Abstract：
:Sequential treatment with clomiphene citrate, human menopausal gonadotropin, and human chorionic gonadotropin was successfully applied to 149 women in the framework of an in vitro fertilization and embryo transfer program and led to the birth of normal children. An average of 3.5 follicles was promoted at each cycle. Oocyte maturity was evaluated at recovery either histologically or with respect to cumulus-oocyte complexes (COC) and correlated to oocyte fertilizability. Three types of COC are described according to cell dissociation and mucification. The most expanded cumulus mass (type I) was highly fertilizable, compared with granular and poorly dissociated cumulus complexes (types II and III, respectively). No improvement in the type II and III oocyte fertilizability was obtained when type I follicular fluid was added to the incubation medium. Moreover, incubation of type III oocytes in medium containing type III follicular fluid seemed to decrease their fertilizability.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Plachot M,Mandelbaum J,Cohen JJ,Debache C,Pigeau F,Junca AMdoi
10.1016/s0015-0282(16)48382-2subject
Has Abstractpub_date
1985-02-01 00:00:00pages
255-62issue
2eissn
0015-0282issn
1556-5653pii
S0015-0282(16)48382-2journal_volume
43pub_type
杂志文章abstract：:We hypothesized that diminished endothelin 1 (ET-1) expression at the spermatic vein wall level might be responsible for the development of varicocele. However, immunohistochemical evaluation of spermatic and control vein samples from 55 patients with varicocele showed overexpression of ET-1 and its receptors ETA and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.04.062
更新日期：2011-06-30 00:00:00
abstract：OBJECTIVE:To compare pregnancy rates (PRs) using blastocysts cryopreserved on day 7 with those cryopreserved on days 5 and 6. DESIGN:Retrospective observational cohort study. SETTING:Infertility center performing IVF. PATIENT(S):Eight hundred women with infertility undergoing frozen ET. INTERVENTION(S):Blastocysts ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.06.021
更新日期：2013-10-01 00:00:00
abstract：:A double-blind randomized study was performed in two groups of eight normally cycling patients: group I received 10 mg/d of RU486 for 4 days from the date of ovulation and group II received a placebo. On day +5, cytosol and endometrial estrogen receptors (ERs), and progesterone receptors (PRs) were analyzed by radioli...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)54183-1
更新日期：1991-03-01 00:00:00
abstract：:A case of intramural but not interstitial pregnancy, established after IVF/ET, is described. The etiologic, diagnostic, and therapeutic aspects of this clinical dilemma are discussed. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54804-3
更新日期：1992-01-01 00:00:00
abstract：:A couple may be considered to have fertility problems if they have been trying to conceive for over 1 year with no success. Worldwide, the inability to have children affects 10% to 15% of all couples. Subfertility can be divided into either male or female factor, or both partners can be affected. However, for some cou...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2018.05.028
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To determine the hormonal characteristics of a fecund menstrual cycle. DESIGN:Prospective observational study. SETTING:Clinical research center. PATIENT(S):Fourteen patients having artificial insemination with donor semen provided daily blood and urine samples in a nonconceptive cycle and the consecutive c...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)01765-9
更新日期：2001-03-01 00:00:00
abstract：:The penetration of a gonadotropin-releasing hormone agonist (GnRH-a), Buserelin (Hoechst AG, Frankfurt, West Germany), into human follicular fluids (FF) was studied by means of a radioimmunoassay (RIA) and a bioassay. Acute nasal administration of a therapeutic dose of Buserelin (300 and 600 micrograms) before the ovu...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60852-x
更新日期：1989-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the interactive effects of dietary soy and menstrual cycle phase on breast proliferation, apoptosis, and sex steroid receptor expression in premenopausal female cynomolgus monkeys. DESIGN:Animals were randomized to receive diets with either casein lactalbumin or soy as the protein source for 12 m...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.08.059
更新日期：2006-04-01 00:00:00
abstract：:Chromosomal abnormalities, sperm DNA damage, zona hardening, inadequate culture conditions, and suboptimal embryo development all play a significant role in the etiology of recurrent implantation failure. Evidence suggests that preimplantation genetic screening does not increase implantation or live birth rates. Compa...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2012.02.029
更新日期：2012-05-01 00:00:00
abstract：:The morphologic characteristics of 85 cryptorchid and 63 contralateral (scrotal) testes showing histologic changes of puberty were studied. Spermatogenesis was not only delayed on the cryptorchid side but also hypocellular in all cases. The scrotal testes appeared hypocellular in 82.5% of the cases. Repetitive biopsie...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)46346-6
更新日期：1982-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the pregnancy and delivery outcome of robot-assisted tubal reanastomosis. DESIGN:Retrospective cohort study. SETTING:University hospital. PATIENT(S):Ninety-seven patients with available follow-up who underwent the reversal of tubal ligation, with a median age of 37 years (range, 24-47 years). ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.10.028
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To determine whether fallopian sperm perfusion significantly improves pregnancy rates over intrauterine insemination (IUI) in infertile patients. DESIGN:Prospective, randomized, controlled trial and metaanalysis of the literature. SETTING:University-based infertility practice. PATIENT(S):Patients undergoin...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,meta分析,随机对照试验
doi：10.1016/s0015-0282(99)00068-0
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To characterize sperm parameters from thawed semen samples of men with different cancers who cryopreserved semen before oncologic therapy. DESIGN:Retrospective cohort study. SETTING:Tertiary academic medical center. PATIENT(S):1,010 semen samples collected between 1994 to 2010. INTERVENTION(S):None. MAIN...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.09.031
更新日期：2013-02-01 00:00:00
abstract：:A detailed study was initiated to investigate thoroughly the possibility that any significant ophthalmologic changes might have occurred in patients using oral contraceptives (OCs) for varying periods. There were 212 patients and 50 control patients who were selected at random, 1/2 from private ophthalmology practice...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)35820-4
更新日期：1966-01-01 00:00:00
abstract：:"To understand the actual world as it is, not as we should wish it to be, is the beginning of wisdom." - Bertrand Russell. ...
