Abstract：
OBJECTIVE:To examine the histopathological effects of diabetes on spermatogenesis and to detect the proliferation of germ cells with proliferative cell nuclear antigen (PCNA). DESIGN:Controlled experimental study. SETTING:The animal laboratory of the Experimental Surgery Center of Ege University, Izmir, Turkey. ANIMAL(S):Ten nondiabetic (control) and 20 diabetic adult male albino rats. INTERVENTION(S):The rats were IP injected with 40 mg/kg streptozotocin for 5 days to create a diabetic condition that was confirmed by testing blood glucose levels 5-7 days after the first injection. MAIN OUTCOME MEASURE(S):Mean testicular diameter, mean semniferous tubuli diameter (MSTD), and PCNA index. RESULT(S):Six weeks after the streptozotocin injection, both the mean testicular and the seminiferous tubuli diameters were significantly decreased in diabetic rats compared with the control group. CONCLUSION(S):The effects of diabetes on spermatogenesis can be clearly detected as a decrease in testicular diameter, MSTD, and PCNA index.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Altay B,Cetinkalp S,Doganavşargil B,Hekimgil M,Semerci Bdoi
10.1016/s0015-0282(03)00984-1keywords:
subject
Has Abstractpub_date
2003-09-01 00:00:00pages
828-31eissn
0015-0282issn
1556-5653pii
S0015028203009841journal_volume
80 Suppl 2pub_type
杂志文章abstract：OBJECTIVE:To investigate whether sphingosine-1-phosphate (S1P), an apoptosis-inhibitor, would be able to protect ovarian follicles from chemotherapy-induced cell death in vivo. DESIGN:Animal study. SETTING:Academic medical center. ANIMAL(S):Twenty female mice. INTERVENTION(S):Twenty mice were randomly assigned into...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.06.020
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To assess right-left differences in ultrasonographic markers of ovarian morphology and determine the impact on the diagnosis of polycystic ovarian morphology (PCOM). DESIGN:A cross-sectional study of data collected from 2006 to 2018. SETTING:Academic clinical research centers. PATIENT(S):Women with polycys...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2019.06.016
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To report the feasibility of ovarian cyst enucleation by using a laparoendoscopic single-site trocar through a transumbilical access. DESIGN:Case reports. SETTING:Teaching and research hospital. PATIENT(S):Three patients affected by large ovarian cysts. INTERVENTION(S):Enucleation of three large ovarian c...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.05.060
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:To investigate the impact of intracytoplasmic sperm injection (ICSI) and assisted hatching (AH) on assisted reproductive technology (ART) outcomes in initial cycles with diminished ovarian reserve (DOR) as the primary diagnosis. DESIGN:Retrospective cohort study of cycles from the Society for Assisted Reprod...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.06.043
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To determine the effect of hormone replacement therapy (HRT) on cardiac structure and function and whether these changes are related to changes in blood volume. DESIGN:Open-label pilot study. SETTING:Academic medical center. PATIENT(S):Eighteen healthy postmenopausal women. INTERVENTION(S):We administered...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(98)00398-7
更新日期：1999-01-01 00:00:00
abstract：:A prospective crossover study comparing ovulation induction techniques in eight women with premature ovarian failure is presented. These patients were treated with FSH rebound techniques using the GnRH-a, LA, alone in one treatment cycle and the same plus menopausal gonadotropins in the other treatment cycle. Two wome...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54863-8
更新日期：1992-02-01 00:00:00
abstract：:Tumor necrosis factor-alpha stimulates the secretion of vascular endothelial growth factor by cultured human oviductal epithelial cells and stromal fibroblasts. Tumor necrosis factor-alpha-stimulated vascular endothelial growth factor secretion by these cells may control oviductal fluid secretion by regulating vascula...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.05.082
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the influence of socioeconomic factors on the outcomes of infertility, including pregnancy, adoption, resolution, and loss to follow-up. DESIGN:Prospective observational study. SETTING:Infertility clinics in 11 teaching hospitals. PATIENTS:Newly registered couples with infertility of > 1 year. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：OBJECTIVE:To analyze the endometrium sonographically in patients undergoing controlled ovarian stimulation with clomiphene citrate (CC) in addition to menotropins to determine the significance of endometrial pattern and thickness on pregnancy rate (PR). DESIGN:A prospective study analyzing patients receiving sequentia...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81509-9
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:To determine the effects of menopause (aging and E) on vaginal-cervical epithelial paracellular permeability. DESIGN:Experimental, basic clinical research. SETTING:Academic research environment. PATIENT(S):Premenopausal, perimenopausal, and postmenopausal women, aged 35-65 years. INTERVENTION(S):Primary t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)02377-9
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:To study single sperm boar motility using electrical impedance measurements in a microfluidic system. DESIGN:Comparison of the optical data and electrical impedance data. SETTING:Research laboratory at a university. ANIMAL(S):Boar semen sample were used. INTERVENTION(S):A microfluidic system is developed ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.05.008
更新日期：2016-09-01 00:00:00
abstract：:In ten ovarian endometriomas of diameter exceeding 30 mm, managed by complete vaporization of the inner surface using plasma energy followed by cystectomy, we performed histologic evaluation of the depth of necrosis and the effectiveness of endometrial tissue ablation. We observed that plasma energy allows the ablatio...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2010.11.038
更新日期：2011-04-01 00:00:00
abstract：:Activities of deoxyribonucleic acid (DNA) polymerase alpha, beta, and gamma were measured in extracts of testicular biopsy specimen obtained from 37 cases of male infertility with left varicocele and compared with those of 6 normal controls. It was observed that levels of DNA polymerase alpha, beta, and gamma were sig...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60318-7
更新日期：1988-11-01 00:00:00
