Abstract:
OBJECTIVE:To determine whether complete failure of fertilization of oocytes in couples with unexplained infertility persists during subsequent in vitro fertilization (IVF) cycles. DESIGN:A retrospective study of 120 cycles of IVF in 44 couples with unexplained infertility and complete failure of fertilization during their first IVF trial. SETTING:In vitro fertilization unit of the Sheba Medical Center. PATIENTS:Forty-four couples undergoing IVF for unexplained infertility. MAIN OUTCOME MEASURE(S):Fertilization rate of retrieved oocytes and pregnancy rate. RESULTS:Of the initial 44 couples, 37 underwent additional IVF cycles and 30 (81.1%) achieved fertilization. Seven patients conceived during the study period as a result of IVF and two conceived spontaneously. CONCLUSIONS:Complete failure of fertilization does not necessarily persist during subsequent IVF cycles. Therefore, at least two more IVF cycles should be attempted before reverting to other therapeutic options. However, although fertilization can be achieved in most couples, the mean oocyte fertilization rate during subsequent cycles in this group is low. This suggests an underlying undiagnosed pathology of oocyte/sperm interaction in some of these patients.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Lipitz S,Rabinovici J,Ben-Shlomo I,Bider D,Ben-Rafael Z,Mashiach S,Dor Jdoi
10.1016/s0015-0282(16)55677-5subject
Has Abstractpub_date
1993-02-01 00:00:00pages
348-52issue
2eissn
0015-0282issn
1556-5653pii
S0015-0282(16)55677-5journal_volume
59pub_type
杂志文章abstract:OBJECTIVE:To assess the efficacy of tibolone add-back therapy with Goserelin treatment of uterine fibroids. DESIGN:Randomized placebo-controlled study. SETTING:Gynecology department of an inner-city teaching hospital. PATIENT(S):Seventy-five women of reproductive age with uterine fibroids. INTERVENTION(S):All women...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2007.02.064
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To determine the effects of prior gravidity on hormonal parameters, medication regimen, oocyte parameters, fertilization, and clinical pregnancy rates (PRs) in donor and own oocyte cycles. DESIGN:A retrospective study of 64 first-attempt ovum donor cycles and 102 first-attempt IVF and ZIFT cycles using own o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58157-6
更新日期:1996-03-01 00:00:00
abstract::This study was initiated to determine whether factors are present in human sperm-free seminal plasma (HSP) that regulate the uptake and release of carnitine from sperm. Bovine caput epididymal sperm cells accumulated more carnitine than caudal sperm cells. A significant reduction in carnitine uptake by caput sperm was...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1988-05-01 00:00:00
abstract::To protect the patient from getting misleading information, these guidelines have been revised to reflect more stringent requirements for advertising and marketing. ...
journal_title:Fertility and sterility
pub_type: 指南,杂志文章
doi:10.1016/j.fertnstert.2004.07.936
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:To analyze embryo morphology in relation to the corresponding chromosomal status, in order to evaluate the effects of aneuploidy over fragmentation, delayed cleavage, and arrested cleavage. DESIGN:Retrospective study. SETTING:Reproductive Medicine Unit, Società Italiana di Studi di Medicina della Riproduzio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.07.1512
更新日期:2007-03-01 00:00:00
abstract::Maternal recognition of allotypic trophoblast lymphocyte cross-reactive (TLX) antigens is proposed to be involved in immunologic acceptance of the allogeneic fetus. The presence of TLX antigens in seminal plasma suggests that sensitization can occur before fertilization and implantation. In this study, the origin of T...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60920-2
更新日期:1989-09-01 00:00:00
abstract::With advances in cancer therapies, survival rates in prepubescent patients have steadily increased. However, a number of these surviving patients have been rendered sterile owing to their rigorous oncologic treatment regimens. In addition to cancer treatments, men and women, who are genetically fertile, can become inf...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2013.11.025
更新日期:2014-01-01 00:00:00
abstract:STUDY OBJECTIVES:To assess a single (donor) sample by the use of five computer-assisted semen analysis (CASA) systems. SETTING:British Andrology Society advanced course on computer-assisted semen analysis techniques, September 1992. PARTICIPANTS:Clinical, technical and scientific personnel with mixed experience of CA...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:To investigate whether an association exists between ovulation induction and neural tube defects (NTDs). MATERIALS AND METHODS:Risk estimations in the medical literature were identified through Medline, and validity and power were assessed. Large in vitro fertilization-embryo transfer (IVF-ET) registries rep...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)55428-4
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:To assess the clinical value of bisulfite polymerase chain reaction Luminex (BPL), an automated, high-throughput procedure for the detection of alterations in DNA methylation. DESIGN:Experimental prospective study. SETTING:University research laboratory and private in vitro fertilization (IVF) clinic. PATI...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2010.06.076
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To report a case of a gonadotroph adenoma diagnosed after a dramatic increase in estradiol level and ovarian hyperstimulation in response to a gonadotropin-releasing hormone agonist. DESIGN:Case report. SETTING:Outpatient practice and university hospital. PATIENT(S):A 35-year-old woman who presented with i...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)04342-x
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:To assess whether a measure of uterine blood flow impedance (the pulsatility index, PI) as determined by transvaginal ultrasonography with color blood flow imaging, may be used to assess endometrial receptivity immediately before the time of embryo transfer (ET) after assisted conception. DESIGN:A prospectiv...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54848-1
更新日期:1992-02-01 00:00:00
abstract::Sixty infertile women underwent infertility surgery followed by "second-look laparoscopy" (SLL). All these women had undergone detailed fertility workups, including a diagnostic laparoscopy prior to surgery. The tuboovarian adhesive disease was staged according to the severity of the disease and compared with findings...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract:OBJECTIVE:To develop a murine in vivo bioassay that is sensitive to inherent variability of hMG. DESIGN:Female F1 hybrid mice were mated after injection with fixed dosages of each of four lots of hMG. Oocytes/embryos were collected and monitored during 5 days of culture. Outcome measures were compared with retrospecti...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)56414-0
