Abstract：
OBJECTIVE:To report the restoration of ovarian function and pregnancy in a woman after bilateral oophorectomy for benign disease after autotransplantation of cryopreserved ovarian cortex. DESIGN:Case report. SETTING:Gynecology research unit in a university hospital. PATIENT(S):A 28-year-old woman who underwent bilateral adnexectomy for ovarian abscesses at the age of 18 years. INTERVENTION(S):We performed ovarian cortex autotransplantation to a peritoneal pocket in the broad ligament. MAIN OUTCOME MEASURE(S):Restoration of ovarian activity and pregnancy. RESULT(S):Restoration of ovarian function began at 20 weeks and was achieved 24 weeks after transplantation. After the fifth stimulation attempt, two mature oocytes were obtained and microinjected. One embryo (seven cells) was obtained and transferred, leading to a normal pregnancy. The patient delivered a healthy baby boy weighing 2,370 g at 38 weeks of gestation. CONCLUSION(S):Ovarian cortex cryopreservation can be performed at the time of surgery for benign diseases when fertility is impaired. We report the first pregnancy to occur after ovarian tissue cryopreservation for benign ovarian pathology after bilateral oophorectomy.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Donnez J,Jadoul P,Pirard C,Hutchings G,Demylle D,Squifflet J,Smitz J,Dolmans MMdoi
10.1016/j.fertnstert.2012.05.017subject
Has Abstractpub_date
2012-09-01 00:00:00pages
720-5issue
3eissn
0015-0282issn
1556-5653pii
S0015-0282(12)00571-7journal_volume
98pub_type
杂志文章abstract：:To compare the effects of testosterone (T) and dihydrotestosterone (DHT) on the maintenance and the restoration of spermatogenesis, hypophysectomized (APX) rats were treated daily for 35 days with 0.5 mg of T propionate (TP) or DHT propionate (DHTP) beginning 5 or 33 days after hypophysectomy. In the maintenance exper...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42865-7
更新日期：1977-10-01 00:00:00
abstract：OBJECTIVE:To prospectively assess whether metformin diet safely provides primary and secondary prevention of gestational diabetes (GD). DESIGN:Assess development of GD on metformin diet. SETTING:Outpatient clinical research center. PATIENT(S):One hundred forty-two nondiabetic women with polycystic ovary syndrome (PC...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2007.03.036
更新日期：2008-03-01 00:00:00
abstract：:Effective contraception and easily available abortion have contributed to the decline of adoptable children. This decline has resulted in a marked increase in the demand for AID. The provider of donor semen must establish minimal semen criteria to meet this demand effectively. During the past 8 years the authors have ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)45923-6
更新日期：1981-12-01 00:00:00
abstract：:The antiprogesterone compound RU 486 (17 beta-hydroxy-11 beta-[4-dimethylaminophenyl]-17 alpha-[ 1-propynyl]estra-4,9-dien-3-one; Roussel-Uclaf, Paris, France) was used to induce menstruation in a randomized controlled trial. Castrated adult female cynomolgus monkeys (n = 17) received sequential subcutaneous Silastic ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47246-8
更新日期：1983-08-01 00:00:00
abstract：OBJECTIVE:To describe laparoscopic management of a case of leyomiomatosis peritonealis disseminata associated with ovarian endometriosis. DESIGN:Surgical video article. SETTING:Academic hospital. PATIENT:We present a case of a 30-year-old woman referred to our clinic for abdominal and pelvic pain and dyspareunia. A ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2019.03.023
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To compare endocrine profiles and IVF outcomes after using GnRH agonists (GnRHa) to trigger final oocyte maturation in women with polycystic ovary syndrome (PCOS) with other hyper-responders. DESIGN:Retrospective cohort study. SETTING:Academic center. PATIENT(S):Forty women with PCOS and 74 hyper-responder...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.09.042
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:Evaluation of the Creatsas modification of Williams vaginoplasty for the creation of neovagina in patients with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH syndrome). DESIGN:Record of perioperative and postoperative results and complications. Follow-up evaluations of patients yearly after the operation. S...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)02836-9
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:To review recent advances in understanding the role of leptin in the physiology and pathophysiology of reproduction, with a focus on relevant clinical situations. DESIGN:A MEDLINE computer search was performed to identify relevant articles. RESULT(S):Leptin, an adipocyte hormone important in regulating ener...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(01)03010-2
更新日期：2002-03-01 00:00:00
abstract：:Elevation of serum luteinizing hormone levels was observed in five normal male volunteers while they were taking Centchroman. This effect resembles that of clomiphene and suggests a new biologic potential of Centchroman. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)41785-1
更新日期：1976-04-01 00:00:00
abstract：OBJECTIVE:To measure the levels of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) induced by thrombin in endometrial stromal cells (ESC). DESIGN:Evaluation of the effects of thrombin, thrombin receptor activator peptide 6 (TRAP-6), and D-phenylalanyl-1-propyl-L arginine chloromethyl ket...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.11.080
更新日期：2009-02-01 00:00:00
abstract：:Solid-phase enzyme immunoassays, based on monoclonal antibodies reactive with different forms of human placental-type alkaline phosphatases, were applied to their detection in human seminal plasma from fertile and infertile men. The placental-like form of alkaline phosphatase (PLAP-like AP), known to occur in testicul...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the outcome of repeated electroejaculation for obtaining semen from adolescents and young men before initiation of anticancer therapies. DESIGN:Retrospective clinical study. SETTING:Bikur Cholim Hospital, Jerusalem, Israel. PATIENT(S):Six young male patients (average age, 18+/-3 years) with dia...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)01680-6
更新日期：2001-04-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of estrogen (E) alone or with cyclic, continuous, or interrupted P regimens on bone density in an aged rat model. DESIGN:Randomized controlled trial. ANIMALS:Twenty 12-month-old female Sprague-Dawley rats were sham operated (intact control) and 100 were ovariectomized (OVX). INTE...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:To assess the ability of a GnRH antagonist (Cetrorelix, Asta Medica AG, Frankfurt, Germany) to prevent premature LH surges in an IVF-ET program using a simple protocol with one or two administrations. DESIGN:Controlled ovarian hyperstimulation was carried out in 17 women with three ampules a day of hMG, star...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)56933-7
