Abstract:
:Six cases of dermatofibrosarcoma protuberans were studied ultrastructurally. Biopsy material from all six cases as well as cell cultures derived from four cases were examined. In all cases, the tumor cells in vivo and in vitro were related to fibroblasts. The two cases with histiocytoid features and a small spiral pattern exhibited numerous lipid vacuoles but no histiocytic cell markers. In these two cases, cultured cells contained a higher number of intracytoplasmic vacuoles than the control fibroblasts. Two other cases exhibited some basement-membrane-like material surrounding tumor cells. All of the investigated cell strains obtained from the tumors showed synthesis of collagenous proteins similar to that found in fibroblasts. However, the level of total collagen was reduced, and type-III collagen was absent. The morphological variations in these cases of dermatofibrosarcoma protuberans appeared to be related to the histological pattern and may reflect the heterogeneity of normal fibroblasts.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Schmoeckel C,Albini A,Krieg T,Stets Rdoi
10.1007/BF00409221subject
Has Abstractpub_date
1985-01-01 00:00:00pages
138-47issue
2eissn
0340-3696issn
1432-069Xjournal_volume
278pub_type
杂志文章abstract::The adenylate cyclase system of an established human trichilemmoma cell line was investigated. Stimulators of human epidermal adenylate cyclase system, epinephrine, histamine, adenosine, and prostaglandin E increased cyclic AMP levels of the trichilemmoma cells. The effects of epinephrine, histamine, and adenosine wer...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00413285
更新日期:1987-01-01 00:00:00
abstract::Two male patients with longstanding contact sensitivity to chromium were treated with PUVA. One patient, suffering from concomitant photosensitivity, reacted very favorably; his skin lesions cleared and light tolerance increased. This was paralleled by a decrease in the photopatch test reactivity and by the extinction...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00403929
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abstract::Scleroderma is a heterogeneous disease with a complex etiology. As more information is gained about the underlying mechanisms and the improved classifications of scleroderma subtypes, treatments can be better personalized. Improving scleroderma patients' early diagnosis before end organ manifestations occur should imp...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1257-x
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journal_title:Archives of dermatological research
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doi:10.1007/s00403-014-1471-9
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journal_title:Archives of dermatological research
pub_type: 杂志文章
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050202
更新日期:1997-05-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372134
更新日期:1993-01-01 00:00:00
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journal_title:Archives of dermatological research
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00694624
更新日期:1979-10-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371573
更新日期:1994-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00516548
更新日期:1983-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00505639
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00424276
更新日期:1989-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00569101
更新日期:1980-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00409248
更新日期:1982-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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更新日期:2006-06-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1291-8
更新日期:2012-11-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1530-2
更新日期:2015-05-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02507101
更新日期:1996-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00403-015-1579-6
更新日期:2015-10-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00417528
更新日期:1986-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
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更新日期:2018-03-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00455391
更新日期:1978-07-28 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-015-1606-7
更新日期:2016-01-01 00:00:00