Abstract：
:The ontogeny of Ia antigen expression on cells within the decidua basalis of the placenta and on decidual cells differentiating in vitro was investigated in the mouse. The results indicate that Ia antigen expression is temporarily restricted and can be detected in short-term cultures of decidual tissue only during the final third of gestation. The Ia antigen positive cells, which are non-phagocytic, non-specific esterase negative and lack Fc receptors, appear to be true decidual cells on the basis of their fine structural characteristics. In contrast, morphologically identical dendritic decidual cells arising from differentiation in vitro of endometrial cells do not express Ia antigens. A population of small rounded cells was also present in cultures of both decidual tissue and in vitro decidualized endometrial cells. These rounded cells possess the macrophage-like properties of Fc receptors, non-specific esterase and phagocytic activity. The possible function of these cell populations within the decidual tissue is discussed.
journal_name
Placentajournal_title
Placentaauthors
Searle RF,Bell SC,Billington WDdoi
10.1016/s0143-4004(83)80027-7subject
Has Abstractpub_date
1983-04-01 00:00:00pages
139-48issue
2eissn
0143-4004issn
1532-3102pii
S0143-4004(83)80027-7journal_volume
4pub_type
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