Abstract：
OBJECTIVE:To evaluate whether overweight and obesity are related to changes in serum sex hormone concentrations and semen quality. DESIGN:Cross-sectional study. SETTING:Data from five previous population-based environmental studies of semen quality were combined into one database at a university hospital in Denmark. PATIENT(S):In total, 2,139 men provided data to the database. INTERVENTION(S):Data on semen and blood samples and information on lifestyle and reproductive factors, including body mass index (BMI), were collected. MAIN OUTCOME MEASURE(S):Semen quality (volume, concentration, total sperm count, and motility) and serum concentration of sex hormones. RESULT(S):The T and inhibin B serum concentrations were 25%-32% lower in obese men in comparison with normal-weight men, whereas the E(2) concentration was 6% higher in obese men. Overweight men (BMI, 25.1-30.0 kg/m(2)) had a slightly lower adjusted sperm concentration and total sperm count than did men with a normal BMI (20.0-25.0 kg/m(2)), but no reduction in sperm count was observed among the obese men. CONCLUSION(S):These results corroborate earlier findings that overweight and obese men have a markedly changed sex hormone profile in serum, whereas reduction of semen quality, if any, was marginal and below the detection limit of this large study.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Aggerholm AS,Thulstrup AM,Toft G,Ramlau-Hansen CH,Bonde JPdoi
10.1016/j.fertnstert.2007.07.1292subject
Has Abstractpub_date
2008-09-01 00:00:00pages
619-26issue
3eissn
0015-0282issn
1556-5653pii
S0015-0282(07)01528-2journal_volume
90pub_type
杂志文章abstract：OBJECTIVE:To assess associations between lifetime sexual assault and childlessness in female veterans. DESIGN:Cross-sectional, computer-assisted telephone interview study. SETTING:Two Midwestern Veterans Administration (VA) medical centers. PATIENT(S):A total of 1,004 women aged ≤52 years, VA-enrolled between 2000 a...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2014.04.042
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:To explore the effect of letrozole as an ovulation inducing agent on oocyte and embryo quality in mice model. DESIGN:Prospective study. SETTING:Institute of Reproductive Medicine, Kolkata, India. ANIMAL(S):Sixty-nine sexually mature female Swiss Albino mice 6-7 weeks old. INTERVENTION(S):Metaphase II (MII...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.04.045
更新日期：2010-03-15 00:00:00
abstract：OBJECTIVE:To analyze prognostic factors that are associated with a discordant outcome in egg recipients sharing oocytes from the same donor. DESIGN:Matched case-control single-center study. SETTING:Private infertility clinic. PATIENT(S):Four hundred forty-four recipients (222 pairs) sharing oocytes from the same don...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.01.054
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To compare the localization and quantitation of epidermal growth factor (EGF) receptor in granulosa cells from women with normal and polycystic ovaries. DESIGN:Controlled, comparative study. SETTING:Academic research laboratory. PATIENT(S):Forty-two women with normal or polycystic ovaries who attended our ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00252-0
更新日期：1998-10-01 00:00:00
abstract：:A prospective, detailed study of both lipid and carbohydrate metabolism was carried out in 35 women who used a progesterone-T type intrauterine device (IUD). A 3-hour oral glucose tolerance test was performed in each woman before the IUD was inserted and again after 6 months of use. There was no change in the patient...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43273-5
更新日期：1978-05-01 00:00:00
abstract：:The rapid postpartum return of gonadotropic function during bromocriptine treatment was investigated through hormonal measurements in 15 women. Luteinizing hormone (LH) was measured by a novel and specific assay that does not cross-react with human chorionic gonadotropin (hCG). Prolactin was effectively suppressed by ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60610-6
更新日期：1989-04-01 00:00:00
abstract：OBJECTIVE:To analyze the effect of human papilloma virus (HPV) sperm infection on sperm parameters and in vitro fertilization (IVF) outcomes. DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENTS:Men with HPV sperm infection and couples undergoing IVF. INTERVENTIONS:Searches were conducted in...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.01.010
