Abstract：
:A detailed study was initiated to investigate thoroughly the possibility that any significant ophthalmologic changes might have occurred in patients using oral contraceptives (OCs) for varying periods. There were 212 patients and 50 control patients who were selected at random, 1/2 from private ophthalmology practice and 1/2 from Planned Parenthood Centers in Los Angeles. During eye examinations, the visual acuity and tonometric measurements were recorded. After pupillary dilation, slit-lamp and funduscopic examinations were performed. Among the compounds being taken by patients in this program were norethynodrel-mestranol combinations, norethindrone-mestranol preparations, medroxyprogesterone acetate with ethinyl estradiol, norethindrone acetate-ethinyl estradiol, and norethindrone-mestranol sequential. None of the control patients were using any medication similar to that of the patients under study, and all were given the same examination by the same opthalmologist. A substantial percentage of patients using OCs had some degree of ocular pathology. Much of this was of an insignificant variety and could in no way be related to OC use. In 212 patients (424 eyes) there were 6 instances in which there were potentially progressive lens conditions of unknown cause. None was of the classic complicated or toxic types of cataract. In the small group of control patients, 4% of the eyes had subcapsular vacuoles of the lens. In the contraceptive-treated group, there were only approximately 1.5% showing similar potentially progressive lens pathology. There was 1 case of potential galucoma in the control group and 1 in the contraceptive-treated group. No papilledema was observed in this series.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Faust JM,Tyler ETdoi
10.1016/s0015-0282(16)35820-4subject
Has Abstractpub_date
1966-01-01 00:00:00pages
1-6issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(16)35820-4journal_volume
17pub_type
杂志文章abstract：OBJECTIVE:To determine the effects of low-dose aspirin on ovarian response, uterine and ovarian blood flow velocity, and implantation and pregnancy rates in patients undergoing IVF. DESIGN:Prospective, randomized, double-blind placebo-controlled assay. SETTING:Department of Reproductive Medicine, CER Medical Institut...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(99)00088-6
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To determine the expression of glutathione peroxidase (GPx) in the eutopic and ectopic endometria during the menstrual cycle in endometriosis and adenomyosis. DESIGN:Immunohistochemical identification of GPx in endometrial tissues identified using the polyclonal antibody. SETTING:Department of obstetrics an...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)00638-5
更新日期：2000-08-01 00:00:00
abstract：:Buserelin acetate, a luteinizing hormone-releasing hormone agonist, is known to be effective in the shrinkage of uterine fibroids. A prospective trial was undertaken (1) to compare the efficacy of intranasal (IN) and subcutaneous (SC) administration of buserelin acetate and (2) to assess if tumor regression correlated...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)54001-1
更新日期：1990-12-01 00:00:00
abstract：OBJECTIVE:To examine the relationship between MMPI-2 scores and oocyte donation outcome. DESIGN:Descriptive chart review. SETTING:Two oocyte donation programs. SUBJECT(S):Five hundred anonymous oocyte donor applicants. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Demographics, MMPI-2 scores and donation outcome. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.08.064
更新日期：2010-10-01 00:00:00
abstract：:Two hundred twenty consecutive in vitro fertilization (IVF) conception cycles were studied prospectively in order to examine the predictive value of serum human chorionic gonadotropin beta-subunit (beta-hCG), estradiol (E2), and progesterone (P) in predicting pregnancy outcome between 2 and 4 weeks after oocyte collec...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60495-8
更新日期：1989-02-01 00:00:00
abstract：OBJECTIVE:To determine the role of parental and biological factors on the U.S. male birth fraction from 1964 through 1988. DESIGN:Logistic regression on annual U.S. male births by race group. SETTING:Population-based data. PATIENT(S):Live births in the United States 1964 through 1988. INTERVENTION(S):None. MAIN OU...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00576-2
更新日期：2000-03-01 00:00:00
abstract：:Semen samples from 120 consecutive unselected men attending our fertility clinic were studied to determine the bacterial isolation rate of semen and its influence on semen quality. Each sample was cultured aerobically, anaerobically, and for Ureaplasma urealyticum and Mycoplasma hominis. The following were analyzed fo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)49105-3
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:To correlate the diagnosis of endometriosis in lesions excised at laparoscopy with pathologic diagnosis. DESIGN:Prospective study. SETTING:U.S. government research hospital. PATIENT(S):Women with chronic pelvic pain thought to be due to endometriosis. INTERVENTION(S):Excision of lesions suspicious for end...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03337-x
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:To assess the expression and cellular distribution of pregnancy-associated plasma protein-A (PAPP-A) and major basic protein (MBP) in human ovarian tissue during the menstrual cycle. DESIGN:Ovarian tissues (n = 50) and corpora lutea (n = 18) were obtained from patients undergoing hysterectomy/oophorectomy fo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(03)00077-3
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:To determine whether progestins activate vascular endothelial growth factor (VEGF) gene transcription in endometrial adenocarcinoma cells. DESIGN:In vitro study. SETTING:University reproductive biology laboratories. PATIENT(S):None. INTERVENTION(S):Ishikawa cells were transfected with VEGF promoter-lucife...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)04577-6
更新日期：2003-02-01 00:00:00
abstract：:A battery-powered, bipolar electrocoagulator has been specifically developed for sealing the cut ends of the divided vas at vasectomy. With a minimum of electric power, the electrocoagulator destroys only the mucosa and one or two muscle cell layers of the vas, which leads to optimal fibrosis of the cut ends. This ins...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To describe novel embryo features capable of predicting implantation potential as input data for an artificial neural network (ANN) model. DESIGN:Retrospective cohort study. SETTING:University-affiliated private IVF center. PATIENT(S):This study included 637 patients from the oocyte donation program who un...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.08.023
更新日期：2020-12-01 00:00:00
