Endometrial antigens involved in the autoimmunity of endometriosis.


:Serum and peritoneal fluid from five fertile women without endometriosis and serum (n = 23) and peritoneal fluid (n = 12) from infertile women with endometriosis were tested for the presence of antibodies against endometrial tissue antigens by a Western blot analysis. Antigens with molecular weights (MW) of 19, 31, 38, and 42 kd reacted with antibodies in the serum and peritoneal fluid from both fertile and infertile women. Antibodies in 20 of 23 (87%) sera and all 12 (100%) peritoneal fluid samples from endometriosis patients reacted against endometrial antigens with molecular weights (MW) of 26 kd and/or 34 kd. Serum from 10 patients (43%) and peritoneal fluid from 6 patients (50%) also had antibodies to an endometrial antigen with MW of 21.5 kd. Reactivity to other endometrial antigens with MW 16, 24, 48, and 75 kd was also noted in patients with endometriosis. Antibodies in the serum and peritoneal fluid from fertile women failed to react against these antigens. It is concluded that the humoral and local endometrial autoimmunity detected in patients with endometriosis is primarily directed against antigens with MW of 26 and 34 kd.


Fertil Steril


Fertility and sterility


Mathur S,Chihal HJ,Homm RJ,Garza DE,Rust PF,Williamson HO




Has Abstract


1988-12-01 00:00:00














  • Peritoneal fluid environment and infertility.

    abstract::The PF environment is one that hosts the processes of ovulation, gamete transportation, fertilization, and early embryonic development. The cellular and acellular constituents of this dynamic fluid are in a constant interactive state, being influenced by the physiologic events of the menstrual cycle and pelvic disease...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审


    authors: Syrop CH,Halme J

    更新日期:1987-07-01 00:00:00

  • Ectopic pregnancy in unrepaired distal tubal remnant after contralateral tubal anastomosis.

    abstract::A case is described in which, after a tubal sterilization procedure and subsequent unilateral tubal anastomosis, an ectopic gestation occurred in the contralateral, unrepaired, distal tubal segment. On the basis of this case and related evidence, the authors suggest that in cases in which only a unilateral tubal anast...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Silva PD,Paulson RJ,Anderson RE,Lobo RA

    更新日期:1987-03-01 00:00:00

  • A prospective study of prognostic factors in in vitro fertilization and embryo transfer.

    abstract::Multiple factors influence the outcome of in vitro fertilization and embryo transfer (IVF-ET). This prospective study was designed to assess their relative importance, in order to improve prognostic ability and treatment success. Prior to IVF-ET, couples were divided into "good" (GP) and "poor" (PP) prognosis groups a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Hughes EG,King C,Wood EC

    更新日期:1989-05-01 00:00:00

  • Effect of sperm treatment with exogenous platelet-activating factor on the outcome of intrauterine insemination.

    abstract:OBJECTIVE:To evaluate the effect of sperm treatment with exogenous platelet-activating factor (PAF) on IUI clinical pregnancy rate. DESIGN:Prospective randomized study. SETTING:Assisted Reproduction Unit, 2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece. SUBJECT(...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Grigoriou O,Makrakis E,Konidaris S,Hassiakos D,Papadias K,Baka S,Creatsas G

    更新日期:2005-03-01 00:00:00

  • A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion.

    abstract:OBJECTIVE:To investigate the role(s) of colony-stimulating factor 1 (CSF-1) on the development of early endometriosis in a murine model by comparing rate of lesion formation in mice [1] homozygous for a CSF-1 mutation versus syngeneic controls and [2] after treatment with imatinib, a commercially available tyrosine kin...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Jensen JR,Witz CA,Schenken RS,Tekmal RR

    更新日期:2010-01-01 00:00:00

  • Proteomic analysis of seminal plasma from infertile patients with oligoasthenoteratozoospermia due to oxidative stress and comparison with fertile volunteers.

    abstract:OBJECTIVE:To compare the expression protein profile of seminal plasma from infertile men with oligoasthenoteratozoospermia (OAT) due to oxidative stress with that of healthy, fertile men to determine the proteins indicative of infertility. DESIGN:Experimental study. SETTING:University hospital and research institute....

