当前位置： SCI文献检索 > FERTILITY AND STERILITY期刊下所有文献 > Clinical outcome of using ganirelix acetate versus a 4-day follicular phase leuprolide acetate protocol in unselected women undergoing in vitro fertilization.

Clinical outcome of using ganirelix acetate versus a 4-day follicular phase leuprolide acetate protocol in unselected women undergoing in vitro fertilization.

Abstract：

OBJECTIVE:To compare the clinical outcome of controlled ovarian hyperstimulation (COH) in unselected patients undergoing IVF using multidose ganirelix acetate versus 4 days of administration of leuprolide acetate. DESIGN:Retrospective cohort study. SETTING:A fertility and IVF center. PATIENT(S):Two hundred forty-seven women who underwent COH-IVF between April 1, 1999, and January 30, 2001. INTERVENTION(S):Pituitary suppression according to a 4-day follicular phase leuprolide acetate protocol (236 women) or a multidose ganirelix acetate regimen (133 women). MAIN OUTCOME MEASURE(S):Amount of gonadotropin used, days of stimulation, cancellation rate, number of oocytes retrieved, implantation rate, and clinical pregnancy rate. RESULT(S):Compared with leuprolide acetate recipients, ganirelix recipients required significantly less gonadotropin and the mean day of hCG administration was 4 days earlier. Among women younger than 35 years of age, the implantation rate (15% vs. 6%) and the clinical pregnancy rate per initiated and transferred cycle (27% vs. 12% and 32% vs. 15%, respectively) were significantly higher in the ganirelix group than the leuprolide acetate group. CONCLUSION(S):Compared with a 4-day leuprolide acetate protocol, COH-IVF using a multidose ganirelix acetate protocol reduces treatment duration and amount of gonadotropin used. In younger women, the latter protocol is associated with significantly better pregnancy and implantation rates.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Posada MN,Vlahos NP,Jurema MW,Bracero NJ,Wallach EE,Garcia JE

doi

10.1016/s0015-0282(03)00500-4

keywords:

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

103-10

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015028203005004

journal_volume

80

pub_type

杂志文章

相关文献

FERTILITY AND STERILITY文献大全
  • Characterization of exosomes in peritoneal fluid of endometriosis patients.

    abstract：OBJECTIVE:To demonstrate the feasibility of studying exosomes directly from peritoneal fluid, we isolated exosomes from endometriosis patient samples and from controls, and characterized their cargo. DESIGN:Case-control experimental study. SETTING:Academic clinical center. PATIENT (S):Women with and without endometr...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2019.09.032

    authors： Nazri HM,Imran M,Fischer R,Heilig R,Manek S,Dragovic RA,Kessler BM,Zondervan KT,Tapmeier TT,Becker CM

    更新日期：2020-02-01 00:00:00

  • Effects of low-dose estrogen oral contraceptives on weight, body composition, and fat distribution in young women.

    abstract：OBJECTIVE:To determine prospectively whether the use of low-dose estrogen oral contraceptives (OC) is associated with changes in weight, body composition, or fat distribution. DESIGN:Anthropometric measurements were performed in 49 healthy young (16 to 21 years old) women before commencement of OC use (30 micrograms e...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0015-0282(16)57419-6

    authors： Reubinoff BE,Grubstein A,Meirow D,Berry E,Schenker JG,Brzezinski A

    更新日期：1995-03-01 00:00:00

  • Interleukin-8 gene and protein expression are up-regulated by interleukin-1beta in normal human ovarian cells and a granulosa tumor cell line.

    abstract：OBJECTIVE:To evaluate the expression, regulation, and role of interleukin (IL)-8 in human ovary. DESIGN:Prospective study. SETTING:University hospital. PATIENT(S):Sixteen premenopausal women. INTERVENTION:Follicular fluid and granulosa lutein cells (GLCs) were collected during IVF cycles. Ovarian stromal and theca ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(02)04408-4

    authors： Fujii A,Harada T,Yamauchi N,Iwabe T,Nishi Y,Yanase T,Nawata H,Terakawa N

    更新日期：2003-01-01 00:00:00

  • Impact of fertility treatment on severe maternal morbidity.

    abstract：OBJECTIVE:To determine if fertility treatment is associated with increased risk of severe maternal morbidity (SMM) compared with spontaneous pregnancies. DESIGN:Retrospective cohort study. SETTING:Academic medical center. PATIENT(S):In 2012, 6,543 women delivered live births >20 weeks gestation at our center. Women ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2016.03.039

    authors： Wang ET,Ozimek JA,Greene N,Ramos L,Vyas N,Kilpatrick SJ,Pisarska MD

    更新日期：2016-08-01 00:00:00

  • Nicotine induces apoptosis in TM3 mouse Leydig cells.

