Use of chlorhexidine-releasing nylon fibres to reduce device-related uterine infections.

Abstract:

:Implantation of intrauterine devices (IUDs) is associated with an increased incidence of uterine infection, probably as a result of vaginal bacteria entering the uterus at the time of insertion. To reduce the incidence of IUD-related infections, the incorporation of antimicrobial agents into the tail of the device was studied. Chlorhexidine was shown to be released from within nylon hollow fibres at a rate of approximately 114 microg x day(-1) for 10 days. This rate of release was sufficient to exhibit a biocidal effect on bacteria embedded within a mucus gel in vitro. When these devices were implanted transcervically into the guinea-pig uterus they significantly reduced the extent of uterine bacterial contamination within 24 h. These findings indicate that chlorhexidine-releasing devices are potentially useful in the reduction of device-related infections.

journal_name

Gynecol Obstet Invest

authors

Gard PR,Reynolds JP,Hanlon GW

doi

10.1159/000010256

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

261-5

issue

4

eissn

0378-7346

issn

1423-002X

pii

10256

journal_volume

49

pub_type

杂志文章
  • Relationship between metabolic syndrome and uterine leiomyomas: a case-control study.

    abstract:BACKGROUND/AIMS:Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and well-being. The pathophysiology and epidemiology of fibroids are poorly understood. Obesity and elevated blood pressure have been reported to be predisposing factors. In this study, we investigat...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000114250

    authors: Takeda T,Sakata M,Isobe A,Miyake A,Nishimoto F,Ota Y,Kamiura S,Kimura T

    更新日期:2008-01-01 00:00:00

  • Obstetric outcome in women with endometriosis--a matched case-control study.

    abstract:BACKGROUND:Immunological deficiencies, altered angiogenic activity, infiltrative potential and growth factors are plausible factors behind endometriosis. The aim of this study was to determine whether endometriosis interferes with the course or outcome of pregnancy. STUDY DESIGN:In this matched case-control study, we ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000074815

    authors: Kortelahti M,Anttila MA,Hippeläinen MI,Heinonen ST

    更新日期:2003-01-01 00:00:00

  • Expression of the Peptidase "Fibroblast Activation Protein" on Decidual Stromal Cells Facilitating Tissue Remodeling.

    abstract:INTRODUCTION:Expression of fibroblast activation protein (FAP) has been detected in activated fibroblasts participating in injury response, fibrotic and inflammatory conditions, and tumorigenesis. Human endometrium is equally characterized by rapid tissue remodeling events due to the reproductive tasks comprising the a...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000511439

    authors: Segerer SE,Bartmann C,Schwab M,Kämmerer U

    更新日期:2020-01-01 00:00:00

  • Effect of membrane sweeping at term pregnancy on duration of pregnancy and labor induction: a randomized trial.

    abstract:AIM:To evaluate the efficacy of sweeping of fetal membranes for induction of labor in uncomplicated term pregnancies. METHODS:A randomized controlled trial was performed in 122 pregnant women beyond 39 weeks of gestation with no complications. The women were assigned to have their membranes swept or not (controls) for...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000091842

    authors: Kashanian M,Akbarian A,Baradaran H,Samiee MM

    更新日期:2006-01-01 00:00:00

  • Birth-weight-specific perinatal mortality in Japan, 1989-1993: singleton versus multifetal pregnancies.

    abstract:OBJECTIVE:To investigate the relation between birth weight and perinatal mortality in multifetal pregnancies, which is more than 5 times higher than for singleton infants. METHODS:We assessed the incidence of perinatal deaths based on birth weight in 89,566 infants of multifetal pregnancies and 6,025,199 infants of si...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010131

    authors: Minakami H,Sato I

    更新日期:1999-01-01 00:00:00

  • Pregnancy rate after homologous insemination of pathological ejaculate both with and without the addition of kallikrein.

    abstract::As part of a gynecological-andrological cooperation programme for the treatment of infertile marriages made by the 1st Department of Obstetrics and Gynecology and the Department of Urology, University of Vienna Medical School, the pregnancy rates achieved through 1,269 homologous inseminations of pathological ejaculat...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299429

    authors: Maier U,Grünberger W,Binstorfer E,Lunglmayr G

    更新日期:1983-01-01 00:00:00

  • Elevated immunoreactivity against class I histone deacetylases in adenomyosis.

