Abstract:
:In a prospective clinical investigation of 2,144 deliveries, we elucidate the indications for episiotomy and how different methods of anesthesia affect the frequency of episiotomy and the perineal problems after episiotomy compared with those after spontaneous perineal laceration. We found a significantly higher infection rate (p less than 0.001) and a longer healing period in the episiotomy group. These differences remain even if only primigravida or the indication, imminent perineal laceration, is studied. The results indicate that many women will unnecessarily suffer after an episiotomy. The patient's subjective problems are significantly increased, both immediately and at the 3-month postoperative follow-up.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Larsson PG,Platz-Christensen JJ,Bergman B,Wallstersson Gdoi
10.1159/000293161subject
Has Abstractpub_date
1991-01-01 00:00:00pages
213-6issue
4eissn
0378-7346issn
1423-002Xjournal_volume
31pub_type
杂志文章abstract:OBJECTIVE:To evaluate the efficacy of depot medroxy progesterone acetate (DMPA) as a preparatory agent for endometrial resection. STUDY DESIGN:Endometrial resection was performed on 50 women for excessive uterine bleeding. The patients were randomly divided into 2 equal groups, with the first group receiving DMPA and ...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000052969
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To investigate the expression of T-cell immunoglobulin and mucin domain 3 (TIM-3) on peripheral T cells of cervical carcinoma patients. METHODS:Peripheral blood samples from 15 high-grade cervical squamous intraepithelial lesion (HSIL) patients, 24 cervical carcinoma patients, and 21 healthy controls were co...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000511440
更新日期:2020-12-04 00:00:00
abstract:BACKGROUND:Little is known about proper interval periods between the flushings of totally implantable access ports after completion of chemotherapy. Manufacturer guidelines recommend flushing catheters every 4 weeks. METHODS:This retrospective study examined whether flushing less than every 4 weeks conferred any benef...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294919
更新日期:2010-01-01 00:00:00
abstract::The influence of phenazone on the production of prostacyclin and thromboxane in human umbilical arteries was investigated by in vitro perfusion. With perfusate concentrations ranging from 10(-7) to 10(-4) M a decrease in the formation of both prostanoids was observed. The inhibitory effect of phenazone on prostanoid f...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292366
更新日期:1995-01-01 00:00:00
abstract::We have previously shown a marked diurnal variation in the excretion of cortisol and 6 beta-hydroxycortisol at 36-38 weeks pregnancy with no variation in estrogen excretion. Since others have shown a reciprocal relationship between plasma levels of estriol and cortisol at 30-35 weeks of pregnancy, we decided to determ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298855
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To perform a health economics analysis of 5 screening programs for osteoporosis in perimenopausal Thai women comparing two alternatives; without intervention and universal treatment without screening. DESIGN:A decision analysis was performed to evaluate five screening strategies: Dual energy X-ray absorptiom...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092803
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To assess the presence of human papillomavirus (HPV) DNA in vulvar papillomatosis, since some women with this complaint have symptoms associated with HPV infection, such as itching, burning, and dyspareunia. GOAL:To reassure the patients that they do not have a transmissible viral disease, by...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292350
更新日期:1995-01-01 00:00:00
abstract::The diagnosis of vulvo-vaginal complaints has always been enigmatic in obstetrics and gynecology. Patients with clear, pathognomonic symptoms end up with a proper diagnosis and treatment most of the time, but unfortunately we are now living in a world where women reach out to the Internet and readily get all informati...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000478982
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:Adenomyosis is a common condition with a poorly understood pathogenesis. Recent data suggest that it may be an epigenetic disease. This study investigated the expression and localization of class I histone deacetylases (HDACs) in women with and without adenomyosis. METHODS:The ectopic and homologous eu...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000336409
更新日期:2012-01-01 00:00:00
abstract::Ciliary neurotrophic factor (CNTF) is a gp130 neuroregulatory cytokine belonging to the interleukin-6-type cytokine superfamily. Several lines of evidence suggest that the concentrations of interleukin-6 are elevated in the peritoneal fluid of endometriosis patients. To our knowledge, no study on whether this might al...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000072694
更新日期:2003-01-01 00:00:00
abstract::A factor present in the serum of pregnant women is able to inhibit nonspecifically a cellular cytotoxicity reaction. This glycoprotein called P4, is an alpha-globulin whose molecular weight is 200,000 daltons bound to albumin. Its isoelectric point is 4.1. By its various characteristics, P4 seems different from other ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298991
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate patient satisfaction after laparoscopic supracervical (LASH) or total hysterectomy (TLH). METHODS:Retrospective study of patient satisfaction after LASH or TLH. RESULTS:We studied 40 cases of LASH and another 40 of TLH. The age of the patients, marital status, education level and employmen...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000184679
更新日期:2009-01-01 00:00:00
abstract::Oviducts of 35 mature, white New Zealand rabbits were injured by a laser beam, using various powers from 25 to 40 W, and by a series of pulses of 1/10, 1/20 or 1/100 s duration. The contralateral oviducts served as controls and were injured at similar areas by a scalpel. The injured areas of both tubes were histologic...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299610
更新日期:1981-01-01 00:00:00
abstract::Thirty-four perimenopausal women with uterine leiomyomas were treated with intramuscular injections of leuprolide acetate depot each 28 days for 6 cycles, and 12 of them after 168 days of no medication underwent a second 6-month therapy cycle. At the end of the observation period the expected improvement during treatm...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292391
