The desire of infertile patients for multiple births.

Abstract:

OBJECTIVE:To determine the proportion of infertile women who prefer a multiple birth over a singleton, patient characteristics associated with this desire, and patient knowledge about the risks of multiple births. DESIGN:Prospective analysis. SETTING:Academic university hospital-based infertility center and private general gynecology clinic. PATIENT(S):Four hundred sixty-four female patients with infertility who presented for their initial visit. MAIN OUTCOME MEASURE(S):Demographic characteristics, infertility history, desire regarding multiple births, knowledge of the risks of multiple births, and goals of infertility evaluation and treatment were determined by using a 41-question survey. Univariate analysis was performed to assess patient characteristics associated with the desire for multiple births. Independent factors associated with this desire were assessed by multivariable logistic regression analysis. RESULT(S):20.3% of women desired multiples over a singleton gestation. Nulliparity, lower family income, younger patient age, prior evaluation for infertility, longer duration of infertility, and lack of knowledge regarding risks of twin gestations were associated with this desire. Only nulliparity and lower family income were independently associated. CONCLUSION(S):A sizable minority of infertility patients prefers a multiple birth as their treatment outcome. Patient education may be an effective strategy to reduce the incidence of twin and higher-order multiple pregnancies.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Ryan GL,Zhang SH,Dokras A,Syrop CH,Van Voorhis BJ

doi

10.1016/j.fertnstert.2003.05.035

keywords:

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

500-4

issue

3

eissn

0015-0282

issn

1556-5653

pii

S001502820303067X

journal_volume

81

pub_type

杂志文章
  • The different routes of administration and the effect of hormone replacement therapy on osteoporosis.

    abstract:OBJECTIVE:To review osteoporosis, a disease characterized by low bone mass, microarchitectural deterioration of bone tissue leading to increased bone fragility and a consequent increase in fracture risk. The disorder has become a major health problem in the West, where increased life expectancy has placed new emphasis ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:

    authors: Christiansen C

    更新日期:1994-12-01 00:00:00

  • The metoclopramide test: a useful tool with the luteinizing hormone-releasing hormone test in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism.

    abstract::To evaluate the effectiveness of intravenous metoclopramide, alone or in combination with luteinizing hormone-releasing hormone (LH-RH), in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism, 12 patients with constitutional delay of puberty and 10 patients with hypogonadotropic hy...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60788-4

    authors: Lanes R,Palacios A,Avendano E,Moncada G,Chique G

    更新日期:1989-07-01 00:00:00

  • Occult abnormal pregnancies after first post-embryo transfer serum beta-human chorionic gonadotropin levels of 1.0-5.0 mIU/mL.

    abstract:OBJECTIVE:To assess the occult pregnancy rate after "negative" first post-embryo transfer (ET) serum β-hCG results. DESIGN:Two-part retrospective cohort study and nested case series. SETTING:University-based fertility center. PATIENT(S):A total of 1,571 negative first post-ET serum β-hCG results were included in the...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2015.11.049

    authors: Maslow BS,Bartolucci A,Sueldo C,Engmann L,Benadiva C,Nulsen JC 3rd

    更新日期:2016-04-01 00:00:00

  • An examination of blood steroid and gonadotropin concentrations in relation to fertility status and testicular function in men.

    abstract::Plasma concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), testosterone (T), and 17 beta-estradiol (E2) have been measured in men complaining of infertility in comparison with men of proven fertility. Subgrouping of patients was achieved on the basis of the presence or abse...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)46582-9

    authors: Pierrepoint CG,Jenkins BM,Wilson DW,Phillips MJ,Gow JG

    更新日期:1982-10-01 00:00:00

  • Buoyant density and sedimentation dynamics of HIV-1 in two density-gradient media for semen processing.

    abstract:OBJECTIVE:To compare buoyant density and sedimentation kinetics of human immunodeficiency virus 1 (HIV-1) in two sperm-washing media, Percoll and Pureception. DESIGN:Laboratory study. SETTING:University hospital. PATIENT(S):None. INTERVENTION(S):Buoyant density and sedimentation kinetics of HIV-1 particles (MOLT-4/...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.09.025

    authors: Kuji N,Yoshii T,Hamatani T,Hanabusa H,Yoshimura Y,Kato S

    更新日期:2008-11-01 00:00:00

  • Older first-time mothers and early postpartum depression: a prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies.

    abstract:OBJECTIVE:To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression. DESIGN:Prospective cohort study. SETTING:Assisted reproductive technology (ART) c...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2011.08.037

    authors: McMahon CA,Boivin J,Gibson FL,Fisher JR,Hammarberg K,Wynter K,Saunders DM