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Herwig R,Knoll C,Planyavsky M,Pourbiabany A,Greilberger J,Bennett KL

    更新日期:2013-08-01 00:00:00

  • Lipid peroxidation and vitamin E in serum and follicular fluid of infertile women with peritoneal endometriosis submitted to controlled ovarian hyperstimulation: a pilot study.

    abstract:OBJECTIVE:To assess the level of lipid peroxidation (LP) and vitamin E in the follicular fluid and serum of infertile patients, with or without endometriosis, who were submitted to ovulation induction for assisted reproduction procedures. DESIGN:Prospective study. SETTING:Assisted conception unit, university hospital...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章


    authors: Campos Petean C,Ferriani RA,dos Reis RM,de Moura MD,Jordão AA Jr,Navarro PA

    更新日期:2008-12-01 00:00:00

  • Anabolic steroid-induced hypogonadism: diagnosis and treatment.

    abstract:OBJECTIVE:To develop an understanding of hypogonadal men with a history of anabolic-androgenic steroid (AAS) use and to outline recommendations for management. DESIGN:Review of published literature and expert opinions. Intended as a meta-analysis, but no quality studies met the inclusion criteria. SETTING:Not applica...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审


    authors: Rahnema CD,Lipshultz LI,Crosnoe LE,Kovac JR,Kim ED

    更新日期:2014-05-01 00:00:00

  • Effect of smoking on blood lead levels in workers and role of reactive oxygen species in lead-induced sperm chromatin DNA damage.

    abstract:OBJECTIVE:To investigate whether cigarette smoking affects the blood lead levels (BLL) and whether exposure to lead introduces sperm chromatin DNA damage in factory workers. DESIGN:Cross-sectional study. SETTING:A battery plant in Taiwan. PATIENT(S):Eighty male workers employed within a battery plant. INTERVENTION(...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Hsu PC,Chang HY,Guo YL,Liu YC,Shih TS

    更新日期:2009-04-01 00:00:00

  • Vaporization of ovarian endometrioma using plasma energy: histologic findings of a pilot study.

    abstract::In ten ovarian endometriomas of diameter exceeding 30 mm, managed by complete vaporization of the inner surface using plasma energy followed by cystectomy, we performed histologic evaluation of the depth of necrosis and the effectiveness of endometrial tissue ablation. We observed that plasma energy allows the ablatio...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章


    authors: Roman H,Pura I,Tarta O,Mokdad C,Auber M,Bourdel N,Marpeau L,Sabourin JC

    更新日期:2011-04-01 00:00:00

  • Consistency and objectivity of automated embryo assessments using deep neural networks.

    abstract:OBJECTIVE:To evaluate the consistency and objectivity of deep neural networks in embryo scoring and making disposition decisions for biopsy and cryopreservation in comparison to grading by highly trained embryologists. DESIGN:Prospective double-blind study using retrospective data. SETTING:U.S.-based large academic f...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Bormann CL,Thirumalaraju P,Kanakasabapathy MK,Kandula H,Souter I,Dimitriadis I,Gupta R,Pooniwala R,Shafiee H

    更新日期:2020-04-01 00:00:00

  • Impact of retained embryos on the outcome of assisted reproductive technologies.

    abstract:OBJECTIVE:To assess the impact of embryo retention in the embryo transfer catheter followed by "immediate" retransfer on pregnancy outcome in women undergoing assisted reproduction. DESIGN:Retrospective analysis of embryo transfer following in vitro fertilization. SETTING:Assisted reproductive technology practice in ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Lee HC,Seifer DB,Shelden RM

    更新日期:2004-08-01 00:00:00

  • Changes in blood-flow impedance of the human corpus luteum throughout the luteal phase and during early pregnancy.

    abstract:OBJECTIVE:To examine changes in blood flow in the corpus luteum throughout the luteal phase and during early pregnancy. DESIGN:Longitudinal and cross-sectional prospective studies. SETTING:University hospital and city general hospital. PATIENT(S):Sixty-one women with normal menstrual cycles and normal luteal functio...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究


    authors: Tamura H,Takasaki A,Taniguchi K,Matsuoka A,Shimamura K,Sugino N

    更新日期:2008-12-01 00:00:00

  • Determination of total menstrual blood loss.

    abstract:OBJECTIVE:To develop and validate a simple method of measuring total menstrual blood loss using a pictorial representation of blood loss, the menstrual pictogram. DESIGN:A prospective evaluation of total menstrual blood loss measurement by the menstrual pictogram compared to the alkaline hematin technique. SETTING:Ac...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Wyatt KM,Dimmock PW,Walker TJ,O'Brien PM