    abstract:BACKGROUND/AIMS:Adenomyosis is a common condition with a poorly understood pathogenesis. Recent data suggest that it may be an epigenetic disease. This study investigated the expression and localization of class I histone deacetylases (HDACs) in women with and without adenomyosis. METHODS:The ectopic and homologous eu...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000336409

    authors: Liu X,Nie J,Guo SW

    更新日期:2012-01-01 00:00:00

  • A complete pathological response to treatment in a young patient with locally advanced minimal deviation adenocarcinoma of the uterine cervix undergoing chemoradiation followed by radical surgery.

    abstract::Minimal deviation adenocarcinoma (MDA) is a very rare variant of cervical adenocarcinoma, this pathological entity is composed of mucinous very-well-differentiated glands deeply invading cervical stroma, and often surrounded by a desmoplastic reaction. Despite its benign histological appearance, MDA is typically chara...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000327938

    authors: Ferrandina G,Carbone A,Macchia G,Petrillo M,Lucidi A,Morganti AG

    更新日期:2011-01-01 00:00:00

  • Mode of delivery influences the regression of abnormal cervical cytology.

    abstract:AIMS:The purpose was to investigate the influence of delivery mode on the postpartum regression of abnormal cervical cytology. METHODS:A retrospective review was conducted of 64 pregnant women with abnormal cervical cytology at Yonsei University Health System in Korea between 2001 and 2008. A Papanicolaou smear and pa...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000324500

    authors: Chung SM,Son GH,Nam EJ,Kim YH,Kim YT,Park YW,Kwon JY

    更新日期:2011-01-01 00:00:00

  • The special programme of research in human reproduction: forty years of activities to achieve reproductive health for all.

    abstract::The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of e...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 历史文章,杂志文章,评审

    doi:10.1159/000343067

    authors: Benagiano G,d'Arcangues C,Harris Requejo J,Schafer A,Say L,Merialdi M

    更新日期:2012-01-01 00:00:00

  • Scanning electron microscopy of human Fallopian tube in ectopic pregnancy.

    abstract::The scanning electron microscopy by virtue of its high resolution topographic reproduction of epithelial surfaces lining the female genital tract, provides unique information toward understanding the anatomy and physiology of the female reproductive system. The human Fallopian ectopic pregnancy is an urgent gynecologi...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299226

    authors: Samberg I,Degani S,Zilberman A,Eibschitz I,Nir I,Scharf M

    更新日期:1983-01-01 00:00:00

  • The Endometriosis Fertility Index Is Useful for Predicting the Ability to Conceive without Assisted Reproductive Technology Treatment after Laparoscopic Surgery, Regardless of Endometriosis.

    abstract:OBJECTIVE:The endometriosis fertility index (EFI) is a novel index for predicting pregnancy after surgery. We investigated the utility of the EFI for predicting the ability to conceive without assisted reproductive technology (ART) treatment after laparoscopic surgery. METHODS:From July 2011 through December 2012, we ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000480454

    authors: Hobo R,Nakagawa K,Usui C,Sugiyama R,Ino N,Motoyama H,Kuribayashi Y,Inoue M,Sugiyama R

    更新日期:2018-01-01 00:00:00

  • Oestrogen and progesterone receptors in normal human endometrium: comparison of immunocytochemical analysis on frozen and paraffin sections with or without enzymatic pretreatment.

    abstract::Immunocytochemical study in paraffin sections of human endometrium showed that the receptor contents for both oestrogen and progesterone receptors were lower than in the frozen sections although the staining patterns were similar in these two section types. Pretreating the specimens with proteolytic enzymes like tryps...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292422

    authors: Fung HY,Wong YL,Wong FW,Rogers MS

    更新日期:1995-01-01 00:00:00

  • Transient bilateral osteoporosis of the hip in pregnancy. A case report and review of the literature.

    abstract::Osteoporosis of the hip is a rare complication of pregnancy, the diagnosis of which can only be determined by radiologic means. Differentiation between osteonecrosis and osteoporosis remains problematic in some cases. Magnetic resonance imaging was reported as useful for the diagnosis of osteoporosis. Treatment of ost...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000052910

    authors: Axt-Fliedner R,Schneider G,Seil R,Friedrich M,Mink D,Schmidt W

    更新日期:2001-01-01 00:00:00

  • Effect of danazol and ovariectomy on matrix metalloproteinases in rat uteri.

