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Manipulation of sperm before intracytoplasmic sperm injection improves fertilization rates.

Abstract：

OBJECTIVE:To determine the effect of sperm manipulation before intracytoplasmic sperm injection (ICSI) on fertilization rates. DESIGN:Three methods of sperm manipulation before direct ICSI were compared in two sibling oocyte trials. SETTING:In vitro fertilization unit within a teaching hospital. PATIENTS:Patients undergoing infertility treatment using ICSI. INTERVENTIONS:Oocytes were inseminated by ICSI. MAIN OUTCOME MEASURE:Fertilization rate. RESULTS:In the first trial, a standard manipulation technique gave a 67% fertilization rate compared with 64% with a minimal manipulation technique. In the second trial the standard technique gave a significantly greater fertilization rate compared with no prior manipulation (67% versus 45%). CONCLUSIONS:Manipulation of sperm before direct ICSI is not mandatory for fertilization but significantly improves the fertilization rate.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Catt J,O'Neill C

doi

10.1016/s0015-0282(16)57988-6

subject

Has Abstract

pub_date

1995-12-01 00:00:00

pages

1210-2

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)57988-6

journal_volume

64

pub_type

杂志文章

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