Investigation of beta-endorphin and adrenocorticotropic hormone in placenta, amniotic membrane and umbilical cord using an immunoperoxidase technique.

Abstract:

:The identification of immunoreactive beta-endorphin, beta-lipotropin and ACTH from extracts of human placentas by radioimmunoassay suggests a probable synthesis of these peptides in the placenta. In this study we investigated the presence of beta-endorphin and ACTH in placenta, amniotic membranes and umbilical cord using a peroxidase-antiperoxidase staining technique. Tissues were obtained immediately after delivery, fixed in formalin and embedded in paraffin. As control tissues autopsy specimens of pituitary glands from adults and newborns were used. All sections of pituitary glands showed a positive reaction; negative results were observed in sections of placentas, umbilical cords and amniotic membranes. We conclude that no intracellular storage of beta-endorphin and ACTH takes place in the examined tissues.

journal_name

Gynecol Obstet Invest

authors

Reinthaller A,Riss P

doi

10.1159/000299023

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

135-8

issue

3

eissn

0378-7346

issn

1423-002X

journal_volume

19

pub_type

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