Abstract：
:Two groups of placentae from 18 cases of maternal rubella were examined morphologically and virologically. Placentae in Group I (four cases) had a mean gestational age of 21 +/- 1.9 weeks, whilst those in Group 2 (14 cases) had a mean gestational age of 38 +/- 2.8 weeks. A tendency to hypoplasia was observed. The microscopic lesions were similar to those found in other viral infections but in each group some specific features were noted. Only placentae of Group I showed nodules of villi agglutinated by fibrin. This lesion suggested recent maternal infection. Attention is drawn to the presence of abnormal areas of lobular rarefaction due to dysmaturity of villous stem and terminal villi. This aspect was more diffuse and accentuated in Group 2 placentae. Villitis of reactive, necrotic, proliferative and reparative types was seen only in placentae of Group 2. Devastating villitis was not observed. Inclusions in placental cells suggested rubella infection. The lesions were non-specific and hence stress the need for virological examination of the placenta, immunofluorescence studies and electron microscopy to confirm the diagnosis.
journal_name
Placentajournal_title
Placentaauthors
Garcia AG,Marques RL,Lobato YY,Fonseca ME,Wigg MDdoi
10.1016/s0143-4004(85)80038-2subject
Has Abstractpub_date
1985-07-01 00:00:00pages
281-95issue
4eissn
0143-4004issn
1532-3102pii
S0143-4004(85)80038-2journal_volume
6pub_type
杂志文章相关文献
PLACENTA文献大全abstract：INTRODUCTION:The decidual reaction and the formation of new vessels in the uterus are two crucial processes during embryo implantation. Previously, we observed that lysophosphatidic acid (LPA) increases cyclooxygenase-2 derived - prostaglandin E2 production during implantation in the rat uterus and that it augments the...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2013.06.001
更新日期：2013-09-01 00:00:00
abstract：:In view of the pathological placental features of pre-eclampsia and intrauterine growth restriction (IUGR), and the angiogenic effects of vascular endothelial growth factor (VEGF), the aim of this study was to determine the expression of VEGF in placentae from normal pregnancies and to compare the results with placent...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/s0143-4004(97)80061-6
更新日期：1997-05-01 00:00:00
abstract：:The aim of the present study was to evaluate the relationship between the retention of fetal membranes (RFM) and apoptosis of the cells in fetal membranes. The present study investigated mRNA and protein expressions of apoptosis-regulating factors: FAS, cellular FLICE-like inhibiting protein (cFLIP), BAX, BCL2, caspas...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2010.10.016
更新日期：2011-01-01 00:00:00
abstract：:Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity. There is no treatment currently available for FGR. Its primary cause, when not attributable...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2015.03.003
更新日期：2015-06-01 00:00:00
abstract：:The expression pattern of MHC class I genes in trophoblast cells at the feto-maternal interface is thought to be the basis of the maintenance of pregnancy by protecting the fetus from maternal immune rejection. Transcription of classical HLA class I genes is low or undetectable in most trophoblast cells as well as in ...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1053/plac.1998.0380
更新日期：1999-05-01 00:00:00
abstract：:Mitochondrial function is required to support energetically-demanding processes in the placenta. As such, a compromise in mitochondrial function could severely impact fetal growth and development. Respirometry is a highly useful method for studying mitochondrial function, but is not possible in freeze-thawed mitochond...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2011.11.019
更新日期：2012-02-01 00:00:00
abstract：UNLABELLED:Placental hypoxia has been implicated in pregnancy pathologies such as preeclampsia. We have previously reported that AQP9 is highly expressed in syncytiotrophoblast from normal placentas and shows an overexpression in preeclamptic placentas, with a lack of functionality for water transport. Up to now, the r...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2013.04.017
更新日期：2013-08-01 00:00:00
abstract：:We present a case of intra-amniotic umbilical vein varix with thrombosis using conventional two-dimensional (2D) sonography, power Doppler, three-dimensional (3D) HD-flow, and HDlive at 35 weeks of gestation. 2D sonography showed a large banana-like umbilical cord enlargement (100 × 43.3 × 45.9 mm) including umbilical...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2013.08.008
更新日期：2013-11-01 00:00:00
abstract：:The fetus has a substantial demand for glycine, which is satisfied in part by placental formation. The ability to form glycine through the activity of alanine:glyoxylate aminotransferase enzyme was measured in placentae from normal term human pregnancies and placentae from rats at day 20 of gestation. There was no det...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/s0143-4004(98)90066-2
更新日期：1998-05-01 00:00:00
abstract：:The keratin cytoskeleton is present in all trophoblast cell subtypes of the mouse and human placenta and is required to maintain the structural integrity of these cells. Recently, various genetic mouse models have shown that a normal keratin network is necessary for placental development. Keratin-deficiency leads to t...