    更新日期:2011-11-01 00:00:00

  • Mechanisms regulating invasiveness and growth of endometriosis lesions in rat experimental model and in humans.

    abstract:OBJECTIVE:To compare the expression of MMP-2, TIMP-2, and TGFbeta2 mRNA in experimental and human endometriotic lesions and to assess the possibility of its cytokine regulation. DESIGN:Experimental laboratory study. SETTING:Medical center. ANIMALS AND PATIENT(S): Thirty female Wistar rats, 17 women with endometriosis...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2009.11.024

    authors: Sotnikova NY,Antsiferova YS,Posiseeva LV,Shishkov DN,Posiseev DV,Filippova ES

    更新日期:2010-05-15 00:00:00

  • Successful microsurgical removal of a pronucleus from tripronuclear human zygotes.

    abstract::We have microsurgically extracted a pronucleus from 11 tripronuclear human zygotes under two different experimental conditions. One group of six zygotes was incubated in cytochalasin D for 30 minutes before manipulation. The remaining five zygotes were manipulated without preincubation in cytoskeletal relaxing agents....

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60901-9

    authors: Gordon JW,Grunfeld L,Garrisi GJ,Navot D,Laufer N

    更新日期:1989-09-01 00:00:00

  • Abnormal distribution of epididymal antigens on spermatozoa from infertile men.

    abstract::An antiserum raised against human epididymal proteins associated with ejaculated sperm was used to test the hypothesis that the amount and/or localization of these antigens may be altered in men with infertility. With the use of immunofluorescence we found that in sperm from fertile donors 88.4% of the cells had the a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Blaquier JA,Cameo MS,Stephany D,Piazza A,Tezon J,Sherins RJ

    更新日期:1987-02-01 00:00:00

  • Complete evaluation of anatomy and morphology of the infertile patient in a single visit; the modern infertility pelvic ultrasound examination.

    abstract::The comprehensive "one-stop shop" ultrasound evaluation of an infertile woman, performed around cycle days 5 to 9, will reveal abundant information about the anatomy and morphology of the pelvic organs and thereby avoid costly radiation and iodinated contrast exposure. We propose a two-dimensional and three-dimensiona...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2016.03.026

    authors: Groszmann YS,Benacerraf BR

    更新日期:2016-06-01 00:00:00

  • Study of spermatogenesis and thickening of lamina propria in the human seminiferous tubules.

    abstract::The negative correlation between the thickness of the lamina propria and Johnsen's score count in individual seminiferous tubules was observed and the tubules with thin lamina propria indicated almost complete spermatogenesis. It is suggested that the thin lamina propria may be one of the good indicators of complete s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.10.019

    authors: Sato Y,Nozawa S,Iwamoto T

    更新日期:2008-10-01 00:00:00

  • Changes of bioactive luteinizing hormone after laparoscopic ovarian cautery in patients with polycystic ovarian syndrome.

    abstract::The serum levels of bioactive luteinizing hormone (LH), immunoreactive LH, follicle-stimulating hormone, androstenedione (A), and testosterone (T) were determined in nine anovulatory women with polycystic ovarian syndrome (PCOS) before and after laparoscopic ovarian cautery. Eight ovulated spontaneously and three conc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53451-7

    authors: Sakata M,Tasaka K,Kurachi H,Terakawa N,Miyake A,Tanizawa O

    更新日期:1990-04-01 00:00:00

  • Leyomiomatosis peritonealis disseminata associated with ovarian endometriosis in a patient submitted to hysteroscopic myomectomy.

    abstract:OBJECTIVE:To describe laparoscopic management of a case of leyomiomatosis peritonealis disseminata associated with ovarian endometriosis. DESIGN:Surgical video article. SETTING:Academic hospital. PATIENT:We present a case of a 30-year-old woman referred to our clinic for abdominal and pelvic pain and dyspareunia. A ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2019.03.023

    authors: Mabrouk M,Arena A,Raimondo D,Parisotto M,Caprara G,Seracchioli R

    更新日期:2019-06-01 00:00:00

  • Endometriosis and the development of tuboperitoneal fistulas after tubal ligation.

    abstract::The present study details gross and histologic findings of 79 previously ligated fallopian tubes from 3 groups of patients. Of 20 oviducts removed after documented sterilization failure (group I), 6 revealed a process compatible with endometriosis. Four of nine previously ligated fallopian tubes removed at the Johns H...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)45251-9

    authors: Rock JA,Parmley TH,King TM,Laufe LE,Su BS

    更新日期:1981-01-01 00:00:00

  • Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study.

