Treatment of metastatic uterine leiomyosarcoma with cisplatin, pirarubicin, and ifosfamide.

Abstract:

:We present the unusual case of a 27-year-old Japanese woman who exhibited recurrences of metastatic tumors from uterine leiomyosarcoma after five operations. Chemotherapy with cisplatin, pirarubicin, and cyclophosphamide was ineffective. Substituting ifosfamide for cyclophosphamide, we obtained a complete response. The Gynecologic Oncology Group (GOG) in the United States has recognized the efficacy of ifosfamide and mesna in the treatment of patients with advanced or recurrent uterine sarcomas. Here we report on the efficacy of ifosfamide in addition to cisplatin and pirarubicin.

journal_name

Gynecol Obstet Invest

authors

Hirota Y,Miyamura K,Hayata T,Miyakawa I

doi

10.1159/000291415

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

70-2

issue

1

eissn

0378-7346

issn

1423-002X

journal_volume

44

pub_type

杂志文章
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    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000052955

    authors: Bonacho I,Pita S,Gómez-Besteiro MI

    更新日期:2001-01-01 00:00:00

  • Persistence of Lactobacilli in Postmenopausal Women - A Double-Blind, Randomized, Pilot Study.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,评审

    doi:10.1159/000446946

    authors: Kwak YK,Daroczy K,Colque P,Kühn I,Möllby R,Kopp Kallner H

    更新日期:2017-01-01 00:00:00

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000068381

    authors: Dong M,Xie X,Wang Z,He J,Zhou J,Cheng Q

    更新日期:2002-01-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1159/000293507

    authors: Başer I,Dilek S,Pabuçcu R,Ulgenalp I,Mermut S,Finci R

    更新日期:1989-01-01 00:00:00

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000074451

    authors: Darwish A

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  • Do patients prefer a pessary or surgery as primary treatment for pelvic organ prolapse.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000336634

    authors: Thys SD,Roovers JP,Geomini PM,Bongers MY

    更新日期:2012-01-01 00:00:00

  • Estrogen and progesterone receptor expression of decidual endometrium in a postmenopausal woman treated with tamoxifen and megestrol acetate.

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    pub_type: 杂志文章

    doi:10.1159/000292464

    authors: Cohen I,Shulman A,Altaras M,Tepper R,Cordoba M,Beyth Y

    更新日期:1994-01-01 00:00:00

  • Peritoneal fluid leukotriene B4 and prostaglandin E2 in acute salpingitis.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293338

    authors: Heinonen PK,Aine R,Seppälä E

    更新日期:1990-01-01 00:00:00

  • Involvement of phenotypes and serum levels of haptoglobin in the outcome of in vitro fertilization and embryo transfer.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000058053

    authors: Ueda K,Yamamasu S,Nakamura Y,Honda K,Ozaki K,Fujino Y,Ishiko O,Ogita S

    更新日期:2001-01-01 00:00:00

  • Materno-fetal transmission of pregnancy malaria: an immunoparasitological study on 202 parturients in Maputo.

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    pub_type: 杂志文章

    doi:10.1159/000292675

    authors: Bergström S,Fernandes A,Schwalbach J,Perez O,Miyar R

    更新日期:1993-01-01 00:00:00

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293093

    authors: Kokia E,Dor J,Blankenstein J,Seidman DS,Lipitz S,Serr DM,Mashiach S

    更新日期:1991-01-01 00:00:00

  • The stromal architecture of the immature intermediate villus of the human placenta. Functional and clinical implications.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299056

    authors: Castellucci M,Schweikhart G,Kaufmann P,Zaccheo D

    更新日期:1984-01-01 00:00:00

  • Serial transvaginal sonography of a case of complete hydatidiform mole.

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    pub_type: 杂志文章

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  • Prediction of high birthweight from maternal characteristics, symphysis fundal height and ultrasound biometry.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292658

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    更新日期:1993-01-01 00:00:00

  • Management of supraventricular tachycardia during hexoprenaline therapy for preterm labour: benefit of cardioselective beta blockade?

