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Antibody-dependent cellular cytotoxicity in poikilotherms.

Abstract：

:51Cr-chromate labelled chicken red blood cells, treated with rabbit (anti-chicken red blood cell) serum, are lysed in vitro, in the absence of complement, by spleen cells from Xenopus laevis, Ambystoma mexicanum or Lacerta viridis. Optimal conditions for lysis by Xenopus spleen cells were determined. The phenomenon seems homologous with antibody-dependent cellular cytotoxicity (ADCC) mediated by mammalian or avian K cells. The phylogenetic significance of the finding is discussed.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Jurd RD,Doritis A

doi

10.1016/s0145-305x(77)80017-7

subject

Has Abstract

pub_date

1977-10-01 00:00:00

pages

341-52

issue

4

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(77)80017-7

journal_volume

1

pub_type

杂志文章

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