    abstract:OBJECTIVE:To assess whether provision of an educational DVD was more effective in increasing the uptake of elective single embryo transfers (eSET) than an educational brochure in an IVF population. DESIGN:Randomized controlled trial. SETTING:Private IVF clinic. PATIENT(S):One hundred thirty-one couples starting thei...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2009.03.080

    authors: Hope N,Rombauts L

    更新日期:2010-07-01 00:00:00

  • Regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic protein 1 in follicular fluid accumulate differentially in patients with and without endometriosis undergoing in vitro fertilization.

    abstract:OBJECTIVE:To compare the amount of regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic protein 1 (MCP-1) in follicular fluid (FF) of patients with and without endometriosis and to determine their oocyte fertilization and pregnancy rates. DESIGN:Case-control study. SETTING...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.05.043

    authors: Xu H,Schultze-Mosgau A,Agic A,Diedrich K,Taylor RN,Hornung D

    更新日期:2006-12-01 00:00:00

  • Aromatase inhibitor letrozole: a novel treatment for ectopic pregnancy.

    abstract:OBJECTIVE:To study the use of the aromatase inhibitor letrozole for treatment of ectopic pregnancy compared with methotrexate. DESIGN:Nonrandomized prospective cohort study. SETTING:University hospital. PATIENT(S):A series of 42 consecutive patients with undisturbed ectopic pregnancy. INTERVENTION(S):Counseling on ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.04.001

    authors: Mitwally MF,Hozayen WG,Hassanin KMA,Abdalla KA,Abdalla NK

    更新日期:2020-08-01 00:00:00

  • A polymorphism of the interleukin-1beta gene and idiopathic recurrent miscarriage.

    abstract:OBJECTIVE:Proinflammatory cytokines have been described to be involved in the pathogenesis of idiopathic recurrent miscarriage (IRM). We investigated the association between IRM and a polymorphism in exon 5 of the interleukin-1beta gene (IL1B) and interleukin-1beta (IL-1beta) serum levels. DESIGN:Case control study. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(01)01914-8

    authors: Hefler LA,Tempfer CB,Unfried G,Schneeberger C,Lessl K,Nagele F,Huber JC

    更新日期:2001-08-01 00:00:00

  • Novel and conventional embryo parameters as input data for artificial neural networks: an artificial intelligence model applied for prediction of the implantation potential.

    abstract:OBJECTIVE:To describe novel embryo features capable of predicting implantation potential as input data for an artificial neural network (ANN) model. DESIGN:Retrospective cohort study. SETTING:University-affiliated private IVF center. PATIENT(S):This study included 637 patients from the oocyte donation program who un...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.08.023

    authors: Bori L,Paya E,Alegre L,Viloria TA,Remohi JA,Naranjo V,Meseguer M

    更新日期:2020-12-01 00:00:00

  • Clinical experience with the copper 7 intrauterine device.

    abstract::This paper reports further observations on our previous study of 203 Copper 7 intrauterine insertions performed in 199 women. There have now been accumulated 3799 woman-months of use. At least a 2-year period of observation has been attained from first insertion until these data were analyzed. The Copper 7 intrauterin...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Nebel WA,Currie JL,Lassiter RE

    更新日期:1978-11-01 00:00:00

  • Effect of vitrification and beta-mercaptoethanol on reactive oxygen species activity and in vitro development of oocytes vitrified before or after in vitro fertilization.

    abstract:OBJECTIVE:To investigate the effect of vitrification and beta-mercaptoethanol (beta-ME) on reactive oxygen species (ROS) activity and in vitro development of oocytes vitrified before or after in vitro fertilization (IVF). DESIGN:Randomized prospective study. SETTING:University-based assisted reproductive technology l...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.01.043

    authors: Gupta MK,Uhm SJ,Lee HT

    更新日期:2010-05-15 00:00:00

  • The origin of orchiopexy-induced testicular lesions in the pig.

    abstract::Cooling experiments of abdominal testes in adult, naturally cryptorchid pigs indicate that spermatogenic arrest in abdominal testes is not due to an inborn defect, but is caused solely by maintenance of the testis at abdominal temperature. It is postulated that failure of spermatogenic cells to differentiate after orc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)44364-5

    authors: Frankenhuis MT,Wiegerinck MA,Schoorl M,Kremer J,Wensing CJ

    更新日期:1979-11-01 00:00:00

  • Previous ectopic pregnancy as a predictor of failure of systemic methotrexate therapy.

