当前位置： SCI文献检索 > FERTILITY AND STERILITY期刊下所有文献 > Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone.

Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone.

Abstract：

OBJECTIVE:To study the effect of mifepristone on heparin-binding epidermal growth factor (HB-EGF) and its receptors HER1 and HER4 in the fallopian tube and in the endometrium. DESIGN:Prospective clinical study. SETTING:Hospital-based unit for obstetrics and gynecology and research laboratories. PATIENT(S):Healthy women divided into two groups: controls and patients treated with a single dose of 200 mg mifepristone on day LH+2. INTERVENTION(S):Endometrial biopsies from 30 women were obtained during one control cycle or one treatment cycle. Fallopian tubes from 14 women were collected during laparoscopic sterilizations. MAIN OUTCOME MEASURE(S):Immunohistochemistry and reverse transcriptase-polymerase chain reaction. RESULT(S):The staining intensity of HB-EGF was not affected by mifepristone treatment. Treatment with mifepristone increased the immunostaining on HER1 in the epithelium and the stroma of the endometrium, which was not seen in the fallopian tube. The immunostaining of HER4 decreased in the stroma of the fallopian tube, while an increase was seen in the epithelial cells of the endometrium. CONCLUSION(S):Treatment with mifepristone has a limited effect on HB-EGF and its receptors in the fallopian tube, while the increase in HER1 and HER4 in the endometrium probably reflects defective endometrial maturation.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Sun XX,Gemzell-Danielsson K,Li HZ,Stâbi B,Stavreus-Evers A

doi

10.1016/j.fertnstert.2005.08.011

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

171-8

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(05)03603-4

journal_volume

85

pub_type

杂志文章

相关文献

FERTILITY AND STERILITY文献大全
  • Differences in hormonal characteristics of conceptive versus nonconceptive menstrual cycles.

    abstract：OBJECTIVE:To determine the hormonal characteristics of a fecund menstrual cycle. DESIGN:Prospective observational study. SETTING:Clinical research center. PATIENT(S):Fourteen patients having artificial insemination with donor semen provided daily blood and urine samples in a nonconceptive cycle and the consecutive c...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(00)01765-9

    authors： Li H,Nakajima ST,Chen J,Todd HE,Overstreet JW,Lasley BL

    更新日期：2001-03-01 00:00:00

  • Fluoroscopically guided synechiolysis for patients with Asherman's syndrome: menstrual and fertility outcomes.

    abstract：OBJECTIVE:To describe a 5-year experience of fluoroscopically guided hysteroscopic synechiolysis for Asherman's syndrome. DESIGN:Retrospective, uncontrolled cohort study. SETTING:Department of Endo-Gynaecology, University of New South Wales, Royal Hospital for Women, Randwick, Sydney, New South Wales, Australia. PAT...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2006.06.035

    authors： Thomson AJ,Abbott JA,Kingston A,Lenart M,Vancaillie TG

    更新日期：2007-02-01 00:00:00

  • Successful induction of ovulation using highly purified follicle-stimulating hormone in a woman with Kallmann's syndrome.

    abstract：OBJECTIVE:To describe a woman with Kallmann's syndrome who was treated successfully with highly purified FSH to achieve ovulation induction and pregnancy. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 32-year-old woman with Kallmann's syndrome who had been treated with oral contraceptives to prime se...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(99)00535-x

    authors： Battaglia C,Salvatori M,Regnani G,Giulini S,Primavera MR,Volpe A

    更新日期：2000-02-01 00:00:00

  • The effect of centchroman on serum luteinizing hormone in normal males.

    abstract：:Elevation of serum luteinizing hormone levels was observed in five normal male volunteers while they were taking Centchroman. This effect resembles that of clomiphene and suggests a new biologic potential of Centchroman. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)41785-1

    authors： Vaidya RA,Sheth A,Meherji P,Joshi L,Devi PK

    更新日期：1976-04-01 00:00:00

  • Selecting controls is not selecting "normals": design and analysis issues for studying the etiology of polycystic ovary syndrome.

