Abstract：
:A role for Substance P (SP) in human placenta is not known, although is possible that regulates placental physiology through the Neurokinin (NK)-1 receptor. Ten human normal placenta tissues were studied by immunohistochemistry to demonstrate the localization of NK-1 receptor and SP. An immunostaining pattern for NK-1 receptor and SP was observed in the endothelium and myocytes of fetal blood vessels, decidua and trophoblast. The SP is located in both the cytoplasm and the nucleus whereas NK-1 receptor in cytoplasmic. These findings reported here for the fist time, suggest a role for the SP and NK-1 receptor in the placental physiology.
journal_name
Placentajournal_title
Placentaauthors
Muñoz M,Pavón A,Rosso M,Salinas MV,Pérez A,Carranza A,González-Ortega Adoi
10.1016/j.placenta.2010.03.015subject
Has Abstractpub_date
2010-07-01 00:00:00pages
649-51issue
7eissn
0143-4004issn
1532-3102pii
S0143-4004(10)00138-4journal_volume
31pub_type
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