A rabbit model of endometriosis.

Abstract:

:Since not all problems in endometriosis can be studied in the human, there is need of an animal model. We transplanted endometrial tissue of the rabbit into the peritoneal cavity and studied the changes after 12 weeks. At that time the endometrial implants in the rabbit had become cystic structures. The macroscopic and histologic appearance was consistent with endometriosis. Hormonal supplementation turned out not to be necessary. Microsurgical techniques prevented the formation of tubo-ovarian adhesions. This makes the rabbit model suitable for studying the influence of endometrial implants on fertility.

journal_name

Gynecol Obstet Invest

authors

Dunselman GA,Willebrand D,Land JA,Bouckaert PX,Evers JL

doi

10.1159/000293611

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

29-33

issue

1

eissn

0378-7346

issn

1423-002X

journal_volume

27

pub_type

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