journal_title：Placenta
pub_type：
doi：10.1016/j.placenta.2007.01.006
更新日期：2007-04-01 00:00:00
abstract：:We developed a model of maternal hyperglycaemia with secondary hyperinsulinaemia and hypoaminoacidaemia in pregnant sheep (H) to determine the effect of these conditions on uterine, uteroplacental and fetal amino-acid uptake rates and fetal amino-acid concentrations [AA]. Results were compared with normal pregnant ewe...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1053/plac.2000.0610
更新日期：2001-02-01 00:00:00
abstract：:Embryo implantation is the group of processes by which the developing blastocyst adheres to, and embeds into, the receptive endometrium. Changes in the expression of molecules on the cell surface have been seen in the conversion of the endometrial surface from a non-receptive to a receptive state. Cell adhesion molecu...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2010.10.002
更新日期：2010-12-01 00:00:00
abstract：:Combined staining of non-cultured interphase nuclei from hydatidiform moles with distamycin A and DAPI resulted in the presence of specific stained interphase bodies. A mean number of six interphase bodies was observed in moles with a diploid karyotype and a mean number of nine interphase bodies was observed in triplo...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/s0143-4004(85)80046-1
更新日期：1985-07-01 00:00:00
abstract：:Second trimester maternal serum human chorionic gonadotrophin (hCG) levels in women who remained normotensive but delivered an unexplained growth retarded infant were compared with those from a control group and a group of women who developed pre-eclampsia in a retrospective observational study. Our hypothesis was tha...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/s0143-4004(98)90002-9
更新日期：1998-03-01 00:00:00
abstract：:Bidirectional transplacental exchange characterizes human pregnancy. Cells exchanged between mother and fetus can durably persist as microchimerism and may have both short- and long-term consequences for the recipient. The amount, type, and persistence of microchimerism are influenced by obstetric characteristics, pre...
journal_title：Placenta
pub_type： 杂志文章,评审
doi：10.1016/j.placenta.2017.08.071
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:The objective of this study was to explore serum levels of differentially abundant proteins between women with hypertensive disorders of pregnancy (HDP) and women with normal-term pregnancy, and to explore the contribution of SH3BGRL3 to the pathogenesis of HDP. METHODS:At 6-20 weeks gestation 48 pregnant...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2020.10.031
更新日期：2020-11-14 00:00:00
abstract：INTRODUCTION:Miscarriage is the most common placental-related complication of pregnancy. It has been extensively investigated to discover the underlying mechanism(s) by which miscarriage occurs, but in many cases the etiology still remains unclear. The aim of this study was to analyze genome-wide expression profiles of...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2012.12.003
更新日期：2013-02-01 00:00:00
abstract：:Fetoplacental blood vessel constriction in response to reduced oxygenation has been demonstrated in placenta perfused in vitro. In pulmonary vessels, hypoxic vasoconstriction involves Ca2+ influx into smooth muscle through membrane ion channels including voltage-gated Ca2+ channels (VGCCs). We hypothesised that VGCCs ...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2005.04.012
更新日期：2006-04-01 00:00:00
abstract：:Interleukin (IL)-17 is a proinflammatory cytokine with pleiotropic activities including inducing neovascularization and production of proangiogenic molecules. As pregnancy outcome depends on the balance of Th1-like/Th2-like cytokines and an increased blood supply to the fetoplacental unit, the expression of IL-17 mRNA...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2006.01.016
更新日期：2007-01-01 00:00:00
abstract：:Growth characteristics and the expression of trophoblast-associated markers by six cell lines generated from midgestation chorioallantoic placentas of outbred (Holtzman) and inbred (Lewis, PVG.RT Ir8) rats were evaluated. The cells comprising all cell lines were epithelioid (contained cytokeratin-type intermediate fil...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/0143-4004(89)90038-6