    abstract：INTRODUCTION:Polycystic ovary syndrome (PCOS) is a highly prevalent disorder among postmenarcheal premenopausal women, accounting for much of anovulatory infertility, and it is associated with several comorbidities. The natural history of PCOS, as well as hypotheses regarding its etiology, facilitates employment of the...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2005.09.066

    authors： Bloom MS,Schisterman EF,Hediger ML

    更新日期：2006-07-01 00:00:00

  • Correlation between serum antichlamydial antibodies and tubal factor as a cause of infertility.

    abstract：:Although salpingitis frequently produces tubal damage and infertility, many women with tubal factor as a cause of their infertility do not have a clinical history of salpingitis. In order to investigate whether or not some such cases might be due to subclinical chlamydial infections, we measured antichlamydial antibod...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)46634-3

    authors： Jones RB,Ardery BR,Hui SL,Cleary RE

    更新日期：1982-11-01 00:00:00

  • Minimum standards for practices offering assisted reproductive technologies: a committee opinion.

    abstract：:This document is designed to provide a framework for assisted reproductive technology (ART) programs that meet or exceed the requirements suggested by the Centers for Disease Control and Prevention (CDC) for certification of ART laboratories. This document replaces the document, "Revised Minimum Standards for Practices...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,实务指引

    doi：10.1016/j.fertnstert.2019.11.024

    authors： Practice Committee of the American Society for Reproductive Medicine.,Practice Committee of the Society for Assisted Reproductive Technology.,Practice Committee of the Society of Reproductive Biologists and Technologists. Electronic address: asrm@as

    更新日期：2020-03-01 00:00:00

  • Experimental contamination assessment of a novel closed ultravitrification device.

    abstract：OBJECTIVE:To evaluate the safety of a new ultravitrification closed device. DESIGN:Ultravitrification research. SETTING:Private assisted reproduction center. ANIMAL(S):Microorganisms (bacteria). INTERVENTION(S):A styrofoam container holding 1,000 mL of liquid nitrogen (LN2) was contaminated with Pseudomonas aerugin...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2010.12.044

    authors： Criado E,Moalli F,Polentarutti N,Albani E,Morreale G,Menduni F,Levi-Setti PE

    更新日期：2011-04-01 00:00:00

  • Gamete intrafallopian tube transfer (GIFT): making laparoscopy more than "diagnostic".

    abstract：:Diagnostic laparoscopy is commonly performed on patients as part of a complete infertility investigation. Recently published protocols have investigated the efficacy of using empiric ovulation induction, intrauterine insemination, or both before beginning in vitro fertilization. Because many patients enrolled in these...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)60374-6

    authors： Barad DH,Bartfai G,Barg P,Cohen BL,Feinman M

    更新日期：1988-12-01 00:00:00

  • Ovarian reserve, response to gonadotropins, and oocyte maturity in women with malignancy.

    abstract：OBJECTIVE:To study the ovarian reserve, ovarian response to gonadotropins, and oocyte maturity in women with cancer undergoing in vitro fertilization (IVF) before chemotherapy or radiotherapy. DESIGN:Case-control study. SETTING:University teaching hospital. PATIENT(S):We evaluated all women with malignancy who under...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2011.04.070

    authors： Das M,Shehata F,Moria A,Holzer H,Son WY,Tulandi T

    更新日期：2011-07-01 00:00:00

  • Mutation frequency of cystic fibrosis transmembrane regulator is not increased in oligozoospermic male candidates for intracytoplasmic sperm injection.