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVES:To demonstrate the effectiveness of ultrarapid cryopreservation in human embryos. DESIGN:Retrospective study. SETTING:An IVF unit of a medical center. PATIENT(S):All cases received ultrarapid freezing (URF) of embryos and frozen embryo transfer. INTERVENTION(S):Embryos were placed in phosphate-buffered s...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00257-5
更新日期:1999-08-01 00:00:00
abstract::Despite the introduction of new ovulation-inducing agents, CC remains the drug of choice for most anovulatory patients. Before initiating therapy, patients should be evaluated to determine the cause of anovulation. Patients with ovarian failure, hyperprolactinemia, hypothyroidism, or forms of CAH should be treated wit...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)48129-x
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:To determine whether antisperm autoantibody production after prepubertal vas injury is influenced by immediate repair of the vas compared to delay of the reanastomosis until sexual maturity. DESIGN:Animal study comparing early repair, late repair, and sham-operated groups. SETTING:Research laboratory in a m...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00501-4
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To determine the effect of sodium alginate encapsulation of rodent embryos on in vitro embryonic cleavage rates, implantation rates, and livebirth rates, and to find the in vivo degradation time for the capsules. DESIGN:Studies were conducted using both CB6F1 mice and Golden Syrian hamsters. RESULTS:Capsule...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)55814-2
更新日期:1993-03-01 00:00:00
abstract::Hormone patterns during 113 nonconceptual gonadotropin-induced cycles of 65 infertile anovulatory women were analyzed. All but one women ovulated, i.e., the ovulation rate was 98%. Signs of defective corpus luteum function were observed during 8 cycles, and anovulation occurred in 11 treatment cycles. The duration of ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47115-3
更新日期:1983-06-01 00:00:00
abstract:OBJECTIVE:To evaluate which factor, AMH or FSH, was superior in predicting live birth after assisted reproductive technologies (ART) when the tests are discordant, using data from the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System database. DESIGN:Retrospective cohort. SETTING:Clinic-...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2019.03.022
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To identify the gene(s) involved in the etiology of premature ovarian insufficiency in a highly consanguineous Tunisian family. DESIGN:Genetic analysis of a large consanguineous family with several affected siblings. SETTING:University hospital-based cytogenetics and molecular genetics laboratories. PATIEN...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2017.07.015
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To determine whether nerve fibers can be detected in the endometrium and myometrium in women with painful uterine fibroids and adenomyosis. DESIGN:A retrospective immunohistochemical study. SETTING:An academic training hospital. PATIENT(S):Thirty-seven women with uterine fibroids and 29 women with adenomyo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.03.026
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To analyze the role of the local renin-angiotensin system (RAS) in the female reproductive system to modulate ovarian steroidogenesis and its relationship with alpha(1)adrenergic receptors. DESIGN:Observational study. SETTING:University laboratory. ANIMAL(S):Adult female Wistar rats treated with doxazosin ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.12.021
更新日期:2007-10-01 00:00:00
abstract::Surrogacy raises a number of concerns about the psychological adjustment of the surrogate, the parents, and the child. Despite surrogacy becoming more common, research into the postdelivery psychological adjustment of the individuals involved has lagged far behind. This review examines research on the psychological ad...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2020.03.010
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To investigate the expression pattern of two oocyte-secreted factors-growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BM15)-during oocyte maturation in women with polycystic ovary syndrome (PCOS) and in controls and to evaluate the expression differences in oocytes between the two gro...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.05.036
更新日期:2011-08-01 00:00:00
abstract::Selective uterine devascularization before myomectomy at the time of cesarean section is a novel technique that facilitates myomectomy and is a safe procedure avoiding the need for subsequent surgery. ...
journal_title:Fertility and sterility
pub_type: 信件
doi:10.1016/j.fertnstert.2009.09.027
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To determine the contribution of several variables to fluid loss during transcervical resection of submucous myomas. DESIGN:An observational study using multiple linear regression analyses. SETTING:A university-affiliated training hospital and a university department of clinical epidemiology and biostatisti...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)00335-x
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:To investigate the value of the ultrasonographically determined size of seminiferous tubules and other conventional parameters for predicting sperm retrieval by microdissection testicular sperm extraction (micro-TESE). DESIGN:Clinical retrospective study. SETTING:Two urological clinics. PATIENT(S):Eight hu...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2019.08.061
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To determine if androstenedione (A) and progesterone (P) concentrations in preovulatory follicular fluid (FF) correlate with successful fertilization and cleavage of human oocytes in vitro. DESIGN:A retrospective randomized trial. SETTING:Hospital department of obstetrics and gynecology. PATIENTS:Fifty-fiv...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)54489-6
更新日期:1991-08-01 00:00:00
abstract::Cell proliferation of endometrial stromal cells treated with peritoneal fluid of women (aged 25 to 43 years) with endometriosis (n = 12) statistically significantly increased compared with the control treatment (peritoneal fluid of women without endometriosis, n = 8). Also, COX-2 gene expression and prostaglandin E(2)...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.11.039
更新日期:2011-04-01 00:00:00