    abstract::The experiments described in this report were designed to study the effects of danazol on matrix metalloproteinases in the rat uterus. Proteinases were analyzed by zymography in gels copolymerized with either gelatin or transferrin. There were no apparent effects of danazol on proteinases from rat uteri when analyzed ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000010218

    authors: Willingham AK

    更新日期:2000-01-01 00:00:00

  • Studies on mitogen-induced lymphocyte transformation and the effect of pregnancy serum on mitogen-induced normal lymphocyte culture.

    abstract::It is recognised that there is a non-reactive status in the maternal immune system during normal pregnancy as it fails to recognise the fetus which is an allograft. The present study was aimed to understand the nature of cell-mediated immune response and the presence of immunosuppressive factors during human pregnancy...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000294838

    authors: Saleem MA,Jha P,Buckshee K,Farooq A

    更新日期:1992-01-01 00:00:00

  • Ovarian morphology in patients with polycystic ovaries and in an age-matched reference material. A statistical evaluation of 149 cases.

    abstract::The ovarian morphology in 149 patients with the clinical syndrome of polycystic ovaries (group I) is described. The ovaries from 10 age-matched women (group II) with no signs of ovarian disorder were investigated as a reference material. The number of cysts documented for group I was twice that of the reference group ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293771

    authors: Lunde O,Hoel PS,Sandvik L

    更新日期:1988-01-01 00:00:00

  • Endometrial adenocarcinoma in early pregnancy.

    abstract::Adenocarcinoma of the endometrium with intrauterine pregnancy is extremely rare. We report the case of a 35-year-old woman with endometrial cancer discovered in the 7th gestational week. A therapeutic abortion was performed and because of bleeding and spotting dilatation and curettage was done 10 days later. Histology...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292043

    authors: Kovács AG,Cserni G

    更新日期:1996-01-01 00:00:00

  • Higher implantation rate using modified quarter laser-assisted zona thinning in repeated implantation failure.

    abstract:BACKGROUND/AIMS:Some embryo implantation problems in patients with recurrent implantation failure may be explained by the inability of the embryo to hatch out of its zona pellucida. In this case-control study, a study group which had received modified quarter laser-assisted zona thinning (mQLAZT) was compared with a co...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000171068

    authors: Debrock S,Spiessens C,Peeraer K,De Loecker P,Willemen D,D'Hooghe TM

    更新日期:2009-01-01 00:00:00

  • Calcium dobesilate lowers the blood pressure in mild to moderate midtrimester hypertension: a pilot study.

    abstract::To test the effects of calcium dobesilate (Doxium) in pregnancies complicated with pregnancy-induced hypertension or mild/moderate pre-eclampsia a double-blind, placebo-controlled pilot study was carried out. Primigravida patients (gestational age

    journal_title:Gynecologic and obstetric investigation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000010080

    authors: Tamás P,Csermely T,Ertl T,Vizer M,Szabó I,Prievara FT

    更新日期:1999-01-01 00:00:00

  • Perinatal environment and endometriosis.

    abstract:BACKGROUND/AIMS:Perinatal environmental exposure may affect fetal development and reprogram the developing organism for adult-onset disease. In this case-control study, we aimed at assessing this pathogenetic model in endometriosis. METHODS:Consecutive patients with a first laparoscopic diagnosis of endometriosis were...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000323531

    authors: Somigliana E,Vigano P,Abbiati A,Paffoni A,Benaglia L,Vercellini P,Fedele L

    更新日期:2011-01-01 00:00:00

  • Effect of LHRH and its analogues on the progesterone secretion of human granulosa cells in vitro.

    abstract::Progesterone secretion of cultured human granulosa cells treated with LHRH or its analogues was measured. Granulosa cells were also stimulated with LH, FSH, cAMP or forskolin. No differences could be observed in the progesterone basal secretion of cultures treated with or without LHRH or its analogues and after the va...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292765

    authors: Török A,Hamori M,Bódis J,Cledon P,Tinneberg HR,Hanf V

    更新日期:1992-01-01 00:00:00

  • Estrogen - and gestagen - receptors in ovarian carcinoma.