abstract：:Tamoxifen therapy in premenopausal women with breast cancer may be associated with the development of ovarian cysts. In this report, a case of ovarian torsion associated with TAM therapy is described. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55688-x
更新日期：1993-02-01 00:00:00
abstract：:The current study was formulated to investigate the abortifacient activity of prostaglandin 15-methyl F2alpha (15-methyl PGF2alpha) administered intramuscularly to 80 healthy women with gestations between 8 and 22 weeks. Goals were the establishment of an effective dosage schedule and assessment of the incidence and s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
abstract：OBJECTIVE:To evaluate a new strategy for comprehensive chromosome screening at the blastocyst stage. DESIGN:Clinical research study. SETTING:An IVF clinic and a specialist preimplantation genetic diagnosis laboratory. PATIENT(S):Forty-five infertile couples participated in the study. The mean maternal age was 37.7 y...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.10.015
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To determine the influence of estrogens on male fertility. DESIGN:A 36-year-old eugonadal male was subjected to two different regimens of treatment with ethinyl estradiol (EE2). Sperm quality, immunoreactive luteinizing hormone (LH) and follicle-stimulating Hormone (FSH), testosterone (T), estrone (E1), estr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55271-6
更新日期：1992-09-01 00:00:00
abstract：OBJECTIVE:To investigate for differences in reproductive hormone levels in male relatives of women with polycystic ovary syndrome (PCOS). DESIGN:Cross-sectional study. SETTING:Academic medical center. PATIENT(S):Sixty-three fathers and 66 brothers of women with PCOS as well as two groups of control men of comparable...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.03.029
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:To determine whether obesity affects serum and seminal measures of male reproductive potential among a multi-institutional cohort. DESIGN:Retrospective multi-institutional cohort study. SETTING:Infertility clinics. PATIENT(S):All men referred for male infertility evaluation from 2002 to 2014 (n = 4,440). ...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2016.06.041
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To report a case of Klinefelter's syndrome with unilateral absence of vas deferens. DESIGN:Case report. SETTING:Tertiary-care infertility clinic. PATIENT(S):A 28-year-old man with the complaint of infertility. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Physical examination, genetic and hormonal evalua...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.02.017
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:To evaluate whether overweight and obesity are related to changes in serum sex hormone concentrations and semen quality. DESIGN:Cross-sectional study. SETTING:Data from five previous population-based environmental studies of semen quality were combined into one database at a university hospital in Denmark. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.07.1292
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether the insulin receptor substrate (IRS)-2 G1057D polymorphism is associated with the risk of endometriosis, and to evaluate potential correlation of IRS2 gene polymorphism with the stages of endometriosis. DESIGN:Case-control study. SETTING:Gynecology clinics in university hospital. PAT...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.09.023
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To assess the association between recent cigarette smoking (CS) in female and male partners and assisted reproduction technology (ART) outcomes. DESIGN:Cohort prospective study. SETTING:University ART program in Chile. PATIENT(S):One hundred sixty-six couples seeking pregnancy through ART. INTERVENTION(S)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.09.073
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of melatonin both on the ovaries of pinealectomized female rats through histomorphometric analysis and on steroid receptors, proliferating cell nuclear antigen (PCNA), and vascular endothelial growth factor (VEGF) expression. DESIGN:Experimental study. SETTING:Federal University of Sã...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.04.042
更新日期：2011-03-15 00:00:00
abstract：:This bulletin will review the various viral etiologies of hepatitis, their mode of transmission, and implications for infertile couples, pregnant women, and health care workers. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,实务指引,评审
doi：10.1016/j.fertnstert.2006.08.081
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To determine whether fetal fibronectin (FFN) might serve as a marker to distinguish intrauterine versus extrauterine pregnancy. DESIGN:Prospective cohort study. SETTING:Academic research center. PATIENT(S):Cervicovaginal FFN samples were obtained from 46 women who were at high risk for or presented with si...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00224-1
更新日期：1999-08-01 00:00:00
abstract：:Recent in vitro studies implicate the ovary as an extra-hepatic source of insulin-like growth factors (IGFs) with production regulated by gonadotropins and local steroids. Because previous studies have failed to show any significant variations in IGF levels in peripheral blood during the menstrual cycle, we measured t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53221-x
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:To demonstrate the laparoscopic neuroanatomy of the autonomic nerves of the pelvis using the laparoscopic neuronavigation technique, as well as the technique for a nerve-sparing radical endometriosis surgery. DESIGN:Step-by-step explanation of the technique using videos and pictures (educational video) to de...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.07.1138
更新日期：2015-11-01 00:00:00
abstract：:Of 5,341 infertile couples seen over an 8-year period, 76 (1.4%) had primary vaginismus, of whom 63 were treated with the use of a simplified sensate focus technique. There was complete symptomatic resolution of vaginismus in 60 women, and pregnancy was achieved in 33. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.03.071
更新日期：2010-11-01 00:00:00
abstract：:The data from 83 consecutive in vitro fertilization-embryo transfer cycles were examined with emphasis on the presence of subfertile male parameters, including abnormal sperm density, motility, morphologic features, or an abnormal result in the sperm penetration assay (zona-free hamster ova penetration). There were 25...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)49338-6
更新日期：1986-05-01 00:00:00
abstract：OBJECTIVE:To determine DNA fragmentation and several molecules associated with apoptosis or proliferation in ovaries of patients with diminished ovarian reserve. DESIGN:Cross-sectional analysis. SETTING:Tertiary institutional hospital. PATIENT(S):Patients with benign uterine pathology who had undergone a hysterectom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.12.075
更新日期：2006-07-01 00:00:00