abstract：OBJECTIVE:To use microarray analysis as an unbiased approach to identify genes involved in the induction and growth of uterine leiomyomata. DESIGN:Screen by arrays for up to 12,000 genes in leiomyoma (L) and control myometrium (M) from nine patients. SETTING:University research laboratories. PATIENT(S):Nine patients...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03191-6
更新日期：2002-07-01 00:00:00
abstract：:Surveillance is a triennial worldwide compendium of national rules and regulations for assisted reproductive technology. It was last published in 2010. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.03.045
更新日期：2014-06-01 00:00:00
abstract：:Nonsurgical recovery of a preimplantation conceptus from the uterus of a fertile donor woman with transfer to an infertile recipient woman and subsequent pregnancy has been described previously. In this report, we describe the performance of 56 nonsurgical uterine lavages, recovery of 23 ova, and transfer of 17 ova wi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:To determine whether complete failure of fertilization of oocytes in couples with unexplained infertility persists during subsequent in vitro fertilization (IVF) cycles. DESIGN:A retrospective study of 120 cycles of IVF in 44 couples with unexplained infertility and complete failure of fertilization during t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55677-5
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of microdeletions of the long arm of chromosome Y within the AZFa, AZFb, and AZFc subregions in patients with idiopathic azoospermia, and then correlate the microdeletions with clinical phenotypes to determine the most important subregion for screening. DESIGN:Controlled clinical ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(01)01955-0
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of a phosphodiesterase type 3 inhibitor in oocyte maturation medium on subsequent embryo development. DESIGN:Animal study. SETTING:University laboratory. ANIMAL(S):CD-1 mice. INTERVENTION(S):Immature oocytes were arrested meiotically in medium containing a specific phosphodiester...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.03.041
更新日期：2009-05-01 00:00:00
abstract：:There has been increasing interest in combining the oral agents clomiphene citrate (CC) and letrozole with gonadotropins in IVF: for poor responders to reduce the amount of gonadotropins used, and in normal responders to reduce the incidence of ovarian hyperstimulation (OHSS). In normal responders, mild stimulation wi...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2017.08.017
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:To study the link between fatness and gonadotropin secretion. Overweight status is linked to polycystic ovary syndrome (PCOS) in adolescents. We postulated that heavier adolescents without symptoms would secrete LH with: [1] increased pulse frequency (LHPF) and [2] exaggerated integrated concentrations (LHAUC...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.02.072
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To assess the value of the hypo-osmotic swelling test in predicting fertilization, pregnancy, implantation, miscarriage, and live birth rates in IVF-ET cycles. DESIGN:Prospective study. SETTING:Academic tertiary referral center for fertility treatment. PATIENTS:Three hundred twenty-six couples having IVF-E...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58511-2
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVE:To determine the efficiency of oocyte retrieval (OR) timing based on the occurrence of spontaneous LH surge during natural cycle IVF (ncIVF) treatment. DESIGN:Retrospective cohort study. The cohort was divided into five subgroups according to the presumed stage of spontaneous LH surge on scheduling day (1A: ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.01.016
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To compare outcome of pregnancies after intracytoplasmic sperm injection (ICSI) with those of other assisted reproductive technologies. DESIGN:Pregnancy outcomes after ICSI were followed prospectively and compared with pregnancy outcomes after IVF with fresh and frozen ETs and donor oocyte cycles. SETTING:A...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:To determine the effect of sperm manipulation before intracytoplasmic sperm injection (ICSI) on fertilization rates. DESIGN:Three methods of sperm manipulation before direct ICSI were compared in two sibling oocyte trials. SETTING:In vitro fertilization unit within a teaching hospital. PATIENTS:Patients un...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57988-6
更新日期：1995-12-01 00:00:00
abstract：OBJECTIVE:To describe the case of a Japanese woman with combined 17alpha-hydroxylase/17,20-lyase deficiency (congenital adrenal hyperplasia type V) and to discuss possible therapeutic procedures in such patients. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 26-year-old woman with secondary amenorrhe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)00500-8
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:To determine the ectopic pregnancy rate with fresh versus frozen-thawed embryo transfers, and factors associated with ectopic pregnancy in patients undergoing IVF-ET. DESIGN:Retrospective analysis. SETTING:Institutional IVF center. PATIENT(S):A total of 3,183 patients who received 3,340 blastocysts transfe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.11.023
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To present an alternative technique for the creation of a neovagina. DESIGN:Case study. SETTING:Academic university gynecology clinic. PATIENT(S):A patient diagnosed with müllerian agenesis. INTERVENTION(S):Laparoscopically assisted creation of a neovagina by using peritoneum. MAIN OUTCOME MEASURE(S):Pat...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)00700-7
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:To describe a clinical approach to and outcomes of IVF in reproductive-aged cancer survivors receiving targeted cancer therapies. DESIGN:Case report. SETTING:Not applicable. PATIENT(S):The first case is of a female patient with metastatic lung cancer receiving long-term crizotinib, an anaplastic lymphoma k...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2016.08.011
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:To introduce a technique for hysteroscopic resection of submucous myoma arising from the uterine fundus. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 43-year-old nulliparous Japanese woman. INTERVENTION(S):An original combination technique of hysteroresectoscopy using circumferential myom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.066
更新日期：2006-11-01 00:00:00
