Abstract:
:In vitro experiments using isolated rings and perfused segments of human chorionic veins, were designed to determine the effects of serotonin and their interaction with PGF2 alpha on vascular tension and perfusion pressure. These vessels responded vigorously with high sensitivity to the vasoconstrictor effects of serotonin in both experimental designs. Administration of PGF2 alpha also led to constriction of the veins, but this autacoid is at least 100 times less potent than serotonin. When adding PGF2 alpha previously to serotonin to the bathing fluid or to the perfusate, the serotonin response was significantly potentiated, increasing the maximal contractile response in 116 +/- 12% and the perfusion pressure in 180 +/- 25%. Both autacoids probably operate in this vascular bed interacting with each other and playing an important role in the regulation of placental blood flow in vivo.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
González C,Cruz MA,Gallardo V,Albornoz J,Bravo Idoi
10.1159/000292671subject
Has Abstractpub_date
1993-01-01 00:00:00pages
86-90issue
2eissn
0378-7346issn
1423-002Xjournal_volume
35pub_type
杂志文章abstract::In a prospective clinical investigation of 2,144 deliveries, we elucidate the indications for episiotomy and how different methods of anesthesia affect the frequency of episiotomy and the perineal problems after episiotomy compared with those after spontaneous perineal laceration. We found a significantly higher infec...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293161
更新日期:1991-01-01 00:00:00
abstract::Progesterone secretion of cultured human granulosa cells treated with LHRH or its analogues was measured. Granulosa cells were also stimulated with LH, FSH, cAMP or forskolin. No differences could be observed in the progesterone basal secretion of cultures treated with or without LHRH or its analogues and after the va...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292765
更新日期:1992-01-01 00:00:00
abstract:AIMS:The study aimed to compare the clinical course and disease severity between culture positive and culture negative patients with intra-uterine devices (IUD)-associated pelvic inflammatory disease (PID). METHODS:A retrospective study of all IUD-associated PID patients admitted to tertiary medical center between 201...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000490666
更新日期:2019-01-01 00:00:00
abstract::The objective of the present study was to compare the rate of embryo cleavage after oocyte insemination with capacitated spermatozoa in the presence or absence of follicular fluid. In the first experiment, a total of 67 oocytes were inseminated with spermatozoa which had been submitted to part of the capacitation proc...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292545
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND/AIMS:Pregnancy complicated by diabetes is associated with increased risk of unfavorable obstetric outcomes. A common abnormality in diabetes is endothelial dysfunction resulting in an altered pattern of vasoactive substance production by the endothelial cells. The aim of study was to assess serum endothelin-...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000253851
更新日期:2010-01-01 00:00:00
abstract::Minimal deviation adenocarcinoma (MDA) is a very rare variant of cervical adenocarcinoma, this pathological entity is composed of mucinous very-well-differentiated glands deeply invading cervical stroma, and often surrounded by a desmoplastic reaction. Despite its benign histological appearance, MDA is typically chara...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000327938
更新日期:2011-01-01 00:00:00
abstract::The level of human fibronectin receptor (FNR) in plasma was measured by enzyme-linked immunosorbent assay in samples from normal pregnant women in the 1st trimester (n = 5), 2nd trimester (n = 7), 3rd trimester (n = 23), normal postpartum women day 1 (n = 4), day 2 (n = 5), day 3 (n = 8), nonpregnant women (n = 18), 2...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294869
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To analyze the effects and potential benefits of a single midcycle dose of follicle-stimulating hormone (FSH) prior to human chorionic gonadotropin (hCG) administration during unstimulated in vitro fertilization (IVF) cycles. METHODS:Twenty-five cycles from 20 patients receiving 150 IU of FSH 42-44 h and 10,00...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291825
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:MIB 1 is a new monoclonal antibody which recognizes nuclei of proliferating cells throughout the cell cycle except during the G0 and early G1 phases. In the present study we analyzed the MIB 1 immunostaining as an index of cellular proliferation in cervical intraepithelial neoplasia (CIN) and microinvasive ca...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291977
更新日期:1996-01-01 00:00:00
abstract::The relative fatty acid composition of serum lecithin was followed in groups of women during postmenopausal replacement therapy. The effects of estradiol valerate and ethinyl estradiol in two different doses, and the modulating influence of various progestogens and antiestrogens were compared. Unopposed estrogen treat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299096
更新日期:1984-01-01 00:00:00
abstract::Amniotic fluids from women in West Virginia were evaluated for the presence of antibacterial activity by a bioassay technique. 41% of 32 third trimester samples were inhibitory. Evaluation of additional test organisms emphasized differences in susceptibility of various bacterial strains; two isolates of Escherichia co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299390
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to investigate the in vivo magnetic resonance spectroscopy features of uterine leiomyomas using long echo time and to characterize the spectral patterns of these lesions. METHODS:We calculated metabolites in 15 patients with uterine leiomyomas and myometrium of 20 healthy control...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000080020
更新日期:2004-01-01 00:00:00
abstract::Choriocarcinoma coexistent with an intrauterine pregnancy is rare and requires decisions affecting mother and child to treat this aggressive tumor. An instance of this situation is presented to highlight clinical circumstances that warrant departure from accepted dogma. Pathologic aspects of choriocarcinoma are also d...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000363234
更新日期:2015-01-01 00:00:00
abstract::Changes in norepinephrine following a bimanual handgrip contraction test were used to evaluate the contribution of static physical effort exerted by the parturient on the rise in adrenergic stimulation observed during ongoing labor. Noradrenaline baseline values were 306.71 +/- (SE) 21.5 pg/ml); and after a maximal ef...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298871