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of our study was to evaluate the prevalence of abuse among pregnant women in Germany attending our antenatal outpatient clinic and to observe whether a history of abuse had consequences for women's feelings about their pregnancy. METHODS:455 women between the 35th and 42nd weeks of gestational ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000215931
更新日期:2009-01-01 00:00:00
abstract::An aromatase inhibitor was identified in human follicular fluid. We sought to examine the effects of this inhibitor on granulosa cells, theca cells, a mixture of granulosa and theca cells, and follicles. Granulosa cells, theca cells, the mixture of granulosa and theca cells, and follicles were incubated with [3H]-thym...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292692
更新日期:1993-01-01 00:00:00
abstract::Alternations of the pelvic structure with an emphasis on those of the levator ani muscle, associated with uterine prolapse, were studied using sagittal magnetic resonance images obtained from 19 subjects without and 14 with uterine or vaginal prolapse of varied degree and 3 patients with Rokitansky syndrome who had un...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292723
更新日期:1992-01-01 00:00:00
abstract::Vaginal adenosis is rare, and it is defined as the presence of metaplastic cervical or endometrial epithelium within the vaginal wall. It is associated with in utero exposition to diethylstilbestrol and a high risk of vaginal carcinomas. A case of vaginal adenosis arising in a non-diethylstilbestrol-exposed 6-year-old...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000058063
更新日期:2001-01-01 00:00:00
abstract:AIM:To investigate the ability of lactobacilli to persist in the genital area (vagina and labia) of women after the topical application of an ointment containing Lactobacillus gasseri LN40, L. fermentum LN99 and L. rhamnosus LN113. Secondary objectives were to study the presence of Escherichia coli and other contaminan...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,评审
doi:10.1159/000446946
更新日期:2017-01-01 00:00:00
abstract::To test the effects of calcium dobesilate (Doxium) in pregnancies complicated with pregnancy-induced hypertension or mild/moderate pre-eclampsia a double-blind, placebo-controlled pilot study was carried out. Primigravida patients (gestational age =34 weeks) daily took 2 g Doxium or placebo until delivery. Twelve pa...
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000010080
更新日期:1999-01-01 00:00:00
abstract:AIM:This study aimed to clarify the genetic and epigenetic features of recurrent hydatidiform mole (RHM) in Japanese patients. METHODS:Four Japanese isolated RHM cases were analyzed using whole-exome sequencing. Villi from RHMs were collected by laser microdissection for genotyping and DNA methylation assay of differe...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000441780
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:To determine whether genetic alterations in the CD9 gene are associated with female infertility in humans. METHODS:We sequenced the entire coding region of this gene in 86 Japanese women with unexplained infertility and further conducted a case-control study of six tagging single nucleotide polymorphis...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000262451
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate maternal serum transformed alpha-fetoprotein (MSt-AFP) levels, a new molecular conformation of AFP was used in cases of threatened preterm labor (TPL). METHODS:Prospective case-control study. Maternal serum levels of classical AFP and transformed AFP (t-AFP) were compared between 2 groups m...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000233239
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the influence on fertility and pregnancy outcome in cervical intraepithelial neoplasia (CIN) patients after a loop electrosurgical excision procedure (LEEP) or cold-knife conization (CKC). METHODS:269 patients with CIN-II-III who wanted to conceive were prospectively ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,随机对照试验
doi:10.1159/000360538
更新日期:2014-01-01 00:00:00
abstract::Therapeutic abortion by vacuum aspiration in the first trimester was carried out on 129 healthy multigravid women. The loss of haemoglobin at operation was estimated and the volume of blood calculated. The figures were compared to those in a group of primigravid women earlier reported. Blood loss increases with gestat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000300997
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Radiation therapy is a mainstay in the treatment of cervical cancer. However, most advanced and metastatic cervical cancers are resistant to radiation therapy because of the presence of cancer stem cells (CSCs). To date, no specific markers were found for cervical CSCs. METHODS:The fraction of CD44+/CD24+ c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000493129
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:This study is aimed at comparing the early diagnostic accuracy of maternal blood white blood cell (WBC) count, C-reactive protein (CRP) and procalcitonin in predicting early onset neonatal sepsis (EONS) among early preterm premature rupture of membrane (PPROM) pregnancies. METHODS:A total of 57 consecutive ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000446949
更新日期:2017-01-01 00:00:00
abstract::By means of bacteriological, histological and immunofluorescence methods, the ascending spread of endocervically inoculated bacteria was studied in 14 pregnant sheep. 8 ewes near term were exposed to group B streptococci, Bacteroides fragilis or Streptococcus intermedius for 2-4 days. 6 other animals in mid pregnancy ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299415
更新日期:1983-01-01 00:00:00
abstract::Acupuncture treatment in the final weeks of pregnancy has been claimed to shorten the duration of labor in primiparous women. In the present study, the length of the various phases of labor was calculated for 56 primiparous women who were repeatedly treated with manual acupuncture during the month prior to parturition...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298806
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the antenatal screening of aberrant umbilical vessels and assess the association of fetal abnormality with these entities. STUDY DESIGN:444 pregnant women were studied with routine obstetric ultrasound and Doppler color flow imaging in late second trimester or early third trimester. Fetal growth ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291863
更新日期:1997-01-01 00:00:00