Prewash total motile count is a poor predictor of live birth in intrauterine insemination cycles.

Abstract:

OBJECTIVE:To determine whether there is a relationship between prewash total motile count and live births in couples undergoing IUI. DESIGN:Retrospective review in a single academic center. SETTING:Not applicable. PATIENT(S):Couples with infertility undergoing ovulation induction with IUI between 2010 and 2014. INTERVENTION(S):Not applicable. MAIN OUTCOME MEASURE(S):Live births. RESULT(S):Our cohort included 310 women who underwent 655 IUI cycles with a cumulative live birth rate (LBR) per couple of 20% and an LBR per cycle of 10%. A analysis yielded no correlation between prewash total motile count (TMC) and live births. No live births occurred with TMC <2 million sperms. Age had a significant negative relationship to LBR. A receiver operating characteristic analysis comparing age and live births indicated a significant decline in live births for women >37 years (90% sensitivity, 70% specificity). The LBR per couple was decreased to 7% in women >37 years compared with 25% in women <37 years. CONCLUSION(S):Prewash TMC is a poor predictor of live birth. There were no live births with prewash TMC <2 million sperms. The LBR for women >37 years with IUI was significantly lower than women <37 years.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Mankus EB,Holden AE,Seeker PM,Kampschmidt JC,McLaughlin JE,Schenken RS,Knudtson JF

doi

10.1016/j.fertnstert.2018.12.025

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

708-713

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(19)30010-X

journal_volume

111

pub_type

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