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To investigate normal human placental growth longitudinally throughout the second and third trimesters using MRI. METHODS:Twenty normal, first-time singleton pregnancies were scanned 7 times between the 14th and 38th week of gestation, at 4-week intervals, using MRI. Placental volumes were measured in both s...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000452661
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:This study aims to establish a model to measure the forces required for tension-free vaginal tape (TVT) trocar application using a pressure transducer. METHODS:A 3.5 x 3.5 cm pressure transducer was constructed from piezo-resistive material. The transducer digitally recorded the surface contact pressur...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092641
更新日期:2006-01-01 00:00:00
abstract::A prospective randomized trial comprising 90 patients was undertaken to evaluate three different regimens of tinidazole in the treatment of anaerobic vaginosis. Each group consisted of 30 women. The three regimens were: (A) oral tinidazole (150 mg X 2) for 7 days, (B) same oral treatment as above but also the partner ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000293524
更新日期:1989-01-01 00:00:00
abstract::Anterior colporrhaphy (Kelly-Stoeckel suture) was performed on 22 women suffering from grade-I or grade-II genuine stress incontinence. Urodynamic investigation was performed on every patient before surgery and 6 months postoperatively. 21 patients were cured and 1 patient improved. After operation the functional uret...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010196
更新日期:1999-01-01 00:00:00
abstract:AIMS:To evaluate the efficacies of the estrogen receptor-alpha (ER-alpha) gene polymorphisms and of the intrafollicular insulin-like growth factor (IGF) system for predicting pregnancy in in vitro fertilization and embryo transfer (IVF-ET) patients. METHODS:A total of 96 patients undergoing IVF-ET were included in thi...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000162104
更新日期:2009-01-01 00:00:00
abstract::Digoxin-like immunoreactive substance (DLIS) has been proposed to have a role in what seems to be the timely onset of labor. The relationship between the DLIS in patients with preterm labor and the success of tocolytic therapy with ritodrine and nifedipine has been studied. Using a commercially available radioimmunoas...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292511
更新日期:1994-01-01 00:00:00
abstract::Fetal weight prediction with ultrasonic measurements of biparietal diameter (BPD) and abdominal circumference (AC) using the equation by Shepard et al. [1982] was tested prospectively in 310 fetuses. Fetuses of all weight categories were included. The error of weight prediction was in the range of +684 to -880 g. One ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298895
更新日期:1986-01-01 00:00:00
abstract:AIM:To determine factors associated with intrapartum fever and to examine associated maternal and neonatal outcomes. METHODS:Retrospective study of patients between 360/7 and 420/7 gestational weeks who entered spontaneous or induced active labor and developed temperature ≥38°C; a similar group that did not develop fe...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000453611
更新日期:2017-01-01 00:00:00
abstract::A case control study was performed to examine possible morbidity associated with Chlamydia trachomatis in 15 pregnant women with idiopathic preterm premature rupture of the membranes (PROM; group A), and in two control groups, 35 healthy preterm pregnant women (group B), and 43 healthy pregnant women at term (group C)...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000293249
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Genetic factors may play a role in male infertility. METHODS:In a prospective case-control study, we assessed the allele and genotype frequencies of the TNFalpha -308 C-->T and -863 C-->A polymorphisms, detected by PCR of sperm DNA, of 577 Caucasian men recruited in an infertility clinic. Semen sampling was...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000126494
更新日期:2008-01-01 00:00:00
abstract:AIMS:The study aimed to assess the diagnostic value of serial monitoring of biochemical inflammatory markers (C-reactive protein (CRP) and white blood cell (WBC) count) in the postoperative diagnosis of anastomotic leakage or ureteral injury after bowel resection for deep infiltrating endometriosis. METHODS:This is a ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000447513
更新日期:2017-01-01 00:00:00
abstract::A decade of perinatal audit in the Maputo Central Hospital is reviewed with the objective of addressing the potential value of the audit process in monitoring the different constituents of morbidity and mortality in the perinatal period. The perinatal mortality showed a significant but transient change during the obse...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292637
更新日期:1993-01-01 00:00:00
abstract::Alleviation of infertility on the one hand and development of improved methods of contraception on the other are global concerns to woman's health. The molecular signals that regulate implantation are of clinical relevance since understanding the nature of these signals may lead to strategies to correct implantation f...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000076761
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND/AIMS:Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and well-being. The pathophysiology and epidemiology of fibroids are poorly understood. Obesity and elevated blood pressure have been reported to be predisposing factors. In this study, we investigat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000114250
更新日期:2008-01-01 00:00:00
abstract::The correlation between arousal state and fetal habituation was tested. Four behavioral states were determined according to fetal heart activity and movement pattern in 52 fetuses. Repeated wide low-frequency sound was used as external stimulus. Ceasing of response to 5 consecutive stimuli indicated habituation. The t...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293315
更新日期:1990-01-01 00:00:00
abstract::This study was conducted to determine the accuracy of frozen section diagnosis in borderline ovarian tumors. Thirty-three patients were evaluated on the basis of frozen sections between February 1992 and December 1997. Frozen section diagnosis and final diagnosis were divided into three categories: for frozen section ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010244
更新日期:2000-01-01 00:00:00