188
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:Premature labor is still the leading cause of infant mortality and morbidity worldwide. Multiple etiological factors including genetics and environment are held responsible for preterm birth. However, scientific data regarding the link between premature birth and genetics are limited. SUBJECTS AND METHODS:In...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000237743
更新日期:2009-01-01 00:00:00
abstract::Ovarian lipid cell tumors are rare and can be difficult to localize by conventional means. We report a postmenopausal patient where rapid progression of symptoms and very high sebum levels suggested the presence of such a tumor which could not be visualized by computed tomography or ultrasound. Localization was accomp...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293633
更新日期:1989-01-01 00:00:00
abstract::Mesh of absorbable polyglactin 910 instead of human tissues or nonabsorbable synthetic materials was utilized for retropubic sling procedures in 21 women with urinary stress incontinence. The patients have been observed for a period ranging from 4 to 14 months. 20 of them are continent while there was 1 relapse after ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299212
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:Urinary bladder endometriosis is a severe form of endometriosis often requiring surgery. The several cases treated at our hospital in recent years has led us to evaluate the incidence of urinary bladder endometriosis in Finland. METHODS:We performed a register-based analysis of incidence of urinary bladder e...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000288161
更新日期:2010-01-01 00:00:00
abstract::Sixty postmenopausal women were randomly assigned to three types of treatment with intranasal salmon calcitonin (SCT) plus calcium 500 mg daily (group A: 100 IU daily of SCT; group B: 100 IU daily of SCT for alternate cycles of 2 months with a 1-month interval; group C: 100 IU daily of SCT for alternate cycles of 3 mo...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000294874
更新日期:1992-01-01 00:00:00
abstract::We present a case of leiomyomatosis peritonealis disseminata (LPD) after myoma morcellation and review the literature using the keywords leiomyomatosis peritonealis disseminata and disseminated peritoneal leiomyomatosis. The search was conducted in Medline, EMBASE, and Cochrane Database of systematic reviews. We encou...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000274487
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Human placentae from normal and pre-eclamptic pregnancies were evaluated for possible changes in gene expression by microarray analysis to uncover new clues for the research of the etiology of pre-eclampsia. METHODS:Placentae from five normal pregnancies and five pregnancies complicated by pre-eclampsia were...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092857
更新日期:2006-01-01 00:00:00
abstract::An aromatase inhibitor was identified in human follicular fluid. We sought to examine the effects of this inhibitor on granulosa cells, theca cells, a mixture of granulosa and theca cells, and follicles. Granulosa cells, theca cells, the mixture of granulosa and theca cells, and follicles were incubated with [3H]-thym...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292692
更新日期:1993-01-01 00:00:00
abstract::Therapeutic abortion by vacuum aspiration in the first trimester was carried out on 129 healthy multigravid women. The loss of haemoglobin at operation was estimated and the volume of blood calculated. The figures were compared to those in a group of primigravid women earlier reported. Blood loss increases with gestat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000300997
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Pentraxin 3 (PTX3) is a novel vascular inflammatory marker which increases in vascular events such as diabetes mellitus. The aim of this study was to investigate the relationship between serum PTX3 levels and gestational diabetes mellitus (GDM). METHODS:This prospective observational study was comprised of ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000373889
更新日期:2015-01-01 00:00:00
abstract::Semistructured interviews were made among a random sample of applicants for abortion in Stockholm, when legal abortion on demand had been available in Sweden for 10 years. One hundred and twenty women were interviewed, 75 of them having their first abortion and 45 having a repeat abortion. The use of contraceptives wa...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292572
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Group B streptococcus (GBS) is an important cause of neonatal sepsis. Guidelines advise to collect cultures at 35-37 weeks' gestation and to administer intrapartum antibiotic prophylaxis in case of GBS-positive cultures, as well as in all preterm deliveries. Improved effectiveness of antenatal cultures might...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000265942
更新日期:2010-01-01 00:00:00
abstract::The 784 cases, from which 701 complained of abnormal uterine bleeding, were reviewed by age groups, presenting symptoms, sex steroid medication and endometrial findings. Endometrial polyps and endometritis, which showed an incidence of 17.5 and 10.0%, respectively, were correlated with clinicopathologic findings. Peri...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299980
更新日期:1979-01-01 00:00:00
abstract::Breast involvement in ovarian cancer is extremely rare. We report a case of solitary breast metastasis from ovarian carcinoma in a 43-year-old white woman, 3 months following diagnosis of ovarian cancer. The diagnostic, therapeutic and prognostic aspects as well as a review of the literature of this uncommon site of m...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052946