    更新日期:2001-07-01 00:00:00

  • Preclinical abortions and endometriosis.

    abstract::A single human chorionic gonadotropin determination was performed in 786 infertile women during the late luteal phase to determine the frequencies of preclinical abortions and whether the frequency was increased in women with endometriosis. Thirty-seven pregnancies (4.7% of cycles) were identified, of which six were c...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Pittaway DE,Ellington CP,Klimek M

    更新日期:1988-02-01 00:00:00

  • Selecting cryopreserved semen for assisted reproductive techniques based on the level of sperm nuclear DNA fragmentation resulted in pregnancy.

    abstract::A cryopreserved sperm sample with a low level of DNA fragmentation was used for intracytoplasmic sperm injection and resulted in a twin birth from a couple with a 10-year history of idiopathic infertility. ...

    journal_title:Fertility and sterility

    pub_type: 信件


    authors: Alvarez JG,Ollero M,Larson-Cook KL,Evenson DP

    更新日期:2004-03-01 00:00:00

  • Endometriosis and obstetrics complications: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To evaluate the effect of endometriosis on pregnancy outcomes. DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENT(S):Women with or without endometriosis. INTERVENTION(S):Electronic databases searched from their inception until February 2017 with no limit for language and with all ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审


    authors: Zullo F,Spagnolo E,Saccone G,Acunzo M,Xodo S,Ceccaroni M,Berghella V

    更新日期:2017-10-01 00:00:00

  • Laparoscopic management of heterotopic cesarean scar pregnancy with preservation of intrauterine gestation and delivery at term: case report.

    abstract:OBJECTIVE:To present a case of laparoscopic removal of a heterotopic cesarean scar pregnancy under ultrasound guidance. DESIGN:Case report. SETTING:Private hospital. PATIENT(S):A 34-year-old woman with heterotopic cesarean scar pregnancy. INTERVENTION(S):Laparoscopic removal of heterotopic cesarean scar pregnancy. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Demirel LC,Bodur H,Selam B,Lembet A,Ergin T

    更新日期:2009-04-01 00:00:00

  • Minimum standards for practices offering assisted reproductive technologies: a committee opinion.

    abstract::This document is designed to provide a framework for assisted reproductive technology (ART) programs that meet or exceed the requirements suggested by the Centers for Disease Control and Prevention (CDC) for certification of ART laboratories. This document replaces the document, "Revised Minimum Standards for Practices...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,实务指引


    authors: Practice Committee of the American Society for Reproductive Medicine.,Practice Committee of the Society for Assisted Reproductive Technology.,Practice Committee of the Society of Reproductive Biologists and Technologists. Electronic address: asrm@as

    更新日期:2020-03-01 00:00:00

  • Vaginal-cervical epithelial permeability decreases after menopause.

    abstract:OBJECTIVE:To determine the effects of menopause (aging and E) on vaginal-cervical epithelial paracellular permeability. DESIGN:Experimental, basic clinical research. SETTING:Academic research environment. PATIENT(S):Premenopausal, perimenopausal, and postmenopausal women, aged 35-65 years. INTERVENTION(S):Primary t...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Gorodeski GI

    更新日期:2001-10-01 00:00:00

  • Isopropanolic Cimicifuga racemosa is favorable on bone markers but neutral on an osteoblastic cell line.

    abstract::Postmenopausal women treated with an isopropanolic extract of Cimicifuga racemosa underwent a decrease in the urinary concentration of N-telopeptides, a marker of bone resorption, and an increase in alkaline phosphatase, a marker of bone formation, at the third month of therapy. Serum from treated women did not modify...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: García-Pérez MA,Pineda B,Hermenegildo C,Tarín JJ,Cano A

    更新日期:2009-04-01 00:00:00

  • Effect of chilling on the organization of tubulin and chromosomes in rhesus monkey oocytes.

    abstract:OBJECTIVE:To determine the effects of chilling on the organization and distribution of tubulin and chromosomes in rhesus monkey oocytes. DESIGN:Comparative laboratory study. SETTING:Academic research laboratory. ANIMAL(S):Eight adult female rhesus monkeys (Macaca mulatta) aged 6-16 years. INTERVENTION(S):A total of...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Songsasen N,Yu IJ,Ratterree MS,VandeVoort CA,Leibo SP