    abstract:OBJECTIVE:To investigate whether a history of previous ectopic pregnancy is an independent risk factor for failure of methotrexate therapy in subsequent ectopic pregnancies and whether the previous treatment method influenced failure. SETTING:Inner-city teaching hospital. DESIGN:Retrospective case review. PATIENT(S)...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2003.09.070

    authors: Lipscomb GH,Givens VA,Meyer NL,Bran D

    更新日期:2004-05-01 00:00:00

  • Treatment of hirsutism with ethinyl estradiol-desogestrel contraceptive pills has beneficial effects on the lipid profile and improves insulin sensitivity.

    abstract:OBJECTIVE:To evaluate the effects on the lipid pattern and insulin sensitivity of hirsute women of an oral contraceptive pill containing 30 microg of ethinyl estradiol and 150 microg of desogestrel. DESIGN:Prospective clinical study. SETTING:Tertiary care institutional hospital. PATIENT(S):16 hirsute women. INTERVE...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(00)00718-4

    authors: Escobar-Morreale HF,Lasunción MA,Sancho J

    更新日期:2000-10-01 00:00:00

  • Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone.

    abstract:OBJECTIVE:To study the effect of mifepristone on heparin-binding epidermal growth factor (HB-EGF) and its receptors HER1 and HER4 in the fallopian tube and in the endometrium. DESIGN:Prospective clinical study. SETTING:Hospital-based unit for obstetrics and gynecology and research laboratories. PATIENT(S):Healthy wo...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2005.08.011

    authors: Sun XX,Gemzell-Danielsson K,Li HZ,Stâbi B,Stavreus-Evers A

    更新日期:2006-01-01 00:00:00

  • Effect of a phosphodiesterase type 3 inhibitor in oocyte maturation medium on subsequent mouse embryo development.

    abstract:OBJECTIVE:To investigate the effect of a phosphodiesterase type 3 inhibitor in oocyte maturation medium on subsequent embryo development. DESIGN:Animal study. SETTING:University laboratory. ANIMAL(S):CD-1 mice. INTERVENTION(S):Immature oocytes were arrested meiotically in medium containing a specific phosphodiester...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.03.041

    authors: Jee BC,Chen HY,Chian RC

    更新日期:2009-05-01 00:00:00

  • Fertilization and cleavage after reinsemination of human oocytes in vitro.

    abstract::The results of reinsemination of 150 morphologically mature oocytes that failed to fertilize within 15 to 20 hours after initial insemination were evaluated. Only 41 oocytes (27.3%) were fertilized after reinsemination, which is significantly lower than the percentage obtained after initial insemination (74%). However...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)49097-7

    authors: Ben-Rafael Z,Kopf GS,Blasco L,Tureck RW,Mastroianni L Jr

    更新日期:1986-01-01 00:00:00

  • Assessment of ovarian and uterine blood flow by transvaginal color Doppler in ovarian-stimulated women: correlation with the number of follicles and steroid hormone levels.

    abstract:OBJECTIVE:To study the changes that occur in vascular resistance to flow in the utero-ovarian circulation and their correlation with the number of follicles and steroid hormone levels in patients undergoing ovarian stimulation with gonadotropin. DESIGN:In a prospective study, the impedance to flow in the intraovarian ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55853-1

    authors: Weiner Z,Thaler I,Levron J,Lewit N,Itskovitz-Eldor J

    更新日期:1993-04-01 00:00:00

  • Sextuplets: an unusual complication of single embryo transfer.

    abstract:OBJECTIVE:To describe an unusual case of a sextuplet gestation after IVF and transfer of a single blastocyst. DESIGN:Case report. SETTING:University-based IVF clinic. PATIENT(S):A 32-year-old female with secondary infertility undergoing IVF-ET. INTERVENTION(S):Transvaginal oocyte retrieval, transfer of a single bla...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.09.021

    authors: Mains L,Ryan G,Sparks A,Van Voorhis B

    更新日期:2009-03-01 00:00:00

  • Does a woman's educational attainment influence in vitro fertilization outcomes?

    abstract::The association between educational level and cycle outcomes was quantified by applying multivariable logistic and linear regression within a prospective cohort of 2,569 women commencing their first in vitro fertilization (IVF) cycle. Although a woman's educational attainment was not associated with the likelihood of ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2011.05.015

    authors: Mahalingaiah S,Berry KF,Hornstein MD,Cramer DW,Missmer SA

    更新日期:2011-06-30 00:00:00