    abstract：OBJECTIVE:To examine the frequency of anomalies of the vas deferens and the frequency of mutations of the cystic fibrosis transmembrane regulator (CFTR) gene in male candidates for intracytoplasmic sperm injection (ICSI) who had severe oligoasthenoteratozoospermia. DESIGN:The clinical data for male candidates for ICSI...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(98)00050-8

    authors： Tuerlings JH,Mol B,Kremer JA,Looman M,Meuleman EJ,te Meerman GJ,Buys CH,Merkus HM,Scheffer H

    更新日期：1998-05-01 00:00:00

  • Levels and associations among self-esteem, fertility distress, coping, and reaction to potentially being a genetic carrier in women with diminished ovarian reserve.

    abstract：OBJECTIVE:To measure the level of distress and its relationship with other psychologic factors in women with diminished ovarian reserve (DOR) who participated in a fragile X genetics study. DESIGN:Longitudinal data analyzed with structural equation modeling. SETTING:Four U.S. private and academic fertility centers. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.fertnstert.2013.02.033

    authors： Cizmeli C,Lobel M,Franasiak J,Pastore LM

    更新日期：2013-06-01 00:00:00

  • Lack of correlation between oocyte-corona-cumulus complex morphology and nuclear maturity of oocytes collected in stimulated cycles for intracytoplasmic sperm injection.

    abstract：OBJECTIVE:To evaluate the usefulness of morphology grading of the oocyte-corona-cumulus complex (OCCC) as a marker of oocyte nuclear maturity, fertilizability, embryo cleavage, and likelihood of pregnancy. DESIGN:Prospective cohort study. SETTING:Academic fertility center. PATIENT(S):Eighty-three infertile couples u...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(99)00100-4

    authors： Rattanachaiyanont M,Leader A,Léveillé MC

    更新日期：1999-05-01 00:00:00

  • Metabolism of triglyceride-rich lipoproteins and lipid transfer to high-density lipoprotein in young obese and normal-weight patients with polycystic ovary syndrome.

    abstract：OBJECTIVE:To clarify whether the metabolism of triglyceride-rich lipoproteins and lipid transfer to high-density lipoprotein (HDL) are altered in patients with polycystic ovary syndrome (PCOS). DESIGN:Case-control study. SETTING:Endocrinology clinics. PATIENT(S):Eight normal-weight (NW) and 15 obese (Ob) patients wi...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.12.044

    authors： Rocha MP,Maranhão RC,Seydell TM,Barcellos CR,Baracat EC,Hayashida SA,Bydlowski SP,Marcondes JA

    更新日期：2010-04-01 00:00:00

  • Male obesity and alteration in sperm parameters.

    abstract：OBJECTIVE:To study the effect of male obesity on sperm parameters and erectile dysfunction. DESIGN:Retrospective analysis. SETTING:Referral fertility center. PATIENT(S):Couples presenting for infertility treatment. INTERVENTION(S):On presentation, all men reported their weight and height and filled out an intake fo...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2007.10.011

    authors： Hammoud AO,Wilde N,Gibson M,Parks A,Carrell DT,Meikle AW

    更新日期：2008-12-01 00:00:00

  • Sex selection by sperm separation and insemination.

    abstract：:The Ericsson albumin filtration technique was used to collect a fraction rich in Y sperm for selective insemination in couples desiring a male infant. Of 35 conceptions in which sex was known at delivery or spontaneous abortion, there were 28 males (80%). Twelve pregnancies were achieved after separation of sperm in a...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Corson SL,Batzer FR,Alexander NJ,Schlaff S,Otis C

    更新日期：1984-11-01 00:00:00

  • Gestrinone versus danazol as preoperative treatment for hysteroscopic surgery: a prospective, randomized evaluation.

    abstract：OBJECTIVE:To compare danazol and gestrinone treatment as preoperative endometrial preparation for operative hysteroscopy. DESIGN:Prospective, randomized clinical study. SETTING:University department of gynecological, obstetrical sciences and reproductive medicine. PATIENT(S):One hundred thirty-five patients with end...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.fertnstert.2005.09.034

    authors： Triolo O,De Vivo A,Benedetto V,Falcone S,Antico F

    更新日期：2006-04-01 00:00:00

  • Is chromosome testing of the second miscarriage cost saving? A decision analysis of selective versus universal recurrent pregnancy loss evaluation.