更新日期：1994-09-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of endogenous hormone levels on central abdominal fat during the menopausal transition in a population-based cohort of Australian-born women. DESIGN:Prospective observational study. SETTING:Population-based sample. Body composition was assessed in the Royal Melbourne Hospital, and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(03)00361-3
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:To investigate the feasibility of utilizing low-dose hCG alone to complete follicle maturity in a natural cycle, without the need for antecedent exogenous FSH stimulation. DESIGN:Case series. SETTING:Academic fertility program. PATIENT(S):Normally ovulatory women with infertility thought to be predominantl...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.01.021
更新日期：2016-05-01 00:00:00
abstract：:The reinsemination of human oocytes that failed to show any evidence of fertilization 12 to 14 hours after insemination was examined to determine whether this would increase success of in vitro fertilization or be of use in determining the fertilizing capacity of the husband's spermatozoa. Reinsemination with spermato...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47891-x
更新日期：1984-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of a pill with drospirenone (3 mg) plus ethinyl E(2) (20 μg) (DRP/20EE) alone or associated with metformin or cyproterone acetate (CPA) on some metabolic cardiovascular risk factors in women with polycystic ovary syndrome (PCOS). DESIGN:Randomized, open-label clinical trial. SETTING:...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2009.10.016
更新日期：2010-10-01 00:00:00
abstract：:Where histology used the presence of glands and/or stroma in the myometrium as pathognomonic for adenomyosis, imaging uses the appearance of the myometrium, the presence of striations, related to the presence of endometrial tissue within the myometrium, the presence of intramyometrial cystic structures and the size an...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2018.01.006
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To report the case of a patient submitted to laparoscopic bowel resection in whom histology revealed endometriosis and schistosomiasis. DESIGN:Case report. SETTING:Multidisciplinary group practice and teaching hospital. PATIENT(S):A 31-year-old patient with pelvic pain. INTERVENTION(S):Laparoscopic bowel ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.08.068
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To study and compare the effects of three sperm separation media, two silica-based (Percoll; Pharmacia Biotech AB, Uppsala, Sweden, and Isolate; Irvine Scientific, Santa Ana, CA) and one non-silica-based (Ixaprep; Medicult, Copenhagen, Denmark), on the recovery of progressive motile sperm, the percentage of s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00375-1
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:To compare the effects of gonadotropin-releasing hormone agonist (GnRH-a) initiation either preceding or concurrent with controlled ovarian hyperstimulation (COH) in patients undergoing in vitro fertilization-embryo transfer (IVF-ET). DESIGN:Fifty-five patients were prospectively randomized to receive either...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)55322-9
更新日期：1992-10-01 00:00:00
abstract：:hCG levels in cul-de-sac and peripheral blood in patients with ectopic pregnancies were studied. hCG levels were significantly higher in the cul-de-sac blood than in peripheral blood (P less than 0.01). The high hCG level in the cul-de-sac blood was not due to interference by proteolytic enzymes in cul-de-sac blood si...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59671-x
更新日期：1988-01-01 00:00:00
abstract：:Prior studies have demonstrated that gonadotropin stimulation quality and pregnancy rates are better in in vitro fertilization (IVF) patients with low basal cycle day 3 follicle-stimulating hormone (FSH) levels. The records of 81 patients who had undergone three or more IVF attempts during a 2-year period were studied...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53707-8
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:To determine if adult human endometrium possesses an intact müllerian-inhibiting substance (MIS) signal transduction system and, if so, whether MIS can modulate endometrial cell viability. DESIGN:Adult human endometrial tissue was subjected to reverse transcription polymerase chain reaction (RT-PCR) analysis...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.01.028
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To report the birth of a healthy female infant from a father with nonmosaic Klinefelter syndrome (KS) and document the experience of men with KS undergoing assisted conception. DESIGN:Retrospective. SETTING:Private IVF center. PATIENT(S):Twelve couples with male factor infertility due to Klinefelter syndro...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(03)01157-9
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:To measure serum anti-Müllerian hormone (AMH) during different phases of the menstrual cycle and to correlate the measurements with ovarian response and clinical-pregnancy rates in intracytoplasmic sperm injection cycles. DESIGN:Prospective cohort study. SETTING:University IVF unit. PATIENT(S):Thirty-three...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.05.040
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:To compare the low-dose recombinant FSH and hMG protocols in treatment of patients with history of severe ovarian hyperstimulation syndrome (OHSS). DESIGN:A prospective study on 22 patients with history of severe OHSS. Group A (n = 14) was treated with low-dose recombinant FSH 40 cycles and group B (n = 8) w...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)58631-2
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVE:To examine the spatiotemporal expression of CD9 protein in the peri-implantation mouse uterus as well as the effects of ovarian steroid hormones on CD9. DESIGN:Experimental animal study. SETTING:Reproductive biological center of Chinese Academy of Sciences. ANIMAL(S):Female Kunming white strain mice (6-8 w...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.07.1525
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the use of sonohysterography for uterine screening before IVF. DESIGN:Prospective screening with sonohysterography and comparison with available hysterosalpingographic and hysteroscopic evaluations. SETTING:Private practice. PATIENT(S):Seventy-two women undergoing IVF-ET using their own or dono...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00045-4
更新日期：1998-05-01 00:00:00