更新日期:2001-01-01 00:00:00
abstract::Estrogen (ER) - and progestagen (PgR) - receptors were estimated by a DCC method using Scatchard plot analysis In tissue samples of 68 patients with ovarian carcinomas. The mean ER and PgR levels were at 52 and 74 fmol/mg cytosol protein, respectively. ER+ PgR+ records were noted in 32.4%, ER+ PgR- in 26.4%, ER- PgR+ ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299256
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND/AIMS:The transmembrane protein dystroglycan (DG) is known to anchor the cell membrane to the extracellular matrix, and is susceptible to cleavage by matrix metalloproteinases. This study tested the hypothesis that changes in DG abundance in fetal membranes (FM) occur late in gestation, with spontaneous ruptu...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000367894
更新日期:2015-01-01 00:00:00
abstract::The identification of immunoreactive beta-endorphin, beta-lipotropin and ACTH from extracts of human placentas by radioimmunoassay suggests a probable synthesis of these peptides in the placenta. In this study we investigated the presence of beta-endorphin and ACTH in placenta, amniotic membranes and umbilical cord us...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299023
更新日期:1985-01-01 00:00:00
abstract::ABO blood group was analyzed in 70 patients with hydatidiform mole and 53 patients with malignant trophoblastic disease. 319 healthy pregnant women served as controls. The distribution of ABO blood groups in patients with hydatidiform mole did not deviate significantly from the distribution in the controls. There was ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298967
更新日期:1985-01-01 00:00:00
abstract::25 singleton pregnancies were terminated by cesarean section between 28 and 33 weeks of gestation because of suspected growth retardation and abnormal unstressed cardiotocograms. Only infants with birth weights below the tenth centile were considered. 17 survived and were neurologically examined at 2.5-7 years of age....
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299030
更新日期:1985-01-01 00:00:00
abstract::Human heparanase has been shown to function in tumor progression, metastatic spread, and tumor angiogenesis. The aim of the present study was to assess heparanase expression in endometrial cancer in correlation with neovascularization and clinicopathological factors. Forty endometrial cancers were obtained from previo...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000072821
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:This study is aimed at comparing the early diagnostic accuracy of maternal blood white blood cell (WBC) count, C-reactive protein (CRP) and procalcitonin in predicting early onset neonatal sepsis (EONS) among early preterm premature rupture of membrane (PPROM) pregnancies. METHODS:A total of 57 consecutive ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000446949
更新日期:2017-01-01 00:00:00
abstract::We present the case of a female fetus aborted in the 20th week of gestation due to severely dysplastic kidneys, anhydramnios and hydranencephalus. The combination of these malformations is extremely rare, resulting in only 4 cases described so far. Our case is the first ever presented in a female showing polycystic-dy...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000291522
更新日期:1997-01-01 00:00:00
abstract::Acupuncture treatment in the final weeks of pregnancy has been claimed to shorten the duration of labor in primiparous women. In the present study, the length of the various phases of labor was calculated for 56 primiparous women who were repeatedly treated with manual acupuncture during the month prior to parturition...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298806
更新日期:1987-01-01 00:00:00
abstract::Pelvic masses can be diagnosed by pelvic ultrasonography. Difficulties may be encountered to identify the organ origin of a pelvic mass. An intrauterine marker is proposed to facilitate the diagnosis by the exact localization of the uterus and its relationship to other pelvic findings. ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298777
更新日期:1987-01-01 00:00:00
abstract::Deep dyspareunia, often described as pain resulting from pelvic thrusting during sexual intercourse, is relatively common and has many causes. To date, feasible surgical interventions for deep dyspareunia are very rare. The two procedures which have been mentioned in the literature for the treatment of deep dyspareuni...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000087562
更新日期:2006-01-01 00:00:00
abstract::The rate of spontaneous and methotrexate (MTX)-induced chromosome breakage was studied in individuals with a history of habitual abortions in whom a structural chromosomal aberration was found in a single cell during routine cytogenetic analysis. Twelve such individuals were selected because they were not under the in...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292599
更新日期:1993-01-01 00:00:00
abstract::Bone turnover in pregnant women with McCune-Albright syndrome may be affected by both the syndrome and pregnancy. This study evaluated changes in biochemical bone turnover markers in pregnant women with the syndrome. Serum calcium, phosphorus, 1,25-dihydroxyvitamin D (1,25-(OH)2D), intact osteocalcin (I-OC) and alkali...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000085535
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate patient satisfaction after laparoscopic supracervical (LASH) or total hysterectomy (TLH). METHODS:Retrospective study of patient satisfaction after LASH or TLH. RESULTS:We studied 40 cases of LASH and another 40 of TLH. The age of the patients, marital status, education level and employmen...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000184679
更新日期:2009-01-01 00:00:00