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To determine if human luteinized granulosa cells (GCs) exhibit angiotensin II (AII) receptors and if AII affects GC steroidogenesis. DESIGN:Luteinized GCs were either treated immediately or maintained in culture for up to 6 days before use. The presence of functional AII receptors was evaluated using the fol...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55630-1
更新日期：1993-01-01 00:00:00
abstract：:This statement explores the implications of reproduction by single individuals, unmarried heterosexual couples, and gay and lesbian couples, and concludes that ethical arguments supporting denial of access to fertility services on the basis of marital status or sexual orientation cannot be justified. This document rep...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.08.042
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:To evaluate whether DNA fragmentation and/or mitochondrial membrane potential (MMP) predict natural conception better than standard sperm parameters. DESIGN:Prospective cross-sectional study. SETTING:University medical center. PATIENT(S):Eighty-five infertile and 51 fertile men. INTERVENTION(S):Assessment...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.11.037
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To assess the level of lipid peroxidation (LP) and vitamin E in the follicular fluid and serum of infertile patients, with or without endometriosis, who were submitted to ovulation induction for assisted reproduction procedures. DESIGN:Prospective study. SETTING:Assisted conception unit, university hospital...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2007.10.072
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:To test the effects of steroid-containing media such as follicular fluid (FF) and serum and of steroid-free but human protein-rich medium on hyperactivation (HA) of human spermatozoa with and without a preincubation period. DESIGN:Analysis of HA using a computer-aided sperm analysis system. SETTING:Academic...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57191-x
更新日期：1994-12-01 00:00:00
abstract：OBJECTIVE:To determine the effect of sperm manipulation before intracytoplasmic sperm injection (ICSI) on fertilization rates. DESIGN:Three methods of sperm manipulation before direct ICSI were compared in two sibling oocyte trials. SETTING:In vitro fertilization unit within a teaching hospital. PATIENTS:Patients un...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57988-6
更新日期：1995-12-01 00:00:00
abstract：:Turner syndrome results in infertility in most cases. Fertility preservation through the cryopreservation of oocytes or ovarian tissue may be an option for some girls with Turner syndrome. Oocyte donation results in high pregnancy rates (PR). Those women who plan to pursue pregnancy need comprehensive screening and co...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2012.08.022
更新日期：2012-10-01 00:00:00
abstract：:In summary, the luteal phase defect is a deficiency of corpus luteum progesterone steroidogenesis, either in amount or duration, or both. The clinical manifestations include either primary infertility or repeated first trimester abortions. The diagnosis can only be made clinically on the basis of a well-timed endometr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)41769-3
更新日期：1976-04-01 00:00:00
abstract：OBJECTIVE:To assess the association between serum adrenal cortex autoantibodies and histologically confirmed autoimmune lymphocytic oophoritis. DESIGN:Controlled, prospective. SETTING:Tertiary research center. PATIENT(S):Two hundred sixty-six women with 46,XX spontaneous premature ovarian failure. INTERVENTION(S):O...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.04.060
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:To assess how genetic evaluations of sperm donor applicants are performed in the United States. DESIGN:A questionnaire was designed to assess: 1) the professionals involved in the family history evaluation and genetic screening; 2) the genetic testing, counseling, and informed consent processes; and 3) how t...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2013.01.093
更新日期：2013-05-01 00:00:00
abstract：:To histologically and biologically assess the impairment of testicular function after active immunization with LH, adult male rats (49) and rabbits (9) were actively immunized with bovine LH and then compared with saline-injected controls. When the measured antibody titer was high, the mating behavior of the males wa...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)38046-3
更新日期：1971-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the transcription and translation ability of mitochondria in terminally differentiated granulosa cells, these cells were incubated with ionic calcium. DESIGN:Prospective laboratory research. SETTING:In vitro fertilization laboratory in a university hospital. PATIENT(S):Granulosa cells were harv...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.03.072
