Serum-specific antibodies for Chlamydia trachomatis in preterm premature rupture of the membranes.

Abstract:

:A case control study was performed to examine possible morbidity associated with Chlamydia trachomatis in 15 pregnant women with idiopathic preterm premature rupture of the membranes (PROM; group A), and in two control groups, 35 healthy preterm pregnant women (group B), and 43 healthy pregnant women at term (group C). Serum C. trachomatis IgG and IgA specific antibodies were determined using the single serovar (L2) inclusion immunoperoxidase assay. There were no significant differences in the prevalence rate of elevated levels of chlamydia IgG specific antibodies (titer greater than or equal to 1:128) between pregnant women suffering from idiopathic preterm PROM, as compared to healthy preterm and term pregnant women (20, 28 and 26%, respectively). Nor were there any significant differences in the prevalence rate of elevated levels of chlamydia IgA specific antibodies (titer greater than or equal to 1:16) between pregnant women with idiopathic preterm PROM, as compared to healthy preterm and term pregnant women (20, 20 and 17%, respectively). These findings do not support the assumption that C. trachomatis may play role in preterm PROM.

journal_name

Gynecol Obstet Invest

authors

Cohen I,Tenenbaum E,Fejgin M,Michaeli G,Beyth Y,Sarov I

doi

10.1159/000293249

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

155-8

issue

3

eissn

0378-7346

issn

1423-002X

journal_volume

30

pub_type

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