    abstract::Estrogen (ER) - and progestagen (PgR) - receptors were estimated by a DCC method using Scatchard plot analysis In tissue samples of 68 patients with ovarian carcinomas. The mean ER and PgR levels were at 52 and 74 fmol/mg cytosol protein, respectively. ER+ PgR+ records were noted in 32.4%, ER+ PgR- in 26.4%, ER- PgR+ ...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299256

    authors: Spona J,Gitsch E,Salzer H,Karrer K

    更新日期:1983-01-01 00:00:00

  • A rabbit model of endometriosis.

    abstract::Since not all problems in endometriosis can be studied in the human, there is need of an animal model. We transplanted endometrial tissue of the rabbit into the peritoneal cavity and studied the changes after 12 weeks. At that time the endometrial implants in the rabbit had become cystic structures. The macroscopic an...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000293611

    authors: Dunselman GA,Willebrand D,Land JA,Bouckaert PX,Evers JL

    更新日期:1989-01-01 00:00:00

  • Hydranencephaly with renal dysgenesis: a coincidental finding? Case report with review of the literature.

    abstract::We present the case of a female fetus aborted in the 20th week of gestation due to severely dysplastic kidneys, anhydramnios and hydranencephalus. The combination of these malformations is extremely rare, resulting in only 4 cases described so far. Our case is the first ever presented in a female showing polycystic-dy...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,评审

    doi:10.1159/000291522

    authors: Gschwendtner A,Mairinger T,Soelder E,Alge A,Kreczy A

    更新日期:1997-01-01 00:00:00

  • Effectiveness and Adverse Events of Early Laparoscopic Therapy versus Conservative Treatment for Tubo-Ovarian or Pelvic Abscess: A Single-Center Retrospective Cohort Study.

    abstract:BACKGROUND/AIM:We aimed to assess the value of early laparoscopic therapy in management of tubo-ovarian abscess (TOA) or pelvic abscess. METHODS:This was a retrospective study of all consecutive patients who were initially diagnosed with TOA or pelvic abscess at the local hospital between January 2010 and December 201...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000493855

    authors: Chu L,Ma H,Liang J,Li L,Shen A,Wang J,Li H,Tong X

    更新日期:2019-01-01 00:00:00

  • Laparoendoscopic single-site surgery for benign ovarian cystectomies.

    abstract:BACKGROUND:Single-port laparoscopy (LESS) utilizes a single, multichannel port in an attempt to decrease postoperative pain, while enhancing cosmesis and minimizing the potential risks and morbidities associated with the multiple ports used in conventional laparoscopy. METHODS:We performed a retrospective study examin...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000367659

    authors: Bedaiwy MA,Sheyn D,Eghdami L,Abdelhafez FF,Volsky JG,Fader AN,Escobar PF

    更新日期:2015-01-01 00:00:00

  • Common genetic changes between endometriosis and ovarian cancer.

    abstract::We analyzed 81 ovarian cancers for loss of heterozygosity (LOH) on 10q23 and for mutations in PTEN. LOH was common among the endometrioid (43%) and serous (28%) cancers, but was infrequent among the other histological subtypes. Somatic PTEN mutations were detected in seven (21%) endometrioid cancers and the mutation i...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章,评审

    doi:10.1159/000052877

    authors: Obata K,Hoshiai H

    更新日期:2000-01-01 00:00:00

  • Ultrastructure of rabbit endosalpinx and glycoprotein pattern of the oviduct fluid in the presence of copper intrauterine devices.

    abstract::Oviduct fluid was collected from 24 mature female rabbits in estrus fitted with a copper intrauterine device (IUD) in one of the uterine horns by laparotomy and examined for total sugar and protein content. The percentage of total sugar in the dry protein-containing material from the experimental side was 7.3 compared...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000299449

    authors: David A,Levinsky H,Malik Z,Langzam Y,Feller N,Shaked P,Allalouf D

    更新日期:1982-01-01 00:00:00

  • Plasma prealbumin in women with epithelial ovarian carcinoma.

    abstract:BACKGROUND:Epithelial ovarian carcinoma produces steroid hormones that may be of prognostic importance. The steroids are mainly bound to plasma albumin and sex hormone-binding globulin. Alterations in plasma protein levels influence hormonal effects. As plasma prealbumin may reflect changes in the patient's clinical st...

    journal_title:Gynecologic and obstetric investigation

    pub_type: 杂志文章

    doi:10.1159/000292542

    authors: Mählck CG,Grankvist K

    更新日期:1994-01-01 00:00:00