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:To describe a unique case of descending salpingitis and functioning endometrium in a noncavitated mullerian remnant in a patient with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. DESIGN:Case report. SETTING:Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens,...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.11.071
更新日期：2005-05-01 00:00:00
abstract：:The effectiveness of antiestrogens and progestins in the inhibition of capacitation in the rabbit uterus and oviduct was studied. The agents tested were 8 mg/day nafoxidine HCL (NHCL), 4 mg/day fluoxymesterone (FM), 4 and 20 mg/day clomiphene citrate (CC), 8 mg/day testosterone (T), 8 mg/day dydrogesterone (D) 4 and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1972-03-01 00:00:00
abstract：OBJECTIVE:To evaluate correlations between oxygen consumption (OC) measurements before and after embryo cytokinesis, observing OC during embryo cleavages and combining that information with morphokinetics to relate to implantation potential. DESIGN:Prospective cohort study. SETTING:University-affiliated private IVF u...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.03.019
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the role of 3,3',5-triiodothyronine (T(3)) on ovarian follicle development in vitro. DESIGN:Experimental study. SETTING:University reproductive biology unit. ANIMAL(S):CD1 mice (female). INTERVENTION(S):In vitro culture. MAIN OUTCOME MEASURE(S):Assessment of follicle and oocyte development fo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.11.014
更新日期：2004-03-01 00:00:00
abstract：:Chromosomal abnormalities, sperm DNA damage, zona hardening, inadequate culture conditions, and suboptimal embryo development all play a significant role in the etiology of recurrent implantation failure. Evidence suggests that preimplantation genetic screening does not increase implantation or live birth rates. Compa...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2012.02.029
更新日期：2012-05-01 00:00:00
abstract：:The specific radioimmunoassay system was developed for the titration of the antibodies to porcine zona pellucida (ZP) in human sera by using 125I-labeled purified porcine ZP as antigen, which is known to have cross-reactivity with human ZP. The antibodies in human sera were detected in 3 of 11 (27%) women with unexpla...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47602-8
更新日期：1984-02-01 00:00:00
abstract：OBJECTIVE:To investigate the direct effects of sodium nitroprusside, a nitric oxide donor, on the fertilizing ability of human spermatozoa in vitro. DESIGN:Prospective, controlled in vitro study. SETTING:IVF Unit, Medical College Hospital. PATIENT(S):Women undergoing conventional IVF. INTERVENTION(S):Human spermato...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00537-2
更新日期：1998-03-01 00:00:00
abstract：OBJECTIVE:To determine the effect of sonographer experience during ultrasound guided embryo transfer on pregnancy outcomes. DESIGN:Retrospective chart review. SETTING:A university-based academic practice. PATIENT(S):A total of 319 women who underwent in vitro fertilization and embryo transfer (IVF-ET) from the site-...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.07.1743
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:To determine whether polymorphisms in the estrogen receptor (ER) alpha and beta genes are associated with endometriosis in a Japanese population. DESIGN:Association study. SETTING:University hospital. PATIENT(S):Japanese women diagnosed with endometriosis by laparotomy or laparoscopy. INTERVENTION(S):Dete...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.02.094
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:To examine the prevalence of migraine in women with chronic pelvic pain with and without endometriosis. DESIGN:Prospective study of headache, pelvic pain, and quality of life before laparoscopic surgery for pelvic pain. Endometriosis was diagnosed pathologically. Headaches were classified as migraine or non-...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.11.037
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of vascular endothelial growth factor (VEGF) injection into the testes on spermatogenesis and apoptosis in a varicocele-induced adolescent rat model. SETTING:University hospital urology research laboratory. ANIMAL(S):Six-week-old male Wistar rats (n = 32). INTERVENTION:The rats we...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.06.008
更新日期：2009-05-01 00:00:00
