Return of gonadotropic function in postpartum women during bromocriptine treatment.

Abstract:

:The rapid postpartum return of gonadotropic function during bromocriptine treatment was investigated through hormonal measurements in 15 women. Luteinizing hormone (LH) was measured by a novel and specific assay that does not cross-react with human chorionic gonadotropin (hCG). Prolactin was effectively suppressed by bromocriptine and hCG was cleared within 2 weeks. During the first week, both follicle-stimulating hormone (FSH) and LH were undetectable. The return of FSH and LH secretion occurred in the second postpartum week and initially was characterized by a high FSH/LH ratio. The causes of the 1-week delay in resumption of pituitary gonadotropin secretion are not known, but endogenous opioids may play a role. The possible relation between the high FSH/LH ratio and low LH pulse frequency also is discussed.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Kremer JA,Rolland R,van der Heijden PF,Thomas CM,Lancranjan I

doi

10.1016/s0015-0282(16)60610-6

subject

Has Abstract

pub_date

1989-04-01 00:00:00

pages

622-7

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)60610-6

journal_volume

51

pub_type

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