更新日期：1989-03-01 00:00:00
abstract：:Early placental development is characterised by rapid cell differentiation and migration, matrix remodelling and angiogenesis. The enzyme NAD(P)H oxidase is a major source of superoxide anions implicated in signalling pathways regulating these processes in other systems. It is also thought to be involved in oxygen sen...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2005.02.013
更新日期：2006-02-01 00:00:00
abstract：:Decidualization process involves the morphological and functional transformation of endometrial stromal cells into decidual cells. This is a finely regulated process, which involves proliferation and differentiation of stromal cells into decidual cells, which is followed by regression of the decidual tissue, mainly by...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2011.03.007
更新日期：2011-06-01 00:00:00
abstract：:The ability to directly monitor the status of the placenta throughout pregnancy would be a major advance in both general and personalized obstetric care, allowing treatments to be tailored to the dynamic changes that can occur in gestation. Syncytiotrophoblast extracellular vesicles (STBEV) are membrane bound vesicles...
journal_title：Placenta
pub_type： 杂志文章,评审
doi：10.1016/j.placenta.2016.11.008
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:Increasing evidence suggests an association between periodontal disease and low birthweight (LBW); however the underlying molecular mechanisms are yet to be fully elucidated. In this study, we performed a microarray analysis to observe the human placental trophoblast-like BeWo cells response to lipopolysaccha...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2010.10.007
更新日期：2011-01-01 00:00:00
abstract：:The human placenta is capable of producing a variety of haematopoietic growth factors in vitro. It is not clear, however, whether the placenta produces such factors in vivo and if so, whether placental production of haematopoietic growth factors has a physiological role in fetal haematopoietic development. As a step t...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/s0143-4004(96)80079-8
更新日期：1996-11-01 00:00:00
abstract：:Gestational diabetes mellitus is a common medical complication in pregnancy. Recent findings demonstrate that glyburide is effluxed against a concentration gradient from the fetal to the maternal circulation. However, the transport systems involved in the active efflux of glyburide in the human placenta have not yet b...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2008.05.001
更新日期：2008-08-01 00:00:00
abstract：:Parathyroid hormone-related protein (PTHrP), the major factor responsible for hypercalcaemia of malignancy, is widely expressed in normal adult and fetal tissues. In this study, the distribution of PTHrP was examined in human term placenta and membranes by immunohistochemistry using antisera to PTHrP 1-34 and 37-67. P...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/s0143-4004(05)80411-4
更新日期：1994-09-01 00:00:00
abstract：OBJECTIVES:Histiotrophe is now recognized as being an important feature of early human pregnancy, providing nutrients and growth factors to the developing embryo. Our aim was to examine the glycan composition of histiotrophe from first trimester decidua and to compare it with secretions present in endometrial glands fr...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2010.04.011
更新日期：2010-07-01 00:00:00
abstract：:Umbilical cord blood is an important graft source in the treatment of many genetic, hematologic, and immunologic disorders by hematopoietic stem cell transplantation. Millions of cord blood units have been collected and stored for clinical use since the inception of cord blood banking in 1989. However, the use of cord...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1016/j.placenta.2020.10.018
更新日期：2020-10-13 00:00:00
abstract：:To clarify the biological and pathological features of choriocarcinoma, we evaluated the in vitro production of cytokines by a choriocarcinoma cell line, BeWo. We measured the concentration of interleukin (IL)-6 and IL-8 in the culture media of BeWo cells after stimulation with various modulatory agents of cytokine ex...
journal_title：Placenta
pub_type： 杂志文章
doi：10.1053/plac.1999.0494
更新日期：2000-05-01 00:00:00