    更新日期:2002-04-01 00:00:00

  • Nasal embryonic LHRH factor (NELF) mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome.

    abstract:OBJECTIVE:To determine if mutations in NELF, a gene isolated from migratory GnRH neurons, cause normosmic idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome (KS). DESIGN:Molecular analysis correlated with phenotype. SETTING:Academic medical center. PATIENT(S):A total of 168 IHH/KS patients as well ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Xu N,Kim HG,Bhagavath B,Cho SG,Lee JH,Ha K,Meliciani I,Wenzel W,Podolsky RH,Chorich LP,Stackhouse KA,Grove AM,Odom LN,Ozata M,Bick DP,Sherins RJ,Kim SH,Cameron RS,Layman LC

    更新日期:2011-04-01 00:00:00

  • Ovarian expression of markers associated with proliferation or apoptosis in women with diminished ovarian reserve.

    abstract:OBJECTIVE:To determine DNA fragmentation and several molecules associated with apoptosis or proliferation in ovaries of patients with diminished ovarian reserve. DESIGN:Cross-sectional analysis. SETTING:Tertiary institutional hospital. PATIENT(S):Patients with benign uterine pathology who had undergone a hysterectom...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Vital-Reyes V,Rodríguez-Burford C,Chhieng DC,Alvarado-Cabrero I,Reyes-Fuentes A,Grizzle WE

    更新日期:2006-07-01 00:00:00

  • Effects of immunization with the beta-subunit of ovine luteinizing hormone on corpus luteum function in the rhesus monkey.

    abstract::Rhesus monkeys immunized with the beta-subunit of ovine luteinizing hormone (oLHbeta) developed circulating antibodies which cross-reacted strongly with rhesus monkey chorionic gonadotropin. Normal ovulatory cycles continued, but the fertility of immunized monkeys as compared with that of controls was significantly re...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Thau RB,Sundaram K,Thornton YS,Seidman LS

    更新日期:1979-02-01 00:00:00

  • Effect of injectable contraceptives Depo-Provera and norethisterone oenanthate on pituitary gonadotropin response to luteinizing hormone-releasing hormone.

    abstract::The pituitary response to luteinizing hormone-releasing hormone (LHRH) was tested in women before and approximately 2, 8, and 12 weeks after the injection of either Depo-Provera or norethisterone oenanthate. The secretion of both luteinizing hormone and follicle-stimulating hormone in response to LHRH was similar in t...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Toppozada M,Parmar C,Fotherby K

    更新日期:1978-11-01 00:00:00

  • Adolescent infertility--to treat or not to treat.

    abstract:OBJECTIVE:To present the set of reasons for and against fertility treatment for a very young patient. DESIGN:An expert opinion based on clinical experience. SETTING:An academic-affiliated fertility clinic situated in East Jerusalem. PATIENT(S):A 16-year-old married teenager with 2 years' duration of infertility due ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Haimov-Kochman R,Imbar T,Farchat M,Bdolah Y,Hurwitz A

    更新日期:2008-11-01 00:00:00

  • Congenital anomalies and assisted reproductive technology: more of the same.

    abstract::Klemetti's birth registry study is put in context of other major studies. Summary advice is offered to practitioners as to what they should tell parents who conceive with assisted reproductive technology. ...

    journal_title:Fertility and sterility

    pub_type: 评论,信件


    authors: Sutcliffe AG

    更新日期:2005-11-01 00:00:00

  • The effect of centchroman on serum luteinizing hormone in normal males.

    abstract::Elevation of serum luteinizing hormone levels was observed in five normal male volunteers while they were taking Centchroman. This effect resembles that of clomiphene and suggests a new biologic potential of Centchroman. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Vaidya RA,Sheth A,Meherji P,Joshi L,Devi PK

    更新日期:1976-04-01 00:00:00

  • Weak linkage in androgen receptor: identification of mutation-prone points.

    abstract:OBJECTIVE:Mutation within androgen receptor (AR) can be seen. Presently, prediction of protein nanostructure and function is a great challenge in the proteomics and structural genomics era. To identify the points vulnerable to mutation is a new trend to expand the knowledge on disorders in genomic and proteomic level o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Wiwanitkit V

    更新日期:2009-01-01 00:00:00