    abstract：OBJECTIVE:To investigate whether nicotine-induced testicular toxicity involves the induction of apoptosis in Leydig cells. DESIGN:Cell study using cells of the TM3 cell line derived from mouse Leydig cells. SETTING:Academic research laboratory. INTERVENTION(S):Morphological and biochemical analyses for the detection...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2004.12.013

    authors： Kim KH,Joo KJ,Park HJ,Kwon CH,Jang MH,Kim CJ

    更新日期：2005-04-01 00:00:00

  • Paradoxical effects of D-Trp6-luteinizing hormone-releasing hormone on the hypothalamic-pituitary-gonadal axis in immature female rats.

    abstract：:The effect of administration of a superactive and long-acting analog of luteinizing hormone-releasing hormone (LH-RH), D-Trp6-LH-RH, in doses of 0.05 or 1 microgram/day for 10 days on the hypothalamic-pituitary-gonadal axis was studied in immature female rats. Treatment with a 0.05-microgram dose of analog produced fe...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)44061-6

    authors： Vilchez-Martinez JA,Pedroza E,Arimura A,Schally AV

    更新日期：1979-06-01 00:00:00

  • Adult somatic cells to the rescue: nuclear reprogramming and the dispensability of gonadal germ cells.

    abstract：:With advances in cancer therapies, survival rates in prepubescent patients have steadily increased. However, a number of these surviving patients have been rendered sterile owing to their rigorous oncologic treatment regimens. In addition to cancer treatments, men and women, who are genetically fertile, can become inf...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2013.11.025

    authors： Easley CA 4th,Latov DR,Simerly CR,Schatten G

    更新日期：2014-01-01 00:00:00

  • Lack of correlation between oocyte-corona-cumulus complex morphology and nuclear maturity of oocytes collected in stimulated cycles for intracytoplasmic sperm injection.

    abstract：OBJECTIVE:To evaluate the usefulness of morphology grading of the oocyte-corona-cumulus complex (OCCC) as a marker of oocyte nuclear maturity, fertilizability, embryo cleavage, and likelihood of pregnancy. DESIGN:Prospective cohort study. SETTING:Academic fertility center. PATIENT(S):Eighty-three infertile couples u...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(99)00100-4

    authors： Rattanachaiyanont M,Leader A,Léveillé MC

    更新日期：1999-05-01 00:00:00

  • Seminal fluid and fertility in women.

    abstract：:Seminal fluid is often viewed as simply a vehicle to carry sperm to fertilize the oocyte, but a more complex function in influencing female reproductive physiology is now evident. Remarkably, seminal fluid contains soluble and exosome-born signaling agents that interact with the female reproductive tract to prime the ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2016.07.1101

    authors： Robertson SA,Sharkey DJ

    更新日期：2016-09-01 00:00:00

  • Role of endocrine status and cell type in adhesion of human endometrial cells to the peritoneum in nude mice.

    abstract：OBJECTIVE:To investigate the role of different cellular types (epithelial and stromal endometrial cells and peritoneal cells) in the ectopic implantation of endometrium and to evaluate the importance of endocrine environment on the adhesion of endometrial cells to the peritoneum. DESIGN:Experimental prospective study....

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(02)03370-8

    authors： Beliard A,Noël A,Goffin F,Frankenne F,Foidart JM

    更新日期：2002-11-01 00:00:00

  • Contrast infusion sonography to assess microinsert placement and tubal occlusion after Essure.

    abstract：OBJECTIVE:To develop a technique for contrast infusion sonography and assess the possible use in determining microinsert placement and tubal status after Essure sterilization. DESIGN:Techniques and instrumentation. SETTING:Healthy women in an academic multispecialty group. PATIENT(S):Ten women desiring permanent ste...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.fertnstert.2005.10.075

    authors： Connor VF

    更新日期：2006-06-01 00:00:00

  • Large-needle percutaneous aspiration biopsy of the testicle in men with nonobstructive azoospermia.

    abstract：:Two hundred thirteen testicular specimens of men with nonobstructive azoospermia were obtained by large-needle percutaneous aspiration biopsy. The mean values of the number of seminiferous tubules per histologic section, dimension, weight, and the fraction of biopsies with spermatogenetic cells (53, 0.2 x 0.3 x 0.62 c...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2005.12.053

    authors： Carpi A,Fabris FG,Todeschini G,Nardini V

    更新日期：2006-08-01 00:00:00

  • Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer.

    abstract：OBJECTIVE:To identify the cumulus cell gene expression associated with oocyte developmental competence, specifically live birth, after single ET (SET) assisted reproductive technology. DESIGN:Retrospective gene expression analysis in human cumulus cells from oocytes that established a pregnancy resulting in live birth...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2011.04.033

    authors： Gebhardt KM,Feil DK,Dunning KR,Lane M,Russell DL

    更新日期：2011-07-01 00:00:00

  • Live birth of twins derived from zona-free oocytes.