    abstract：OBJECTIVE:To compare the cost of selective recurrent pregnancy loss (RPL) evaluation, which is defined as RPL evaluation if the second miscarriage is euploid, versus universal RPL evaluation, which is defined as RPL evaluation after the second miscarriage. Traditionally, an RPL evaluation is instituted after the third ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2012.03.038

    authors： Bernardi LA,Plunkett BA,Stephenson MD

    更新日期：2012-07-01 00:00:00

  • Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and steroidogenesis in ovarian cells.

    abstract：OBJECTIVE:To examine the effect of a gonadotropin-releasing hormone agonist (GnRH-a), leuprolide acetate (LA), on human chorionic gonadotropin/luteinizing hormone (LH) receptors content and progesterone (P) and estradiol (E2) production in cultured granulosa or luteal cells. DESIGN:Prospective. SETTING:Private Fertil...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Guerrero HE,Stein P,Asch RH,de Fried EP,Tesone M

    更新日期：1993-04-01 00:00:00

  • Tamoxifen treatment in male infertility. I. Effect on spermatozoa.

    abstract：OBJECTIVE:To evaluate the effects of tamoxifen treatment on sperm density, motility, vitality, and morphology. DESIGN:Placebo-controlled, randomized study. SETTING:Outpatient department. INTERVENTIONS:Patients were assigned to two comparable groups: group A (n = 122) was treated with 10 mg tamoxifen twice daily for ...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0015-0282(16)56705-3

    authors： Kotoulas IG,Cardamakis E,Michopoulos J,Mitropoulos D,Dounis A

    更新日期：1994-05-01 00:00:00

  • The role of MSP I CYP1A1 gene polymorphism in the development of uterine fibroids.

    abstract：:The cytochrome P-450 1A1 (CYPA1A) gene plays an important role in the metabolization of estrogen and is therefore a candidate marker for fibroids. In a case-control study, we were unable to demonstrate any association between MSP I CYP1A1 polymorphism and the risk of leiomyoma in Brazilian women. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2010.05.034

    authors： Barão MA,Oliveira E,Gomes MT,da Silva ID,Sartori MG,Girão MJ,Castro Rde A

    更新日期：2010-12-01 00:00:00

  • The effect of intrauterine devices containing zinc and copper on their levels in serum.

    abstract：:Serum levels of copper and zinc were determined in 11 health women in whom Latex Leaf intrauterine devices (IUDs) containing copper and zinc had been inserted. Patients with low levels of serum copper or zinc before insertion usually had increased levels of either of these metals while using the device, but they did n...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)43032-3

    authors： Anteby SO,Bassat HA,Yarkoni S,Aboulafia Y,Sadovsky E

    更新日期：1978-01-01 00:00:00

  • Clinical outcome of using ganirelix acetate versus a 4-day follicular phase leuprolide acetate protocol in unselected women undergoing in vitro fertilization.

    abstract：OBJECTIVE:To compare the clinical outcome of controlled ovarian hyperstimulation (COH) in unselected patients undergoing IVF using multidose ganirelix acetate versus 4 days of administration of leuprolide acetate. DESIGN:Retrospective cohort study. SETTING:A fertility and IVF center. PATIENT(S):Two hundred forty-sev...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(03)00500-4

    authors： Posada MN,Vlahos NP,Jurema MW,Bracero NJ,Wallach EE,Garcia JE

    更新日期：2003-07-01 00:00:00

  • Growth hormone enhances estradiol production follicle-stimulating hormone-induced in the early stage of the follicular maturation.