journal_title：Fertility and sterility
pub_type： 社论
doi：10.1016/j.fertnstert.2018.06.007
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:Immunobead testing (IBT), the current standard for antisperm antibody detection, is time consuming and somewhat subjective. To overcome these limitations and maintain accuracy, we studied an immunofluorescent assay using flow cytometry. DESIGN:A validation study comparing flow cytometry to IBT in the detecti...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To create a library enriched in cDNAs from preeclamptic placentas to print onto microarrays for placental profiling of preeclampsia (PE) and high risk pregnancies. DESIGN:Prospective study. SETTING:University women's clinic and academic research laboratory. PATIENT(S):Ten patients with PE, 5 with PE and bi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.09.030
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To assess the effect of age and ovarian function on endometrial receptivity. DESIGN:Retrospective comparison between standard IVF and ovum donation in younger and older patients (< 40 and > or = 40 years of age, respectively). PATIENTS:In standard IVF, there were 325 transfer cycles in older patients and 1,...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56104-4
更新日期：1993-08-01 00:00:00
abstract：:Meta-analyses have become an increasingly popular method of drawing conclusions when there are multiple publications addressing a particular topic. While the statistical calculations are straightforward, many of the decisions regarding the research question, populations of interest, and inclusion/exclusion criteria ar...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2011.05.029
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To assess the minimal effective dose of a GnRH antagonist (Cetrorelix; Asta Medical; Frankfurt, Germany) to prevent premature LH surge in patients undergoing controlled ovarian hyperstimulation (COH) for assisted reproductive technologies. DESIGN:In 69 patients COH was carried out with the association of hMG...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81407-0
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To assess the effects of age on the hormonal, metabolic, and ultrasonographic features of polycystic ovary syndrome (PCOS). DESIGN:Observational study. SETTING:University department of obstetrics and gynecology. PATIENT(S):Patients with PCOS (n = 1,212) and healthy women (n = 254). INTERVENTION(S):None. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.11.041
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To investigate the ability of N-formyl-methionyl-leucyl-phenylalanine (f-MLP), complement 5a (C5a), and nerve growth factor (NGF) to stimulate human spermatozoal reactive oxygen species generation in fertile and infertile patients. DESIGN:Prospective, controlled study measuring human spermatozoal reactive ox...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55874-9
更新日期：1993-04-01 00:00:00
abstract：OBJECTIVE:To review recent advances in understanding the role of leptin in the physiology and pathophysiology of reproduction, with a focus on relevant clinical situations. DESIGN:A MEDLINE computer search was performed to identify relevant articles. RESULT(S):Leptin, an adipocyte hormone important in regulating ener...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(01)03010-2
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of growth hormone (GH) supplementation in improving the in vitro fertilization (IVF) outcomes of poor responders. DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENT(S):Poor ovarian responders undergoing conventional IVF or intracytoplasmic sperm inject...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.03.007
更新日期：2020-07-01 00:00:00
abstract：:The effectiveness of Buserelin (Hoechst-Roussel Pharmaceuticals, Inc., Somerville, NJ) (0.2 mg subcutaneously [SC] or 1.2 mg intranasally [IN] per day) and danazol (800 mg per day) in inducing ovarian suppression for the management of endometriosis was compared in a prospective randomized study. During 6 months of tre...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)60543-5
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of vascular endothelial growth factor (VEGF) injection into the testes on spermatogenesis and apoptosis in a varicocele-induced adolescent rat model. SETTING:University hospital urology research laboratory. ANIMAL(S):Six-week-old male Wistar rats (n = 32). INTERVENTION:The rats we...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.06.008
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:To determine a successful method of selecting patients for natural cycle IVF combined with in vitro maturation (IVM) of immature oocytes and to determine treatment efficacy. DESIGN:Retrospective analysis of IVF treatments. SETTING:Hospital IVF clinic. PATIENT(S):Women with infertility according to ovarian ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.01.066
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To assess the risk of cervical neoplasia associated with the use of ovulation-inducing agents such as clomiphene citrate (CC) DESIGN: Case-cohort study. SETTING:Infertility clinics in Seattle, Washington. PATIENTS:A cohort of 3,837 women evaluated for infertility at some time during 1974-1985. MAIN OUTCOME...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Solid-phase enzyme immunoassays, based on monoclonal antibodies reactive with different forms of human placental-type alkaline phosphatases, were applied to their detection in human seminal plasma from fertile and infertile men. The placental-like form of alkaline phosphatase (PLAP-like AP), known to occur in testicul...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
abstract：OBJECTIVE:To investigate whether proteins secreted in urine differ between women with and without endometriosis. DESIGN:Laboratory study using human urine. SETTING:University-based laboratory. PATIENT(S):Women with and without endometriosis undergoing laparoscopy, hysteroscopy and curettage. INTERVENTION(S):Urine c...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.05.016
更新日期：2011-01-01 00:00:00