    abstract：OBJECTIVE:To report a live birth of twins from autologous zona-free oocytes. DESIGN:Case report. SETTING:Reproductive endocrinology and infertility private practice and ambulatory in vitro fertilization (IVF) center. PATIENT(S):A 34-year-old woman, gravida 0, with 100% zona-free oocytes. INTERVENTION(S):IVF with in...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2016.01.023

    authors： Hu Y,Trolice MP

    更新日期：2016-05-01 00:00:00

  • Endometrial thickness and pregnancy outcome after intrauterine insemination.

    abstract：OBJECTIVES:To investigate whether endometrial thickness on the day of hCG administration is a predictor of intrauterine insemination (IUI) success. DESIGN:A retrospective study. PATIENT(S):Two hundred forty-nine women undergoing IUI cycles. SETTING:University hospital-based infertility center. INTERVENTION(S):Endom...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2006.12.010

    authors： Esmailzadeh S,Faramarzi M

    更新日期：2007-08-01 00:00:00

  • Gonadotropin suppression for the treatment of karyotypically normal spontaneous premature ovarian failure: a controlled trial.

    abstract：OBJECTIVE:To determine if gonadotropin suppression improves ovarian follicle function or ovulation rates in patients with karyotypically normal spontaneous premature ovarian failure. DESIGN:Prospective, double-blind, placebo-controlled, crossover trial. SETTING:Tertiary care research institution. INTERVENTIONS:Two i...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0015-0282(16)54775-x

    authors： Nelson LM,Kimzey LM,White BJ,Merriam GR

    更新日期：1992-01-01 00:00:00

  • Effect of sperm treatment with exogenous platelet-activating factor on the outcome of intrauterine insemination.

    abstract：OBJECTIVE:To evaluate the effect of sperm treatment with exogenous platelet-activating factor (PAF) on IUI clinical pregnancy rate. DESIGN:Prospective randomized study. SETTING:Assisted Reproduction Unit, 2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece. SUBJECT(...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.fertnstert.2004.07.980

    authors： Grigoriou O,Makrakis E,Konidaris S,Hassiakos D,Papadias K,Baka S,Creatsas G

    更新日期：2005-03-01 00:00:00

  • Autoimmunity and reproduction.

    abstract：OBJECTIVE:To review the association between autoimmunity and reproductive failure. DESIGN:A MEDLINE search done from 1965 to 1996. More than 300 original and review articles were evaluated, from which the most relevant were selected. RESULT(S):Autoimmune processes now are accepted widely as one of the possible mechan...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/s0015-0282(97)81351-9

    authors： Geva E,Amit A,Lerner-Geva L,Lessing JB

    更新日期：1997-04-01 00:00:00

  • Assessing brain-derived neurotrophic factor as a novel clinical marker of endometriosis.

    abstract：OBJECTIVE:To evaluate novel clinical markers of endometriosis including the neurotrophins brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and neurotrophin 4/5 (NT4/5) and compare them to others previously reported in the literature including cancer antigen 125 (CA-125) and C-reactive protein (CRP)....

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2015.09.003

    authors： Wessels JM,Kay VR,Leyland NA,Agarwal SK,Foster WG

    更新日期：2016-01-01 00:00:00

  • A new real-time morphology classification for human spermatozoa: a link for fertilization and improved embryo quality.

    abstract：OBJECTIVE:To understand the correlation between normalcy of the sperm, fertilization, and early embryo development, and to establish a detailed classification scoring scale for the individual spermatozoon with the highest predictive fertilizing potential in real time during intracytoplasmic sperm injection (ICSI). DES...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.08.088

    authors： Cassuto NG,Bouret D,Plouchart JM,Jellad S,Vanderzwalmen P,Balet R,Larue L,Barak Y

    更新日期：2009-11-01 00:00:00

  • A study of prolactin, follicle-stimulating hormone, and luteinizing hormone in puerperium: spontaneous variations and the effect of metergoline.

    abstract：:In 80 normal puerperae, serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), including human chorionic gonadotropin (hCG/LH), and prolactin (PRL) levels were evaluated 6 to 29 hours after vaginal delivery. In these puerperae, PRL levels were higher and FSH levels were lower than in menstruating women; h...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)46103-0

    authors： Falsetti L,Voltolini AM,Pollini C,Pontiroli AE

    更新日期：1982-03-01 00:00:00

  • Quality of reporting of test accuracy studies in reproductive medicine: impact of the Standards for Reporting of Diagnostic Accuracy (STARD) initiative.