    abstract：OBJECTIVE:To investigate the ability of GH to increase the steroidogenic response of the ovary to FSH in the early stage of human follicle development in vivo. DESIGN:Ovarian sensitivity to FSH and/or GH during the early follicular phase of the human menstrual cycle was evaluated in a prospective study. SETTING:Norma...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0015-0282(16)58688-9

    authors： Lanzone A,Fortini A,Fulghesu AM,Soranna L,Caruso A,Mancuso S

    更新日期：1996-12-01 00:00:00

  • Prevention of gestational diabetes by metformin plus diet in patients with polycystic ovary syndrome.

    abstract：OBJECTIVE:To prospectively assess whether metformin diet safely provides primary and secondary prevention of gestational diabetes (GD). DESIGN:Assess development of GD on metformin diet. SETTING:Outpatient clinical research center. PATIENT(S):One hundred forty-two nondiabetic women with polycystic ovary syndrome (PC...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.fertnstert.2007.03.036

    authors： Glueck CJ,Pranikoff J,Aregawi D,Wang P

    更新日期：2008-03-01 00:00:00

  • Embryo transfer technique as a cause of ectopic pregnancies in in vitro fertilization.

    abstract：:Against an overall risk of around 2% ectopic pregnancies in in vitro fertilization programs around the world, we report an incidence more than three times greater (5 tubal ectopic pregnancies in 80 clinical in vitro fertilization pregnancies). Of two techniques used for embryo transfers, one produced a significantly h...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48854-0

    authors： Yovich JL,Turner SR,Murphy AJ

    更新日期：1985-09-01 00:00:00

  • Effect of sperm treatment with exogenous platelet-activating factor on the outcome of intrauterine insemination.

    abstract：OBJECTIVE:To evaluate the effect of sperm treatment with exogenous platelet-activating factor (PAF) on IUI clinical pregnancy rate. DESIGN:Prospective randomized study. SETTING:Assisted Reproduction Unit, 2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece. SUBJECT(...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.fertnstert.2004.07.980

    authors： Grigoriou O,Makrakis E,Konidaris S,Hassiakos D,Papadias K,Baka S,Creatsas G

    更新日期：2005-03-01 00:00:00

  • Serum bioactive and immunoreactive follicle-stimulating hormone in oligozoospermic and azoospermic men: application of a modified granulosa cell bioassay.

    abstract：:Serum follicle-stimulating hormone (FSH) levels measured by radioimmunoassay (RIA) usually correlate well with the rate of spermatogenesis. However, in certain cases this correlation does not exist. The purpose of this study was to establish a reliable bioassay of FSH for the andrological clinic. Follicle-stimulating ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)53469-4

    authors： Matzkin H,Homonnai ZT,Galiani D,Paz G,Dekel N

    更新日期：1990-04-01 00:00:00

  • Evaluation of quantitative polymerase chain reaction markers for the detection of breast cancer cells in ovarian tissue stored for fertility preservation.

    abstract：OBJECTIVE:To develop molecular tools increasing the sensitivity of breast cancer micrometastases detection within ovarian tissue cryopreserved for fertility preservation. DESIGN:Expression of breast markers was evaluated by quantitative polymerase chain reaction in ovarian tissue from patients with benign or cancerous...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2015.04.036

    authors： Bockstaele L,Boulenouar S,Van Den Steen G,Dechène J,Tsepelidis S,Craciun L,Noël JC,Demeestere I

    更新日期：2015-08-01 00:00:00

  • Increase in nerve fibers and loss of mast cells in polycystic and postmenopausal ovaries.

    abstract：OBJECTIVE:To quantify nerve fibers and mast cells in human ovaries at different functional stages. DESIGN:Retrospective study. SETTING:Research laboratory of the university. SPECIMEN(S): 8 human ovaries in the follicular (cyclic) phase, 7 polycystic ovaries, and postmenopausal ovaries with (n=5) or without (n=7) hype...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(01)01805-2

    authors： Heider U,Pedal I,Spanel-Borowski K

    更新日期：2001-06-01 00:00:00