Older first-time mothers and early postpartum depression: a prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies.

Abstract:

OBJECTIVE:To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression. DESIGN:Prospective cohort study. SETTING:Assisted reproductive technology (ART) clinics in two large Australian cities and public and private antenatal clinics and/or classes in the vicinity of ART clinics. PATIENT(S):Nulliparous women who had conceived spontaneously (n = 295) or through ART (n = 297) in three age-groups: younger, 20 to 30 years (n = 173); middle, 31 to 36 years (n = 214); and older, ≥37 years (n = 189). INTERVENTION(S):Semistructured interviews and questionnaires. MAIN OUTCOME MEASURE(S):Major depressive disorder in the first 4 months after birth as assessed by structured diagnostic interview. RESULT(S):The study performed 592 complete pregnancy assessments and 541 postpartum assessments. The prevalence of major depressive disorder was 7.9%, at the lower end of community rates. Neither maternal age-group nor mode of conception was statistically significantly related to depression. CONCLUSION(S):Older first-time mothers, whether conceiving through ART or spontaneously, do not show increased vulnerability to postnatal depression.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

McMahon CA,Boivin J,Gibson FL,Fisher JR,Hammarberg K,Wynter K,Saunders DM

doi

10.1016/j.fertnstert.2011.08.037

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1218-24

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(11)02488-5

journal_volume

96

pub_type

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