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292411

    authors: Frigo P,Eppel W,Frank A,Ulm M,Golaszewski T,Gruber W

    更新日期:1995-01-01 00:00:00

  • Metronidazole and facultative anaerobes.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000300975

    authors: Pohunek M,Frintová K

    更新日期:1978-01-01 00:00:00

  • Effect of danazol and ovariectomy on matrix metalloproteinases in rat uteri.

    abstract::The experiments described in this report were designed to study the effects of danazol on matrix metalloproteinases in the rat uterus. Proteinases were analyzed by zymography in gels copolymerized with either gelatin or transferrin. There were no apparent effects of danazol on proteinases from rat uteri when analyzed ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010218

    authors: Willingham AK

    更新日期:2000-01-01 00:00:00

  • Testicular feminization syndrome in the neonate.

    abstract::If we see a young, phenotypically female patient with an XY karyotype, it is of great importance to differentiate between the testicular feminization syndrome and gonadal dysgenesis. Patients with testicular feminization will always have normal testes, which are situated either in the ovarian fossa or in the inguinal ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293367

    authors: van Zijl JA,Evers JL,Gerver WJ

    更新日期:1990-01-01 00:00:00

  • In vitro fertilization in Kock's ileostomy patients. Prior evaluation by pelvic ultrasonography.

    abstract::The study describes Kock's continent ileostomy in 2 females, both of whom were suffering from tubal infertility. Appropriate placement of the abdominal pouch, permitting in vitro fertilization embryo transfer treatment, was present in 1 patient. In the other patient, an ultrasonographic examination demonstrated the po...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293324

    authors: Dor J,Shalev J,Shoham Z,Rabau M,Rudak E,Serr DM,Mashiach S

    更新日期:1990-01-01 00:00:00

  • The lunar cycle and the number of deliveries in Austria between 1970 and 1999.

    abstract::The effect of the moon on the number of newborns has been investigated extensively with contradictory results but with few significant findings. In this paper, a possible lunar effect is analyzed by a nonlinear Poisson regression model similar to a Fourier analysis based on all children (n = 2,760,362) born in Austria...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000052999

    authors: Waldhoer T,Haidinger G,Vutuc C

    更新日期:2002-01-01 00:00:00

  • Placental proteins in male serum.

    abstract::Placental proteins such as human chorionic gonadotrophin (hCG), Schwangerschaftsprotein 1 (SP1) and pregnancy-associated plasma protein A (PAPP-A) are found in the blood of pregnant women and in subjects suffering from cancer. They can also be found in the blood of healthy non-pregnant women and in the seminal fluid o...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000298985

    authors: Klopper A,Ahmed AG,Bersinger N,Urbaniak S

    更新日期:1985-01-01 00:00:00

  • Proteoglycans from cultures of fibroblast from the human uterine cervix.

    abstract::A small dermatan sulphate proteoglycan has been isolated from the human uterine cervix. The concentration of this proteoglycan has been shown to decrease during pregnancy. To study the mechanism behind this change fibroblasts from the human uterine cervix were established in culture. Their synthesis and secretion of p...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299026

    authors: Uldbjerg N,Malmström A,Ekman G,Ulmsten U

    更新日期:1985-01-01 00:00:00

  • Attitudes and compliance with research requirements in OB/GYN residencies: a national survey.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000348562

    authors: Oakley SH,Crisp CC,Estanol MV,Fellner AN,Kleeman SD,Pauls RN

    更新日期:2013-01-01 00:00:00

  • Ureteral blockage as a complication of Burch colposuspension: report of 6 cases.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293398

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    更新日期:1990-01-01 00:00:00

  • Magnetic resonance imaging angiography in a case of eclampsia.

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    pub_type: 杂志文章

    doi:10.1159/000292595

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    更新日期:1993-01-01 00:00:00

  • Ovarian morphology in patients with polycystic ovaries and in an age-matched reference material. A statistical evaluation of 149 cases.

    abstract::The ovarian morphology in 149 patients with the clinical syndrome of polycystic ovaries (group I) is described. The ovaries from 10 age-matched women (group II) with no signs of ovarian disorder were investigated as a reference material. The number of cysts documented for group I was twice that of the reference group ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293771

    authors: Lunde O,Hoel PS,Sandvik L

    更新日期:1988-01-01 00:00:00

  • Effects of add-back therapy on bone mineral density and pyridinium crosslinks in patients with endometriosis treated with gonadotropin-releasing hormone agonists.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000010059

    authors: Gnoth CH,Gödtke K,Freundl G,Godehardt E,Kienle E

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  • Three-dimensional sonographic features of Hydrops fetalis.

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010167

    authors: Hata T,Yanagihara T,Matsumoto M,Hanaoka U,Maesato T,Tanaka Y,Kuno A,Akiyama M,Yamashiro C,Ohnishi Y,Tanaka H,Hayashi K,Yamada Y

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  • Is There a Benefit to Culturing Intra-Uterine Devices in Pelvic Inflammatory Disease?

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    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000490666

    authors: Fouks Y,Many A,Amit S,Levin I,Meiri A,Shinar S

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    pub_type: 杂志文章

    doi:10.1159/000098198

    authors: Shiba M,Kikuchi A,Hara K,Sunagawa S,Yoshida S,Takagi K,Ogiso Y

    更新日期:2007-01-01 00:00:00