    abstract：OBJECTIVE:To evaluate the extent to which test accuracy studies published in two leading reproductive medicine journals in the years 1999 and 2004 adhered to the Standards for Reporting of Diagnostic Accuracy (STARD) initiative parameters, and to explore whether the introduction of the STARD statement has led to an imp...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2006.03.050

    authors： Coppus SF,van der Veen F,Bossuyt PM,Mol BW

    更新日期：2006-11-01 00:00:00

  • Total acrosin activity correlates with fertility potential after fertilization in vitro.

    abstract：OBJECTIVE:To evaluate the possible relationship between total acrosin activity in spermatozoa and fertility potential after fertilization in vitro. DESIGN:Total acrosin activity of spermatozoa was measured in 101 in vitro fertilization (IVF) cases by an observer unaware of fertilization and cleavage results. SETTING:...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Tummon IS,Yuzpe AA,Daniel SA,Deutsch A

    更新日期：1991-11-01 00:00:00

  • Assisted reproductive technologies (ART) in Canada: 2001 results from the Canadian ART Register.

    abstract：OBJECTIVE:To present the success rates of assisted reproductive technologies (ART) cycles performed in 2001 in Canada. DESIGN:Retrospective cohort study. SETTING:Nineteen of 22 ART centers in Canada. PARTICIPANTS:Couples undergoing ART treatment in Canada during 2001. METHODS:Data on each ART cycle performed during...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2005.03.037

    authors： Gunby J,Daya S,IVF Directors Group of the Canadian Fertility and Andrology Society.

    更新日期：2005-09-01 00:00:00

  • Now you see them, now you don't.

    abstract：:Tissue integrity of the regurgitated endometrium is pivotal to the development of endometriosis. Occult, submicroscopic lesions occur. Diagnostic laparoscopy may underestimate as well as overestimate the presence of endometriosis. ...

    journal_title：Fertility and sterility

    pub_type： 评论,杂志文章,评审

    doi：10.1016/j.fertnstert.2005.01.122

    authors： Evers JL,Dunselman GA,Groothuis P

    更新日期：2005-07-01 00:00:00

  • Triple ultrasound markers including fetal cardiac activity are related to miscarriage risk.

    abstract：OBJECTIVE:To identify early ultrasound markers in pregnant patients that predict a favorable pregnancy outcome. DESIGN:Retrospective case-control study. SETTING:Infertility patients in fertility clinic. PATIENT(S):1051 women with early pregnancies conceived after fertility treatment. INTERVENTION(S):None. MAIN OUT...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2011.08.009

    authors： Bae S,Karnitis J

    更新日期：2011-11-01 00:00:00

  • Intrauterine insemination-ready versus conventional semen cryopreservation for donor insemination: a comparison of retrospective results and a prospective, randomized trial.

    abstract：OBJECTIVE:To compare fecundity rates following intrauterine insemination (IUI) with donor sperm frozen conventionally versus an IUI-ready preparation. DESIGN:Both retrospective results and a prospective, randomized study where recipients were assigned to one of two sperm cryopreservation methods in each cycle of intra...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0015-0282(01)01857-x

    authors： Wolf DP,Patton PE,Burry KA,Kaplan PF

    更新日期：2001-07-01 00:00:00

  • The activity (calcium oscillator?) responsible for human oocyte activation after injection with round spermatids is associated with spermatid nuclei.

    abstract：OBJECTIVE:To compare the oocyte-activating ability of whole human round spermatids and their isolated nuclei. DESIGN:Prospective study using sibling oocytes from patients undergoing spermatid conception and intracytoplasmic sperm injection treatment cycles. SETTING:Private assisted reproduction laboratories and a uni...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(00)01598-3

    authors： Tesarik J,Mendoza C,Greco E

    更新日期：2000-12-01 00:00:00

  • Unilateral triplet ectopic pregnancy after in vitro fertilization and embryo transfer.

    abstract：OBJECTIVE:To present a case report of a unilateral triplet ectopic pregnancy (EP) conceived by IVF-embryo transfer. DESIGN:Case report. SETTING:University Hospital, Budapest, Hungary. PATIENT(S):A 26-year-old infertile woman with a history of right salpingectomy, hyperprolactinemia, and male factor infertility under...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.03.018

    authors： Berkes E,Szendei G,Csabay L,Sipos Z,Joo JG,Rigo J Jr

    更新日期：2008-11-01 00:00:00

  • Occupationally related exposures and reduced semen quality: a case-control study.

    abstract：OBJECTIVE:To determine whether there is an association between abnormal semen parameters and occupational exposures to organic solvents, metals, and pesticides. DESIGN:Case-control study using three case groups based on different cutoff values for semen parameters and one standard reference group. SETTING:University ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(98)00542-1

    authors： Tielemans E,Burdorf A,te Velde ER,Weber RF,van Kooij RJ,Veulemans H,Heederik DJ

    更新日期：1999-04-01 00:00:00